iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010266

Ensembl Protein ID

CADATEAP00008859

UniProt Accession

Q0CW30; ATG18_ASPTN

Genbank Protein ID

EAU37066.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

CH476596

Gene Name

ATEG_02104; atg18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00008859	CADATEAT00008859	CADATEAP00008859

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-08	32.1	186	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++  c+ + sd tl++++sd gt i+v+++ +g++l
   Q: 186  HRSPLACITLnSDgTLIATASDKGTiIRVFSVPDGHKL 223
           999********999***********999****999876 PP

Organism

Aspergillus terreus

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MAMNFVTFNQ DYSYLAVATS KGFRIFTTDP FAKSYETKEG NIAIIEMLFS TSLVALILSP 60
RRLQITNTKR QSTICELTFP TTVLAVKLNR KRLVIVLEDQ IYLYDIQTMK LLYTIETSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAATGA ACTTCGTCAC GTTCAACCAG GACTACAGCT ATCTGGCTGT AGGTAAGAAT 60
TTTCCTTCTG CTGTGCGATG ATTCTGGGAT ATCTCTTAAC TTGGACCAGC CACCTCGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	31.74	2.00e-48	184.00
IUUC-Aml-001842	Ailuropoda melanoleuca	34.89	4.00e-60	223.00
IUUC-Atr-002710	Amborella trichopoda	31.41	9.00e-43	165.00
IUUC-Apl-003390	Anas platyrhynchos	34.15	2.00e-60	224.00
IUUC-Aca-004975	Anolis carolinensis	35.73	3.00e-68	250.00
IUUC-Aly-006355	Arabidopsis lyrata	31.63	1.00e-42	165.00
IUUC-Ath-007423	Arabidopsis thaliana	31.63	7.00e-43	166.00
IUUC-Ago-007948	Ashbya gossypii	54.67	1.00e-47	182.00
IUUC-Acl-008148	Aspergillus clavatus	88.49	0.00e+00	706.00
IUUC-Afl-008562	Aspergillus flavus	88.89	0.00e+00	676.00
IUUC-Afu-008936	Aspergillus fumigatus	87.89	0.00e+00	698.00
IUUC-Ani-009254	Aspergillus nidulans	87.20	0.00e+00	696.00
IUUC-Ang-009798	Aspergillus niger	88.43	0.00e+00	698.00
IUUC-Aor-010066	Aspergillus oryzae	88.89	0.00e+00	676.00
IUUC-Ame-010727	Astyanax mexicanus	35.97	2.00e-67	247.00
IUUC-Bta-012655	Bos taurus	34.77	5.00e-64	236.00
IUUC-Bci-013627	Botrytis cinerea	60.10	9.00e-135	471.00
IUUC-Bdi-014739	Brachypodium distachyon	30.55	6.00e-48	182.00
IUUC-Bol-015492	Brassica oleracea	29.85	8.00e-46	175.00
IUUC-Bra-017319	Brassica rapa	33.83	1.00e-36	145.00
IUUC-Cel-018503	Caenorhabditis elegans	32.56	5.00e-51	192.00
IUUC-Cja-018829	Callithrix jacchus	43.87	1.00e-54	205.00
IUUC-Cfa-020858	Canis familiaris	41.11	2.00e-56	211.00
IUUC-Cpo-022235	Cavia porcellus	43.73	3.00e-59	220.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	33.11	6.00e-41	159.00
IUUC-Csa-023963	Chlorocebus sabaeus	43.08	1.00e-55	209.00
IUUC-Cho-024328	Choloepus hoffmanni	46.22	1.00e-54	205.00
IUUC-Cin-025343	Ciona intestinalis	35.46	1.00e-59	222.00
IUUC-Csv-025920	Ciona savignyi	37.05	5.00e-66	243.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	69.93	2.00e-55	207.00
IUUC-Cne-026947	Cryptococcus neoformans	52.26	1.00e-104	370.00
IUUC-Dre-027490	Danio rerio	35.49	1.00e-65	242.00
IUUC-Dno-030057	Dasypus novemcinctus	34.89	4.00e-61	226.00
IUUC-Dor-030472	Dipodomys ordii	43.70	4.00e-54	203.00
IUUC-Dse-031215	Dothistroma septosporum	51.17	5.00e-122	429.00
IUUC-Dme-031881	Drosophila melanogaster	34.41	6.00e-32	129.00
IUUC-Ete-032276	Echinops telfairi	33.65	2.00e-52	197.00
IUUC-Eca-034362	Equus caballus	34.64	5.00e-61	226.00
IUUC-Eeu-034479	Erinaceus europaeus	35.68	7.00e-25	105.00
IUUC-Fca-036230	Felis catus	34.73	1.00e-60	225.00
IUUC-Fal-036782	Ficedula albicollis	34.64	1.00e-61	228.00
IUUC-Fox-037797	Fusarium oxysporum	57.08	2.00e-125	440.00
IUUC-Fso-038174	Fusarium solani	57.11	1.00e-121	427.00
IUUC-Gmo-039706	Gadus morhua	34.53	5.00e-61	226.00
IUUC-Ggr-040113	Gaeumannomyces graminis	70.77	7.00e-105	372.00
IUUC-Gga-040690	Gallus gallus	34.53	2.00e-63	234.00
IUUC-Gac-041360	Gasterosteus aculeatus	36.45	2.00e-69	254.00
IUUC-Gma-043876	Glycine max	44.00	3.00e-57	213.00
IUUC-Ggo-045610	Gorilla gorilla	30.19	5.00e-33	133.00
IUUC-Hsa-046782	Homo sapiens	43.48	4.00e-56	210.00
IUUC-Hvu-047851	Hordeum vulgare	31.74	1.00e-48	185.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	43.48	2.00e-56	211.00
IUUC-Kpa-049378	Komagataella pastoris	46.38	2.00e-75	274.00
IUUC-Lch-050413	Latimeria chalumnae	32.19	5.00e-58	216.00
IUUC-Lpe-051205	Leersia perrieri	31.58	5.00e-49	186.00
IUUC-Loc-052379	Lepisosteus oculatus	35.29	2.00e-40	157.00
IUUC-Lma-052948	Leptosphaeria maculans	62.50	3.00e-155	539.00
IUUC-Laf-054007	Loxodonta africana	34.77	7.00e-64	236.00
IUUC-Mcc-055304	Macaca mulatta	35.47	2.00e-39	154.00
IUUC-Meu-056020	Macropus eugenii	31.56	8.00e-33	132.00
IUUC-Mor-057125	Magnaporthe oryzae	56.12	3.00e-135	473.00
IUUC-Mpo-057416	Magnaporthe poae	28.21	1.00e-29	122.00
IUUC-Mtr-058536	Medicago truncatula	32.78	2.00e-47	181.00
IUUC-Mla-058885	Melampsora laricipopulina	22.64	2.00e-13	67.80
IUUC-Mga-059795	Meleagris gallopavo	34.40	1.00e-61	228.00
IUUC-Mvi-060219	Microbotryum violaceum	50.71	2.00e-103	367.00
IUUC-Mmr-061096	Microcebus murinus	41.70	9.00e-58	215.00
IUUC-Mdo-062881	Monodelphis domestica	34.69	1.00e-63	234.00
IUUC-Mmu-063787	Mus musculus	35.01	5.00e-63	233.00
IUUC-Mac-064838	Musa acuminata	31.22	4.00e-49	186.00
IUUC-Mpu-066019	Mustela putorius furo	42.50	3.00e-57	214.00
IUUC-Mlu-068016	Myotis lucifugus	36.45	2.00e-68	251.00
IUUC-Nfi-068424	Neosartorya fischeri	89.86	0.00e+00	706.00
IUUC-Ncr-068833	Neurospora crassa	55.53	8.00e-131	458.00
IUUC-Nle-069047	Nomascus leucogenys	35.11	3.00e-43	167.00
IUUC-Opr-070933	Ochotona princeps	46.47	5.00e-39	153.00
IUUC-Ont-072495	Oreochromis niloticus	36.69	8.00e-70	255.00
IUUC-Oan-073084	Ornithorhynchus anatinus	35.01	3.00e-59	220.00
IUUC-Ocu-074689	Oryctolagus cuniculus	44.11	6.00e-60	223.00
IUUC-Oba-075601	Oryza barthii	39.86	5.00e-41	159.00
IUUC-Obr-076476	Oryza brachyantha	31.10	1.00e-48	185.00
IUUC-Ogl-077630	Oryza glaberrima	31.58	4.00e-49	186.00
IUUC-Ogu-078089	Oryza glumaepatula	39.86	4.00e-41	160.00
IUUC-Oin-079071	Oryza indica	39.86	4.00e-41	160.00
IUUC-Olo-080657	Oryza longistaminata	32.61	7.00e-49	187.00
IUUC-Ome-081702	Oryza meridionalis	31.10	8.00e-46	176.00
IUUC-Oni-083063	Oryza nivara	39.86	4.00e-41	160.00
IUUC-Opu-083460	Oryza punctata	31.41	6.00e-48	184.00
IUUC-Oru-084845	Oryza rufipogon	39.71	5.00e-41	159.00
IUUC-Osa-086113	Oryza sativa	39.86	4.00e-41	160.00
IUUC-Ola-086628	Oryzias latipes	35.46	9.00e-44	168.00
IUUC-Olu-087808	Ostreococcus lucimarinus	31.97	1.00e-41	161.00
IUUC-Oga-088894	Otolemur garnettii	43.48	2.00e-56	211.00
IUUC-Oar-089850	Ovis aries	34.15	1.00e-60	224.00
IUUC-Ptr-090456	Pan troglodytes	43.48	3.00e-56	210.00
IUUC-Pan-092111	Papio anubis	43.73	1.00e-59	221.00
IUUC-Psi-094095	Pelodiscus sinensis	34.64	4.00e-62	230.00
IUUC-Pma-094403	Petromyzon marinus	29.96	3.00e-31	127.00
IUUC-Pno-095015	Phaeosphaeria nodorum	63.33	8.00e-147	511.00
IUUC-Ppa-095480	Physcomitrella patens	33.09	4.00e-45	173.00
IUUC-Pfo-096987	Poecilia formosa	36.45	2.00e-68	251.00
IUUC-Pab-097754	Pongo abelii	43.48	7.00e-56	209.00
IUUC-Pop-099157	Populus trichocarpa	29.57	5.00e-42	163.00
IUUC-Pca-100176	Procavia capensis	28.52	7.00e-26	109.00
IUUC-Ppe-101799	Prunus persica	32.62	5.00e-41	159.00
IUUC-Pva-103047	Pteropus vampyrus	33.56	9.00e-61	225.00
IUUC-Pgr-103258	Puccinia graminis	23.53	5.00e-12	64.30
IUUC-Ptt-103915	Puccinia triticina	24.03	1.00e-17	83.20
IUUC-Pte-104139	Pyrenophora teres	63.16	3.00e-146	509.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	62.50	3.00e-145	506.00
IUUC-Rno-105990	Rattus norvegicus	35.01	2.00e-63	234.00
IUUC-Sce-106327	Saccharomyces cerevisiae	39.07	4.00e-85	306.00
IUUC-Sha-106581	Sarcophilus harrisii	34.15	5.00e-60	223.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	39.56	5.00e-78	282.00
IUUC-Spo-108068	Schizosaccharomyces pombe	40.99	6.00e-77	279.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	60.10	6.00e-146	508.00
IUUC-Smo-109446	Selaginella moellendorffii	32.93	1.00e-54	205.00
IUUC-Sit-110095	Setaria italica	31.34	7.00e-47	179.00
IUUC-Sly-111030	Solanum lycopersicum	31.48	2.00e-47	181.00
IUUC-Stu-111954	Solanum tuberosum	28.30	3.00e-36	144.00
IUUC-Sar-113276	Sorex araneus	36.22	9.00e-26	108.00
IUUC-Sbi-114020	Sorghum bicolor	31.34	2.00e-47	181.00
IUUC-Sre-115219	Sporisorium reilianum	50.57	4.00e-105	373.00
IUUC-Ssc-116360	Sus scrofa	34.77	9.00e-64	235.00
IUUC-Tgu-116951	Taeniopygia guttata	34.15	2.00e-60	224.00
IUUC-Tru-117889	Takifugu rubripes	34.95	3.00e-66	244.00
IUUC-Tsy-119533	Tarsius syrichta	35.71	9.00e-19	84.70
IUUC-Tni-119729	Tetraodon nigroviridis	35.00	4.00e-36	143.00
IUUC-Tca-121732	Theobroma cacao	31.65	3.00e-38	150.00
IUUC-Tre-121895	Trichoderma reesei	58.72	4.00e-138	482.00
IUUC-Tvi-122311	Trichoderma virens	57.69	2.00e-138	483.00
IUUC-Tae-124901	Triticum aestivum	31.74	2.00e-48	184.00
IUUC-Tur-126757	Triticum urartu	31.26	4.00e-47	180.00
IUUC-Ttr-128940	Tursiops truncatus	35.37	3.00e-35	140.00
IUUC-Uma-129438	Ustilago maydis	50.12	3.00e-95	340.00
IUUC-Vda-129782	Verticillium dahliae	53.87	5.00e-94	336.00
IUUC-Vvi-131674	Vitis vinifera	31.34	2.00e-48	184.00
IUUC-Xtr-131806	Xenopus tropicalis	34.75	4.00e-43	166.00
IUUC-Xma-133370	Xiphophorus maculatus	36.45	2.00e-68	251.00
IUUC-Yli-134337	Yarrowia lipolytica	48.62	2.00e-100	357.00
IUUC-Zma-135902	Zea mays	30.32	6.00e-39	153.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence