iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052348

Ensembl Protein ID

ENSLOCP00000010401.1

UniProt Accession

W5MPU2; W5MPU2_LEPOC

Genbank Protein ID

ENSLOCP00000010401

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01015388

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000008551.1	ENSLOCT00000010415.1	ENSLOCP00000010401.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-61	201.8	479	512
UBD/Beta-Prp	9.50e-103	343.6	230	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtcl+f+ ++++++sdDgt+k+WDl+tg  
   Q: 479  HQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 512
           9*********449******************976 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           k+lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++ ++  i+++gs+Drt+kvw+ +tg+c+htl 
   Q: 230  KVLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLY 314
           6799************..*******************************************..************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+++v+++++++  +++vsGs+d t+rvwd+etgqcl+ +l gh ++v+cv++++  + +vsG++D +v++Wd +t+++l+tl+g ht
   Q: 315  GHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLH-VLMGHVAAVRCVQYDG--RRVVSGAYDFMVKVWDPETETCLHTLQG-HT 397
           *************..************************.****************..***************************9.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++vysl+fd    ++vsgsld+++++wd++tg+c++tl+gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq+++++ ++
   Q: 398  NRVYSLQFDG--IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSA 482
           *********9..9**************************************..************************************ PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
           v++l+f++n +++ s+d++v++w+lk+ e+
   Q: 483  VTCLQFNKNFVITSSDDGTVKLWDLKTGEF 512
           *************************98776 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

AVKKHHRIIT MGFYGTLKMI FYKMKRKLDH GPEVRSFPSG KKPCKGSEYP SPTGLVPYPA 60
TPTTFGDLRA ANGQGQQRRR ITSIQPPTGL QEWLRTFQSW SGPEKLLALD ELIDSCEPTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACGACTGA ATAAGCTTTA GATAACGCAG CGGATACAGA AGACAGACCG TCTTGTGAAA 60
ATTCCACCTG CCCAGTGATG AGGAAAGGAA AGAGGACCGA GGGGGGTAGC TTGGGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0001525--P:angiogenesis
GO:0031642--P:negative regulation of myelination
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0032006--P:regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	96.86	0.00e+00	1068.00
IUUC-Apl-003489	Anas platyrhynchos	95.83	0.00e+00	1070.00
IUUC-Aca-005318	Anolis carolinensis	97.29	0.00e+00	1095.00
IUUC-Ago-007794	Ashbya gossypii	31.48	2.00e-62	233.00
IUUC-Acl-008123	Aspergillus clavatus	32.60	7.00e-75	275.00
IUUC-Afl-008730	Aspergillus flavus	31.33	3.00e-73	270.00
IUUC-Afu-009014	Aspergillus fumigatus	32.93	5.00e-75	275.00
IUUC-Ani-009332	Aspergillus nidulans	33.40	2.00e-79	290.00
IUUC-Ang-009790	Aspergillus niger	31.37	1.00e-75	277.00
IUUC-Aor-010215	Aspergillus oryzae	30.91	1.00e-74	274.00
IUUC-Ate-010535	Aspergillus terreus	32.28	5.00e-76	278.00
IUUC-Ame-010898	Astyanax mexicanus	95.50	0.00e+00	1071.00
IUUC-Bgr-012075	Blumeria graminis	33.47	6.00e-79	288.00
IUUC-Bta-012391	Bos taurus	97.29	0.00e+00	1095.00
IUUC-Bci-013725	Botrytis cinerea	32.48	5.00e-75	275.00
IUUC-Cel-018495	Caenorhabditis elegans	48.53	2.00e-130	459.00
IUUC-Cja-018902	Callithrix jacchus	96.01	0.00e+00	1071.00
IUUC-Cfa-020237	Canis familiaris	96.01	0.00e+00	1070.00
IUUC-Cpo-022234	Cavia porcellus	97.29	0.00e+00	1096.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	35.74	6.00e-49	188.00
IUUC-Csa-023532	Chlorocebus sabaeus	97.23	0.00e+00	1071.00
IUUC-Cho-025026	Choloepus hoffmanni	79.44	0.00e+00	707.00
IUUC-Cin-025516	Ciona intestinalis	70.99	2.00e-140	491.00
IUUC-Csv-026312	Ciona savignyi	67.74	0.00e+00	752.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	35.02	2.00e-85	310.00
IUUC-Cne-027018	Cryptococcus neoformans	33.08	7.00e-73	268.00
IUUC-Cme-027168	Cyanidioschyzon merolae	31.10	2.00e-30	127.00
IUUC-Dre-028303	Danio rerio	95.56	0.00e+00	1058.00
IUUC-Dno-029576	Dasypus novemcinctus	94.52	0.00e+00	1053.00
IUUC-Dor-030196	Dipodomys ordii	94.92	0.00e+00	1054.00
IUUC-Dse-031558	Dothistroma septosporum	38.98	8.00e-70	258.00
IUUC-Dme-031702	Drosophila melanogaster	73.32	0.00e+00	797.00
IUUC-Ete-032791	Echinops telfairi	89.26	0.00e+00	981.00
IUUC-Eca-033424	Equus caballus	97.29	0.00e+00	1095.00
IUUC-Eeu-034996	Erinaceus europaeus	94.09	0.00e+00	1033.00
IUUC-Fca-036422	Felis catus	97.23	0.00e+00	1072.00
IUUC-Fal-037267	Ficedula albicollis	95.61	0.00e+00	1062.00
IUUC-Fox-037800	Fusarium oxysporum	34.07	5.00e-84	305.00
IUUC-Fso-038258	Fusarium solani	34.21	1.00e-83	303.00
IUUC-Gmo-039119	Gadus morhua	86.25	0.00e+00	952.00
IUUC-Ggr-039781	Gaeumannomyces graminis	34.86	2.00e-84	306.00
IUUC-Gga-040667	Gallus gallus	96.52	0.00e+00	1072.00
IUUC-Gac-042423	Gasterosteus aculeatus	76.91	0.00e+00	842.00
IUUC-Ggo-044422	Gorilla gorilla	97.23	0.00e+00	1071.00
IUUC-Hsa-045898	Homo sapiens	97.23	0.00e+00	1071.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	99.36	0.00e+00	960.00
IUUC-Kpa-049097	Komagataella pastoris	32.06	2.00e-75	276.00
IUUC-Lch-050414	Latimeria chalumnae	97.41	0.00e+00	1074.00
IUUC-Lma-053185	Leptosphaeria maculans	33.00	4.00e-73	269.00
IUUC-Laf-054054	Loxodonta africana	97.04	0.00e+00	1070.00
IUUC-Mcc-055056	Macaca mulatta	97.23	0.00e+00	1071.00
IUUC-Meu-056778	Macropus eugenii	92.43	5.00e-172	597.00
IUUC-Mor-057133	Magnaporthe oryzae	39.13	7.00e-73	269.00
IUUC-Mpo-057423	Magnaporthe poae	40.06	2.00e-71	263.00
IUUC-Mla-059081	Melampsora laricipopulina	33.52	2.00e-76	280.00
IUUC-Mga-059255	Meleagris gallopavo	97.04	0.00e+00	1071.00
IUUC-Mvi-060490	Microbotryum violaceum	38.75	5.00e-66	246.00
IUUC-Mmr-061292	Microcebus murinus	96.01	0.00e+00	1070.00
IUUC-Mdo-062304	Monodelphis domestica	96.86	0.00e+00	1075.00
IUUC-Mmu-063610	Mus musculus	95.64	0.00e+00	1071.00
IUUC-Mpu-065931	Mustela putorius furo	97.23	0.00e+00	1070.00
IUUC-Mlu-066976	Myotis lucifugus	95.83	0.00e+00	1073.00
IUUC-Nfi-068428	Neosartorya fischeri	31.93	6.00e-75	275.00
IUUC-Ncr-068688	Neurospora crassa	36.17	2.00e-87	317.00
IUUC-Nle-070174	Nomascus leucogenys	97.23	0.00e+00	1071.00
IUUC-Opr-070851	Ochotona princeps	82.89	6.00e-180	623.00
IUUC-Ont-071997	Oreochromis niloticus	96.75	0.00e+00	1118.00
IUUC-Oan-072936	Ornithorhynchus anatinus	96.34	0.00e+00	1071.00
IUUC-Ocu-074742	Oryctolagus cuniculus	96.01	0.00e+00	1073.00
IUUC-Obr-076806	Oryza brachyantha	31.52	1.00e-29	125.00
IUUC-Oin-079809	Oryza indica	31.52	1.00e-29	125.00
IUUC-Ola-087098	Oryzias latipes	95.41	0.00e+00	1080.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.85	9.00e-39	153.00
IUUC-Oga-088884	Otolemur garnettii	99.21	0.00e+00	773.00
IUUC-Oar-090220	Ovis aries	96.51	0.00e+00	1066.00
IUUC-Ptr-090492	Pan troglodytes	97.23	0.00e+00	1071.00
IUUC-Pan-091770	Papio anubis	97.23	0.00e+00	1071.00
IUUC-Psi-093207	Pelodiscus sinensis	97.29	0.00e+00	1096.00
IUUC-Pma-094749	Petromyzon marinus	84.56	0.00e+00	972.00
IUUC-Pno-095026	Phaeosphaeria nodorum	38.83	2.00e-70	260.00
IUUC-Pfo-096493	Poecilia formosa	97.78	0.00e+00	1078.00
IUUC-Pab-098141	Pongo abelii	97.29	0.00e+00	1095.00
IUUC-Pca-100571	Procavia capensis	96.07	0.00e+00	751.00
IUUC-Pva-102988	Pteropus vampyrus	96.18	0.00e+00	1071.00
IUUC-Pgr-103612	Puccinia graminis	35.41	2.00e-61	230.00
IUUC-Pte-104275	Pyrenophora teres	32.18	1.00e-73	271.00
IUUC-Pyt-104438	Pyrenophora triticirepentis	31.93	1.00e-72	267.00
IUUC-Rno-105706	Rattus norvegicus	95.46	0.00e+00	1070.00
IUUC-Sce-106314	Saccharomyces cerevisiae	29.59	3.00e-61	229.00
IUUC-Sha-107653	Sarcophilus harrisii	96.16	0.00e+00	1071.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	33.64	2.00e-78	287.00
IUUC-Spo-108115	Schizosaccharomyces pombe	32.29	2.00e-62	233.00
IUUC-Sar-113600	Sorex araneus	89.84	0.00e+00	984.00
IUUC-Sre-114901	Sporisorium reilianum	48.13	6.00e-67	249.00
IUUC-Ssc-115787	Sus scrofa	94.19	0.00e+00	1042.00
IUUC-Tgu-117510	Taeniopygia guttata	96.34	0.00e+00	1069.00
IUUC-Tru-117819	Takifugu rubripes	97.04	0.00e+00	1097.00
IUUC-Tsy-118828	Tarsius syrichta	96.01	0.00e+00	1070.00
IUUC-Tni-120468	Tetraodon nigroviridis	95.72	0.00e+00	1116.00
IUUC-Tre-122193	Trichoderma reesei	36.19	4.00e-85	308.00
IUUC-Tvi-122615	Trichoderma virens	34.83	1.00e-83	303.00
IUUC-Tme-127021	Tuber melanosporum	35.50	7.00e-84	305.00
IUUC-Tbe-127925	Tupaia belangeri	97.22	0.00e+00	1069.00
IUUC-Ttr-128899	Tursiops truncatus	95.64	0.00e+00	1068.00
IUUC-Uma-129449	Ustilago maydis	46.89	4.00e-66	246.00
IUUC-Vda-129802	Verticillium dahliae	36.61	2.00e-87	316.00
IUUC-Vpa-130082	Vicugna pacos	95.45	0.00e+00	893.00
IUUC-Xtr-132213	Xenopus tropicalis	96.49	0.00e+00	1068.00
IUUC-Xma-133646	Xiphophorus maculatus	97.65	0.00e+00	1099.00
IUUC-Yli-134429	Yarrowia lipolytica	34.68	6.00e-87	314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence