iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049297

Ensembl Protein ID

CAY71680

UniProt Accession

C4R7V5; C4R7V5_KOMPG

Genbank Protein ID

CAY71680.1

Protein Name

Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal protein

Genbank Nucleotide ID

FN392322

Gene Name

PAS_chr4_0429

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr4_0429	CAY71680	CAY71680

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.10e-46	154.6	6	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsves 100
           R+ +el++++kdp +g+++++ de+dl +++ +++Gp++tpYegg+Fk++i++p++YPfkPPkv+f +ki+hPn+++  G++Cl+ilk  ++W+p l+++s
   Q: 6    RISRELEDVKKDPLSGVTLEVIDENDLSHLKGTFVGPPGTPYEGGLFKVDIQIPSNYPFKPPKVQFDSKIYHPNISSVtGAICLDILK--NAWTPILTLKS 104
           899**************************************************************************99********9..*********** PP
   S: 101  vllsiqsllaepnpesplneeaaellkknreeykkkvr 138
            l+s+qsll++p+p++p+++++a+ + k+++e++++++
   Q: 105  TLISLQSLLQSPEPSDPQDAQVASVFLKDKREFDRTAK 142
           **********************************9987 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MTSIKRISRE LEDVKKDPLS GVTLEVIDEN DLSHLKGTFV GPPGTPYEGG LFKVDIQIPS 60
NYPFKPPKVQ FDSKIYHPNI SSVTGAICLD ILKNAWTPIL TLKSTLISLQ SLLQSPEPSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTAGCA TTAAACGAAT CAGCAGAGAA TTGGAGGACG TCAAGAAGGA TCCATTGAGT 60
GGGGTAACCT TAGAGGTCAT CGACGAGAAT GATCTGTCAC ACCTAAAAGG TACCTTCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR009060--UBA-like
IPR015368--UBA_C_fun
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF09288--UBA_3
PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000502--C:proteasome complex
GO:0005524--F:ATP binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0016050--P:vesicle organization

KEGG

ppa:PAS_chr4_0429

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	50.00	1.00e-27	114.00
IUUC-Aml-001286	Ailuropoda melanoleuca	49.02	2.00e-37	146.00
IUUC-Atr-003063	Amborella trichopoda	53.33	7.00e-34	134.00
IUUC-Apl-004122	Anas platyrhynchos	52.67	3.00e-35	139.00
IUUC-Aly-006390	Arabidopsis lyrata	45.36	1.00e-44	170.00
IUUC-Ath-006637	Arabidopsis thaliana	42.78	2.00e-41	159.00
IUUC-Ago-007714	Ashbya gossypii	49.16	6.00e-66	241.00
IUUC-Acl-008189	Aspergillus clavatus	41.37	2.00e-38	150.00
IUUC-Afl-008489	Aspergillus flavus	45.45	6.00e-43	165.00
IUUC-Afu-008850	Aspergillus fumigatus	44.14	8.00e-44	168.00
IUUC-Ani-009361	Aspergillus nidulans	44.04	6.00e-39	151.00
IUUC-Ang-009548	Aspergillus niger	42.31	2.00e-37	146.00
IUUC-Aor-010105	Aspergillus oryzae	45.45	6.00e-43	165.00
IUUC-Ate-010389	Aspergillus terreus	41.91	2.00e-39	153.00
IUUC-Ame-011454	Astyanax mexicanus	49.67	1.00e-37	147.00
IUUC-Bgr-012255	Blumeria graminis	39.57	2.00e-44	170.00
IUUC-Bta-012992	Bos taurus	49.02	2.00e-37	146.00
IUUC-Bci-013806	Botrytis cinerea	40.00	8.00e-46	174.00
IUUC-Bdi-015024	Brachypodium distachyon	52.98	8.00e-36	140.00
IUUC-Bol-015985	Brassica oleracea	46.99	7.00e-46	174.00
IUUC-Bra-016805	Brassica rapa	46.99	4.00e-46	175.00
IUUC-Cel-018353	Caenorhabditis elegans	48.00	5.00e-41	158.00
IUUC-Cja-019051	Callithrix jacchus	49.02	4.00e-37	145.00
IUUC-Cfa-020016	Canis familiaris	49.02	2.00e-37	146.00
IUUC-Cpo-022026	Cavia porcellus	49.02	2.00e-37	146.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	52.32	4.00e-32	128.00
IUUC-Csa-023059	Chlorocebus sabaeus	49.02	2.00e-37	146.00
IUUC-Cin-025598	Ciona intestinalis	54.19	1.00e-37	146.00
IUUC-Csv-025831	Ciona savignyi	56.13	6.00e-38	147.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	52.35	8.00e-44	167.00
IUUC-Cne-027068	Cryptococcus neoformans	46.81	5.00e-58	214.00
IUUC-Dre-028139	Danio rerio	49.02	2.00e-37	146.00
IUUC-Dse-031335	Dothistroma septosporum	46.72	7.00e-52	194.00
IUUC-Eca-033428	Equus caballus	49.02	2.00e-37	146.00
IUUC-Fca-035366	Felis catus	49.02	2.00e-37	146.00
IUUC-Fal-037016	Ficedula albicollis	49.02	2.00e-37	146.00
IUUC-Fox-037969	Fusarium oxysporum	40.34	1.00e-48	183.00
IUUC-Fso-038296	Fusarium solani	40.08	8.00e-47	177.00
IUUC-Gmo-039135	Gadus morhua	49.67	3.00e-37	145.00
IUUC-Ggr-039768	Gaeumannomyces graminis	40.00	2.00e-39	153.00
IUUC-Gga-041018	Gallus gallus	49.02	2.00e-37	146.00
IUUC-Gac-041503	Gasterosteus aculeatus	49.67	1.00e-37	147.00
IUUC-Gma-042779	Glycine max	53.33	4.00e-44	168.00
IUUC-Ggo-045032	Gorilla gorilla	49.02	2.00e-37	146.00
IUUC-Hsa-046490	Homo sapiens	49.02	2.00e-37	146.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	49.02	2.00e-37	146.00
IUUC-Lch-050588	Latimeria chalumnae	54.96	4.00e-40	155.00
IUUC-Lpe-051070	Leersia perrieri	52.98	7.00e-31	124.00
IUUC-Loc-052549	Lepisosteus oculatus	49.02	2.00e-37	145.00
IUUC-Lma-052949	Leptosphaeria maculans	40.42	5.00e-52	195.00
IUUC-Mcc-055606	Macaca mulatta	49.02	2.00e-37	146.00
IUUC-Mor-056946	Magnaporthe oryzae	38.14	3.00e-38	149.00
IUUC-Mpo-057441	Magnaporthe poae	40.00	1.00e-39	154.00
IUUC-Mtr-058002	Medicago truncatula	50.34	4.00e-44	168.00
IUUC-Mla-059007	Melampsora laricipopulina	48.83	2.00e-54	203.00
IUUC-Mga-059254	Meleagris gallopavo	52.67	3.00e-35	139.00
IUUC-Mvi-060346	Microbotryum violaceum	41.95	2.00e-52	196.00
IUUC-Mmr-061211	Microcebus murinus	49.02	2.00e-37	146.00
IUUC-Mdo-062458	Monodelphis domestica	48.37	2.00e-35	139.00
IUUC-Mmu-063648	Mus musculus	49.02	2.00e-37	146.00
IUUC-Mac-065447	Musa acuminata	54.30	2.00e-39	152.00
IUUC-Mpu-066407	Mustela putorius furo	49.02	3.00e-37	146.00
IUUC-Mlu-067682	Myotis lucifugus	48.68	6.00e-36	141.00
IUUC-Nfi-068517	Neosartorya fischeri	44.14	6.00e-44	168.00
IUUC-Ncr-068749	Neurospora crassa	42.32	3.00e-52	196.00
IUUC-Opr-070651	Ochotona princeps	49.02	2.00e-37	146.00
IUUC-Ont-071595	Oreochromis niloticus	49.67	1.00e-37	147.00
IUUC-Ocu-074939	Oryctolagus cuniculus	49.02	2.00e-37	146.00
IUUC-Oba-075530	Oryza barthii	53.33	2.00e-32	129.00
IUUC-Obr-076838	Oryza brachyantha	52.67	8.00e-32	127.00
IUUC-Ogl-077606	Oryza glaberrima	53.33	2.00e-32	129.00
IUUC-Ogu-078238	Oryza glumaepatula	53.33	2.00e-32	129.00
IUUC-Oin-079643	Oryza indica	53.29	7.00e-33	131.00
IUUC-Ome-081274	Oryza meridionalis	53.33	2.00e-32	129.00
IUUC-Oni-082651	Oryza nivara	53.33	2.00e-32	129.00
IUUC-Opu-083933	Oryza punctata	53.33	3.00e-32	129.00
IUUC-Oru-085054	Oryza rufipogon	53.29	7.00e-33	131.00
IUUC-Osa-085716	Oryza sativa	53.29	7.00e-33	131.00
IUUC-Ola-087278	Oryzias latipes	49.06	6.00e-38	147.00
IUUC-Olu-087846	Ostreococcus lucimarinus	54.00	5.00e-46	174.00
IUUC-Ptr-091295	Pan troglodytes	49.02	2.00e-37	146.00
IUUC-Psi-093498	Pelodiscus sinensis	49.02	2.00e-37	146.00
IUUC-Pma-094115	Petromyzon marinus	49.04	3.00e-38	149.00
IUUC-Pno-095102	Phaeosphaeria nodorum	39.91	5.00e-53	198.00
IUUC-Ppa-095326	Physcomitrella patens	58.00	1.00e-40	156.00
IUUC-Pfo-096174	Poecilia formosa	50.33	7.00e-38	147.00
IUUC-Pab-098279	Pongo abelii	49.02	2.00e-37	146.00
IUUC-Pop-099543	Populus trichocarpa	50.00	3.00e-43	166.00
IUUC-Pca-100782	Procavia capensis	49.02	5.00e-36	141.00
IUUC-Ppe-101789	Prunus persica	44.92	7.00e-38	148.00
IUUC-Pgr-103643	Puccinia graminis	55.48	4.00e-48	182.00
IUUC-Ptt-103772	Puccinia triticina	56.55	2.00e-47	180.00
IUUC-Pte-104370	Pyrenophora teres	38.63	3.00e-49	185.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	38.63	7.00e-49	184.00
IUUC-Rno-104984	Rattus norvegicus	49.02	2.00e-37	146.00
IUUC-Sce-106394	Saccharomyces cerevisiae	52.52	1.00e-62	230.00
IUUC-Sha-106624	Sarcophilus harrisii	47.71	3.00e-37	145.00
IUUC-Sja-107866	Schizosaccharomyces japonicus	47.66	2.00e-53	199.00
IUUC-Spo-108209	Schizosaccharomyces pombe	48.86	6.00e-56	207.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	41.15	2.00e-44	169.00
IUUC-Smo-109233	Selaginella moellendorffii	56.00	6.00e-40	154.00
IUUC-Sit-110639	Setaria italica	52.67	2.00e-35	139.00
IUUC-Sly-110978	Solanum lycopersicum	50.67	8.00e-44	167.00
IUUC-Stu-112088	Solanum tuberosum	51.33	2.00e-44	169.00
IUUC-Sbi-113986	Sorghum bicolor	52.67	3.00e-35	139.00
IUUC-Sre-115046	Sporisorium reilianum	45.11	1.00e-54	203.00
IUUC-Ssc-116314	Sus scrofa	49.02	2.00e-37	146.00
IUUC-Tru-118196	Takifugu rubripes	50.33	2.00e-38	149.00
IUUC-Tsy-119208	Tarsius syrichta	48.37	1.00e-36	144.00
IUUC-Tni-119667	Tetraodon nigroviridis	49.02	2.00e-37	146.00
IUUC-Tca-121446	Theobroma cacao	49.33	3.00e-41	159.00
IUUC-Tre-122053	Trichoderma reesei	38.39	2.00e-42	163.00
IUUC-Tvi-122533	Trichoderma virens	37.10	2.00e-42	163.00
IUUC-Tae-125271	Triticum aestivum	51.66	2.00e-30	123.00
IUUC-Tme-127024	Tuber melanosporum	42.69	2.00e-54	203.00
IUUC-Tbe-127752	Tupaia belangeri	48.37	1.00e-36	143.00
IUUC-Uma-129512	Ustilago maydis	44.26	5.00e-54	201.00
IUUC-Vda-129947	Verticillium dahliae	42.60	1.00e-44	171.00
IUUC-Vpa-130481	Vicugna pacos	49.02	3.00e-37	145.00
IUUC-Vvi-131429	Vitis vinifera	50.67	7.00e-44	167.00
IUUC-Xma-134165	Xiphophorus maculatus	50.33	6.00e-38	148.00
IUUC-Yli-134523	Yarrowia lipolytica	51.05	1.00e-60	223.00
IUUC-Zma-135733	Zea mays	48.77	1.00e-32	130.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence