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Tag Content
UUCD2 ID IUUC-Tni-120142
UUCD1 version UUC-TeN-00480
Ensembl Protein ID ENSTNIP00000014022.1
UniProt Accession H3D0I6; H3D0I6_TETNG
Protein Name Coatomer subunit beta'
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTNIG00000011087.1 ENSTNIT00000014218.1 ENSTNIP00000014022.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-34 116.1 182 223
UBD/Beta-Prp 1.10e-71 241.6 13 289
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 182  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 223
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +   +gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCS-QVEGHTHYVMQIVMNPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 188
           *******************************999.99********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 189  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 277
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 278  GLRGSNNVALGY 289
           *99999987544 PP
   
Organism Tetraodon nigroviridis
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
QPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tni-120142|E3,WD_repeat;UBD,Beta-Prp|Tetraodon nigroviridis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGCCTCTGA GGCTGGACAT CAAGCGGAGG CTGACAGCCA GATCTGACCG AGTGAAGAGT 60
GTGGATCTTC ACCCAACAGA ACCATGGATG TTGGCTAGCC TGTACAACGG CAGCGTCTGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tni-120142|E3,WD_repeat;UBD,Beta-Prp|Tetraodon nigroviridis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 52.69 0.00e+00 921.00
IUUC-Aml-002154 Ailuropoda melanoleuca 89.51 0.00e+00 1674.00
IUUC-Atr-003090 Amborella trichopoda 59.59 0.00e+00 1059.00
IUUC-Apl-003976 Anas platyrhynchos 92.33 0.00e+00 1679.00
IUUC-Aca-004301 Anolis carolinensis 93.37 0.00e+00 1668.00
IUUC-Aly-006508 Arabidopsis lyrata 60.70 0.00e+00 1080.00
IUUC-Ath-007630 Arabidopsis thaliana 61.09 0.00e+00 1095.00
IUUC-Ago-007914 Ashbya gossypii 46.24 0.00e+00 747.00
IUUC-Acl-008237 Aspergillus clavatus 56.25 0.00e+00 955.00
IUUC-Afl-008535 Aspergillus flavus 53.11 0.00e+00 904.00
IUUC-Afu-008845 Aspergillus fumigatus 53.61 0.00e+00 930.00
IUUC-Ani-009135 Aspergillus nidulans 55.97 0.00e+00 905.00
IUUC-Ang-009654 Aspergillus niger 55.75 0.00e+00 849.00
IUUC-Aor-009939 Aspergillus oryzae 53.58 0.00e+00 963.00
IUUC-Ate-010355 Aspergillus terreus 54.03 0.00e+00 906.00
IUUC-Ame-010922 Astyanax mexicanus 86.49 0.00e+00 1533.00
IUUC-Bgr-012249 Blumeria graminis 53.64 0.00e+00 910.00
IUUC-Bta-013579 Bos taurus 94.95 0.00e+00 1435.00
IUUC-Bci-013866 Botrytis cinerea 55.21 0.00e+00 911.00
IUUC-Bdi-015046 Brachypodium distachyon 60.60 0.00e+00 1096.00
IUUC-Bol-015731 Brassica oleracea 59.60 0.00e+00 1101.00
IUUC-Bra-017758 Brassica rapa 59.91 0.00e+00 1099.00
IUUC-Cel-018387 Caenorhabditis elegans 62.73 0.00e+00 1164.00
IUUC-Cja-019145 Callithrix jacchus 89.74 0.00e+00 1679.00
IUUC-Cfa-020564 Canis familiaris 89.74 0.00e+00 1673.00
IUUC-Cpo-022201 Cavia porcellus 90.07 0.00e+00 1662.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 59.27 0.00e+00 983.00
IUUC-Csa-023383 Chlorocebus sabaeus 93.99 0.00e+00 1136.00
IUUC-Cho-024454 Choloepus hoffmanni 88.30 0.00e+00 1357.00
IUUC-Cin-025681 Ciona intestinalis 77.75 0.00e+00 1357.00
IUUC-Csv-026012 Ciona savignyi 77.19 0.00e+00 1338.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 52.43 0.00e+00 838.00
IUUC-Cne-026986 Cryptococcus neoformans 50.67 0.00e+00 897.00
IUUC-Cme-027219 Cyanidioschyzon merolae 47.80 0.00e+00 840.00
IUUC-Dre-027846 Danio rerio 94.84 0.00e+00 1707.00
IUUC-Dor-030462 Dipodomys ordii 89.01 0.00e+00 1229.00
IUUC-Dse-031268 Dothistroma septosporum 54.66 0.00e+00 939.00
IUUC-Dme-031791 Drosophila melanogaster 72.24 0.00e+00 1260.00
IUUC-Ete-033166 Echinops telfairi 85.10 0.00e+00 980.00
IUUC-Eca-034180 Equus caballus 88.03 0.00e+00 1612.00
IUUC-Eeu-035086 Erinaceus europaeus 76.94 0.00e+00 793.00
IUUC-Fca-036265 Felis catus 88.74 0.00e+00 1668.00
IUUC-Fal-037202 Ficedula albicollis 91.13 0.00e+00 1627.00
IUUC-Fox-037711 Fusarium oxysporum 55.27 0.00e+00 873.00
IUUC-Fso-038268 Fusarium solani 55.51 0.00e+00 872.00
IUUC-Gmo-039046 Gadus morhua 95.73 0.00e+00 1702.00
IUUC-Ggr-039863 Gaeumannomyces graminis 54.56 0.00e+00 888.00
IUUC-Gga-041112 Gallus gallus 90.67 0.00e+00 1680.00
IUUC-Gac-041733 Gasterosteus aculeatus 97.52 0.00e+00 1697.00
IUUC-Gma-044333 Glycine max 62.23 0.00e+00 1106.00
IUUC-Ggo-044984 Gorilla gorilla 89.40 0.00e+00 1673.00
IUUC-Hsa-046698 Homo sapiens 89.51 0.00e+00 1674.00
IUUC-Hvu-047669 Hordeum vulgare 70.14 2.00e-166 577.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 89.42 0.00e+00 1659.00
IUUC-Kpa-049265 Komagataella pastoris 49.07 0.00e+00 858.00
IUUC-Lch-050473 Latimeria chalumnae 89.14 0.00e+00 1692.00
IUUC-Lpe-051579 Leersia perrieri 61.29 0.00e+00 1082.00
IUUC-Loc-052675 Lepisosteus oculatus 94.12 0.00e+00 1700.00
IUUC-Lma-053218 Leptosphaeria maculans 54.34 0.00e+00 912.00
IUUC-Laf-053757 Loxodonta africana 89.43 0.00e+00 1668.00
IUUC-Mcc-054859 Macaca mulatta 89.74 0.00e+00 1679.00
IUUC-Meu-056174 Macropus eugenii 88.48 0.00e+00 702.00
IUUC-Mor-057264 Magnaporthe oryzae 55.04 0.00e+00 875.00
IUUC-Mpo-057538 Magnaporthe poae 54.80 0.00e+00 902.00
IUUC-Mtr-058310 Medicago truncatula 61.99 0.00e+00 1115.00
IUUC-Mla-058937 Melampsora laricipopulina 53.08 0.00e+00 894.00
IUUC-Mga-059875 Meleagris gallopavo 91.77 0.00e+00 1670.00
IUUC-Mvi-060240 Microbotryum violaceum 50.81 0.00e+00 901.00
IUUC-Mmr-061261 Microcebus murinus 89.74 0.00e+00 1679.00
IUUC-Mdo-062076 Monodelphis domestica 90.05 0.00e+00 1673.00
IUUC-Mmu-063324 Mus musculus 89.85 0.00e+00 1677.00
IUUC-Mac-064636 Musa acuminata 60.72 0.00e+00 1077.00
IUUC-Mpu-065961 Mustela putorius furo 89.62 0.00e+00 1673.00
IUUC-Mlu-067059 Myotis lucifugus 91.63 0.00e+00 1603.00
IUUC-Nfi-068277 Neosartorya fischeri 52.61 0.00e+00 919.00
IUUC-Ncr-068659 Neurospora crassa 52.87 0.00e+00 902.00
IUUC-Nle-069034 Nomascus leucogenys 89.85 0.00e+00 1678.00
IUUC-Opr-070334 Ochotona princeps 94.29 0.00e+00 1469.00
IUUC-Ont-071563 Oreochromis niloticus 93.08 0.00e+00 1750.00
IUUC-Oan-073416 Ornithorhynchus anatinus 92.67 0.00e+00 1586.00
IUUC-Ocu-074522 Oryctolagus cuniculus 89.51 0.00e+00 1673.00
IUUC-Oba-075760 Oryza barthii 60.44 0.00e+00 1061.00
IUUC-Obr-076163 Oryza brachyantha 62.22 0.00e+00 1085.00
IUUC-Ogl-077450 Oryza glaberrima 61.68 0.00e+00 1090.00
IUUC-Ogu-078994 Oryza glumaepatula 60.44 0.00e+00 1060.00
IUUC-Oin-079856 Oryza indica 60.32 0.00e+00 1063.00
IUUC-Olo-080731 Oryza longistaminata 59.23 0.00e+00 1046.00
IUUC-Ome-081762 Oryza meridionalis 56.08 0.00e+00 983.00
IUUC-Oni-082324 Oryza nivara 60.44 0.00e+00 1060.00
IUUC-Opu-083400 Oryza punctata 58.59 0.00e+00 1053.00
IUUC-Oru-084829 Oryza rufipogon 60.44 0.00e+00 1061.00
IUUC-Osa-086026 Oryza sativa 61.68 0.00e+00 1092.00
IUUC-Ola-087245 Oryzias latipes 92.03 0.00e+00 1750.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.55 0.00e+00 1041.00
IUUC-Oga-088163 Otolemur garnettii 86.67 0.00e+00 1607.00
IUUC-Oar-089842 Ovis aries 90.18 0.00e+00 1666.00
IUUC-Ptr-090501 Pan troglodytes 89.74 0.00e+00 1676.00
IUUC-Pan-092011 Papio anubis 89.74 0.00e+00 1679.00
IUUC-Psi-093308 Pelodiscus sinensis 93.62 0.00e+00 1674.00
IUUC-Pma-094695 Petromyzon marinus 75.43 0.00e+00 1429.00
IUUC-Pno-094785 Phaeosphaeria nodorum 61.03 2.00e-110 393.00
IUUC-Ppa-095911 Physcomitrella patens 60.85 0.00e+00 1110.00
IUUC-Pfo-096587 Poecilia formosa 90.86 0.00e+00 1749.00
IUUC-Pab-097926 Pongo abelii 87.49 0.00e+00 1582.00
IUUC-Pop-099634 Populus trichocarpa 61.38 0.00e+00 1098.00
IUUC-Pca-100965 Procavia capensis 88.41 0.00e+00 1627.00
IUUC-Ppe-101470 Prunus persica 61.62 0.00e+00 1103.00
IUUC-Pva-102451 Pteropus vampyrus 88.40 0.00e+00 1226.00
IUUC-Pgr-103453 Puccinia graminis 52.83 0.00e+00 908.00
IUUC-Ptt-103868 Puccinia triticina 53.18 0.00e+00 906.00
IUUC-Pte-104274 Pyrenophora teres 55.39 0.00e+00 945.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.72 0.00e+00 893.00
IUUC-Rno-105979 Rattus norvegicus 81.28 0.00e+00 1226.00
IUUC-Sce-106269 Saccharomyces cerevisiae 46.92 0.00e+00 775.00
IUUC-Sha-106905 Sarcophilus harrisii 91.33 0.00e+00 1667.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.09 0.00e+00 820.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.02 0.00e+00 812.00
IUUC-Smo-108695 Selaginella moellendorffii 61.90 0.00e+00 1072.00
IUUC-Sit-110692 Setaria italica 62.23 0.00e+00 1088.00
IUUC-Sly-111525 Solanum lycopersicum 61.86 0.00e+00 1106.00
IUUC-Stu-112906 Solanum tuberosum 60.59 0.00e+00 984.00
IUUC-Sar-113472 Sorex araneus 87.38 0.00e+00 1120.00
IUUC-Sbi-114052 Sorghum bicolor 62.89 0.00e+00 1110.00
IUUC-Sre-115040 Sporisorium reilianum 52.07 0.00e+00 903.00
IUUC-Ssc-115593 Sus scrofa 89.51 0.00e+00 1673.00
IUUC-Tgu-117239 Taeniopygia guttata 91.31 0.00e+00 1684.00
IUUC-Tru-118025 Takifugu rubripes 98.47 0.00e+00 1748.00
IUUC-Tsy-118824 Tarsius syrichta 86.60 0.00e+00 1124.00
IUUC-Tca-121613 Theobroma cacao 61.38 0.00e+00 1098.00
IUUC-Tre-122072 Trichoderma reesei 54.68 0.00e+00 918.00
IUUC-Tvi-122546 Trichoderma virens 54.06 0.00e+00 902.00
IUUC-Tae-125385 Triticum aestivum 59.88 0.00e+00 1077.00
IUUC-Tur-126283 Triticum urartu 53.55 0.00e+00 920.00
IUUC-Tme-127041 Tuber melanosporum 56.54 0.00e+00 969.00
IUUC-Tbe-127770 Tupaia belangeri 88.70 0.00e+00 1231.00
IUUC-Ttr-129294 Tursiops truncatus 89.85 0.00e+00 1679.00
IUUC-Uma-129351 Ustilago maydis 50.73 0.00e+00 892.00
IUUC-Vda-129716 Verticillium dahliae 54.37 0.00e+00 938.00
IUUC-Vpa-130037 Vicugna pacos 79.08 0.00e+00 834.00
IUUC-Vvi-131689 Vitis vinifera 61.86 0.00e+00 1098.00
IUUC-Xtr-132633 Xenopus tropicalis 88.19 0.00e+00 1647.00
IUUC-Xma-133347 Xiphophorus maculatus 92.35 0.00e+00 1757.00
IUUC-Yli-134455 Yarrowia lipolytica 50.64 0.00e+00 835.00
IUUC-Zma-135706 Zea mays 61.09 0.00e+00 1102.00
Created Date 25-Jun-2017

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