iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098402

Ensembl Protein ID

ENSPPYP00000018794.1

UniProt Accession

H2PJM7; H2PJM7_PONAB

Genbank Protein ID

ENSPPYP00000018794

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01362220

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000016790.1	ENSPPYT00000019536.1	ENSPPYP00000018794.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-34	117.1	181	218
UBD/Beta-Prp	3.50e-52	177.5	280	541

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 218
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl.....lrsl.sgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l      +++ +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 280  SGSKRYLSSTGADGTICFWLWDAGTLkinprPAKFtERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 368
           67899***********999999999988988555547777888765522777888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs +++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 369  DSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSIlldmatrpagqnlqgiEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQ 457
           ********************************99***************888899999******************************* PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 458  LIHVLMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 541
           ******9.*********999999..89******************999998875544445566667777999999999999988887 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSCERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVLIREVA EKELLPRRTD WTGKEHPRTY 60
QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCKHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGTG AGAGGAAAGG CCTCTCGGAG CTGCGATCGG GTAAGTCGGG GGGCTGCCGG 60
GGCCGCTGGC ACCGGGCGAT TCCGCCCGCG GTCCCCCGCC CCCCGCCGCC CGACCGCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0022604--P:regulation of cell morphogenesis

KEGG

pon:100435026

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.54	5.00e-63	237.00
IUUC-Aml-002299	Ailuropoda melanoleuca	96.41	0.00e+00	3206.00
IUUC-Atr-002600	Amborella trichopoda	31.69	3.00e-71	264.00
IUUC-Apl-003700	Anas platyrhynchos	86.77	0.00e+00	2873.00
IUUC-Aca-004474	Anolis carolinensis	82.75	0.00e+00	2838.00
IUUC-Aly-006406	Arabidopsis lyrata	31.33	5.00e-68	253.00
IUUC-Ath-006801	Arabidopsis thaliana	31.03	1.00e-68	256.00
IUUC-Bta-013125	Bos taurus	95.68	0.00e+00	3110.00
IUUC-Bol-015737	Brassica oleracea	31.66	9.00e-72	266.00
IUUC-Bra-017961	Brassica rapa	32.11	4.00e-71	264.00
IUUC-Cja-018868	Callithrix jacchus	96.27	0.00e+00	3375.00
IUUC-Cfa-021179	Canis familiaris	95.72	0.00e+00	3176.00
IUUC-Cpo-022077	Cavia porcellus	91.50	0.00e+00	3080.00
IUUC-Csa-023618	Chlorocebus sabaeus	98.90	0.00e+00	3420.00
IUUC-Cho-024794	Choloepus hoffmanni	90.75	0.00e+00	875.00
IUUC-Csv-025813	Ciona savignyi	43.52	0.00e+00	632.00
IUUC-Dre-028029	Danio rerio	80.25	0.00e+00	1353.00
IUUC-Dno-030048	Dasypus novemcinctus	95.57	0.00e+00	3222.00
IUUC-Dor-030195	Dipodomys ordii	85.00	0.00e+00	1466.00
IUUC-Dme-031752	Drosophila melanogaster	51.28	0.00e+00	663.00
IUUC-Ete-032748	Echinops telfairi	83.58	0.00e+00	1158.00
IUUC-Eca-034274	Equus caballus	97.21	0.00e+00	3174.00
IUUC-Eeu-034688	Erinaceus europaeus	84.99	0.00e+00	1414.00
IUUC-Fca-035451	Felis catus	95.86	0.00e+00	3056.00
IUUC-Fal-037465	Ficedula albicollis	85.73	0.00e+00	2892.00
IUUC-Gmo-039451	Gadus morhua	68.58	0.00e+00	722.00
IUUC-Gga-040798	Gallus gallus	86.66	0.00e+00	2978.00
IUUC-Ggo-045347	Gorilla gorilla	96.64	0.00e+00	1668.00
IUUC-Hsa-046757	Homo sapiens	99.67	0.00e+00	3405.00
IUUC-Hvu-047706	Hordeum vulgare	31.84	1.00e-37	149.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	94.03	0.00e+00	1186.00
IUUC-Lch-050646	Latimeria chalumnae	78.40	0.00e+00	2758.00
IUUC-Lpe-051619	Leersia perrieri	31.56	1.00e-69	259.00
IUUC-Laf-054140	Loxodonta africana	96.02	0.00e+00	3207.00
IUUC-Mcc-055061	Macaca mulatta	98.68	0.00e+00	3408.00
IUUC-Mtr-058094	Medicago truncatula	32.66	8.00e-73	269.00
IUUC-Mmr-060837	Microcebus murinus	97.80	0.00e+00	1670.00
IUUC-Mdo-061903	Monodelphis domestica	95.60	0.00e+00	1728.00
IUUC-Mmu-063772	Mus musculus	94.89	0.00e+00	3274.00
IUUC-Mac-065343	Musa acuminata	30.68	1.00e-75	278.00
IUUC-Mpu-066359	Mustela putorius furo	96.42	0.00e+00	2952.00
IUUC-Mlu-067928	Myotis lucifugus	94.90	0.00e+00	3219.00
IUUC-Nle-070094	Nomascus leucogenys	98.68	0.00e+00	3357.00
IUUC-Opr-070971	Ochotona princeps	74.69	0.00e+00	956.00
IUUC-Ont-072221	Oreochromis niloticus	76.17	0.00e+00	1329.00
IUUC-Oan-073185	Ornithorhynchus anatinus	87.52	0.00e+00	2893.00
IUUC-Ocu-074033	Oryctolagus cuniculus	95.19	0.00e+00	2874.00
IUUC-Obr-076619	Oryza brachyantha	30.17	3.00e-71	264.00
IUUC-Ogl-077493	Oryza glaberrima	25.22	5.00e-35	144.00
IUUC-Oni-082991	Oryza nivara	27.78	2.00e-39	159.00
IUUC-Opu-083233	Oryza punctata	29.74	6.00e-66	246.00
IUUC-Oga-088578	Otolemur garnettii	96.70	0.00e+00	3164.00
IUUC-Oar-090247	Ovis aries	96.08	0.00e+00	3117.00
IUUC-Ptr-091266	Pan troglodytes	99.33	0.00e+00	3295.00
IUUC-Pan-092734	Papio anubis	99.01	0.00e+00	3420.00
IUUC-Pfo-096191	Poecilia formosa	72.48	0.00e+00	2057.00
IUUC-Pop-099185	Populus trichocarpa	35.42	1.00e-70	262.00
IUUC-Pca-101128	Procavia capensis	84.09	0.00e+00	2863.00
IUUC-Ppe-101849	Prunus persica	31.70	3.00e-75	277.00
IUUC-Pva-103058	Pteropus vampyrus	95.23	0.00e+00	1575.00
IUUC-Rno-106013	Rattus norvegicus	93.35	0.00e+00	3130.00
IUUC-Sha-107496	Sarcophilus harrisii	91.21	0.00e+00	3096.00
IUUC-Sly-111348	Solanum lycopersicum	31.50	1.00e-74	275.00
IUUC-Sar-113520	Sorex araneus	91.02	0.00e+00	1539.00
IUUC-Sbi-114195	Sorghum bicolor	30.08	6.00e-60	225.00
IUUC-Ssc-115461	Sus scrofa	92.81	0.00e+00	3146.00
IUUC-Tgu-116821	Taeniopygia guttata	86.13	0.00e+00	2932.00
IUUC-Tsy-119132	Tarsius syrichta	85.22	0.00e+00	2586.00
IUUC-Tca-121615	Theobroma cacao	30.35	5.00e-67	250.00
IUUC-Tae-125478	Triticum aestivum	31.56	2.00e-72	268.00
IUUC-Tur-126809	Triticum urartu	31.23	2.00e-70	262.00
IUUC-Tbe-127479	Tupaia belangeri	93.19	0.00e+00	1464.00
IUUC-Ttr-128427	Tursiops truncatus	90.94	0.00e+00	3059.00
IUUC-Vpa-130160	Vicugna pacos	93.37	0.00e+00	3046.00
IUUC-Vvi-131332	Vitis vinifera	31.68	4.00e-78	286.00
IUUC-Xtr-132717	Xenopus tropicalis	74.89	0.00e+00	2576.00
IUUC-Xma-134120	Xiphophorus maculatus	78.16	0.00e+00	1286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence