iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000004455.6	ENSGALT00000060144.1	ENSGALP00000051381.1
ENSGALG00000004455.6	ENSGALT00000007092.6	ENSGALP00000007080.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-69	234.5	1895	2240

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1895 VGLTNLGATCYLASTIQQLYMIPEARQAIFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1974
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1975 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2033
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2034 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2115
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                +  k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2116 MTPYTEDflmgkndrkegfkedgEYLKETESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSTQLAS 2202
           *******999998888888888755566669**************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2203 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2240
           7779********************************96 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MCESCAELLE VLNEISDVEG ADGLQLRKEH VLKIFAYINS WTQRQCLCCF KEYKHLEIFN 60
QVVCTLINLV IAEVQALRDQ LCKHCTINID STWQDHSNRA DEPLNVERDS HEEENGERQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACAATGTG TGAGAGCTGC GCCGAGCTGC TGGAGGTGTT AAACGAGAGT AAGTGCGGCC 60
GCCCTCTCTA CTGCCCTTCT CCGGCAGTCC TCGCCCTGCG CCGGGCTCCC GCACCCCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	92.37	0.00e+00	6495.00
IUUC-Apl-003284	Anas platyrhynchos	96.41	0.00e+00	6461.00
IUUC-Aca-004415	Anolis carolinensis	93.33	0.00e+00	6554.00
IUUC-Acl-008140	Aspergillus clavatus	28.87	2.00e-64	242.00
IUUC-Afl-008381	Aspergillus flavus	29.20	2.00e-64	242.00
IUUC-Afu-008857	Aspergillus fumigatus	28.64	1.00e-65	246.00
IUUC-Ani-009257	Aspergillus nidulans	27.42	6.00e-56	214.00
IUUC-Ang-009759	Aspergillus niger	27.73	6.00e-63	237.00
IUUC-Aor-009931	Aspergillus oryzae	29.20	2.00e-64	242.00
IUUC-Ate-010246	Aspergillus terreus	29.72	1.00e-53	206.00
IUUC-Ame-011219	Astyanax mexicanus	63.29	0.00e+00	2455.00
IUUC-Bgr-012195	Blumeria graminis	26.90	9.00e-65	243.00
IUUC-Bta-012989	Bos taurus	92.08	0.00e+00	6442.00
IUUC-Bci-013798	Botrytis cinerea	33.17	5.00e-58	220.00
IUUC-Cja-018974	Callithrix jacchus	87.65	0.00e+00	733.00
IUUC-Cfa-021214	Canis familiaris	92.42	0.00e+00	6502.00
IUUC-Cpo-021912	Cavia porcellus	93.17	0.00e+00	4538.00
IUUC-Csa-023658	Chlorocebus sabaeus	92.15	0.00e+00	6488.00
IUUC-Cho-024971	Choloepus hoffmanni	78.58	0.00e+00	3051.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	26.81	3.00e-63	238.00
IUUC-Dre-027428	Danio rerio	84.22	0.00e+00	4642.00
IUUC-Dno-029690	Dasypus novemcinctus	91.52	0.00e+00	6351.00
IUUC-Dor-030817	Dipodomys ordii	91.07	0.00e+00	1449.00
IUUC-Dse-031423	Dothistroma septosporum	25.78	1.00e-36	149.00
IUUC-Dme-032102	Drosophila melanogaster	54.13	0.00e+00	852.00
IUUC-Ete-032552	Echinops telfairi	87.89	0.00e+00	2867.00
IUUC-Eca-033457	Equus caballus	92.90	0.00e+00	6266.00
IUUC-Eeu-035118	Erinaceus europaeus	87.93	0.00e+00	2937.00
IUUC-Fca-036213	Felis catus	90.93	0.00e+00	4872.00
IUUC-Fal-037643	Ficedula albicollis	95.94	0.00e+00	6671.00
IUUC-Fox-037971	Fusarium oxysporum	27.21	2.00e-61	231.00
IUUC-Fso-038108	Fusarium solani	26.57	2.00e-58	222.00
IUUC-Ggr-040075	Gaeumannomyces graminis	31.92	2.00e-60	228.00
IUUC-Gac-042024	Gasterosteus aculeatus	91.00	0.00e+00	4325.00
IUUC-Ggo-044924	Gorilla gorilla	88.85	0.00e+00	5979.00
IUUC-Hsa-046913	Homo sapiens	92.17	0.00e+00	6521.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	92.14	0.00e+00	6481.00
IUUC-Lch-049675	Latimeria chalumnae	87.17	0.00e+00	4940.00
IUUC-Loc-052832	Lepisosteus oculatus	86.46	0.00e+00	6009.00
IUUC-Lma-053130	Leptosphaeria maculans	27.47	5.00e-59	224.00
IUUC-Laf-054169	Loxodonta africana	91.47	0.00e+00	6471.00
IUUC-Mcc-055847	Macaca mulatta	91.12	0.00e+00	6380.00
IUUC-Meu-056327	Macropus eugenii	81.58	0.00e+00	1552.00
IUUC-Mor-057152	Magnaporthe oryzae	28.17	1.00e-61	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.43	4.00e-59	224.00
IUUC-Mmr-060780	Microcebus murinus	92.40	0.00e+00	6516.00
IUUC-Mdo-062308	Monodelphis domestica	91.30	0.00e+00	6129.00
IUUC-Mmu-063457	Mus musculus	90.87	0.00e+00	6444.00
IUUC-Mpu-066917	Mustela putorius furo	90.17	0.00e+00	6281.00
IUUC-Mlu-067696	Myotis lucifugus	92.11	0.00e+00	6452.00
IUUC-Nfi-068259	Neosartorya fischeri	27.88	4.00e-65	244.00
IUUC-Ncr-068911	Neurospora crassa	25.56	1.00e-59	226.00
IUUC-Nle-069586	Nomascus leucogenys	92.03	0.00e+00	6506.00
IUUC-Opr-070447	Ochotona princeps	87.06	0.00e+00	2743.00
IUUC-Ont-072396	Oreochromis niloticus	80.98	0.00e+00	5486.00
IUUC-Oan-073147	Ornithorhynchus anatinus	93.34	0.00e+00	6541.00
IUUC-Ocu-074324	Oryctolagus cuniculus	91.92	0.00e+00	6455.00
IUUC-Ola-086312	Oryzias latipes	81.58	0.00e+00	5299.00
IUUC-Oga-088878	Otolemur garnettii	92.11	0.00e+00	6488.00
IUUC-Oar-089919	Ovis aries	92.08	0.00e+00	6433.00
IUUC-Ptr-090713	Pan troglodytes	92.66	0.00e+00	6002.00
IUUC-Pan-091957	Papio anubis	93.20	0.00e+00	4928.00
IUUC-Psi-093240	Pelodiscus sinensis	94.45	0.00e+00	6607.00
IUUC-Pma-094469	Petromyzon marinus	71.93	0.00e+00	4081.00
IUUC-Pno-095059	Phaeosphaeria nodorum	28.43	3.00e-55	211.00
IUUC-Pfo-097159	Poecilia formosa	78.89	0.00e+00	5558.00
IUUC-Pab-098003	Pongo abelii	92.13	0.00e+00	6193.00
IUUC-Pca-100799	Procavia capensis	95.50	0.00e+00	1466.00
IUUC-Pva-103226	Pteropus vampyrus	87.71	0.00e+00	6093.00
IUUC-Pte-104235	Pyrenophora teres	32.66	3.00e-58	221.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.46	3.00e-59	224.00
IUUC-Rno-105389	Rattus norvegicus	91.21	0.00e+00	5336.00
IUUC-Sha-106979	Sarcophilus harrisii	93.05	0.00e+00	6519.00
IUUC-Sar-113444	Sorex araneus	85.92	0.00e+00	5686.00
IUUC-Ssc-115815	Sus scrofa	93.22	0.00e+00	5429.00
IUUC-Tgu-117470	Taeniopygia guttata	95.50	0.00e+00	6358.00
IUUC-Tru-118543	Takifugu rubripes	81.63	0.00e+00	5376.00
IUUC-Tsy-119081	Tarsius syrichta	84.16	0.00e+00	4700.00
IUUC-Tni-120294	Tetraodon nigroviridis	82.00	9.00e-163	565.00
IUUC-Tre-122057	Trichoderma reesei	32.87	1.00e-60	229.00
IUUC-Tvi-122570	Trichoderma virens	35.62	8.00e-59	223.00
IUUC-Tme-127154	Tuber melanosporum	28.00	2.00e-60	227.00
IUUC-Tbe-127801	Tupaia belangeri	92.51	0.00e+00	2239.00
IUUC-Ttr-129262	Tursiops truncatus	88.29	0.00e+00	6150.00
IUUC-Vda-129686	Verticillium dahliae	28.38	4.00e-60	228.00
IUUC-Vpa-130484	Vicugna pacos	88.41	0.00e+00	6078.00
IUUC-Xtr-131769	Xenopus tropicalis	85.91	0.00e+00	6078.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence