iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-11	42.1	3070	3107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvll 36
           gHtd vtcla      + +vsGs+Dgt  vWD+++++ +
   Q: 3070 GHTDAVTCLAAsaaY-NVIVSGSRDGTAIVWDMTRFTFV 3107
           8*******9776531.89**************9988765 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MNVMRKLRGA ASAGSVSGSS SGTSTANNSS PGSSRTDAGA PTAANGRNAE EALMDARVQV 60
SLTTLKKLFN EYTHPREPLS EQERDDKLYE MLPLFCKVFS SCPSNDMSEK FWDVVAFCQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGAGAAA ATTTGGTTCA TATTTTCATA CGTGAAACAA GATGTAAAAC GAGTGCATTT 60
AGGGCCCAAA ATAGTGAAAA CTCACACGGG AAACACAATG CTAGCGACGG ATAGCAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000409--BEACH_dom
IPR013320--ConA-like_dom
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF02138--Beach
PF01363--FYVE
PF14844--PH_BEACH
PF00400--WD40

SMART

SM01026--Beach
SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031594--C:neuromuscular junction
GO:0048786--C:presynaptic active zone
GO:0046872--F:metal ion binding
GO:0007420--P:brain development
GO:0022416--P:chaeta development
GO:0048749--P:compound eye development
GO:0048666--P:neuron development
GO:0046622--P:positive regulation of organ growth
GO:0031396--P:regulation of protein ubiquitination
GO:0050807--P:regulation of synapse organization

KEGG

dme:Dmel_CG14001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000317	Aegilops tauschii	41.88	3.00e-168	587.00
IUUC-Aml-002094	Ailuropoda melanoleuca	47.21	0.00e+00	2751.00
IUUC-Atr-002879	Amborella trichopoda	41.07	4.00e-168	586.00
IUUC-Apl-003581	Anas platyrhynchos	47.20	0.00e+00	2078.00
IUUC-Aca-005386	Anolis carolinensis	47.21	0.00e+00	2782.00
IUUC-Aly-006119	Arabidopsis lyrata	42.35	5.00e-166	579.00
IUUC-Ath-007689	Arabidopsis thaliana	45.43	2.00e-157	551.00
IUUC-Afu-009064	Aspergillus fumigatus	40.05	1.00e-163	571.00
IUUC-Ani-009310	Aspergillus nidulans	40.16	5.00e-161	562.00
IUUC-Aor-010079	Aspergillus oryzae	40.58	2.00e-162	566.00
IUUC-Ame-011607	Astyanax mexicanus	45.48	0.00e+00	2526.00
IUUC-Bta-012997	Bos taurus	47.26	0.00e+00	2736.00
IUUC-Bci-013784	Botrytis cinerea	39.19	3.00e-153	536.00
IUUC-Bdi-015031	Brachypodium distachyon	40.93	2.00e-168	587.00
IUUC-Bol-016599	Brassica oleracea	40.89	5.00e-163	569.00
IUUC-Bra-017709	Brassica rapa	40.77	4.00e-163	570.00
IUUC-Cja-019272	Callithrix jacchus	47.26	0.00e+00	2763.00
IUUC-Cfa-020073	Canis familiaris	47.47	0.00e+00	2761.00
IUUC-Cpo-021455	Cavia porcellus	46.84	0.00e+00	2721.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	38.46	2.00e-10	60.50
IUUC-Csa-023097	Chlorocebus sabaeus	47.53	0.00e+00	2777.00
IUUC-Cin-025176	Ciona intestinalis	37.59	2.00e-22	99.40
IUUC-Csv-026108	Ciona savignyi	35.35	6.00e-93	334.00
IUUC-Cgl-026670	Colletotrichum gloeosporioides	37.71	4.00e-130	459.00
IUUC-Dre-027703	Danio rerio	47.33	0.00e+00	2695.00
IUUC-Dno-029515	Dasypus novemcinctus	67.43	0.00e+00	681.00
IUUC-Dor-030567	Dipodomys ordii	47.43	0.00e+00	694.00
IUUC-Ete-032373	Echinops telfairi	54.24	0.00e+00	1045.00
IUUC-Eca-033575	Equus caballus	47.52	0.00e+00	2766.00
IUUC-Eeu-034853	Erinaceus europaeus	82.52	2.00e-107	384.00
IUUC-Fca-036304	Felis catus	47.19	0.00e+00	2722.00
IUUC-Fal-037019	Ficedula albicollis	47.52	0.00e+00	2770.00
IUUC-Fox-038015	Fusarium oxysporum	33.54	4.00e-139	488.00
IUUC-Fso-038249	Fusarium solani	37.31	2.00e-134	474.00
IUUC-Gmo-039503	Gadus morhua	46.05	0.00e+00	2600.00
IUUC-Ggr-039900	Gaeumannomyces graminis	39.54	9.00e-148	518.00
IUUC-Gga-041220	Gallus gallus	27.56	0.00e+00	735.00
IUUC-Gac-041618	Gasterosteus aculeatus	46.30	0.00e+00	2647.00
IUUC-Gma-043242	Glycine max	41.39	1.00e-161	564.00
IUUC-Ggo-044679	Gorilla gorilla	46.64	0.00e+00	2698.00
IUUC-Hsa-046586	Homo sapiens	47.67	0.00e+00	2778.00
IUUC-Hvu-047814	Hordeum vulgare	41.34	4.00e-169	590.00
IUUC-Itr-048396	Ictidomys tridecemlineatus	46.38	0.00e+00	2191.00
IUUC-Lch-049803	Latimeria chalumnae	33.50	0.00e+00	926.00
IUUC-Lpe-050828	Leersia perrieri	34.74	1.00e-171	598.00
IUUC-Loc-052434	Lepisosteus oculatus	47.85	0.00e+00	2789.00
IUUC-Lma-053017	Leptosphaeria maculans	35.29	2.00e-130	460.00
IUUC-Laf-054408	Loxodonta africana	47.59	0.00e+00	2765.00
IUUC-Mcc-055652	Macaca mulatta	47.62	0.00e+00	2778.00
IUUC-Meu-056743	Macropus eugenii	40.91	0.00e+00	1186.00
IUUC-Mor-057120	Magnaporthe oryzae	38.36	3.00e-148	520.00
IUUC-Mtr-058732	Medicago truncatula	35.32	3.00e-167	583.00
IUUC-Mla-058974	Melampsora laricipopulina	33.40	7.00e-137	482.00
IUUC-Mvi-060546	Microbotryum violaceum	31.86	9.00e-160	558.00
IUUC-Mmr-061760	Microcebus murinus	42.29	0.00e+00	1452.00
IUUC-Mdo-062645	Monodelphis domestica	47.12	0.00e+00	2739.00
IUUC-Mmu-063588	Mus musculus	47.34	0.00e+00	2776.00
IUUC-Mac-064551	Musa acuminata	38.34	4.00e-166	579.00
IUUC-Mpu-066073	Mustela putorius furo	47.33	0.00e+00	2756.00
IUUC-Mlu-067641	Myotis lucifugus	47.19	0.00e+00	2757.00
IUUC-Nfi-068471	Neosartorya fischeri	41.17	2.00e-164	573.00
IUUC-Nle-070009	Nomascus leucogenys	47.58	0.00e+00	2785.00
IUUC-Opr-070689	Ochotona princeps	41.17	0.00e+00	1218.00
IUUC-Ont-071427	Oreochromis niloticus	48.30	0.00e+00	1476.00
IUUC-Oan-073118	Ornithorhynchus anatinus	45.14	0.00e+00	2534.00
IUUC-Ocu-074702	Oryctolagus cuniculus	47.46	0.00e+00	2775.00
IUUC-Oba-075831	Oryza barthii	41.43	3.00e-169	590.00
IUUC-Obr-076728	Oryza brachyantha	41.43	2.00e-169	590.00
IUUC-Ogl-077922	Oryza glaberrima	41.43	4.00e-169	589.00
IUUC-Ogu-079001	Oryza glumaepatula	41.67	4.00e-169	589.00
IUUC-Oin-079929	Oryza indica	41.27	2.00e-157	548.00
IUUC-Olo-080662	Oryza longistaminata	41.43	1.00e-168	588.00
IUUC-Ome-081733	Oryza meridionalis	41.43	6.00e-169	589.00
IUUC-Oni-082641	Oryza nivara	41.18	9.00e-169	588.00
IUUC-Opu-083564	Oryza punctata	41.43	6.00e-169	589.00
IUUC-Oru-084403	Oryza rufipogon	41.43	4.00e-169	590.00
IUUC-Osa-085957	Oryza sativa	34.09	1.00e-45	176.00
IUUC-Ola-086856	Oryzias latipes	45.21	0.00e+00	2598.00
IUUC-Oga-088908	Otolemur garnettii	53.26	0.00e+00	1338.00
IUUC-Oar-089625	Ovis aries	47.15	0.00e+00	2717.00
IUUC-Ptr-091209	Pan troglodytes	47.61	0.00e+00	2784.00
IUUC-Pan-092751	Papio anubis	47.61	0.00e+00	2767.00
IUUC-Psi-092951	Pelodiscus sinensis	47.75	0.00e+00	2797.00
IUUC-Ppa-095361	Physcomitrella patens	35.07	0.00e+00	629.00
IUUC-Pfo-097102	Poecilia formosa	47.17	0.00e+00	2709.00
IUUC-Pab-098485	Pongo abelii	47.46	0.00e+00	2783.00
IUUC-Pop-099807	Populus trichocarpa	37.33	6.00e-168	585.00
IUUC-Pca-100146	Procavia capensis	61.81	0.00e+00	709.00
IUUC-Ppe-101277	Prunus persica	41.93	3.00e-168	587.00
IUUC-Pva-102502	Pteropus vampyrus	53.04	0.00e+00	1311.00
IUUC-Ptt-103873	Puccinia triticina	34.25	2.00e-88	321.00
IUUC-Rno-105592	Rattus norvegicus	47.25	0.00e+00	2752.00
IUUC-Sha-106751	Sarcophilus harrisii	48.18	0.00e+00	1690.00
IUUC-Sja-107759	Schizosaccharomyces japonicus	38.15	1.00e-142	501.00
IUUC-Spo-108108	Schizosaccharomyces pombe	38.08	2.00e-142	500.00
IUUC-Ssl-108524	Sclerotinia sclerotiorum	36.24	7.00e-153	533.00
IUUC-Smo-109190	Selaginella moellendorffii	41.90	1.00e-169	591.00
IUUC-Sit-110811	Setaria italica	41.10	4.00e-169	590.00
IUUC-Sly-110936	Solanum lycopersicum	35.67	3.00e-165	577.00
IUUC-Sar-113013	Sorex araneus	72.81	1.00e-151	531.00
IUUC-Sbi-114421	Sorghum bicolor	41.01	1.00e-169	591.00
IUUC-Sre-115137	Sporisorium reilianum	33.62	3.00e-138	486.00
IUUC-Ssc-116100	Sus scrofa	47.07	0.00e+00	2728.00
IUUC-Tgu-117182	Taeniopygia guttata	47.38	0.00e+00	2771.00
IUUC-Tru-117859	Takifugu rubripes	42.21	0.00e+00	1639.00
IUUC-Tsy-119315	Tarsius syrichta	48.42	0.00e+00	1717.00
IUUC-Tni-120784	Tetraodon nigroviridis	41.95	0.00e+00	1608.00
IUUC-Tca-121423	Theobroma cacao	36.27	1.00e-163	571.00
IUUC-Tre-121988	Trichoderma reesei	38.57	6.00e-143	502.00
IUUC-Tvi-122476	Trichoderma virens	38.71	4.00e-142	499.00
IUUC-Tur-126221	Triticum urartu	41.53	3.00e-168	586.00
IUUC-Tme-126944	Tuber melanosporum	39.90	8.00e-157	548.00
IUUC-Tbe-127827	Tupaia belangeri	51.95	0.00e+00	1179.00
IUUC-Ttr-128368	Tursiops truncatus	47.21	0.00e+00	2742.00
IUUC-Vda-129813	Verticillium dahliae	33.03	1.00e-140	494.00
IUUC-Vpa-130252	Vicugna pacos	48.18	0.00e+00	1947.00
IUUC-Vvi-131663	Vitis vinifera	37.82	5.00e-170	592.00
IUUC-Xtr-132689	Xenopus tropicalis	47.39	0.00e+00	2784.00
IUUC-Xma-133273	Xiphophorus maculatus	44.96	0.00e+00	2256.00
IUUC-Zma-135580	Zea mays	41.29	5.00e-168	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence