iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009763

Ensembl Protein ID

CAK96960

UniProt Accession

A2QWV8; A2QWV8_ASPNC

Genbank Protein ID

CAK96960.1

Protein Name

Aspergillus niger contig An11c0240, genomic contig

Genbank Nucleotide ID

AM270241

Gene Name

An11g06630

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An11g06630	CAK96960	CAK96960

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.50e-71	241.0	1437	1797

Active Site

Position(s)	Description	Evidence
1764	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysen........dketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrlldlp 91
            ++leve+ +E g++l G+t+ef++ +ske+ +++l+l++ +e+        +k+ l+p+p s  + +     ++l+lF+ lG++++ ++ d+r++d+ 
   Q: 1437 PSVLEVEYFEEVGTGL-GPTLEFYSTVSKEFSKKKLKLWRENESvhgdeyafGKRGLFPAPMSEEQATsesgkKQLQLFKVLGKFVARSMLDSRIIDIS 1534
           5789************.**********************5555554434555677777777776555499999************************** PP
   S: 92   lsksfyklllgk...klsledleevdpelykslkeikenaes.........................dieelgldltfsvseeilgetkeeeLkpgGen 162
           ++++f++   +      sl  +++vd +l+ksl  +k+ a++                          ++ ++l l f+     l+ + + eL+ +G+n
   Q: 1535 FNPAFFRIAASSssvAPSLGTVKAVDHDLAKSLLLLKSFANAkkavddnrtlskaqktqalqqievgGVKVEDLSLDFT-----LPGYPAIELVKNGSN 1628
           *******998886666899******************887445566666777777777888888888555555555555.....89************* PP
   S: 163  ipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefssee 260
           ipVtneN +             g+++qveafr+Gf++v+p + l+ Ft++el +l     e++++e+l + +k ++g++ ds+ +++++++++e+s ++
   Q: 1629 IPVTNENVD------------LGVQRQVEAFRAGFSQVFPYSALRTFTPQELVMLFGRAeEDWTIETLMDSIKADHGFNMDSRSVRNLLQTMSELSPQQ 1715
           ******965............48999**************************988777689************************************** PP
   S: 261  rkafLqFvTgssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           r++fLqFvTgs++lP+gGf++l p ++v+ +     ++ dd lPs++TC+nyLkLP+Yss ++l+e+L +Ai+e+  +F+ls
   Q: 1716 RRDFLQFVTGSPKLPIGGFKSLTPIFTVVCRpseppYTPDDYLPSVMTCVNYLKLPDYSSLDVLRERLSVAIKEGqGAFHLS 1797
           *************************999988999*99999***********************************8899985 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MSSRITRSAA RVAADSLPST GSGPSPANAA AGSAPNRKRK APARRDRSVD APEQSNPSSS 60
PRKSKRQRRA TSPRAAQSPA TTRRGTRNRP AMSQPGPSSH PAEDSSRNQA SPPASRRKSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTCCA GAATCACTCG CTCCGCCGCG AGAGTAGCTG CAGACTCCCT TCCGTCTACC 60
GGCTCTGGTC CCTCTCCTGC GAACGCGGCC GCTGGTTCGG CTCCAAACCG GAAGCGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	37.31	6.00e-110	391.00
IUUC-Aml-001502	Ailuropoda melanoleuca	39.96	6.00e-112	397.00
IUUC-Atr-002821	Amborella trichopoda	38.81	2.00e-105	376.00
IUUC-Apl-003531	Anas platyrhynchos	38.12	9.00e-104	370.00
IUUC-Aca-004521	Anolis carolinensis	33.86	3.00e-31	130.00
IUUC-Aly-005962	Arabidopsis lyrata	40.83	2.00e-108	386.00
IUUC-Ath-006636	Arabidopsis thaliana	41.18	5.00e-110	391.00
IUUC-Ago-007875	Ashbya gossypii	40.36	3.00e-118	418.00
IUUC-Acl-008242	Aspergillus clavatus	77.99	0.00e+00	2432.00
IUUC-Afl-008736	Aspergillus flavus	80.31	0.00e+00	2507.00
IUUC-Afu-008812	Aspergillus fumigatus	76.58	0.00e+00	2410.00
IUUC-Ani-009407	Aspergillus nidulans	77.76	0.00e+00	1429.00
IUUC-Aor-009941	Aspergillus oryzae	82.62	0.00e+00	1305.00
IUUC-Ate-010459	Aspergillus terreus	77.64	0.00e+00	2357.00
IUUC-Ame-011761	Astyanax mexicanus	41.03	4.00e-116	412.00
IUUC-Bgr-012265	Blumeria graminis	55.16	0.00e+00	1034.00
IUUC-Bta-013070	Bos taurus	40.15	7.00e-112	397.00
IUUC-Bci-013890	Botrytis cinerea	59.72	0.00e+00	1073.00
IUUC-Bdi-014961	Brachypodium distachyon	36.00	1.00e-107	383.00
IUUC-Bol-015942	Brassica oleracea	40.31	6.00e-106	378.00
IUUC-Bra-016849	Brassica rapa	40.31	5.00e-106	378.00
IUUC-Cel-018153	Caenorhabditis elegans	34.32	3.00e-73	270.00
IUUC-Cja-019046	Callithrix jacchus	39.96	8.00e-112	397.00
IUUC-Cfa-020521	Canis familiaris	40.15	2.00e-112	399.00
IUUC-Cpo-021639	Cavia porcellus	39.96	2.00e-111	396.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	36.66	7.00e-81	292.00
IUUC-Csa-023231	Chlorocebus sabaeus	39.96	5.00e-112	398.00
IUUC-Cho-024380	Choloepus hoffmanni	41.79	3.00e-86	312.00
IUUC-Cin-025482	Ciona intestinalis	34.97	1.00e-88	318.00
IUUC-Csv-026121	Ciona savignyi	34.51	8.00e-90	324.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	63.46	0.00e+00	853.00
IUUC-Cne-026857	Cryptococcus neoformans	44.26	5.00e-145	508.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.57	2.00e-73	270.00
IUUC-Dre-028174	Danio rerio	41.47	2.00e-117	416.00
IUUC-Dno-029954	Dasypus novemcinctus	33.86	1.00e-31	132.00
IUUC-Dor-030939	Dipodomys ordii	35.36	1.00e-92	333.00
IUUC-Dse-031444	Dothistroma septosporum	64.83	0.00e+00	881.00
IUUC-Dme-031739	Drosophila melanogaster	31.02	1.00e-73	271.00
IUUC-Ete-032345	Echinops telfairi	33.89	1.00e-80	294.00
IUUC-Eca-033229	Equus caballus	39.96	5.00e-112	398.00
IUUC-Eeu-035205	Erinaceus europaeus	39.78	7.00e-110	391.00
IUUC-Fca-036444	Felis catus	39.96	6.00e-112	398.00
IUUC-Fal-037131	Ficedula albicollis	39.96	6.00e-112	398.00
IUUC-Fox-038035	Fusarium oxysporum	60.33	0.00e+00	812.00
IUUC-Fso-038320	Fusarium solani	60.27	0.00e+00	837.00
IUUC-Gmo-039497	Gadus morhua	41.07	1.00e-114	407.00
IUUC-Ggr-040057	Gaeumannomyces graminis	61.31	0.00e+00	823.00
IUUC-Gga-041021	Gallus gallus	39.96	5.00e-112	398.00
IUUC-Gac-042474	Gasterosteus aculeatus	41.25	1.00e-115	410.00
IUUC-Gma-043060	Glycine max	40.92	1.00e-109	390.00
IUUC-Ggo-044855	Gorilla gorilla	39.96	8.00e-112	397.00
IUUC-Hsa-046147	Homo sapiens	39.96	8.00e-112	397.00
IUUC-Hvu-047775	Hordeum vulgare	36.57	1.00e-107	383.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	39.78	4.00e-111	395.00
IUUC-Kpa-049098	Komagataella pastoris	42.26	2.00e-117	416.00
IUUC-Lch-049818	Latimeria chalumnae	39.08	2.00e-108	386.00
IUUC-Lpe-051017	Leersia perrieri	34.72	2.00e-103	369.00
IUUC-Loc-051777	Lepisosteus oculatus	41.44	5.00e-117	414.00
IUUC-Lma-052990	Leptosphaeria maculans	65.99	0.00e+00	886.00
IUUC-Laf-053727	Loxodonta africana	40.15	7.00e-112	397.00
IUUC-Mcc-055799	Macaca mulatta	39.96	8.00e-112	397.00
IUUC-Meu-056065	Macropus eugenii	36.61	7.00e-84	305.00
IUUC-Mor-057054	Magnaporthe oryzae	61.67	0.00e+00	831.00
IUUC-Mpo-057417	Magnaporthe poae	62.25	0.00e+00	850.00
IUUC-Mtr-057849	Medicago truncatula	41.48	2.00e-109	389.00
IUUC-Mla-058870	Melampsora laricipopulina	44.56	3.00e-142	498.00
IUUC-Mga-059580	Meleagris gallopavo	32.57	2.00e-60	226.00
IUUC-Mvi-060507	Microbotryum violaceum	47.68	1.00e-165	576.00
IUUC-Mmr-060816	Microcebus murinus	39.59	2.00e-110	393.00
IUUC-Mdo-062866	Monodelphis domestica	36.95	4.00e-85	309.00
IUUC-Mmu-063906	Mus musculus	39.78	3.00e-111	395.00
IUUC-Mac-064675	Musa acuminata	38.16	3.00e-108	384.00
IUUC-Mpu-066199	Mustela putorius furo	39.96	7.00e-112	397.00
IUUC-Mlu-067110	Myotis lucifugus	39.78	5.00e-110	391.00
IUUC-Nfi-068482	Neosartorya fischeri	77.89	0.00e+00	2401.00
IUUC-Ncr-068906	Neurospora crassa	62.53	0.00e+00	843.00
IUUC-Nle-069410	Nomascus leucogenys	39.96	7.00e-112	397.00
IUUC-Opr-070401	Ochotona princeps	41.03	4.00e-50	192.00
IUUC-Ont-072100	Oreochromis niloticus	41.07	2.00e-115	409.00
IUUC-Oan-073121	Ornithorhynchus anatinus	39.41	2.00e-109	390.00
IUUC-Ocu-074623	Oryctolagus cuniculus	39.78	4.00e-111	395.00
IUUC-Oba-075380	Oryza barthii	34.42	5.00e-93	334.00
IUUC-Obr-076915	Oryza brachyantha	35.17	3.00e-101	362.00
IUUC-Ogl-077055	Oryza glaberrima	35.31	5.00e-101	361.00
IUUC-Ogu-078892	Oryza glumaepatula	34.26	4.00e-93	335.00
IUUC-Oin-079256	Oryza indica	34.95	4.00e-100	358.00
IUUC-Olo-080343	Oryza longistaminata	34.95	2.00e-100	359.00
IUUC-Ome-081422	Oryza meridionalis	34.95	4.00e-100	358.00
IUUC-Oni-083047	Oryza nivara	34.42	2.00e-93	336.00
IUUC-Opu-083792	Oryza punctata	33.86	2.00e-92	333.00
IUUC-Oru-084439	Oryza rufipogon	34.26	7.00e-93	334.00
IUUC-Osa-085972	Oryza sativa	34.96	4.00e-100	357.00
IUUC-Ola-087173	Oryzias latipes	40.22	4.00e-113	402.00
IUUC-Olu-087871	Ostreococcus lucimarinus	38.07	5.00e-94	336.00
IUUC-Oga-087908	Otolemur garnettii	39.78	4.00e-111	395.00
IUUC-Oar-090277	Ovis aries	40.15	6.00e-112	397.00
IUUC-Ptr-091543	Pan troglodytes	39.96	8.00e-112	397.00
IUUC-Pan-092243	Papio anubis	39.96	8.00e-112	397.00
IUUC-Psi-093150	Pelodiscus sinensis	39.78	1.00e-111	397.00
IUUC-Pno-094891	Phaeosphaeria nodorum	65.48	0.00e+00	891.00
IUUC-Ppa-095181	Physcomitrella patens	42.94	1.00e-101	362.00
IUUC-Pfo-096267	Poecilia formosa	40.60	8.00e-114	404.00
IUUC-Pab-098072	Pongo abelii	39.96	8.00e-112	397.00
IUUC-Pop-099190	Populus trichocarpa	38.98	5.00e-108	384.00
IUUC-Pca-100311	Procavia capensis	40.15	5.00e-112	398.00
IUUC-Ppe-101284	Prunus persica	41.38	9.00e-113	400.00
IUUC-Pva-102215	Pteropus vampyrus	36.53	7.00e-95	341.00
IUUC-Pgr-103694	Puccinia graminis	46.29	4.00e-153	535.00
IUUC-Ptt-103916	Puccinia triticina	45.12	2.00e-144	506.00
IUUC-Pte-104346	Pyrenophora teres	60.21	0.00e+00	1125.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	59.22	0.00e+00	1118.00
IUUC-Rno-105315	Rattus norvegicus	39.78	3.00e-111	395.00
IUUC-Sce-106273	Saccharomyces cerevisiae	40.13	2.00e-107	382.00
IUUC-Sha-106835	Sarcophilus harrisii	39.78	5.00e-111	395.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	42.51	2.00e-134	472.00
IUUC-Spo-108081	Schizosaccharomyces pombe	41.92	2.00e-126	446.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	61.41	0.00e+00	1088.00
IUUC-Smo-109590	Selaginella moellendorffii	41.93	1.00e-101	363.00
IUUC-Sit-109757	Setaria italica	35.86	2.00e-107	383.00
IUUC-Sly-111557	Solanum lycopersicum	38.05	7.00e-115	407.00
IUUC-Stu-112896	Solanum tuberosum	37.61	8.00e-104	369.00
IUUC-Sar-113224	Sorex araneus	41.78	1.00e-78	287.00
IUUC-Sbi-114313	Sorghum bicolor	36.01	1.00e-110	393.00
IUUC-Sre-114993	Sporisorium reilianum	43.62	1.00e-152	533.00
IUUC-Ssc-115535	Sus scrofa	36.26	1.00e-92	333.00
IUUC-Tgu-117493	Taeniopygia guttata	32.57	2.00e-60	226.00
IUUC-Tru-118669	Takifugu rubripes	41.44	5.00e-116	411.00
IUUC-Tsy-119373	Tarsius syrichta	33.33	1.00e-68	254.00
IUUC-Tni-120049	Tetraodon nigroviridis	37.36	1.00e-89	322.00
IUUC-Tca-121779	Theobroma cacao	39.79	1.00e-107	384.00
IUUC-Tre-122195	Trichoderma reesei	54.10	0.00e+00	1012.00
IUUC-Tvi-122650	Trichoderma virens	54.22	0.00e+00	1030.00
IUUC-Tae-123099	Triticum aestivum	36.56	8.00e-108	384.00
IUUC-Tur-126295	Triticum urartu	37.01	3.00e-109	388.00
IUUC-Tme-126964	Tuber melanosporum	65.40	0.00e+00	837.00
IUUC-Tbe-128149	Tupaia belangeri	38.08	3.00e-61	229.00
IUUC-Ttr-128165	Tursiops truncatus	39.96	1.00e-111	397.00
IUUC-Uma-129365	Ustilago maydis	45.36	9.00e-140	490.00
IUUC-Vda-129725	Verticillium dahliae	65.22	0.00e+00	782.00
IUUC-Vpa-130678	Vicugna pacos	40.15	7.00e-112	397.00
IUUC-Vvi-131147	Vitis vinifera	39.35	2.00e-108	386.00
IUUC-Xtr-132636	Xenopus tropicalis	40.18	4.00e-110	392.00
IUUC-Xma-133458	Xiphophorus maculatus	40.33	1.00e-114	406.00
IUUC-Yli-134481	Yarrowia lipolytica	45.45	4.00e-147	514.00
IUUC-Zma-135657	Zea mays	36.76	4.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence