iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028804

UUCD1 version

UUC-DaR-01344

Ensembl Protein ID

ENSDARP00000141341.1

UniProt Accession

Q6PBX6; Q6PBX6_DANRE

Genbank Protein ID

AAH59548.1; AAI53622.1

Protein Name

Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast),-like

Genbank Nucleotide ID

CU929193; BC153621

Gene Name

ube2d2l; ube2d2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000099749.1	ENSDART00000168142.1	ENSDARP00000141341.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-55	188.0	5	139
UBD/UBC-like/UBD_UBC	5.90e-84	280.0	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l +dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RIHKELTDLGRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           99**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k+++e+y++++r
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDNEKYNRIAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel dl rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RIHKELTDLGRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDNEKYNRIAREWT 142
           ************************************************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MALKRIHKEL TDLGRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGAGAGA GGTGGAGACA CAATCACACA CGCTCATACA TACCTATACA AGTGCTCATT 60
GGAGAAGCTC AGGCCTTCCC GTTCACACTC TCTGTAACTT TGCTCCTCGG CGGGATTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

dre:335444

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008266	Aspergillus clavatus	86.39	1.00e-74	271.00
IUUC-Afu-008956	Aspergillus fumigatus	87.07	8.00e-75	272.00
IUUC-Ate-010438	Aspergillus terreus	85.71	9.00e-74	268.00
IUUC-Ame-011657	Astyanax mexicanus	98.63	1.00e-84	304.00
IUUC-Bci-013661	Botrytis cinerea	85.03	1.00e-74	271.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	85.71	3.00e-74	270.00
IUUC-Dse-031397	Dothistroma septosporum	85.71	2.00e-74	271.00
IUUC-Fox-038021	Fusarium oxysporum	85.71	4.00e-74	270.00
IUUC-Fso-038297	Fusarium solani	85.03	8.00e-74	268.00
IUUC-Kpa-049290	Komagataella pastoris	78.91	4.00e-69	253.00
IUUC-Lma-053121	Leptosphaeria maculans	85.71	1.00e-74	271.00
IUUC-Mor-057235	Magnaporthe oryzae	85.03	1.00e-73	268.00
IUUC-Nfi-068599	Neosartorya fischeri	87.07	8.00e-75	272.00
IUUC-Pno-094765	Phaeosphaeria nodorum	85.71	1.00e-74	271.00
IUUC-Pte-104015	Pyrenophora teres	85.71	2.00e-74	271.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	85.71	2.00e-74	271.00
IUUC-Sce-106153	Saccharomyces cerevisiae	81.94	1.00e-70	258.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	85.71	5.00e-75	272.00
IUUC-Vda-129695	Verticillium dahliae	85.71	3.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence