iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013217

Ensembl Protein ID

ENSBTAP00000018087.5

UniProt Accession

F1MTQ0; F1MTQ0_BOVIN

Genbank Protein ID

ENSBTAP00000018087

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02003179

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000013602.5	ENSBTAT00000018087.5	ENSBTAP00000018087.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-35	118.4	184	221
UBD/Beta-Prp	4.50e-55	187.1	286	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 286  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 374
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 375  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 463
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 464  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 543
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAEPSPARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKDCRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGC GCCTGAGGTA GAGGGACGCC GGCCCGGTCA GGCCTCGGCG CGGCCTACAC 60
GCTTTGCTCG CCCGCTCCCG CCCCGGCCCC CGCCCGGCCA TGGCGGAGCC CTCGCCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.48	1.00e-62	236.00
IUUC-Aml-002332	Ailuropoda melanoleuca	86.29	0.00e+00	3345.00
IUUC-Atr-002600	Amborella trichopoda	29.60	2.00e-67	252.00
IUUC-Apl-004083	Anas platyrhynchos	57.89	0.00e+00	2142.00
IUUC-Aly-006517	Arabidopsis lyrata	30.28	1.00e-72	269.00
IUUC-Ath-006577	Arabidopsis thaliana	30.13	1.00e-71	265.00
IUUC-Ame-010718	Astyanax mexicanus	70.74	0.00e+00	1178.00
IUUC-Bdi-014797	Brachypodium distachyon	29.91	3.00e-60	227.00
IUUC-Bol-015737	Brassica oleracea	29.47	3.00e-73	271.00
IUUC-Bra-017961	Brassica rapa	29.84	2.00e-72	268.00
IUUC-Cja-019966	Callithrix jacchus	87.24	0.00e+00	3598.00
IUUC-Cfa-021037	Canis familiaris	89.20	0.00e+00	3704.00
IUUC-Cpo-021934	Cavia porcellus	91.61	0.00e+00	2734.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.15	1.00e-34	142.00
IUUC-Csa-023352	Chlorocebus sabaeus	87.09	0.00e+00	3435.00
IUUC-Cho-024690	Choloepus hoffmanni	78.67	0.00e+00	1367.00
IUUC-Csv-025813	Ciona savignyi	42.25	2.00e-178	619.00
IUUC-Dre-028205	Danio rerio	69.01	0.00e+00	1154.00
IUUC-Dno-028938	Dasypus novemcinctus	84.38	0.00e+00	3554.00
IUUC-Dme-031752	Drosophila melanogaster	49.68	0.00e+00	671.00
IUUC-Ete-032717	Echinops telfairi	80.08	0.00e+00	810.00
IUUC-Eca-034349	Equus caballus	90.11	0.00e+00	3597.00
IUUC-Fca-035485	Felis catus	89.19	0.00e+00	3109.00
IUUC-Gma-043340	Glycine max	30.22	3.00e-70	261.00
IUUC-Ggo-045500	Gorilla gorilla	87.61	0.00e+00	3665.00
IUUC-Hsa-046350	Homo sapiens	88.07	0.00e+00	3705.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.25	0.00e+00	1125.00
IUUC-Lch-049662	Latimeria chalumnae	57.38	0.00e+00	2108.00
IUUC-Lpe-051619	Leersia perrieri	30.92	8.00e-70	259.00
IUUC-Laf-053848	Loxodonta africana	86.85	0.00e+00	3560.00
IUUC-Mcc-054638	Macaca mulatta	88.15	0.00e+00	3685.00
IUUC-Meu-056739	Macropus eugenii	79.77	0.00e+00	1113.00
IUUC-Mtr-058094	Medicago truncatula	30.70	7.00e-72	266.00
IUUC-Mga-060165	Meleagris gallopavo	77.91	0.00e+00	2278.00
IUUC-Mmr-061227	Microcebus murinus	88.58	0.00e+00	3677.00
IUUC-Mdo-062074	Monodelphis domestica	70.94	0.00e+00	2816.00
IUUC-Mmu-064075	Mus musculus	81.80	0.00e+00	2949.00
IUUC-Mac-065343	Musa acuminata	30.56	9.00e-76	279.00
IUUC-Mpu-066643	Mustela putorius furo	92.03	0.00e+00	3025.00
IUUC-Mlu-067735	Myotis lucifugus	87.46	0.00e+00	3552.00
IUUC-Nle-069402	Nomascus leucogenys	91.24	0.00e+00	2964.00
IUUC-Oan-072954	Ornithorhynchus anatinus	71.34	0.00e+00	2872.00
IUUC-Ocu-074456	Oryctolagus cuniculus	85.95	0.00e+00	3565.00
IUUC-Oba-075709	Oryza barthii	29.91	3.00e-60	227.00
IUUC-Obr-076619	Oryza brachyantha	30.90	3.00e-70	260.00
IUUC-Ogl-077493	Oryza glaberrima	27.29	2.00e-29	125.00
IUUC-Opu-083233	Oryza punctata	30.20	1.00e-64	242.00
IUUC-Oru-085195	Oryza rufipogon	29.91	4.00e-60	227.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.06	4.00e-55	210.00
IUUC-Oga-087938	Otolemur garnettii	80.95	0.00e+00	3151.00
IUUC-Oar-090214	Ovis aries	98.03	0.00e+00	3972.00
IUUC-Ptr-091213	Pan troglodytes	88.45	0.00e+00	3657.00
IUUC-Pan-092444	Papio anubis	87.30	0.00e+00	3667.00
IUUC-Pma-094427	Petromyzon marinus	66.67	5.00e-132	463.00
IUUC-Ppa-095793	Physcomitrella patens	30.10	3.00e-74	274.00
IUUC-Pab-097573	Pongo abelii	86.73	0.00e+00	3549.00
IUUC-Pop-099672	Populus trichocarpa	30.89	4.00e-72	267.00
IUUC-Pca-100759	Procavia capensis	70.83	0.00e+00	1160.00
IUUC-Ppe-101849	Prunus persica	29.90	2.00e-75	278.00
IUUC-Pva-102782	Pteropus vampyrus	88.49	0.00e+00	3628.00
IUUC-Rno-105687	Rattus norvegicus	77.84	0.00e+00	3242.00
IUUC-Sly-111348	Solanum lycopersicum	30.41	2.00e-75	278.00
IUUC-Sar-113519	Sorex araneus	82.00	0.00e+00	1789.00
IUUC-Sbi-114195	Sorghum bicolor	29.09	6.00e-58	218.00
IUUC-Tsy-118921	Tarsius syrichta	89.12	0.00e+00	1976.00
IUUC-Tca-121098	Theobroma cacao	31.11	2.00e-79	291.00
IUUC-Tae-125478	Triticum aestivum	30.26	4.00e-72	267.00
IUUC-Tur-126809	Triticum urartu	30.22	2.00e-69	258.00
IUUC-Tbe-127663	Tupaia belangeri	77.36	0.00e+00	1321.00
IUUC-Ttr-128561	Tursiops truncatus	89.42	0.00e+00	3610.00
IUUC-Vpa-130444	Vicugna pacos	87.92	0.00e+00	3452.00
IUUC-Vvi-131362	Vitis vinifera	30.88	1.00e-73	272.00
IUUC-Xma-133633	Xiphophorus maculatus	70.80	0.00e+00	1128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence