iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058423

Ensembl Protein ID

AES89203

UniProt Accession

G7JIM0; G7JIM0_MEDTR

Genbank Protein ID

AES89203.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g071130

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g071130	AES89203	AES89203

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-38	128.6	50	86
UBD/Beta-Prp	3.50e-76	257.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f ++ +l+vsG+dD +ikvW+++ +++l
   Q: 50   HDGPVRGVHFhNSqPLFVSGGDDYKIKVWNYKMHRCL 86
           99********9777****************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKMHRCLFTLLGHLDYIRTVQFHH 103
           67789999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...........................ktgkllrtltgg 178
           ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++++vs+slD+tvr+Wd+                             + + + l+g 
   Q: 104  ENPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDIVVSASLDQTVRVWDIgslkrkagppsddilrlsqmntdlfggVDAVVKYVLEG- 202
           **************************.*************************************************977766666666333333444466. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           h++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ ++t+ +++++++  ++ +++ 
   Q: 203  HDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDATKRTGIQTFRREHDRFWILST-HPEM 302
           ********************************777668**********************************************************.6666 PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n l++g  ds   ++kl++++p
   Q: 303  NLLAAG-HDSGMIVFKLERERP 323
           655555.689999999988765 PP

Organism

Medicago truncatula

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MFTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNY KMHRCLFTLL GHLDYIRTVQ FHHENPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTACGA AATTCGAGAC AAAAAGTAAC AGAGTGAAGG GATTGAGTTT CCACAGCAAG 60
AGACCATGGA TACTTGCGAG TCTTCACAGT GGTGTGATCC AGCTATGGGA CTATCGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

mtr:MTR_4g071130

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cme-027222	Cyanidioschyzon merolae	41.04	1.00e-145	510.00
IUUC-Gma-043585	Glycine max	91.75	0.00e+00	2240.00
IUUC-Lpe-051316	Leersia perrieri	77.22	0.00e+00	1944.00
IUUC-Mac-065398	Musa acuminata	73.34	0.00e+00	1818.00
IUUC-Olo-080466	Oryza longistaminata	83.60	0.00e+00	1477.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence