iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006548.4	ENSCAFT00000010561.4	ENSCAFP00000009792.3
ENSCAFG00000006548.4	ENSCAFT00000036344.2	ENSCAFP00000031707.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.70e-99	332.0	75	264

Active Site

Position(s)	Description	Evidence
246	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 15   klksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleee 103
            l+++kvl++GagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg++KAevaae+l++++p++nv++h ++i++ +++
   Q: 75   LLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDT 163
           589***********************************************************************************999 PP
   S: 104  ivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlke 178
             F+++f+++v++ld++ arr++n +++++             vpli++gt+G++G++rvi++g+t+c++c+   +ppq+++P+ct+++
   Q: 164  --FYRQFHIIVCGLDSIIARRWINGMLISLlnyedgvldpssIVPLIDGGTEGFKGNARVILPGMTACIECTLelYPPQVNFPMCTIAS 250
           ..***************************9*********************************************************** PP
   S: 179  tpnaaehtiewavl 192
           +p+ +eh+ie++++
   Q: 251  MPRLPEHCIEYVRI 264
           ***********933 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MCSVMLTLLL FSLSFREKKR RRIEELLAEK MAVDGGCGDT GDWEGRWNHV KKFLERSGPF 60
THPDFEPSTE SLQFLLDTCK VLVIGAGGLG CELLKNLALS GFRQIHVIDM DTIDVSNLNR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATG GCGAGGAGCC GTAAGTACTC GGGCTCTGCA GGCGTGCGCG GTGGGCTGGG 60
CTGTGAGAGA GCGCGGCGCT GGGCGGTCGC TGCCGCCACC CGGGGTCCCC CCCCACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0007113--P:endomitotic cell cycle
GO:0045116--P:protein neddylation
GO:0051726--P:regulation of cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	47.73	8.00e-81	293.00
IUUC-Aml-001578	Ailuropoda melanoleuca	99.34	0.00e+00	946.00
IUUC-Atr-002591	Amborella trichopoda	50.37	4.00e-91	328.00
IUUC-Apl-003671	Anas platyrhynchos	90.56	0.00e+00	863.00
IUUC-Aca-004749	Anolis carolinensis	91.10	0.00e+00	827.00
IUUC-Aly-005747	Arabidopsis lyrata	47.64	6.00e-97	347.00
IUUC-Ath-006623	Arabidopsis thaliana	47.89	6.00e-97	347.00
IUUC-Ago-007934	Ashbya gossypii	44.65	2.00e-72	266.00
IUUC-Acl-008047	Aspergillus clavatus	49.65	1.00e-121	429.00
IUUC-Afl-008615	Aspergillus flavus	44.05	7.00e-80	290.00
IUUC-Afu-008996	Aspergillus fumigatus	50.47	7.00e-115	407.00
IUUC-Ani-009281	Aspergillus nidulans	43.29	6.00e-84	304.00
IUUC-Ang-009539	Aspergillus niger	50.59	6.00e-112	397.00
IUUC-Aor-010151	Aspergillus oryzae	48.44	4.00e-110	391.00
IUUC-Ate-010502	Aspergillus terreus	50.82	2.00e-113	402.00
IUUC-Ame-011837	Astyanax mexicanus	86.77	0.00e+00	792.00
IUUC-Bgr-012068	Blumeria graminis	50.48	1.00e-113	403.00
IUUC-Bta-013003	Bos taurus	99.55	0.00e+00	920.00
IUUC-Bci-013983	Botrytis cinerea	53.76	3.00e-124	438.00
IUUC-Bdi-014429	Brachypodium distachyon	49.00	4.00e-88	318.00
IUUC-Bol-015813	Brassica oleracea	48.64	3.00e-89	322.00
IUUC-Bra-018023	Brassica rapa	47.89	3.00e-86	312.00
IUUC-Cel-018684	Caenorhabditis elegans	53.50	1.00e-128	452.00
IUUC-Cja-019200	Callithrix jacchus	98.65	0.00e+00	908.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	49.27	2.00e-107	382.00
IUUC-Csa-024079	Chlorocebus sabaeus	98.87	0.00e+00	918.00
IUUC-Cho-025052	Choloepus hoffmanni	91.18	0.00e+00	825.00
IUUC-Cin-025113	Ciona intestinalis	68.55	0.00e+00	627.00
IUUC-Csv-026231	Ciona savignyi	67.21	0.00e+00	627.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	51.15	6.00e-125	441.00
IUUC-Cne-026850	Cryptococcus neoformans	48.24	4.00e-108	384.00
IUUC-Cme-027275	Cyanidioschyzon merolae	36.22	4.00e-68	252.00
IUUC-Dre-028751	Danio rerio	86.55	0.00e+00	801.00
IUUC-Dno-029571	Dasypus novemcinctus	98.94	0.00e+00	917.00
IUUC-Dor-030395	Dipodomys ordii	97.51	0.00e+00	887.00
IUUC-Dse-031329	Dothistroma septosporum	45.74	3.00e-104	372.00
IUUC-Dme-031776	Drosophila melanogaster	64.27	3.00e-161	561.00
IUUC-Ete-032894	Echinops telfairi	78.24	1.00e-70	260.00
IUUC-Eca-034389	Equus caballus	99.32	0.00e+00	921.00
IUUC-Eeu-035152	Erinaceus europaeus	86.57	0.00e+00	692.00
IUUC-Fca-036032	Felis catus	99.78	0.00e+00	929.00
IUUC-Fal-037506	Ficedula albicollis	89.66	0.00e+00	856.00
IUUC-Fox-037871	Fusarium oxysporum	53.85	1.00e-110	392.00
IUUC-Fso-038350	Fusarium solani	52.08	1.00e-122	432.00
IUUC-Gmo-039246	Gadus morhua	83.33	0.00e+00	776.00
IUUC-Ggr-039859	Gaeumannomyces graminis	53.13	3.00e-120	424.00
IUUC-Gga-040843	Gallus gallus	88.12	0.00e+00	825.00
IUUC-Gac-042601	Gasterosteus aculeatus	84.21	0.00e+00	793.00
IUUC-Gma-042744	Glycine max	50.39	3.00e-88	318.00
IUUC-Ggo-044788	Gorilla gorilla	98.87	0.00e+00	910.00
IUUC-Hsa-045849	Homo sapiens	99.32	0.00e+00	919.00
IUUC-Hvu-047819	Hordeum vulgare	51.00	3.00e-82	298.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	98.42	0.00e+00	914.00
IUUC-Kpa-049393	Komagataella pastoris	54.41	3.00e-103	367.00
IUUC-Lch-049471	Latimeria chalumnae	90.81	0.00e+00	837.00
IUUC-Lpe-051297	Leersia perrieri	48.32	2.00e-97	349.00
IUUC-Loc-052910	Lepisosteus oculatus	88.31	0.00e+00	814.00
IUUC-Lma-053181	Leptosphaeria maculans	49.89	2.00e-120	426.00
IUUC-Laf-054314	Loxodonta africana	98.21	0.00e+00	910.00
IUUC-Mcc-054870	Macaca mulatta	99.32	0.00e+00	919.00
IUUC-Meu-056574	Macropus eugenii	79.34	1.00e-131	463.00
IUUC-Mor-056919	Magnaporthe oryzae	54.19	3.00e-124	438.00
IUUC-Mpo-057614	Magnaporthe poae	54.57	8.00e-115	407.00
IUUC-Mtr-058110	Medicago truncatula	50.13	7.00e-89	320.00
IUUC-Mla-058949	Melampsora laricipopulina	53.30	8.00e-118	417.00
IUUC-Mga-059455	Meleagris gallopavo	90.34	0.00e+00	856.00
IUUC-Mvi-060270	Microbotryum violaceum	50.68	6.00e-119	421.00
IUUC-Mmr-061155	Microcebus murinus	93.91	0.00e+00	880.00
IUUC-Mdo-062037	Monodelphis domestica	96.25	0.00e+00	862.00
IUUC-Mmu-063670	Mus musculus	99.09	0.00e+00	915.00
IUUC-Mac-064711	Musa acuminata	48.39	6.00e-87	314.00
IUUC-Mpu-066734	Mustela putorius furo	99.33	0.00e+00	917.00
IUUC-Mlu-067068	Myotis lucifugus	99.06	0.00e+00	881.00
IUUC-Nfi-068349	Neosartorya fischeri	50.23	2.00e-114	405.00
IUUC-Ncr-068626	Neurospora crassa	52.75	4.00e-107	381.00
IUUC-Nle-069366	Nomascus leucogenys	90.83	0.00e+00	823.00
IUUC-Opr-070993	Ochotona princeps	92.31	3.00e-68	252.00
IUUC-Ont-072196	Oreochromis niloticus	85.78	0.00e+00	790.00
IUUC-Oan-073511	Ornithorhynchus anatinus	93.67	0.00e+00	881.00
IUUC-Ocu-073773	Oryctolagus cuniculus	98.87	0.00e+00	917.00
IUUC-Oba-075726	Oryza barthii	44.79	1.00e-85	310.00
IUUC-Obr-076286	Oryza brachyantha	47.36	3.00e-94	338.00
IUUC-Ogu-078473	Oryza glumaepatula	44.79	1.00e-85	310.00
IUUC-Oin-079393	Oryza indica	49.50	9.00e-100	357.00
IUUC-Olo-080446	Oryza longistaminata	46.39	2.00e-89	322.00
IUUC-Ome-081737	Oryza meridionalis	47.01	4.00e-89	321.00
IUUC-Oni-082853	Oryza nivara	44.79	1.00e-85	310.00
IUUC-Opu-083590	Oryza punctata	48.56	4.00e-99	354.00
IUUC-Oru-084184	Oryza rufipogon	44.79	1.00e-85	310.00
IUUC-Osa-085402	Oryza sativa	49.50	9.00e-100	357.00
IUUC-Ola-086615	Oryzias latipes	78.51	0.00e+00	728.00
IUUC-Olu-087738	Ostreococcus lucimarinus	48.40	4.00e-93	335.00
IUUC-Oga-088101	Otolemur garnettii	98.87	0.00e+00	916.00
IUUC-Oar-090293	Ovis aries	98.21	0.00e+00	913.00
IUUC-Ptr-090503	Pan troglodytes	99.32	0.00e+00	919.00
IUUC-Pan-092477	Papio anubis	96.85	0.00e+00	887.00
IUUC-Psi-093442	Pelodiscus sinensis	91.84	0.00e+00	860.00
IUUC-Pma-094247	Petromyzon marinus	80.58	0.00e+00	768.00
IUUC-Pno-094780	Phaeosphaeria nodorum	49.37	2.00e-114	405.00
IUUC-Ppa-095338	Physcomitrella patens	49.88	5.00e-116	410.00
IUUC-Pfo-097137	Poecilia formosa	85.34	0.00e+00	793.00
IUUC-Pab-098060	Pongo abelii	98.87	0.00e+00	878.00
IUUC-Pop-099470	Populus trichocarpa	47.44	7.00e-94	337.00
IUUC-Pca-100500	Procavia capensis	82.66	0.00e+00	738.00
IUUC-Ppe-102008	Prunus persica	48.44	2.00e-85	309.00
IUUC-Pva-103095	Pteropus vampyrus	100.00	4.00e-128	451.00
IUUC-Pgr-103666	Puccinia graminis	50.81	1.00e-115	410.00
IUUC-Ptt-103901	Puccinia triticina	51.29	3.00e-118	418.00
IUUC-Pte-104198	Pyrenophora teres	48.75	5.00e-119	421.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.07	6.00e-117	414.00
IUUC-Rno-105446	Rattus norvegicus	99.09	0.00e+00	915.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.68	4.00e-71	261.00
IUUC-Sha-106664	Sarcophilus harrisii	95.95	0.00e+00	863.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	43.02	5.00e-99	354.00
IUUC-Spo-108345	Schizosaccharomyces pombe	43.54	6.00e-98	351.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	49.18	6.00e-107	380.00
IUUC-Smo-109133	Selaginella moellendorffii	49.29	3.00e-115	408.00
IUUC-Sit-109724	Setaria italica	49.26	9.00e-91	327.00
IUUC-Sly-110916	Solanum lycopersicum	48.59	9.00e-95	340.00
IUUC-Stu-112236	Solanum tuberosum	48.33	2.00e-94	339.00
IUUC-Sar-113044	Sorex araneus	98.51	0.00e+00	821.00
IUUC-Sbi-114276	Sorghum bicolor	49.38	6.00e-91	327.00
IUUC-Sre-114963	Sporisorium reilianum	51.98	2.00e-118	419.00
IUUC-Ssc-116301	Sus scrofa	98.66	0.00e+00	912.00
IUUC-Tgu-117265	Taeniopygia guttata	89.44	0.00e+00	854.00
IUUC-Tru-117526	Takifugu rubripes	83.84	0.00e+00	775.00
IUUC-Tsy-119483	Tarsius syrichta	98.31	0.00e+00	848.00
IUUC-Tni-120363	Tetraodon nigroviridis	84.46	0.00e+00	769.00
IUUC-Tca-121731	Theobroma cacao	49.12	2.00e-88	319.00
IUUC-Tre-122221	Trichoderma reesei	53.32	2.00e-111	395.00
IUUC-Tvi-122352	Trichoderma virens	51.51	1.00e-123	436.00
IUUC-Tae-123864	Triticum aestivum	48.32	5.00e-90	325.00
IUUC-Tur-126070	Triticum urartu	45.82	1.00e-70	260.00
IUUC-Tme-127199	Tuber melanosporum	50.65	2.00e-109	388.00
IUUC-Tbe-128076	Tupaia belangeri	98.87	0.00e+00	916.00
IUUC-Ttr-128695	Tursiops truncatus	83.48	0.00e+00	749.00
IUUC-Uma-129638	Ustilago maydis	51.28	3.00e-118	418.00
IUUC-Vda-129963	Verticillium dahliae	51.96	8.00e-115	407.00
IUUC-Vpa-130637	Vicugna pacos	92.08	0.00e+00	828.00
IUUC-Vvi-131613	Vitis vinifera	48.46	1.00e-84	306.00
IUUC-Xtr-132924	Xenopus tropicalis	89.49	0.00e+00	819.00
IUUC-Xma-133356	Xiphophorus maculatus	85.34	0.00e+00	793.00
IUUC-Yli-134365	Yarrowia lipolytica	52.17	7.00e-111	394.00
IUUC-Zma-135941	Zea mays	44.90	2.00e-85	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence