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Tag Content
UUCD2 ID IUUC-Cfa-020154
UUCD1 version UUC-CaF-00606
Ensembl Protein ID ENSCAFP00000014857.3
UniProt Accession F1PBV3; F1PBV3_CANLF
Genbank Protein ID ENSCAFP00000014857
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03002190
Gene Name UBE3A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000010110.3 ENSCAFT00000016065.3 ENSCAFP00000014857.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 4.30e-108 362.0 543 869
Active Site
Position(s) Description Evidence
838 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y+e+ k  ++ np+s+    e +  F+++G++lg+a++++ +ld+
   Q: 543  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWF-NPSSF----ETEGQFTLIGIVLGLAIYNNCILDV 626
           689******************************************998888876.88888....789********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.lgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl + +p ly+slk ++e+ e ++e+  + +tf++s++  +g+   ++Lk++G++ip+tneN++e+v+l+ 
   Q: 627  HFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEY-EGNVEDD-MMITFQISQTDlFGNPMMYDLKENGDKIPITNENRKEFVNLYS 713
           *************************************.7799986.99***9665444******************************* PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           +y+l++++++q++afr+Gf+ v +++ l  lF++ee+ellicG++++d+++l+++t+y+ggyt+ds  i+ Fwe++++f++e+++ fLq
   Q: 714  DYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQ 802
           ***********************99934558********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tg++r+P+gG+ +lk   ++i k++ d +rlP+s+TCfn+L LPeYsske+lke+Ll Ai+++kgF++
   Q: 803  FTTGTDRAPVGGLGKLK---MIIAKNGPDtERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 869
           *****************...8888866666**************************************97 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
YRSPGEPQSD DIEASRMKRA AAKHLIERYY HQLTEGCGNE ACTNEFCASC PTFLRMDNNA 60
AAIKALELYK INAKLCDPHP SKKGASSAYL ENSKGAPNNS CSDIKMNKKE GQGARDDFRD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020154|E3,HECT|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TACAGATCGC CAGGAGAACC TCAGTCTGAC GACATCGAAG CTAGCCGAAT GTAAGTGTAT 60
CTTGGTTGCA GCTGTGGTGT CTTTTAAGTT ACCCTAGATT GCTTTAAAGG TGTTATATTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020154|E3,HECT|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR032353--AZUL
IPR000569--HECT_dom
IPR017134--UBE3A
PROSITE

PS50237--HECT
Pfam

PF16558--AZUL
PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0030521--P:androgen receptor signaling pathway
GO:0001541--P:ovarian follicle development
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060736--P:prostate gland growth
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042752--P:regulation of circadian rhythm
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035037--P:sperm entry
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002214 Ailuropoda melanoleuca 98.24 0.00e+00 1625.00
IUUC-Atr-003144 Amborella trichopoda 45.80 4.00e-96 345.00
IUUC-Apl-003742 Anas platyrhynchos 93.82 0.00e+00 1595.00
IUUC-Aca-004873 Anolis carolinensis 93.96 0.00e+00 1614.00
IUUC-Ame-011166 Astyanax mexicanus 86.60 0.00e+00 1454.00
IUUC-Bta-013286 Bos taurus 96.44 0.00e+00 1600.00
IUUC-Cja-019707 Callithrix jacchus 96.79 0.00e+00 1630.00
IUUC-Cpo-021292 Cavia porcellus 96.14 0.00e+00 1588.00
IUUC-Cre-022790 Chlamydomonas reinhardtii 49.06 3.00e-82 298.00
IUUC-Csa-023378 Chlorocebus sabaeus 96.78 0.00e+00 1627.00
IUUC-Cho-025059 Choloepus hoffmanni 93.11 0.00e+00 1511.00
IUUC-Cin-025643 Ciona intestinalis 44.86 0.00e+00 717.00
IUUC-Csv-026282 Ciona savignyi 45.06 0.00e+00 673.00
IUUC-Cme-027151 Cyanidioschyzon merolae 44.02 2.00e-101 363.00
IUUC-Dre-027901 Danio rerio 85.76 0.00e+00 1436.00
IUUC-Dno-029320 Dasypus novemcinctus 97.13 0.00e+00 1630.00
IUUC-Dor-030756 Dipodomys ordii 92.22 0.00e+00 729.00
IUUC-Dme-032035 Drosophila melanogaster 43.21 3.00e-166 579.00
IUUC-Eca-033843 Equus caballus 96.96 0.00e+00 1588.00
IUUC-Eeu-035109 Erinaceus europaeus 94.73 0.00e+00 1543.00
IUUC-Fca-036344 Felis catus 97.47 0.00e+00 1650.00
IUUC-Fal-036747 Ficedula albicollis 93.82 0.00e+00 1596.00
IUUC-Gmo-038840 Gadus morhua 63.32 0.00e+00 1102.00
IUUC-Gga-040399 Gallus gallus 93.82 0.00e+00 1596.00
IUUC-Gac-041933 Gasterosteus aculeatus 84.45 0.00e+00 1398.00
IUUC-Ggo-044804 Gorilla gorilla 96.90 0.00e+00 1627.00
IUUC-Hsa-045727 Homo sapiens 96.90 0.00e+00 1627.00
IUUC-Itr-048289 Ictidomys tridecemlineatus 93.21 0.00e+00 1509.00
IUUC-Lch-050197 Latimeria chalumnae 90.47 0.00e+00 1541.00
IUUC-Loc-052743 Lepisosteus oculatus 89.13 0.00e+00 1535.00
IUUC-Lma-053245 Leptosphaeria maculans 33.87 5.00e-57 216.00
IUUC-Laf-053615 Loxodonta africana 95.16 0.00e+00 1597.00
IUUC-Mcc-054934 Macaca mulatta 97.12 0.00e+00 1623.00
IUUC-Meu-056061 Macropus eugenii 95.48 0.00e+00 1349.00
IUUC-Mga-059271 Meleagris gallopavo 92.67 0.00e+00 1563.00
IUUC-Mmr-061288 Microcebus murinus 96.77 0.00e+00 1623.00
IUUC-Mdo-062975 Monodelphis domestica 95.18 0.00e+00 1610.00
IUUC-Mmu-063674 Mus musculus 94.14 0.00e+00 1562.00
IUUC-Mpu-066568 Mustela putorius furo 98.51 0.00e+00 1662.00
IUUC-Mlu-067522 Myotis lucifugus 89.50 0.00e+00 1512.00
IUUC-Nle-069505 Nomascus leucogenys 96.90 0.00e+00 1627.00
IUUC-Opr-070570 Ochotona princeps 89.77 0.00e+00 1469.00
IUUC-Ont-071527 Oreochromis niloticus 85.47 0.00e+00 1468.00
IUUC-Oan-073446 Ornithorhynchus anatinus 91.40 0.00e+00 1055.00
IUUC-Ocu-074922 Oryctolagus cuniculus 96.01 0.00e+00 1625.00
IUUC-Ola-086996 Oryzias latipes 84.76 0.00e+00 1463.00
IUUC-Oga-088261 Otolemur garnettii 96.84 0.00e+00 1598.00
IUUC-Oar-090024 Ovis aries 96.44 0.00e+00 1600.00
IUUC-Ptr-090455 Pan troglodytes 96.90 0.00e+00 1627.00
IUUC-Pan-092509 Papio anubis 95.09 0.00e+00 1458.00
IUUC-Psi-092974 Pelodiscus sinensis 93.47 0.00e+00 1565.00
IUUC-Pma-094643 Petromyzon marinus 70.45 0.00e+00 1254.00
IUUC-Pno-094886 Phaeosphaeria nodorum 35.32 8.00e-58 219.00
IUUC-Pfo-096905 Poecilia formosa 84.96 0.00e+00 1466.00
IUUC-Pab-097840 Pongo abelii 95.90 0.00e+00 1565.00
IUUC-Pca-100869 Procavia capensis 95.79 0.00e+00 1580.00
IUUC-Pva-103040 Pteropus vampyrus 97.02 0.00e+00 667.00
IUUC-Rno-105453 Rattus norvegicus 94.02 0.00e+00 1560.00
IUUC-Sha-107651 Sarcophilus harrisii 95.18 0.00e+00 1610.00
IUUC-Smo-108858 Selaginella moellendorffii 49.88 2.00e-116 413.00
IUUC-Sar-113293 Sorex araneus 96.49 0.00e+00 1598.00
IUUC-Ssc-115979 Sus scrofa 97.07 0.00e+00 1603.00
IUUC-Tgu-116901 Taeniopygia guttata 93.82 0.00e+00 1595.00
IUUC-Tru-118368 Takifugu rubripes 85.10 0.00e+00 1465.00
IUUC-Tsy-119516 Tarsius syrichta 92.97 0.00e+00 1491.00
IUUC-Tni-120143 Tetraodon nigroviridis 84.66 0.00e+00 1460.00
IUUC-Tbe-127484 Tupaia belangeri 91.34 0.00e+00 1099.00
IUUC-Ttr-129078 Tursiops truncatus 96.49 0.00e+00 1590.00
IUUC-Vpa-130312 Vicugna pacos 88.82 0.00e+00 1367.00
IUUC-Xtr-132881 Xenopus tropicalis 90.47 0.00e+00 1551.00
Created Date 25-Jun-2017

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