iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053820

UUCD1 version

UUC-LoA-00693

Ensembl Protein ID

ENSLAFP00000026935.1

UniProt Accession

G3UGH7; G3UGH7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005423.2	ENSLAFT00000005422.2	ENSLAFP00000004546.2
ENSLAFG00000005423.2	ENSLAFT00000035687.1	ENSLAFP00000018952.1
ENSLAFG00000005423.2	ENSLAFT00000026038.1	ENSLAFP00000026935.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.00e-09	37.2	103	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 103  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 142
           **********999999*************......**********7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

QGSQQPPGSP LSREEGEAPP PAPAPESRRR SRRVRLRGSC RHRPSFLSRR ELATSAPAGS 60
APASSGIMAS AAKEFKMDNF SPKAGTSKLQ QTVPADASPD SKCPICLDRF DNVSYLDRCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCGC AGCAGCCGCC AGGGTCTCCG CTGTCTCGCG AGGAGGGTGA AGCGCCCCCG 60
CCCGCTCCGG CTCCTGAGAG TAGGCGGAGA AGTCGCCGGG TACGCCTTCG CGGGTCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	56.20
IUUC-Aml-002240	Ailuropoda melanoleuca	89.98	0.00e+00	920.00
IUUC-Atr-002964	Amborella trichopoda	32.63	5.00e-11	61.20
IUUC-Apl-003666	Anas platyrhynchos	64.47	2.00e-143	503.00
IUUC-Aca-005305	Anolis carolinensis	63.24	1.00e-149	523.00
IUUC-Aly-005926	Arabidopsis lyrata	45.76	1.00e-10	60.50
IUUC-Ath-007668	Arabidopsis thaliana	23.79	1.00e-10	60.10
IUUC-Ame-011109	Astyanax mexicanus	53.54	1.00e-113	404.00
IUUC-Bta-012637	Bos taurus	90.42	0.00e+00	906.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	63.20
IUUC-Bol-015115	Brassica oleracea	29.29	1.00e-08	53.50
IUUC-Bra-017451	Brassica rapa	31.25	2.00e-08	52.40
IUUC-Cel-018658	Caenorhabditis elegans	27.50	1.00e-06	48.50
IUUC-Cja-019105	Callithrix jacchus	92.69	0.00e+00	952.00
IUUC-Cfa-021203	Canis familiaris	90.65	0.00e+00	902.00
IUUC-Cpo-022335	Cavia porcellus	84.04	0.00e+00	836.00
IUUC-Csa-023870	Chlorocebus sabaeus	92.19	0.00e+00	952.00
IUUC-Cho-024870	Choloepus hoffmanni	91.41	0.00e+00	877.00
IUUC-Dre-027535	Danio rerio	49.57	7.00e-118	418.00
IUUC-Dno-028963	Dasypus novemcinctus	90.82	0.00e+00	862.00
IUUC-Dor-030239	Dipodomys ordii	87.93	0.00e+00	781.00
IUUC-Dme-031941	Drosophila melanogaster	43.56	1.00e-19	92.40
IUUC-Ete-032300	Echinops telfairi	86.73	0.00e+00	1181.00
IUUC-Eca-033690	Equus caballus	92.94	0.00e+00	896.00
IUUC-Eeu-035257	Erinaceus europaeus	86.08	0.00e+00	861.00
IUUC-Fca-036383	Felis catus	89.43	0.00e+00	899.00
IUUC-Fal-037209	Ficedula albicollis	69.15	5.00e-164	571.00
IUUC-Gmo-039416	Gadus morhua	52.46	7.00e-119	420.00
IUUC-Gga-041267	Gallus gallus	69.44	7.00e-174	604.00
IUUC-Gac-042227	Gasterosteus aculeatus	50.73	1.00e-116	412.00
IUUC-Gma-042777	Glycine max	42.86	6.00e-08	51.20
IUUC-Ggo-044445	Gorilla gorilla	92.36	0.00e+00	949.00
IUUC-Hsa-045844	Homo sapiens	92.53	0.00e+00	951.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	5.00e-11	58.50
IUUC-Itr-048818	Ictidomys tridecemlineatus	90.32	0.00e+00	924.00
IUUC-Lch-050031	Latimeria chalumnae	66.00	1.00e-167	583.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	58.01	2.00e-141	496.00
IUUC-Mcc-054800	Macaca mulatta	92.20	0.00e+00	954.00
IUUC-Meu-056806	Macropus eugenii	72.67	0.00e+00	632.00
IUUC-Mtr-058378	Medicago truncatula	45.07	1.00e-11	63.50
IUUC-Mla-059017	Melampsora laricipopulina	36.07	3.00e-09	55.80
IUUC-Mga-060049	Meleagris gallopavo	32.56	2.00e-08	53.50
IUUC-Mvi-060417	Microbotryum violaceum	25.09	2.00e-17	84.30
IUUC-Mmr-061481	Microcebus murinus	91.68	0.00e+00	904.00
IUUC-Mdo-062219	Monodelphis domestica	78.15	4.00e-110	392.00
IUUC-Mmu-064138	Mus musculus	86.96	0.00e+00	810.00
IUUC-Mac-064635	Musa acuminata	34.09	7.00e-11	59.70
IUUC-Mlu-067088	Myotis lucifugus	90.34	0.00e+00	905.00
IUUC-Nle-069862	Nomascus leucogenys	92.18	0.00e+00	962.00
IUUC-Opr-071076	Ochotona princeps	91.30	0.00e+00	812.00
IUUC-Ont-072225	Oreochromis niloticus	52.38	9.00e-111	394.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.83	3.00e-157	548.00
IUUC-Ocu-074826	Oryctolagus cuniculus	90.31	0.00e+00	914.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.50
IUUC-Obr-076084	Oryza brachyantha	36.23	3.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.50
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	60.10
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.50
IUUC-Opu-083698	Oryza punctata	36.62	6.00e-10	58.20
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	54.40	2.00e-108	385.00
IUUC-Oga-088059	Otolemur garnettii	88.44	0.00e+00	912.00
IUUC-Oar-089592	Ovis aries	89.03	0.00e+00	877.00
IUUC-Ptr-091233	Pan troglodytes	92.36	0.00e+00	950.00
IUUC-Pan-092743	Papio anubis	92.36	0.00e+00	955.00
IUUC-Psi-093669	Pelodiscus sinensis	58.64	0.00e+00	853.00
IUUC-Ppa-095668	Physcomitrella patens	28.08	8.00e-23	101.00
IUUC-Pfo-096706	Poecilia formosa	52.78	7.00e-105	374.00
IUUC-Pop-099119	Populus trichocarpa	24.35	1.00e-12	66.60
IUUC-Pca-100967	Procavia capensis	94.05	0.00e+00	850.00
IUUC-Ppe-101922	Prunus persica	37.93	1.00e-08	53.10
IUUC-Pva-102982	Pteropus vampyrus	93.21	0.00e+00	915.00
IUUC-Pgr-103551	Puccinia graminis	38.46	7.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	32.39	3.00e-07	48.50
IUUC-Rno-105730	Rattus norvegicus	85.96	0.00e+00	780.00
IUUC-Sha-106588	Sarcophilus harrisii	68.83	4.00e-180	625.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.70
IUUC-Smo-109039	Selaginella moellendorffii	24.39	7.00e-19	88.20
IUUC-Stu-112898	Solanum tuberosum	42.37	1.00e-08	55.80
IUUC-Sar-113622	Sorex araneus	88.95	1.00e-161	563.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	92.37	0.00e+00	858.00
IUUC-Tgu-117180	Taeniopygia guttata	66.46	1.00e-170	593.00
IUUC-Tru-118393	Takifugu rubripes	53.90	4.00e-119	422.00
IUUC-Tsy-119408	Tarsius syrichta	90.46	0.00e+00	891.00
IUUC-Tni-120664	Tetraodon nigroviridis	55.97	9.00e-118	417.00
IUUC-Tca-121712	Theobroma cacao	27.62	1.00e-18	87.00
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.50
IUUC-Tbe-127301	Tupaia belangeri	82.17	0.00e+00	793.00
IUUC-Ttr-128204	Tursiops truncatus	93.26	0.00e+00	940.00
IUUC-Uma-129420	Ustilago maydis	43.06	8.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	92.87	0.00e+00	900.00
IUUC-Vvi-131157	Vitis vinifera	25.50	5.00e-17	81.60
IUUC-Xtr-132845	Xenopus tropicalis	66.82	2.00e-171	595.00
IUUC-Xma-133439	Xiphophorus maculatus	51.84	1.00e-107	384.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	4.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence