iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015536

Ensembl Protein ID

Bo5g108440.1

UniProt Accession

A0A0D3CHZ1; A0A0D3CHZ1_BRAOL

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo5g108440	Bo5g108440.1	Bo5g108440.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-53	182.3	310	796
UBD/Alpha-Helix/UBA	6.10e-16	59.5	615	655

Active Site

Position(s)	Description	Evidence
319	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
759	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklnee.npkepkgellkslqklfeel...............w.kskkkavsprellkalkke 80
           tGl NlgN+CY+ +++Q L++++++ + ++++++ kl+ e +p +p+ +l ++l+kl + l               + + +++ + pr++++++++ 
   Q: 310  TGLVNLGNSCYLAATMQILFSTHSFISRYFSHQSLKLAFEmAPADPTLDLNMQLTKLGHGLlsgkysipvtekdaaTaEARQEGIPPRMFKSVVAAG 406
           7*************************9999977777765515689999*************7888777777666552588888************** PP
   S: 81   aeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpv 176
           + efs+++qqDa +f+ +lld++e+                             +++ +   s+ F++ ++++i c + + ++ +r++  l+l++p+
   Q: 407  HGEFSSMRQQDALDFFLHLLDKVERGN---------------------------NTRPDLDPSRSFKFGVEEKILCSSGKVSYnKRDDCILSLNIPL 476
           ***********************9988...........................567888899*************776555544445555555555 PP
   S: 177  pgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqk 244
           ++ +  +k                               l+ cL+ f+++e++++   yy++  k+k++a k+++l+++P++L+lh+ +f +  +++
   Q: 477  QEAT--NKDeleafnnqtagkgleennmstdeivrprvPLEACLATFASPEQIHD---YYSTALKGKTTAIKTTGLTSFPDYLVLHMRKFVM-DAGW 567
           5555..444569*****************************************97...********************************65.567* PP
   S: 245  srekinkkvefpleLdlspfcts.......................................................................... 267
           +++k++ ++++p+ +d+s++ ++                                                                          
   Q: 568  VPKKLDVYIDVPDVIDISHMRSKglqpgeellpdgvpeevtetaqpvaneeivaqlvsmgfnqlhcqkaaintsnagveeatnwlfshmddpdidap 664
           ******************9999999999999999998888888888888888888888888777777777777766666666666666666666666 PP
   S: 268  .............peekqke...........................................................kkkYeLiavvvHsG.sls 291
                        +     +                                                             +Y+L+++v+H+G s++
   Q: 665  ishqasdvdqssvD-----TlisfgfaeevgrkalkasggdiekatdwifnnpnasvsdmdvsssssaqtpaqtglpdgGGRYKLFGIVSHMGtSTH 756
           66665555555550.....0555555555555555555566666666666666666666777777777788889999999***************** PP
   S: 292  sGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           +GHYva++ + +g+W+ f+DskV  +  ++  +   + +Y++f++r
   Q: 757  CGHYVAHILK-EGRWVIFNDSKVGIS--TDPPK---DMGYLYFFQR 796
           **********.9***********998..78888...999**99997 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++e++++qlv+MGF++ ++++a  ++ n  +e+A+++L+++
   Q: 615  ANEEIVAQLVSMGFNQLHCQKAAINTsNAGVEEATNWLFSH 655
           589************************************97 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MELLRSNLSR VQIPEPTHRI YKHECCLSFD TPRSEGGLFV DMNSFLAFGK DYVAWNHEKT 60
GNPVYLHIKE TPKSVPEDRP LKKPTLLAIG VDGGFDNSET EYEESYSIVI LPDFVSLPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTTC TCCGATCGAA CTTGTCTAGG GTTCAGATCC CAGAACCCAC CCACCGCATC 60
TACAAGCACG AGTGTTGCCT CTCCTTCGAT ACCCCGGTAA ACCCTCTCAC AGCTCGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	64.77	0.00e+00	996.00
IUUC-Aca-005368	Anolis carolinensis	48.68	0.00e+00	778.00
IUUC-Aly-005727	Arabidopsis lyrata	90.36	0.00e+00	1464.00
IUUC-Ath-006974	Arabidopsis thaliana	90.11	0.00e+00	1461.00
IUUC-Ago-007890	Ashbya gossypii	28.20	4.00e-70	259.00
IUUC-Acl-008057	Aspergillus clavatus	34.72	9.00e-119	421.00
IUUC-Afl-008547	Aspergillus flavus	37.54	2.00e-114	405.00
IUUC-Ang-009720	Aspergillus niger	35.21	7.00e-111	394.00
IUUC-Aor-010111	Aspergillus oryzae	35.35	5.00e-123	435.00
IUUC-Bra-017939	Brassica rapa	98.12	0.00e+00	1580.00
IUUC-Cel-018625	Caenorhabditis elegans	33.70	3.00e-117	416.00
IUUC-Csa-024177	Chlorocebus sabaeus	49.25	0.00e+00	676.00
IUUC-Ggr-040098	Gaeumannomyces graminis	35.45	5.00e-116	411.00
IUUC-Gma-043614	Glycine max	76.02	0.00e+00	1209.00
IUUC-Hvu-047563	Hordeum vulgare	68.70	0.00e+00	873.00
IUUC-Kpa-049156	Komagataella pastoris	32.13	2.00e-106	379.00
IUUC-Lch-049648	Latimeria chalumnae	48.50	0.00e+00	763.00
IUUC-Lpe-051523	Leersia perrieri	67.81	0.00e+00	1090.00
IUUC-Mor-057106	Magnaporthe oryzae	35.14	3.00e-119	422.00
IUUC-Mpo-057589	Magnaporthe poae	35.42	1.00e-115	410.00
IUUC-Mla-058903	Melampsora laricipopulina	35.35	5.00e-114	405.00
IUUC-Mvi-060476	Microbotryum violaceum	34.36	4.00e-105	375.00
IUUC-Ocu-074861	Oryctolagus cuniculus	49.10	0.00e+00	769.00
IUUC-Oba-075109	Oryza barthii	67.83	0.00e+00	1093.00
IUUC-Ogl-077065	Oryza glaberrima	69.44	0.00e+00	1138.00
IUUC-Ogu-078776	Oryza glumaepatula	67.70	0.00e+00	1110.00
IUUC-Oin-080048	Oryza indica	69.32	0.00e+00	1132.00
IUUC-Olo-080711	Oryza longistaminata	66.20	0.00e+00	1016.00
IUUC-Ome-081506	Oryza meridionalis	67.67	0.00e+00	1029.00
IUUC-Oni-082320	Oryza nivara	65.94	0.00e+00	1083.00
IUUC-Opu-083801	Oryza punctata	68.07	0.00e+00	1080.00
IUUC-Oru-085139	Oryza rufipogon	65.94	0.00e+00	1082.00
IUUC-Osa-085713	Oryza sativa	69.57	0.00e+00	1142.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.49	1.00e-104	374.00
IUUC-Ppa-095901	Physcomitrella patens	64.43	0.00e+00	1089.00
IUUC-Pab-098068	Pongo abelii	43.64	0.00e+00	632.00
IUUC-Pop-098943	Populus trichocarpa	77.18	0.00e+00	1236.00
IUUC-Pgr-103343	Puccinia graminis	33.82	2.00e-101	363.00
IUUC-Ptt-103928	Puccinia triticina	28.45	6.00e-90	325.00
IUUC-Spo-108144	Schizosaccharomyces pombe	34.68	6.00e-112	398.00
IUUC-Smo-108848	Selaginella moellendorffii	63.19	0.00e+00	981.00
IUUC-Sit-110728	Setaria italica	71.36	0.00e+00	1172.00
IUUC-Tni-120658	Tetraodon nigroviridis	44.51	0.00e+00	652.00
IUUC-Tre-122043	Trichoderma reesei	35.78	1.00e-114	407.00
IUUC-Tvi-122303	Trichoderma virens	35.90	1.00e-121	430.00
IUUC-Tae-123798	Triticum aestivum	69.15	0.00e+00	1122.00
IUUC-Tur-126732	Triticum urartu	64.43	0.00e+00	1036.00
IUUC-Tbe-127261	Tupaia belangeri	41.46	1.00e-122	433.00
IUUC-Vvi-131116	Vitis vinifera	76.64	0.00e+00	1222.00
IUUC-Yli-134510	Yarrowia lipolytica	34.78	5.00e-107	381.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence