iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cre-022993

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Spliceosome component, nuclear pre-mRNA splicing factor

Genbank Nucleotide ID

DS496114

Gene Name

PRP19; CHLREDRAFT_196941

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CHLREDRAFT_196941	EDP06795	EDP06795

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-22	77.6	386	417
E3 activity/RING/U-box	1.90e-12	46.6	2	60
UBD/Beta-Prp	1.60e-43	148.6	347	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           gH++ +++laf  ++ +++s+sdD  ik+WDlr
   Q: 386  GHAGAIRSLAFseNGYHMASASDD-CIKLWDLR 417
           8**********976699*****99.8*****97 PP

E3 activity/RING/U-box

   S: 7    lCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
            C+Is++++++ vv+  sG+ +++s Iek++++ gk cPvt++pl+ edl P ++ + + 
   Q: 2    FCSISGTVPEQGVVSTkSGHLFEKSLIEKYVRETGK-CPVTGEPLSTEDLLPLKVNKTVK 60
           6*************999*******************.***************99988876 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.ghedsvlslsfspsgdklv 110
           ++ tc++f+pd+ +l tg + + i++w+v+ +k+++  +gh ++++++ fs++g + + +++D+ ik+wdl++   + t++   +   ++++f+ sg++lv
   Q: 347  EPYTCLQFHPDGLILGTGTEGKAIRIWEVKAQKAVAACEGHAGAIRSLAFSENG-YHMASASDDCIKLWDLRKLANFKTIEpYTDGPCTTVAFDHSGQYLV 446
           688**************************************************9.**************999777777777555889999*********** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlk 167
           +G+   +++++  ++++   +tls+  +  + +++ pd++ +  G++D  +r+++++
   Q: 447  VGG--PVVKIYGQKQQWAELKTLSEVPKRASALRWGPDARSVLVGAADHNLRVFSSP 501
           ***..9***********9999*********************************876 PP

Organism

Chlamydomonas reinhardtii

Protein Sequence
(Fasta)

MFCSISGTVP EQGVVSTKSG HLFEKSLIEK YVRETGKCPV TGEPLSTEDL LPLKVNKTVK 60
PRTAPATSIP GLLSLFHDEW DANMLELHNT RTQLHQTRQE LSHALYQHDA ATRVIARLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTAGCATT AGTGAAAGGA ACACTCCTGC TTTGTAACAG CAGCAGGGCC CCGACAAAAC 60
AGGGCCGGTG CACTGGACCT GCAACGCTAG ACCTAATTGC ATTCACGACT TTCATACGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0000974--C:Prp19 complex
GO:0071006--C:U2-type catalytic step 1 spliceosome
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000349--P:generation of catalytic spliceosome for first transesterification step

KEGG

cre:CHLREDRAFT_196941

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	44.25	1.00e-113	403.00
IUUC-Aml-001230	Ailuropoda melanoleuca	40.48	6.00e-93	332.00
IUUC-Atr-002594	Amborella trichopoda	48.20	2.00e-133	467.00
IUUC-Apl-003686	Anas platyrhynchos	37.59	9.00e-65	238.00
IUUC-Aca-005272	Anolis carolinensis	40.27	5.00e-96	342.00
IUUC-Aly-005586	Arabidopsis lyrata	45.26	2.00e-125	440.00
IUUC-Ath-007696	Arabidopsis thaliana	45.65	3.00e-129	453.00
IUUC-Ago-007879	Ashbya gossypii	42.25	9.00e-23	99.80
IUUC-Acl-008335	Aspergillus clavatus	35.01	9.00e-62	229.00
IUUC-Afl-008527	Aspergillus flavus	35.05	4.00e-66	243.00
IUUC-Afu-008957	Aspergillus fumigatus	35.63	6.00e-70	256.00
IUUC-Ani-009280	Aspergillus nidulans	36.09	8.00e-69	252.00
IUUC-Ang-009746	Aspergillus niger	36.20	2.00e-67	247.00
IUUC-Aor-009905	Aspergillus oryzae	35.84	5.00e-68	249.00
IUUC-Ate-010412	Aspergillus terreus	37.10	5.00e-67	246.00
IUUC-Ame-011561	Astyanax mexicanus	39.84	7.00e-38	149.00
IUUC-Bgr-012283	Blumeria graminis	31.60	2.00e-57	214.00
IUUC-Bta-013242	Bos taurus	40.08	5.00e-96	343.00
IUUC-Bci-013901	Botrytis cinerea	34.45	5.00e-67	246.00
IUUC-Bdi-014277	Brachypodium distachyon	47.00	9.00e-132	461.00
IUUC-Bol-016457	Brassica oleracea	45.84	2.00e-129	454.00
IUUC-Bra-017650	Brassica rapa	46.03	6.00e-129	452.00
IUUC-Cel-018271	Caenorhabditis elegans	37.62	2.00e-92	330.00
IUUC-Cja-019879	Callithrix jacchus	40.19	3.00e-95	340.00
IUUC-Cfa-020175	Canis familiaris	40.08	4.00e-96	343.00
IUUC-Cpo-022379	Cavia porcellus	40.08	5.00e-96	342.00
IUUC-Csa-023500	Chlorocebus sabaeus	40.27	1.00e-96	344.00
IUUC-Cho-025065	Choloepus hoffmanni	35.00	7.00e-39	152.00
IUUC-Cin-025699	Ciona intestinalis	44.03	6.00e-85	306.00
IUUC-Csv-026128	Ciona savignyi	40.66	2.00e-96	343.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	33.27	4.00e-65	239.00
IUUC-Cne-026860	Cryptococcus neoformans	37.84	4.00e-87	313.00
IUUC-Dre-028187	Danio rerio	40.86	9.00e-97	345.00
IUUC-Dno-029453	Dasypus novemcinctus	40.27	2.00e-96	344.00
IUUC-Dor-030150	Dipodomys ordii	35.74	2.00e-27	115.00
IUUC-Dse-031220	Dothistroma septosporum	33.98	4.00e-62	230.00
IUUC-Dme-031906	Drosophila melanogaster	39.49	2.00e-86	311.00
IUUC-Ete-033035	Echinops telfairi	41.45	8.00e-48	182.00
IUUC-Eca-033478	Equus caballus	40.08	9.00e-96	342.00
IUUC-Eeu-034974	Erinaceus europaeus	38.11	3.00e-60	224.00
IUUC-Fca-036194	Felis catus	39.69	2.00e-95	340.00
IUUC-Fal-037417	Ficedula albicollis	40.75	3.00e-96	343.00
IUUC-Fox-037922	Fusarium oxysporum	34.39	2.00e-65	241.00
IUUC-Fso-038256	Fusarium solani	35.64	8.00e-69	252.00
IUUC-Gmo-038713	Gadus morhua	41.26	4.00e-100	356.00
IUUC-Ggr-039854	Gaeumannomyces graminis	35.55	8.00e-61	226.00
IUUC-Gga-041143	Gallus gallus	40.55	2.00e-96	344.00
IUUC-Gac-042129	Gasterosteus aculeatus	40.67	3.00e-98	350.00
IUUC-Gma-043635	Glycine max	46.54	2.00e-133	467.00
IUUC-Ggo-045262	Gorilla gorilla	40.27	1.00e-96	344.00
IUUC-Hsa-046036	Homo sapiens	40.27	1.00e-96	344.00
IUUC-Hvu-047442	Hordeum vulgare	48.09	8.00e-75	271.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	40.16	5.00e-96	343.00
IUUC-Lch-050105	Latimeria chalumnae	40.08	2.00e-94	337.00
IUUC-Lpe-050976	Leersia perrieri	47.97	3.00e-132	463.00
IUUC-Loc-052042	Lepisosteus oculatus	36.38	5.00e-65	239.00
IUUC-Lma-053143	Leptosphaeria maculans	33.86	2.00e-64	239.00
IUUC-Laf-053451	Loxodonta africana	38.98	2.00e-93	334.00
IUUC-Mcc-055786	Macaca mulatta	40.27	1.00e-96	344.00
IUUC-Meu-056161	Macropus eugenii	34.89	2.00e-36	145.00
IUUC-Mor-057215	Magnaporthe oryzae	34.64	2.00e-63	234.00
IUUC-Mpo-057419	Magnaporthe poae	34.31	3.00e-54	204.00
IUUC-Mtr-057756	Medicago truncatula	46.03	7.00e-129	452.00
IUUC-Mla-059085	Melampsora laricipopulina	34.80	2.00e-75	274.00
IUUC-Mga-060158	Meleagris gallopavo	41.23	7.00e-84	302.00
IUUC-Mvi-060441	Microbotryum violaceum	34.48	3.00e-68	251.00
IUUC-Mmr-061085	Microcebus murinus	40.27	1.00e-96	344.00
IUUC-Mdo-061804	Monodelphis domestica	40.08	4.00e-96	343.00
IUUC-Mmu-063608	Mus musculus	38.65	1.00e-92	331.00
IUUC-Mac-064972	Musa acuminata	47.68	1.00e-128	451.00
IUUC-Mpu-065700	Mustela putorius furo	40.08	3.00e-96	343.00
IUUC-Mlu-068223	Myotis lucifugus	38.56	5.00e-92	329.00
IUUC-Nfi-068504	Neosartorya fischeri	36.01	2.00e-70	257.00
IUUC-Ncr-068729	Neurospora crassa	36.03	4.00e-71	260.00
IUUC-Nle-069754	Nomascus leucogenys	40.27	1.00e-96	344.00
IUUC-Opr-070621	Ochotona princeps	41.77	5.00e-92	329.00
IUUC-Ont-071377	Oreochromis niloticus	40.86	6.00e-98	349.00
IUUC-Ocu-074182	Oryctolagus cuniculus	38.69	9.00e-93	332.00
IUUC-Oba-075509	Oryza barthii	47.97	1.00e-133	468.00
IUUC-Obr-076480	Oryza brachyantha	48.55	2.00e-135	473.00
IUUC-Ogl-077052	Oryza glaberrima	47.97	1.00e-133	468.00
IUUC-Ogu-078919	Oryza glumaepatula	48.16	4.00e-133	466.00
IUUC-Oin-079357	Oryza indica	45.84	4.00e-122	429.00
IUUC-Olo-080376	Oryza longistaminata	47.01	4.00e-121	426.00
IUUC-Ome-081973	Oryza meridionalis	47.22	5.00e-121	426.00
IUUC-Oni-082849	Oryza nivara	47.97	6.00e-134	469.00
IUUC-Opu-083243	Oryza punctata	47.78	5.00e-133	466.00
IUUC-Oru-084613	Oryza rufipogon	47.97	1.00e-133	467.00
IUUC-Osa-085407	Oryza sativa	47.97	1.00e-133	468.00
IUUC-Ola-086566	Oryzias latipes	40.27	3.00e-95	340.00
IUUC-Olu-087757	Ostreococcus lucimarinus	44.69	1.00e-113	401.00
IUUC-Oga-089010	Otolemur garnettii	40.00	8.00e-95	338.00
IUUC-Oar-089638	Ovis aries	40.08	5.00e-96	343.00
IUUC-Ptr-091141	Pan troglodytes	40.27	1.00e-96	344.00
IUUC-Pan-092662	Papio anubis	40.27	1.00e-96	344.00
IUUC-Psi-093777	Pelodiscus sinensis	37.83	2.00e-70	257.00
IUUC-Pno-095115	Phaeosphaeria nodorum	32.53	2.00e-64	238.00
IUUC-Ppa-095841	Physcomitrella patens	46.17	3.00e-130	456.00
IUUC-Pfo-096390	Poecilia formosa	40.47	5.00e-98	349.00
IUUC-Pab-098250	Pongo abelii	41.65	1.00e-94	338.00
IUUC-Pop-099854	Populus trichocarpa	47.88	4.00e-135	473.00
IUUC-Pca-100553	Procavia capensis	40.08	2.00e-94	337.00
IUUC-Ppe-101383	Prunus persica	47.21	2.00e-127	447.00
IUUC-Pva-102189	Pteropus vampyrus	40.08	3.00e-96	343.00
IUUC-Pgr-103304	Puccinia graminis	34.48	4.00e-78	283.00
IUUC-Ptt-103984	Puccinia triticina	33.90	7.00e-80	289.00
IUUC-Pte-104385	Pyrenophora teres	32.75	2.00e-68	251.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	33.40	1.00e-68	251.00
IUUC-Rno-105581	Rattus norvegicus	40.08	4.00e-96	343.00
IUUC-Sce-106147	Saccharomyces cerevisiae	42.66	3.00e-25	107.00
IUUC-Sha-107071	Sarcophilus harrisii	38.81	4.00e-93	333.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	28.32	2.00e-39	155.00
IUUC-Spo-108315	Schizosaccharomyces pombe	32.67	7.00e-43	166.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	35.21	2.00e-67	247.00
IUUC-Smo-109648	Selaginella moellendorffii	47.18	4.00e-135	473.00
IUUC-Sit-109873	Setaria italica	48.16	1.00e-132	465.00
IUUC-Sly-111673	Solanum lycopersicum	48.26	1.00e-129	454.00
IUUC-Stu-112125	Solanum tuberosum	47.88	1.00e-128	451.00
IUUC-Sbi-114696	Sorghum bicolor	45.52	3.00e-115	406.00
IUUC-Sre-115134	Sporisorium reilianum	34.19	3.00e-70	257.00
IUUC-Ssc-116260	Sus scrofa	40.08	5.00e-96	343.00
IUUC-Tgu-116533	Taeniopygia guttata	40.94	8.00e-97	345.00
IUUC-Tru-117800	Takifugu rubripes	40.67	4.00e-97	346.00
IUUC-Tsy-118980	Tarsius syrichta	38.31	4.00e-82	296.00
IUUC-Tni-120334	Tetraodon nigroviridis	33.80	3.00e-77	280.00
IUUC-Tca-121807	Theobroma cacao	48.17	5.00e-137	479.00
IUUC-Tre-121920	Trichoderma reesei	33.00	4.00e-61	226.00
IUUC-Tvi-122294	Trichoderma virens	32.41	3.00e-54	204.00
IUUC-Tae-125713	Triticum aestivum	47.97	4.00e-134	469.00
IUUC-Tur-126664	Triticum urartu	43.21	1.00e-123	435.00
IUUC-Tme-127026	Tuber melanosporum	35.56	1.00e-68	251.00
IUUC-Tbe-127582	Tupaia belangeri	38.41	6.00e-61	226.00
IUUC-Ttr-128313	Tursiops truncatus	39.96	7.00e-95	338.00
IUUC-Uma-129626	Ustilago maydis	36.19	1.00e-73	268.00
IUUC-Vda-129699	Verticillium dahliae	34.67	3.00e-66	244.00
IUUC-Vpa-130593	Vicugna pacos	41.51	8.00e-91	325.00
IUUC-Vvi-131668	Vitis vinifera	46.54	5.00e-132	462.00
IUUC-Xtr-132186	Xenopus tropicalis	42.30	5.00e-86	309.00
IUUC-Xma-133212	Xiphophorus maculatus	40.86	2.00e-97	347.00
IUUC-Yli-134607	Yarrowia lipolytica	54.55	2.00e-38	149.00
IUUC-Zma-135662	Zea mays	47.78	3.00e-133	466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence