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Tag Content
iUUCD ID IUUC-Smo-109325
Ensembl Protein ID EFJ28395
UniProt Accession D8RGP0; D8RGP0_SELML
Genbank Protein ID EFJ20409.1; EFJ28395.1
Protein Name Presenilin
Genbank Nucleotide ID GL377602; GL377579
Gene Name SELMODRAFT_55385; SELMODRAFT_65341
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SELMODRAFT_65341 EFJ28395 EFJ28395
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 36.00 5.00e-30 128.00 IUUC-Cel-018553
UBD/Alpha-Helix/CUE 35.85 3.00e-34 143.00 IUUC-Dre-028689
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Selaginella moellendorffii
Functional Description
(View)

Functional Description


     Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
 Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Protein Sequence
(Fasta)
SLLESLGAEL VSILAPVSAC MLFVVLLVRA LVVNSSQLQA PAIALVIYAE DPSDSTSEKL 60
GGALLNALVF VAFVTAATFL LVGLFYLRCT KCLRLYVSFS IFNVLVYLGA ALGVLFVQTY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Smo-109325|UBD,CUE|Selaginella moellendorffii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCCTGTTGG AGAGCCTTGG AGCGGAGCTG GTGTCCATCC TTGCTCCAGT CTCGGCGTGC 60
ATGCTCTTTG TCGTCCTTCT GGTAAGAGCC CTCGTCGTTA ACAGCAGCCA GCTCCAAGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Smo-109325|UBD,CUE|Selaginella moellendorffii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP
Pfam

PF01080--Presenilin
PRINTS

PR01072--PRESENILIN
SMART

SM00730--PSN
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing
KEGG smo:SELMODRAFT_55385; smo:SELMODRAFT_65341
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000686 Aegilops tauschii 40.69 7.00e-32 131.00
IUUC-Aml-001648 Ailuropoda melanoleuca 36.31 1.00e-34 139.00
IUUC-Atr-003039 Amborella trichopoda 43.83 7.00e-83 300.00
IUUC-Apl-003727 Anas platyrhynchos 36.59 2.00e-35 142.00
IUUC-Aca-004582 Anolis carolinensis 34.76 4.00e-34 138.00
IUUC-Aly-005455 Arabidopsis lyrata 52.44 2.00e-48 185.00
IUUC-Ath-006730 Arabidopsis thaliana 52.89 4.00e-50 191.00
IUUC-Ame-011500 Astyanax mexicanus 34.92 1.00e-33 136.00
IUUC-Bta-013026 Bos taurus 34.07 7.00e-35 140.00
IUUC-Bdi-014196 Brachypodium distachyon 41.87 3.00e-59 221.00
IUUC-Bol-015841 Brassica oleracea 46.50 5.00e-74 270.00
IUUC-Bra-017580 Brassica rapa 53.33 3.00e-35 141.00
IUUC-Cel-018553 Caenorhabditis elegans 36.73 2.00e-40 159.00
IUUC-Cja-019994 Callithrix jacchus 36.65 4.00e-35 141.00
IUUC-Cfa-020074 Canis familiaris 36.89 3.00e-35 142.00
IUUC-Cpo-022237 Cavia porcellus 37.71 6.00e-35 140.00
IUUC-Cre-022747 Chlamydomonas reinhardtii 46.78 6.00e-49 187.00
IUUC-Csa-023537 Chlorocebus sabaeus 37.71 2.00e-34 139.00
IUUC-Cho-024735 Choloepus hoffmanni 38.97 2.00e-33 135.00
IUUC-Cin-025780 Ciona intestinalis 33.75 1.00e-44 172.00
IUUC-Csv-025967 Ciona savignyi 32.75 3.00e-43 168.00
IUUC-Dre-028689 Danio rerio 34.58 2.00e-34 139.00
IUUC-Dno-029758 Dasypus novemcinctus 36.84 5.00e-34 138.00
IUUC-Dor-031127 Dipodomys ordii 32.44 2.00e-20 92.80
IUUC-Dme-031929 Drosophila melanogaster 33.01 3.00e-42 165.00
IUUC-Ete-032487 Echinops telfairi 38.01 6.00e-17 81.30
IUUC-Eca-034387 Equus caballus 35.40 2.00e-25 109.00
IUUC-Eeu-035134 Erinaceus europaeus 38.62 2.00e-33 135.00
IUUC-Fca-036243 Felis catus 36.60 4.00e-35 141.00
IUUC-Fal-036600 Ficedula albicollis 35.08 8.00e-34 137.00
IUUC-Gmo-039665 Gadus morhua 34.44 1.00e-29 123.00
IUUC-Gga-040993 Gallus gallus 35.91 3.00e-35 142.00
IUUC-Gac-042511 Gasterosteus aculeatus 35.73 1.00e-33 137.00
IUUC-Gma-043822 Glycine max 47.31 2.00e-61 229.00
IUUC-Ggo-045338 Gorilla gorilla 34.25 6.00e-23 101.00
IUUC-Hsa-046822 Homo sapiens 37.71 2.00e-34 139.00
IUUC-Hvu-047141 Hordeum vulgare 42.28 5.00e-65 240.00
IUUC-Itr-048420 Ictidomys tridecemlineatus 39.38 4.00e-36 144.00
IUUC-Lch-049638 Latimeria chalumnae 31.19 1.00e-28 119.00
IUUC-Lpe-051132 Leersia perrieri 54.41 4.00e-34 138.00
IUUC-Loc-052427 Lepisosteus oculatus 35.73 9.00e-36 143.00
IUUC-Laf-053758 Loxodonta africana 34.90 5.00e-36 144.00
IUUC-Mcc-055682 Macaca mulatta 37.71 2.00e-34 139.00
IUUC-Meu-056004 Macropus eugenii 46.23 9.00e-21 94.00
IUUC-Mtr-058392 Medicago truncatula 46.68 2.00e-76 278.00
IUUC-Mga-059466 Meleagris gallopavo 35.91 5.00e-35 141.00
IUUC-Mmr-060890 Microcebus murinus 35.13 1.00e-26 113.00
IUUC-Mdo-062122 Monodelphis domestica 36.54 2.00e-35 142.00
IUUC-Mmu-063176 Mus musculus 36.49 5.00e-34 137.00
IUUC-Mac-064858 Musa acuminata 52.97 1.00e-38 152.00
IUUC-Mpu-065927 Mustela putorius furo 36.31 1.00e-34 139.00
IUUC-Mlu-067079 Myotis lucifugus 36.60 2.00e-39 155.00
IUUC-Nle-070180 Nomascus leucogenys 37.71 2.00e-34 139.00
IUUC-Opr-070847 Ochotona princeps 35.23 6.00e-32 130.00
IUUC-Ont-071846 Oreochromis niloticus 33.67 1.00e-32 133.00
IUUC-Oan-072783 Ornithorhynchus anatinus 39.57 1.00e-34 139.00
IUUC-Ocu-074527 Oryctolagus cuniculus 36.99 3.00e-35 142.00
IUUC-Oba-075256 Oryza barthii 43.26 2.00e-57 215.00
IUUC-Obr-076302 Oryza brachyantha 54.48 8.00e-34 137.00
IUUC-Ogl-077097 Oryza glaberrima 43.36 7.00e-64 237.00
IUUC-Ogu-078570 Oryza glumaepatula 44.55 4.00e-62 231.00
IUUC-Oin-079244 Oryza indica 42.48 8.00e-64 236.00
IUUC-Olo-080484 Oryza longistaminata 64.60 2.00e-33 135.00
IUUC-Ome-081814 Oryza meridionalis 48.48 5.00e-34 137.00
IUUC-Oni-082057 Oryza nivara 43.56 4.00e-62 231.00
IUUC-Opu-084176 Oryza punctata 65.49 2.00e-34 139.00
IUUC-Oru-084618 Oryza rufipogon 44.55 6.00e-62 230.00
IUUC-Osa-085602 Oryza sativa 44.33 8.00e-63 233.00
IUUC-Ola-086707 Oryzias latipes 33.33 3.00e-23 101.00
IUUC-Olu-087811 Ostreococcus lucimarinus 37.82 2.00e-56 211.00
IUUC-Oga-088560 Otolemur garnettii 30.58 9.00e-23 100.00
IUUC-Oar-090348 Ovis aries 36.96 9.00e-36 144.00
IUUC-Ptr-091060 Pan troglodytes 37.71 2.00e-34 139.00
IUUC-Pan-091855 Papio anubis 37.96 2.00e-34 139.00
IUUC-Psi-093505 Pelodiscus sinensis 34.52 5.00e-34 137.00
IUUC-Pma-094612 Petromyzon marinus 36.40 1.00e-29 123.00
IUUC-Ppa-095431 Physcomitrella patens 45.78 2.00e-95 342.00
IUUC-Pfo-097396 Poecilia formosa 34.17 4.00e-38 151.00
IUUC-Pab-098591 Pongo abelii 37.71 2.00e-34 139.00
IUUC-Pop-099661 Populus trichocarpa 49.63 2.00e-83 302.00
IUUC-Pca-101029 Procavia capensis 40.41 3.00e-34 138.00
IUUC-Ppe-101495 Prunus persica 45.63 1.00e-81 295.00
IUUC-Pva-102244 Pteropus vampyrus 33.99 5.00e-32 131.00
IUUC-Rno-105861 Rattus norvegicus 35.16 1.00e-33 136.00
IUUC-Sha-107045 Sarcophilus harrisii 36.16 1.00e-35 143.00
IUUC-Sit-110624 Setaria italica 75.86 2.00e-33 135.00
IUUC-Sly-110865 Solanum lycopersicum 69.01 6.00e-25 104.00
IUUC-Stu-112433 Solanum tuberosum 47.52 6.00e-75 273.00
IUUC-Sar-113169 Sorex araneus 39.66 3.00e-33 135.00
IUUC-Sbi-114305 Sorghum bicolor 62.61 2.00e-33 135.00
IUUC-Ssc-115766 Sus scrofa 37.25 1.00e-35 143.00
IUUC-Tgu-116469 Taeniopygia guttata 38.33 2.00e-34 138.00
IUUC-Tru-117732 Takifugu rubripes 33.75 3.00e-33 135.00
IUUC-Tsy-119624 Tarsius syrichta 35.14 7.00e-33 134.00
IUUC-Tni-119852 Tetraodon nigroviridis 35.16 2.00e-32 132.00
IUUC-Tca-121865 Theobroma cacao 46.15 1.00e-78 286.00
IUUC-Tae-123984 Triticum aestivum 42.38 3.00e-63 234.00
IUUC-Tur-126237 Triticum urartu 77.01 6.00e-34 137.00
IUUC-Tbe-128148 Tupaia belangeri 34.66 4.00e-21 94.70
IUUC-Ttr-128793 Tursiops truncatus 37.54 2.00e-33 135.00
IUUC-Vpa-130625 Vicugna pacos 36.75 3.00e-29 122.00
IUUC-Vvi-131312 Vitis vinifera 45.73 1.00e-76 279.00
IUUC-Xtr-131790 Xenopus tropicalis 35.25 3.00e-35 142.00
IUUC-Xma-133377 Xiphophorus maculatus 35.47 5.00e-36 144.00
Created Date 25-Jun-2017

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