iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062655

UUCD1 version

UUC-MoD-00254

Ensembl Protein ID

ENSMODP00000005762.3

UniProt Accession

F6U6J8; F6U6J8_MONDO

Protein Name

Uncharacterized protein

Gene Name

RAD18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004679.3	ENSMODT00000005883.3	ENSMODP00000005762.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.39	1.00e-126	451.00	IUUC-Hsa-045957
UBD/ZnF/UBZ	60.39	1.00e-126	451.00	IUUC-Hsa-045957
UBD/ZnF/UBZ	65.23	1.00e-121	434.00	IUUC-Mmu-063647
E3 activity/RING/RING	37.33	5.00e-12	67.40	IUUC-Sce-106454
UBD/ZnF/UBZ	37.33	5.00e-12	67.40	IUUC-Sce-106454
E3 activity/RING/RING	25.70	1.00e-19	92.80	IUUC-Spo-108248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAQLEEDQWP SRLVKMKAVD DLLRCGICFD YFNIAMIIPQ CSHNYCSLCI RKFLSYKTQC 60
PTCCVTVTEP DLKNNRILDE LVKSFSAARN HLLQYTLDSP PISPLSSSIK NISGKIHIPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCTTCAC TTGCCCGGGA CTACAACTCC CAGCAACGCC TGCGCCCAAC AGGTGCCGGA 60
TGAATGACGG AGCGGTAGTG ACGTAAACCG AGGGCGGGTA ATTTCGACTG GCGGGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR006642--Znf_Rad18_put
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50800--SAP
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02037--SAP

SMART

SM00184--RING
SM00513--SAP
SM00734--ZnF_Rad18

Gene Ontology

GO:0005813--C:centrosome
GO:0016604--C:nuclear body
GO:0042405--C:nuclear inclusion body
GO:0005634--C:nucleus
GO:0097505--C:Rad6-Rad18 complex
GO:0005657--C:replication fork
GO:0035861--C:site of double-strand break
GO:0043142--F:single-stranded DNA-dependent ATPase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0000403--F:Y-form DNA binding
GO:0008270--F:zinc ion binding
GO:0060548--P:negative regulation of cell death
GO:0051984--P:positive regulation of chromosome segregation
GO:0006301--P:postreplication repair
GO:0051865--P:protein autoubiquitination
GO:0006513--P:protein monoubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002086	Ailuropoda melanoleuca	52.23	3.00e-127	449.00
IUUC-Apl-003657	Anas platyrhynchos	58.70	5.00e-108	384.00
IUUC-Aca-005369	Anolis carolinensis	70.83	2.00e-57	214.00
IUUC-Ago-007876	Ashbya gossypii	23.89	2.00e-15	76.60
IUUC-Acl-008246	Aspergillus clavatus	27.56	3.00e-29	122.00
IUUC-Afl-008666	Aspergillus flavus	29.20	9.00e-17	81.30
IUUC-Afu-009052	Aspergillus fumigatus	27.90	1.00e-27	117.00
IUUC-Ani-009488	Aspergillus nidulans	25.17	4.00e-30	125.00
IUUC-Ang-009681	Aspergillus niger	27.81	1.00e-15	77.80
IUUC-Aor-010037	Aspergillus oryzae	25.90	3.00e-28	119.00
IUUC-Ate-010516	Aspergillus terreus	38.55	2.00e-12	65.90
IUUC-Ame-010630	Astyanax mexicanus	41.19	1.00e-73	270.00
IUUC-Bgr-012178	Blumeria graminis	27.39	1.00e-30	127.00
IUUC-Bta-012976	Bos taurus	53.00	2.00e-109	389.00
IUUC-Bci-013680	Botrytis cinerea	44.05	4.00e-16	79.30
IUUC-Cja-019453	Callithrix jacchus	56.74	2.00e-133	469.00
IUUC-Cfa-020856	Canis familiaris	57.89	2.00e-135	475.00
IUUC-Cpo-021950	Cavia porcellus	55.45	4.00e-127	447.00
IUUC-Csa-023997	Chlorocebus sabaeus	59.15	2.00e-126	445.00
IUUC-Cho-024771	Choloepus hoffmanni	62.44	9.00e-65	241.00
IUUC-Cgl-026668	Colletotrichum gloeosporioides	26.74	2.00e-17	84.00
IUUC-Cme-027202	Cyanidioschyzon merolae	31.46	2.00e-12	67.00
IUUC-Dre-028479	Danio rerio	44.63	7.00e-73	267.00
IUUC-Dno-028943	Dasypus novemcinctus	57.93	7.00e-122	430.00
IUUC-Dor-031046	Dipodomys ordii	51.90	1.00e-89	323.00
IUUC-Dse-031235	Dothistroma septosporum	28.21	3.00e-13	70.10
IUUC-Ete-032503	Echinops telfairi	58.17	2.00e-82	299.00
IUUC-Eca-033725	Equus caballus	58.89	1.00e-130	459.00
IUUC-Eeu-034573	Erinaceus europaeus	58.23	5.00e-92	331.00
IUUC-Fca-036495	Felis catus	57.93	7.00e-128	450.00
IUUC-Fal-036791	Ficedula albicollis	52.78	4.00e-95	342.00
IUUC-Fox-037868	Fusarium oxysporum	40.24	7.00e-14	71.60
IUUC-Fso-038144	Fusarium solani	30.49	3.00e-17	82.80
IUUC-Gmo-039152	Gadus morhua	46.49	3.00e-66	245.00
IUUC-Ggr-039737	Gaeumannomyces graminis	24.42	4.00e-14	72.80
IUUC-Gga-040788	Gallus gallus	59.54	4.00e-111	395.00
IUUC-Gac-041993	Gasterosteus aculeatus	42.42	5.00e-78	284.00
IUUC-Ggo-044889	Gorilla gorilla	59.56	6.00e-128	451.00
IUUC-Hsa-045957	Homo sapiens	59.92	5.00e-130	457.00
IUUC-Itr-048998	Ictidomys tridecemlineatus	59.39	2.00e-135	475.00
IUUC-Kpa-049300	Komagataella pastoris	33.33	1.00e-09	57.40
IUUC-Lch-050172	Latimeria chalumnae	53.69	2.00e-71	262.00
IUUC-Loc-052609	Lepisosteus oculatus	50.27	2.00e-83	302.00
IUUC-Lma-053037	Leptosphaeria maculans	24.18	1.00e-16	81.60
IUUC-Laf-053889	Loxodonta africana	60.91	1.00e-110	393.00
IUUC-Mcc-055853	Macaca mulatta	59.76	2.00e-127	449.00
IUUC-Meu-056866	Macropus eugenii	72.46	5.00e-122	431.00
IUUC-Mor-057071	Magnaporthe oryzae	26.24	7.00e-32	131.00
IUUC-Mpo-057628	Magnaporthe poae	42.86	3.00e-13	69.70
IUUC-Mla-058953	Melampsora laricipopulina	24.30	3.00e-18	86.70
IUUC-Mga-059687	Meleagris gallopavo	59.67	7.00e-106	377.00
IUUC-Mvi-060412	Microbotryum violaceum	26.27	5.00e-11	62.80
IUUC-Mmr-061563	Microcebus murinus	58.13	6.00e-133	467.00
IUUC-Mmu-063647	Mus musculus	65.23	3.00e-115	408.00
IUUC-Mpu-065778	Mustela putorius furo	57.55	4.00e-138	484.00
IUUC-Mlu-068205	Myotis lucifugus	59.60	2.00e-115	409.00
IUUC-Nfi-068501	Neosartorya fischeri	27.20	2.00e-27	116.00
IUUC-Ncr-068917	Neurospora crassa	34.09	5.00e-18	85.90
IUUC-Nle-068990	Nomascus leucogenys	59.23	1.00e-128	453.00
IUUC-Opr-071146	Ochotona princeps	55.78	6.00e-118	417.00
IUUC-Ont-071835	Oreochromis niloticus	45.22	1.00e-76	280.00
IUUC-Oan-072827	Ornithorhynchus anatinus	40.41	2.00e-48	185.00
IUUC-Ocu-073986	Oryctolagus cuniculus	57.40	8.00e-120	423.00
IUUC-Ola-086997	Oryzias latipes	45.10	1.00e-62	233.00
IUUC-Olu-087771	Ostreococcus lucimarinus	34.48	9.00e-12	64.70
IUUC-Oga-088092	Otolemur garnettii	57.84	7.00e-134	470.00
IUUC-Oar-089651	Ovis aries	55.49	3.00e-117	415.00
IUUC-Ptr-091103	Pan troglodytes	59.72	3.00e-129	454.00
IUUC-Pan-092478	Papio anubis	59.64	4.00e-128	451.00
IUUC-Psi-093356	Pelodiscus sinensis	58.29	5.00e-114	404.00
IUUC-Pfo-096663	Poecilia formosa	40.90	7.00e-58	218.00
IUUC-Pab-098515	Pongo abelii	59.92	1.00e-129	456.00
IUUC-Pca-100588	Procavia capensis	45.31	2.00e-81	296.00
IUUC-Pva-102377	Pteropus vampyrus	56.54	3.00e-127	448.00
IUUC-Pgr-103556	Puccinia graminis	21.50	8.00e-13	68.90
IUUC-Pte-104362	Pyrenophora teres	26.02	2.00e-10	60.80
IUUC-Pyt-104823	Pyrenophora triticirepentis	26.72	2.00e-09	57.00
IUUC-Rno-105866	Rattus norvegicus	60.65	6.00e-122	431.00
IUUC-Sce-106454	Saccharomyces cerevisiae	37.33	1.00e-12	67.40
IUUC-Sha-107515	Sarcophilus harrisii	75.92	6.00e-160	556.00
IUUC-Sja-107689	Schizosaccharomyces japonicus	43.06	2.00e-13	70.10
IUUC-Spo-108248	Schizosaccharomyces pombe	38.82	3.00e-14	72.80
IUUC-Ssl-108430	Sclerotinia sclerotiorum	23.84	2.00e-14	73.90
IUUC-Sre-115123	Sporisorium reilianum	25.57	1.00e-12	67.80
IUUC-Ssc-115992	Sus scrofa	58.79	5.00e-99	354.00
IUUC-Tgu-117286	Taeniopygia guttata	53.11	1.00e-102	366.00
IUUC-Tru-117959	Takifugu rubripes	44.24	7.00e-67	247.00
IUUC-Tsy-119286	Tarsius syrichta	44.44	4.00e-81	295.00
IUUC-Tni-120570	Tetraodon nigroviridis	43.84	5.00e-70	257.00
IUUC-Tre-121893	Trichoderma reesei	24.48	1.00e-13	71.20
IUUC-Tvi-122405	Trichoderma virens	41.98	3.00e-14	72.80
IUUC-Tbe-127758	Tupaia belangeri	57.27	1.00e-63	237.00
IUUC-Ttr-128841	Tursiops truncatus	59.88	2.00e-130	459.00
IUUC-Vda-130021	Verticillium dahliae	34.21	4.00e-16	78.20
IUUC-Vpa-130169	Vicugna pacos	55.11	1.00e-104	373.00
IUUC-Xtr-132308	Xenopus tropicalis	55.94	9.00e-106	376.00
IUUC-Xma-133868	Xiphophorus maculatus	42.93	2.00e-65	243.00
IUUC-Yli-134474	Yarrowia lipolytica	31.10	5.00e-15	75.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence