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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105899
UUCD1 version UUC-RaN-00142
Ensembl Protein ID ENSRNOP00000074508.1
UniProt Accession A0A0G2K884; A0A0G2K884_RAT
Genbank Protein ID ENSRNOP00000074508
Protein Name LON peptidase N-terminal domain and ring finger 3
Genbank Nucleotide ID AABR07041226
Gene Name Lonrf3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000013092.7 ENSRNOT00000089266.1 ENSRNOP00000074508.1
ENSRNOG00000013092.7 ENSRNOT00000017550.4 ENSRNOP00000017550.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 4.20e-10 40.0 514 582
E3 activity/RING/RING 4.60e-07 30.6 517 555
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpl....teedlvPnltlrrliqawce 70
           ++ C++ + l+ +Pv++p+G+t+  +++e++l+++ k cP+++  l     +++   n  + +li +++ 
   Q: 514  DLECSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNAK-CPLCKDVLlqclPSRKYSKNVIMEELIAKFLP 582
           678*********************************9.****9877555588888999999999988875 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f + p+++pCgH+f+++Cl++          +++CPlC+
   Q: 517  CSLCMRLFYE-PVTTPCGHTFCLKCLERC------LDHNAKCPLCK 555
           ****999977.***************999......9*********7 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MDSLQTAQMV SLSAELGSNN LELAEPEEPA ASMAVGESAA HSEKVTPEGS QPPGAQEPEQ 60
SQPLAASTPP ECKVLLTQAD ALASRGHLRE ALEVYRQLSE RQQLVAEQLE QLVRCLADSI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105899|E3,U-box;E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGCAGCCG GCATGGAGCT CGGGAGGCGA GGCAGACTCG CGCGCGCGGC GATCCCGCCT 60
TCTCGTCAGC GCAGCCCGCT TCCAGCCGCC GCTCTTTCCT GCTAGTTCCC TGTTCCTAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105899|E3,U-box;E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51787--LON_N
PS50005--TPR
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX
SMART

SM00464--LON
SM00184--RING
SM00028--TPR
Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000755 Aegilops tauschii 28.42 9.00e-11 61.60
IUUC-Aml-001774 Ailuropoda melanoleuca 68.69 0.00e+00 954.00
IUUC-Apl-003916 Anas platyrhynchos 74.78 1.00e-157 549.00
IUUC-Ame-010881 Astyanax mexicanus 48.50 6.00e-178 617.00
IUUC-Bta-012872 Bos taurus 76.25 0.00e+00 1085.00
IUUC-Cja-018747 Callithrix jacchus 69.38 0.00e+00 927.00
IUUC-Cfa-020101 Canis familiaris 74.36 0.00e+00 1047.00
IUUC-Cpo-022041 Cavia porcellus 67.76 0.00e+00 962.00
IUUC-Csa-024034 Chlorocebus sabaeus 76.23 0.00e+00 1097.00
IUUC-Cin-025668 Ciona intestinalis 33.89 1.00e-101 363.00
IUUC-Csv-026364 Ciona savignyi 45.54 3.00e-78 285.00
IUUC-Dno-029518 Dasypus novemcinctus 79.97 0.00e+00 1113.00
IUUC-Dor-031132 Dipodomys ordii 65.71 0.00e+00 986.00
IUUC-Dse-031331 Dothistroma septosporum 30.06 9.00e-37 147.00
IUUC-Eca-033382 Equus caballus 78.06 0.00e+00 1132.00
IUUC-Fca-035777 Felis catus 85.57 0.00e+00 834.00
IUUC-Fal-036730 Ficedula albicollis 64.93 0.00e+00 709.00
IUUC-Gga-041187 Gallus gallus 60.31 0.00e+00 877.00
IUUC-Gac-042201 Gasterosteus aculeatus 42.65 2.00e-154 539.00
IUUC-Ggo-045111 Gorilla gorilla 76.23 0.00e+00 1098.00
IUUC-Hsa-045695 Homo sapiens 76.23 0.00e+00 1096.00
IUUC-Lch-050429 Latimeria chalumnae 54.59 0.00e+00 773.00
IUUC-Loc-051823 Lepisosteus oculatus 52.34 0.00e+00 677.00
IUUC-Lma-053145 Leptosphaeria maculans 31.25 1.00e-39 157.00
IUUC-Laf-053434 Loxodonta africana 76.01 0.00e+00 843.00
IUUC-Mcc-055249 Macaca mulatta 85.49 0.00e+00 840.00
IUUC-Mga-060131 Meleagris gallopavo 62.91 0.00e+00 660.00
IUUC-Mmr-060749 Microcebus murinus 77.87 0.00e+00 1131.00
IUUC-Mdo-062261 Monodelphis domestica 53.13 0.00e+00 738.00
IUUC-Mmu-063219 Mus musculus 86.77 0.00e+00 1239.00
IUUC-Mpu-066222 Mustela putorius furo 69.02 0.00e+00 945.00
IUUC-Mlu-067769 Myotis lucifugus 71.73 0.00e+00 1032.00
IUUC-Nle-069738 Nomascus leucogenys 78.72 0.00e+00 909.00
IUUC-Ont-072029 Oreochromis niloticus 47.73 3.00e-177 615.00
IUUC-Oan-073179 Ornithorhynchus anatinus 67.24 0.00e+00 675.00
IUUC-Ocu-074884 Oryctolagus cuniculus 73.99 0.00e+00 1014.00
IUUC-Ogl-077658 Oryza glaberrima 31.91 2.00e-11 63.20
IUUC-Ome-081482 Oryza meridionalis 31.91 3.00e-11 62.80
IUUC-Osa-085978 Oryza sativa 31.91 2.00e-11 63.20
IUUC-Ola-086698 Oryzias latipes 49.05 0.00e+00 629.00
IUUC-Oga-089109 Otolemur garnettii 74.88 0.00e+00 1068.00
IUUC-Oar-089903 Ovis aries 76.25 0.00e+00 1096.00
IUUC-Ptr-091238 Pan troglodytes 75.55 0.00e+00 1083.00
IUUC-Pan-092379 Papio anubis 81.86 0.00e+00 1221.00
IUUC-Psi-093418 Pelodiscus sinensis 71.39 6.00e-161 560.00
IUUC-Pma-094231 Petromyzon marinus 62.87 8.00e-109 386.00
IUUC-Pno-094889 Phaeosphaeria nodorum 39.15 9.00e-41 160.00
IUUC-Pfo-097284 Poecilia formosa 47.70 0.00e+00 627.00
IUUC-Pab-098343 Pongo abelii 81.62 0.00e+00 1209.00
IUUC-Pca-100905 Procavia capensis 71.89 0.00e+00 927.00
IUUC-Pva-102242 Pteropus vampyrus 72.69 0.00e+00 1014.00
IUUC-Ptt-103898 Puccinia triticina 27.07 2.00e-29 124.00
IUUC-Pte-104214 Pyrenophora teres 30.75 7.00e-38 151.00
IUUC-Pyt-104565 Pyrenophora triticirepentis 31.04 8.00e-38 151.00
IUUC-Sha-107565 Sarcophilus harrisii 49.73 0.00e+00 669.00
IUUC-Sja-107742 Schizosaccharomyces japonicus 37.80 1.00e-31 130.00
IUUC-Sar-112999 Sorex araneus 63.46 8.00e-128 450.00
IUUC-Ssc-115705 Sus scrofa 77.89 0.00e+00 1108.00
IUUC-Tgu-116978 Taeniopygia guttata 60.45 0.00e+00 777.00
IUUC-Tsy-118988 Tarsius syrichta 80.07 0.00e+00 877.00
IUUC-Tbe-127563 Tupaia belangeri 67.00 4.00e-138 484.00
IUUC-Ttr-128875 Tursiops truncatus 75.58 0.00e+00 1037.00
IUUC-Vpa-130779 Vicugna pacos 94.77 9.00e-159 553.00
IUUC-Xtr-132508 Xenopus tropicalis 49.46 0.00e+00 684.00
Created Date 25-Jun-2017

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