iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027733

Ensembl Protein ID

ENSDARP00000008668.8

UniProt Accession

A3KPR1; A3KPR1_DANRE

Genbank Protein ID

ENSDARP00000008668

Protein Name

WD repeat domain 36

Genbank Nucleotide ID

BX294395

Gene Name

wdr36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000004774.9	ENSDART00000014049.8	ENSDARP00000008668.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-23	81.5	566	603
UBD/Beta-Prp	4.40e-53	181.3	232	526

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + ++++ f +d + l+++s D+ti+ WDl +g l+
   Q: 566  GHRGQINDMTFsPDgRWLITASMDCTIRTWDLPSGSLV 603
           8***********99999***************999765 PP

UBD/Beta-Prp

   S: 9    hksvitcvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvw..dls..tgkcvhtlk 91
           + ++it++ f +++ +++a+gs  g i +wd++++kl++++   h+ +++ ++f +++++l+t + D++i+vw  d+   +g  ++   
   Q: 232  DWGPITALSFrTDGHPIMASGSPIGHIGLWDLEEKKLVSQMrDAHTTAIAGLTFLQNEPLLITNGADNAIRVWifDVAggDGRLLRQRM 320
           55799*****9999***************************999*****************************8877777788888888 PP
   S: 92   ghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrl..Wdl....ktg 169
           gh++  + ++ +  sg  ++s+++d t++ + + ++   ++    tl++ ++   +v+++  +   ++ ++ +t r   Wd      +g
   Q: 321  GHSAPPTKIRHYDqSGLNILSAGQDGTLQSFSTVHERFNKSlghgTLNKAKAKKKGVKYDTAKLPSITTFASETARQsdWDGiiacHRG 409
           ********98777588**************98887777777999*****************997777777777777544888****999 PP
   S: 170  kllrtltgghtdsvyslsfdsng....................kelvsgsldgtvklwdlqtgec...vrtlnghtdnvksvrfspnde 235
           +l++t   ++++s    ++++++                    ++ v +   g + ++++q+g       + ++h+ +v+ v+++  ++
   Q: 410  FLMTTSWNYQKGSMGAHKLEPERfnrnrslnvhatavdisscgNFAVIALSSGHIDVYNMQSGLHrghYGEDKAHEGPVRGVAVDALNQ 498
           99999877799998888855555555559999999999999997777778889********7766333666689*************** PP
   S: 236  rlvsgssDgsiriWdlrsgdllktlqlh 263
           +  s+++D  ++iW  +s++ l+t  l+
   Q: 499  LTFSVGADHLLKIWKFKSKEHLHTHRLP 526
           ********************99998776 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSSMSANKKG SVIFSGFRAL GLYSNHLAHV VRFHKKHREF YVVTAVGQCF HTYNVKKLGI 60
VAVSNALPED ISSVTADCML VYAAYGKLIS AFARSREVVH TYTGHQADVH LLLPFGNHLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAGCGTAG CACTGTTTTG CTACTGTTCT CTGCTGGTAC AGAAATGTGC CTGAAAGTGC 60
AATAAACGTT AACCGGGATT TTGAGCACAG ACAGCGAAGA TTAAGATTGT GCTGGCGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0006364--P:rRNA processing

KEGG

dre:321745

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	36.62	3.00e-145	509.00
IUUC-Aml-002289	Ailuropoda melanoleuca	65.51	0.00e+00	1187.00
IUUC-Atr-002859	Amborella trichopoda	34.08	1.00e-129	457.00
IUUC-Apl-003505	Anas platyrhynchos	67.85	0.00e+00	1129.00
IUUC-Aca-004339	Anolis carolinensis	69.45	0.00e+00	1259.00
IUUC-Aly-005913	Arabidopsis lyrata	35.93	2.00e-152	533.00
IUUC-Ath-006767	Arabidopsis thaliana	36.07	1.00e-154	540.00
IUUC-Ago-007763	Ashbya gossypii	30.81	2.00e-104	374.00
IUUC-Acl-008275	Aspergillus clavatus	31.28	1.00e-76	281.00
IUUC-Afl-008457	Aspergillus flavus	32.46	1.00e-81	297.00
IUUC-Afu-008914	Aspergillus fumigatus	29.48	3.00e-84	306.00
IUUC-Ani-009225	Aspergillus nidulans	31.56	5.00e-89	322.00
IUUC-Aor-010046	Aspergillus oryzae	30.37	6.00e-104	372.00
IUUC-Ate-010337	Aspergillus terreus	29.87	3.00e-99	357.00
IUUC-Ame-010963	Astyanax mexicanus	82.15	0.00e+00	1453.00
IUUC-Bgr-011973	Blumeria graminis	29.50	1.00e-109	391.00
IUUC-Bta-012462	Bos taurus	65.63	0.00e+00	1180.00
IUUC-Bci-013940	Botrytis cinerea	28.53	4.00e-102	366.00
IUUC-Bdi-014725	Brachypodium distachyon	35.81	2.00e-146	513.00
IUUC-Bol-016534	Brassica oleracea	35.03	1.00e-147	517.00
IUUC-Bra-016781	Brassica rapa	34.49	3.00e-145	509.00
IUUC-Cel-018581	Caenorhabditis elegans	29.22	2.00e-99	357.00
IUUC-Cja-019675	Callithrix jacchus	64.48	0.00e+00	1192.00
IUUC-Cfa-020118	Canis familiaris	65.58	0.00e+00	1172.00
IUUC-Cpo-021798	Cavia porcellus	64.63	0.00e+00	1143.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	28.42	3.00e-25	110.00
IUUC-Csa-023547	Chlorocebus sabaeus	65.68	0.00e+00	1171.00
IUUC-Cho-024518	Choloepus hoffmanni	55.59	0.00e+00	875.00
IUUC-Cin-025339	Ciona intestinalis	46.62	0.00e+00	807.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	27.90	6.00e-101	362.00
IUUC-Cne-026859	Cryptococcus neoformans	33.48	2.00e-135	476.00
IUUC-Cme-027173	Cyanidioschyzon merolae	29.08	2.00e-83	304.00
IUUC-Dno-029439	Dasypus novemcinctus	65.37	0.00e+00	1170.00
IUUC-Dor-030329	Dipodomys ordii	65.34	5.00e-168	585.00
IUUC-Dse-031511	Dothistroma septosporum	28.47	2.00e-89	324.00
IUUC-Dme-031694	Drosophila melanogaster	42.89	0.00e+00	712.00
IUUC-Ete-032930	Echinops telfairi	60.48	0.00e+00	954.00
IUUC-Eca-033302	Equus caballus	65.37	0.00e+00	1178.00
IUUC-Eeu-034516	Erinaceus europaeus	64.50	0.00e+00	1210.00
IUUC-Fca-036064	Felis catus	65.26	0.00e+00	1167.00
IUUC-Fal-037024	Ficedula albicollis	66.93	0.00e+00	1229.00
IUUC-Fox-037787	Fusarium oxysporum	26.69	5.00e-85	309.00
IUUC-Fso-038378	Fusarium solani	27.15	4.00e-84	306.00
IUUC-Gmo-039637	Gadus morhua	57.14	1.00e-166	579.00
IUUC-Ggr-040108	Gaeumannomyces graminis	27.15	1.00e-95	345.00
IUUC-Gga-040982	Gallus gallus	67.45	0.00e+00	1251.00
IUUC-Gac-041565	Gasterosteus aculeatus	62.54	0.00e+00	1053.00
IUUC-Gma-043185	Glycine max	35.47	9.00e-152	531.00
IUUC-Ggo-045463	Gorilla gorilla	64.89	0.00e+00	1188.00
IUUC-Hsa-045675	Homo sapiens	64.81	0.00e+00	1192.00
IUUC-Hvu-047352	Hordeum vulgare	35.29	7.00e-131	461.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	65.51	0.00e+00	1196.00
IUUC-Kpa-049164	Komagataella pastoris	31.47	3.00e-101	363.00
IUUC-Lch-050476	Latimeria chalumnae	70.02	0.00e+00	1297.00
IUUC-Lpe-051556	Leersia perrieri	31.17	6.00e-88	318.00
IUUC-Loc-052820	Lepisosteus oculatus	76.60	0.00e+00	1374.00
IUUC-Lma-052961	Leptosphaeria maculans	28.44	2.00e-85	311.00
IUUC-Laf-054006	Loxodonta africana	63.65	0.00e+00	1139.00
IUUC-Mcc-055037	Macaca mulatta	65.03	0.00e+00	1192.00
IUUC-Mor-057280	Magnaporthe oryzae	28.11	3.00e-99	356.00
IUUC-Mpo-057408	Magnaporthe poae	27.10	6.00e-92	332.00
IUUC-Mtr-058473	Medicago truncatula	36.00	1.00e-148	520.00
IUUC-Mla-058892	Melampsora laricipopulina	32.55	3.00e-111	396.00
IUUC-Mga-059598	Meleagris gallopavo	56.28	0.00e+00	924.00
IUUC-Mvi-060334	Microbotryum violaceum	34.90	1.00e-114	408.00
IUUC-Mmr-061239	Microcebus murinus	63.81	0.00e+00	1163.00
IUUC-Mdo-062471	Monodelphis domestica	64.68	0.00e+00	1140.00
IUUC-Mmu-063872	Mus musculus	64.92	0.00e+00	1216.00
IUUC-Mac-064631	Musa acuminata	35.18	9.00e-137	481.00
IUUC-Mpu-066039	Mustela putorius furo	65.14	0.00e+00	1197.00
IUUC-Mlu-067485	Myotis lucifugus	65.00	0.00e+00	1187.00
IUUC-Nfi-068319	Neosartorya fischeri	27.55	5.00e-83	303.00
IUUC-Ncr-068725	Neurospora crassa	27.09	8.00e-91	328.00
IUUC-Nle-069050	Nomascus leucogenys	65.26	0.00e+00	1199.00
IUUC-Opr-070437	Ochotona princeps	59.46	2.00e-100	360.00
IUUC-Ont-071574	Oreochromis niloticus	63.48	0.00e+00	1100.00
IUUC-Oan-072826	Ornithorhynchus anatinus	65.26	0.00e+00	1169.00
IUUC-Ocu-073995	Oryctolagus cuniculus	64.37	0.00e+00	1139.00
IUUC-Oba-075407	Oryza barthii	31.39	6.00e-116	412.00
IUUC-Obr-076451	Oryza brachyantha	35.14	8.00e-149	521.00
IUUC-Ogl-077535	Oryza glaberrima	34.64	1.00e-144	507.00
IUUC-Ogu-077995	Oryza glumaepatula	30.93	1.00e-113	404.00
IUUC-Oin-079431	Oryza indica	34.93	2.00e-147	516.00
IUUC-Olo-080495	Oryza longistaminata	31.27	9.00e-113	401.00
IUUC-Oni-082336	Oryza nivara	33.52	8.00e-136	478.00
IUUC-Opu-084028	Oryza punctata	33.22	4.00e-123	436.00
IUUC-Oru-084500	Oryza rufipogon	31.24	3.00e-114	406.00
IUUC-Osa-086242	Oryza sativa	34.83	4.00e-147	515.00
IUUC-Ola-086612	Oryzias latipes	60.50	0.00e+00	863.00
IUUC-Olu-087703	Ostreococcus lucimarinus	28.53	4.00e-102	366.00
IUUC-Oga-088572	Otolemur garnettii	64.67	0.00e+00	1179.00
IUUC-Oar-090363	Ovis aries	65.59	0.00e+00	1197.00
IUUC-Ptr-090477	Pan troglodytes	65.03	0.00e+00	1179.00
IUUC-Pan-092914	Papio anubis	65.26	0.00e+00	1197.00
IUUC-Psi-093019	Pelodiscus sinensis	70.09	0.00e+00	1291.00
IUUC-Pma-094303	Petromyzon marinus	54.41	0.00e+00	871.00
IUUC-Pno-094938	Phaeosphaeria nodorum	28.02	1.00e-80	295.00
IUUC-Ppa-095720	Physcomitrella patens	34.38	3.00e-145	509.00
IUUC-Pfo-097034	Poecilia formosa	60.36	0.00e+00	1032.00
IUUC-Pab-097669	Pongo abelii	65.03	0.00e+00	1194.00
IUUC-Pop-098835	Populus trichocarpa	35.28	1.00e-150	527.00
IUUC-Pca-101097	Procavia capensis	64.03	7.00e-131	461.00
IUUC-Ppe-101430	Prunus persica	35.37	9.00e-153	534.00
IUUC-Pva-103152	Pteropus vampyrus	65.37	0.00e+00	1206.00
IUUC-Pgr-103517	Puccinia graminis	34.21	7.00e-121	428.00
IUUC-Ptt-103697	Puccinia triticina	33.38	9.00e-100	358.00
IUUC-Pte-104121	Pyrenophora teres	27.98	7.00e-89	322.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	27.98	3.00e-89	323.00
IUUC-Rno-105435	Rattus norvegicus	64.70	0.00e+00	1189.00
IUUC-Sce-106202	Saccharomyces cerevisiae	30.43	3.00e-102	366.00
IUUC-Sha-107272	Sarcophilus harrisii	64.05	0.00e+00	1083.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	34.07	5.00e-140	492.00
IUUC-Spo-108256	Schizosaccharomyces pombe	33.83	1.00e-131	464.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	28.75	2.00e-103	370.00
IUUC-Smo-108762	Selaginella moellendorffii	36.18	2.00e-154	539.00
IUUC-Sit-110051	Setaria italica	34.53	7.00e-144	504.00
IUUC-Sly-111181	Solanum lycopersicum	35.97	8.00e-156	544.00
IUUC-Stu-112018	Solanum tuberosum	35.64	1.00e-153	537.00
IUUC-Sar-113348	Sorex araneus	64.37	0.00e+00	830.00
IUUC-Sbi-114282	Sorghum bicolor	35.89	9.00e-146	511.00
IUUC-Sre-114946	Sporisorium reilianum	31.95	3.00e-87	317.00
IUUC-Ssc-115287	Sus scrofa	65.63	0.00e+00	1199.00
IUUC-Tgu-117138	Taeniopygia guttata	62.87	0.00e+00	1004.00
IUUC-Tru-118232	Takifugu rubripes	62.73	0.00e+00	1080.00
IUUC-Tsy-119502	Tarsius syrichta	53.90	0.00e+00	937.00
IUUC-Tni-120378	Tetraodon nigroviridis	62.90	0.00e+00	1055.00
IUUC-Tca-121506	Theobroma cacao	35.58	3.00e-146	513.00
IUUC-Tre-122166	Trichoderma reesei	26.99	3.00e-94	340.00
IUUC-Tvi-122385	Trichoderma virens	26.97	4.00e-96	346.00
IUUC-Tae-122836	Triticum aestivum	35.99	9.00e-151	527.00
IUUC-Tur-126490	Triticum urartu	33.10	1.00e-114	407.00
IUUC-Tme-127157	Tuber melanosporum	30.29	2.00e-96	347.00
IUUC-Tbe-127981	Tupaia belangeri	60.43	0.00e+00	1018.00
IUUC-Ttr-128886	Tursiops truncatus	64.48	0.00e+00	1172.00
IUUC-Uma-129439	Ustilago maydis	31.60	3.00e-95	343.00
IUUC-Vda-129760	Verticillium dahliae	27.67	2.00e-95	344.00
IUUC-Vpa-130456	Vicugna pacos	65.48	0.00e+00	1190.00
IUUC-Vvi-131086	Vitis vinifera	35.69	1.00e-147	517.00
IUUC-Xtr-131829	Xenopus tropicalis	66.29	0.00e+00	1213.00
IUUC-Xma-133588	Xiphophorus maculatus	60.81	0.00e+00	1019.00
IUUC-Yli-134328	Yarrowia lipolytica	29.12	5.00e-98	352.00
IUUC-Zma-135808	Zea mays	35.17	2.00e-144	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence