iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062308

UUCD1 version

UUC-MoD-01146

Ensembl Protein ID

ENSMODP00000003339.2

UniProt Accession

F6Z6U4; F6Z6U4_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002734.3	ENSMODT00000003408.2	ENSMODP00000003339.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-69	234.9	1714	2059

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e+++       +++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1714 VGLTNLGATCYLASTIQQLYMIPEARQAIFTaKYSEDIK-------HKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1793
           6*****************************945555554.......568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1794 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 1852
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 1853 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 1934
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + ek++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 1935 MTPYTEDflmgkcdrkegfkeevDHEKETESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2021
           **************99999999955566669**************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2022 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2059
           7779********************************96 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

QDISAQESNI LGAFCDMNDV EVPLHLLRYV CLFCGKNGLS LMKDCFEYGT PETLPFLIAH 60
AFITVVSNIR IWLHIPAVMQ HIIPFRTYVI SFYCMLSSAK DVKLYYSKNN DVLPWSLCYY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGATATTT CAGCTCAAGA AAGCAATATA TTAGGGGCGT TCTGTGATAT GAATGTAAGT 60
AGTGTGCATT TTTTATTTTA AAATTTTTGA CATTTAAGTC CTTTCTTAAT TATGTATTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	92.82	0.00e+00	6166.00
IUUC-Apl-003284	Anas platyrhynchos	93.36	0.00e+00	6159.00
IUUC-Aca-004415	Anolis carolinensis	91.66	0.00e+00	6064.00
IUUC-Acl-008140	Aspergillus clavatus	29.04	2.00e-63	239.00
IUUC-Afl-008381	Aspergillus flavus	28.71	4.00e-63	238.00
IUUC-Afu-008857	Aspergillus fumigatus	28.48	5.00e-64	241.00
IUUC-Ani-009257	Aspergillus nidulans	26.19	7.00e-56	214.00
IUUC-Ang-009759	Aspergillus niger	28.04	8.00e-63	237.00
IUUC-Aor-009931	Aspergillus oryzae	28.71	4.00e-63	238.00
IUUC-Ame-011219	Astyanax mexicanus	63.95	0.00e+00	2480.00
IUUC-Bgr-012195	Blumeria graminis	27.11	5.00e-67	251.00
IUUC-Bta-012989	Bos taurus	92.50	0.00e+00	6135.00
IUUC-Bci-013798	Botrytis cinerea	32.68	1.00e-57	219.00
IUUC-Cja-018974	Callithrix jacchus	90.82	0.00e+00	761.00
IUUC-Cfa-021214	Canis familiaris	92.91	0.00e+00	6177.00
IUUC-Cpo-021912	Cavia porcellus	91.63	0.00e+00	4135.00
IUUC-Csa-023658	Chlorocebus sabaeus	92.29	0.00e+00	6111.00
IUUC-Cho-024971	Choloepus hoffmanni	81.22	0.00e+00	3103.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	29.01	3.00e-63	238.00
IUUC-Dre-027428	Danio rerio	85.39	0.00e+00	4668.00
IUUC-Dno-029690	Dasypus novemcinctus	92.13	0.00e+00	6082.00
IUUC-Dor-030817	Dipodomys ordii	85.87	0.00e+00	2077.00
IUUC-Dse-031423	Dothistroma septosporum	26.65	8.00e-36	147.00
IUUC-Dme-032102	Drosophila melanogaster	54.75	0.00e+00	855.00
IUUC-Ete-032552	Echinops telfairi	90.24	0.00e+00	2906.00
IUUC-Eca-033457	Equus caballus	92.76	0.00e+00	6152.00
IUUC-Eeu-035118	Erinaceus europaeus	90.13	0.00e+00	2971.00
IUUC-Fca-036213	Felis catus	92.98	0.00e+00	4933.00
IUUC-Fal-037643	Ficedula albicollis	91.06	0.00e+00	6020.00
IUUC-Fox-037971	Fusarium oxysporum	27.03	3.00e-63	238.00
IUUC-Fso-038108	Fusarium solani	27.27	2.00e-61	232.00
IUUC-Ggr-040075	Gaeumannomyces graminis	26.74	6.00e-63	237.00
IUUC-Gga-040511	Gallus gallus	91.12	0.00e+00	6069.00
IUUC-Gac-042024	Gasterosteus aculeatus	89.53	0.00e+00	4305.00
IUUC-Ggo-044924	Gorilla gorilla	89.15	0.00e+00	5911.00
IUUC-Hsa-046913	Homo sapiens	92.32	0.00e+00	6140.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	92.13	0.00e+00	6150.00
IUUC-Lch-049675	Latimeria chalumnae	84.30	0.00e+00	4531.00
IUUC-Loc-052832	Lepisosteus oculatus	86.36	0.00e+00	5641.00
IUUC-Lma-053130	Leptosphaeria maculans	26.78	2.00e-59	225.00
IUUC-Laf-054169	Loxodonta africana	91.72	0.00e+00	6136.00
IUUC-Mcc-055847	Macaca mulatta	91.40	0.00e+00	6024.00
IUUC-Meu-056327	Macropus eugenii	84.42	0.00e+00	1575.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	6.00e-61	231.00
IUUC-Mpo-057310	Magnaporthe poae	26.74	1.00e-61	233.00
IUUC-Mmr-060780	Microcebus murinus	92.47	0.00e+00	6157.00
IUUC-Mmu-063457	Mus musculus	90.58	0.00e+00	6059.00
IUUC-Mpu-066917	Mustela putorius furo	90.52	0.00e+00	5967.00
IUUC-Mlu-067696	Myotis lucifugus	92.49	0.00e+00	6138.00
IUUC-Nfi-068259	Neosartorya fischeri	27.44	1.00e-63	239.00
IUUC-Ncr-068911	Neurospora crassa	26.01	1.00e-59	226.00
IUUC-Nle-069586	Nomascus leucogenys	92.23	0.00e+00	6163.00
IUUC-Opr-070447	Ochotona princeps	89.62	0.00e+00	2782.00
IUUC-Ont-072396	Oreochromis niloticus	81.22	0.00e+00	5223.00
IUUC-Oan-073147	Ornithorhynchus anatinus	93.30	0.00e+00	6203.00
IUUC-Ocu-074324	Oryctolagus cuniculus	92.23	0.00e+00	6120.00
IUUC-Ola-086312	Oryzias latipes	80.36	0.00e+00	5143.00
IUUC-Oga-088878	Otolemur garnettii	92.41	0.00e+00	6153.00
IUUC-Oar-089919	Ovis aries	92.38	0.00e+00	6125.00
IUUC-Ptr-090713	Pan troglodytes	92.50	0.00e+00	5633.00
IUUC-Pan-091957	Papio anubis	95.03	0.00e+00	4974.00
IUUC-Psi-093240	Pelodiscus sinensis	91.79	0.00e+00	6101.00
IUUC-Pma-094469	Petromyzon marinus	73.53	0.00e+00	4095.00
IUUC-Pno-095059	Phaeosphaeria nodorum	32.79	3.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	79.82	0.00e+00	5267.00
IUUC-Pab-098003	Pongo abelii	92.10	0.00e+00	6091.00
IUUC-Pca-100799	Procavia capensis	92.72	0.00e+00	1454.00
IUUC-Pva-103226	Pteropus vampyrus	87.75	0.00e+00	5738.00
IUUC-Pte-104235	Pyrenophora teres	27.02	3.00e-59	225.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.60	4.00e-60	227.00
IUUC-Rno-105389	Rattus norvegicus	92.16	0.00e+00	5363.00
IUUC-Sha-106979	Sarcophilus harrisii	95.56	0.00e+00	6330.00
IUUC-Sar-113444	Sorex araneus	85.65	0.00e+00	5556.00
IUUC-Ssc-115815	Sus scrofa	91.72	0.00e+00	5044.00
IUUC-Tgu-117470	Taeniopygia guttata	92.54	0.00e+00	6075.00
IUUC-Tru-118543	Takifugu rubripes	80.22	0.00e+00	5215.00
IUUC-Tsy-119081	Tarsius syrichta	86.21	0.00e+00	4731.00
IUUC-Tni-120294	Tetraodon nigroviridis	74.75	2.00e-134	472.00
IUUC-Tre-122057	Trichoderma reesei	28.49	5.00e-60	228.00
IUUC-Tvi-122570	Trichoderma virens	35.89	8.00e-59	223.00
IUUC-Tme-127154	Tuber melanosporum	26.67	5.00e-61	229.00
IUUC-Tbe-127801	Tupaia belangeri	88.03	0.00e+00	2868.00
IUUC-Ttr-129262	Tursiops truncatus	88.97	0.00e+00	5803.00
IUUC-Vda-129686	Verticillium dahliae	28.55	3.00e-61	231.00
IUUC-Vpa-130484	Vicugna pacos	92.32	0.00e+00	5134.00
IUUC-Xtr-131769	Xenopus tropicalis	86.00	0.00e+00	5700.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence