iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068335

Ensembl Protein ID

CADNFIAP00001129

UniProt Accession

A1D3M5; A1D3M5_NEOFI

Genbank Protein ID

EAW23018.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase, putative

Genbank Nucleotide ID

DS027688

Gene Name

NFIA_017190

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00001168	CADNFIAT00001168	CADNFIAP00001129

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-31	108.8	41	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 4    kNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalk.....keaeefsgye 88
           +N  N CY N++L   +++p++ + + +   +++++     +  +++++l ++f + w   +++    + ++l++ l+     ++  + +  +
   Q: 41   NNGLNLCYRNAALTLFLHTPQFLSWCENYWGQSTSN-----SVPDVVRKLYDMFIAYWqcpNRR--EQAMQSLWTELQspkygQLCWQTTLGQ 126
           4668************************55555544.....4569*************855444..44444555555411011445566699* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgke 180
           q+D+ E+l+ +++ l+++                             + +++ + dl+ + l+ + +c++c+++  +  +   +l+ ++pg++
   Q: 127  QHDTFEMLENIISLLQRHT---------------------------SQPYNDELMDLMTVALSGSRVCKTCKQKDsTVGDRVRYLNADLPGSK 192
           *****************99...........................3455566789****************99846668889********** PP
   S: 181  etkkeslqdcLesftkeeelegenkyycekckkkqe.aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekq 272
           +   + +++++ s +k e+l       c++c  kq   e ++++   +e+Li++++R+      k + k+++++e+  eL +   + +++ k 
   Q: 193  KA--TPIEEAIISGMKSETLA-----DCKTCATKQSpHELQTQIVFPSEILIVQINRY------KESGKLKDEIEVRGELVIPDSLLDDSVKG 272
           65..79**************8.....5****999985677888999999*********......44568888888888887777666666666 PP
   S: 273  kekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevk..eeevleetg..staYvlfYkr 337
           + k  YeL+av+ H G  ++sGHY+a vk  +g+W+  +D++Vt ++  e+++ +  +  ++aY+l Y+r
   Q: 273  QGKIGYELYAVIFHIGdDSKSGHYTAAVKGPSGEWVMTNDNRVTFTQtlEKSMSSPDAgkENAYILAYRR 342
           679*****************************************9973345555544499********98 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MANQPTPPSG SLPSQKKSAV SAAWKHVSLK PTLPTRGFEN NNGLNLCYRN AALTLFLHTP 60
QFLSWCENYW GQSTSNSVPD VVRKLYDMFI AYWQCPNRRE QAMQSLWTEL QSPKYGQLCW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAATC AGCCCACGCC CCCTTCAGGC TCTCTTCCTG TAAGTCCTTC TCTAACATAC 60
ATGATATTAC GGTTAACTGA TTTAACACAA GTCCCAGAAG AAAAGCGCTG TATCCGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nfi:NFIA_017190

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008292	Aspergillus clavatus	42.29	4.00e-88	316.00
IUUC-Afu-009073	Aspergillus fumigatus	88.16	0.00e+00	642.00
IUUC-Ani-009316	Aspergillus nidulans	26.89	3.00e-20	91.70
IUUC-Ang-009871	Aspergillus niger	26.48	2.00e-41	162.00
IUUC-Ate-010392	Aspergillus terreus	30.80	3.00e-51	194.00
IUUC-Bgr-012076	Blumeria graminis	25.57	5.00e-16	76.30
IUUC-Bci-013747	Botrytis cinerea	23.92	8.00e-15	73.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence