iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091654

Ensembl Protein ID

ENSPTRP00000016628.3

UniProt Accession

H2QE29; H2QE29_PANTR

Genbank Protein ID

ENSPTRP00000016628

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03111753

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000009768.3	ENSPTRT00000017946.3	ENSPTRP00000016628.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	87.29	0.00e+00	1066.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	42.23	1.00e-57	222.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	93.95	0.00e+00	1170.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	93.95	0.00e+00	1170.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	88.16	0.00e+00	1098.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	87.96	0.00e+00	1088.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	27.23	2.00e-20	96.30	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	31.48	2.00e-28	122.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVNSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKDLLKHVF PEFKESDAMF AAERAPDWVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGCGTCCCC ACCCGACGGC 60
TCGGCCTTGG TCAGCCCGCA GCCTCCGCCC GGCGCTGAGT CAGCGCGGCC CCGAGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	82.80	0.00e+00	905.00
IUUC-Apl-003662	Anas platyrhynchos	76.61	0.00e+00	860.00
IUUC-Aca-004940	Anolis carolinensis	77.44	0.00e+00	1026.00
IUUC-Ago-007931	Ashbya gossypii	28.50	4.00e-20	92.80
IUUC-Acl-008274	Aspergillus clavatus	26.71	6.00e-28	119.00
IUUC-Afl-008521	Aspergillus flavus	27.73	5.00e-28	119.00
IUUC-Afu-008774	Aspergillus fumigatus	28.62	2.00e-28	120.00
IUUC-Ani-009445	Aspergillus nidulans	27.78	2.00e-29	124.00
IUUC-Ang-009863	Aspergillus niger	28.88	1.00e-30	128.00
IUUC-Ate-010444	Aspergillus terreus	30.04	2.00e-30	127.00
IUUC-Ame-011111	Astyanax mexicanus	72.78	0.00e+00	853.00
IUUC-Bgr-012087	Blumeria graminis	27.50	5.00e-29	122.00
IUUC-Bta-012506	Bos taurus	86.91	0.00e+00	1070.00
IUUC-Bci-013782	Botrytis cinerea	28.25	9.00e-28	118.00
IUUC-Cel-018493	Caenorhabditis elegans	44.55	1.00e-50	194.00
IUUC-Cja-019998	Callithrix jacchus	92.78	0.00e+00	1116.00
IUUC-Cfa-020615	Canis familiaris	84.29	0.00e+00	983.00
IUUC-Cpo-022019	Cavia porcellus	87.55	0.00e+00	1140.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	42.65	9.00e-11	62.00
IUUC-Csa-023596	Chlorocebus sabaeus	93.44	0.00e+00	1054.00
IUUC-Cin-025488	Ciona intestinalis	43.24	1.00e-110	394.00
IUUC-Csv-025802	Ciona savignyi	46.42	2.00e-97	349.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	30.21	3.00e-28	120.00
IUUC-Cne-026847	Cryptococcus neoformans	29.90	1.00e-30	128.00
IUUC-Dre-028353	Danio rerio	72.13	0.00e+00	826.00
IUUC-Dno-029005	Dasypus novemcinctus	81.34	0.00e+00	1035.00
IUUC-Dor-030280	Dipodomys ordii	86.06	0.00e+00	1068.00
IUUC-Dse-031238	Dothistroma septosporum	32.26	8.00e-30	125.00
IUUC-Dme-031952	Drosophila melanogaster	42.65	2.00e-60	227.00
IUUC-Ete-032235	Echinops telfairi	77.73	2.00e-100	359.00
IUUC-Eca-033873	Equus caballus	88.28	0.00e+00	1071.00
IUUC-Eeu-034652	Erinaceus europaeus	73.74	3.00e-73	269.00
IUUC-Fca-036563	Felis catus	85.51	0.00e+00	1025.00
IUUC-Fal-036649	Ficedula albicollis	77.87	0.00e+00	927.00
IUUC-Fox-037962	Fusarium oxysporum	28.27	1.00e-27	118.00
IUUC-Fso-038396	Fusarium solani	28.98	4.00e-28	119.00
IUUC-Gmo-039510	Gadus morhua	69.59	0.00e+00	852.00
IUUC-Ggr-039938	Gaeumannomyces graminis	28.72	1.00e-26	114.00
IUUC-Gga-040201	Gallus gallus	77.46	0.00e+00	996.00
IUUC-Gac-041459	Gasterosteus aculeatus	69.86	0.00e+00	854.00
IUUC-Ggo-044573	Gorilla gorilla	94.08	0.00e+00	1169.00
IUUC-Hsa-046009	Homo sapiens	93.95	0.00e+00	1211.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	89.19	0.00e+00	1139.00
IUUC-Kpa-049327	Komagataella pastoris	26.78	2.00e-24	107.00
IUUC-Lch-049944	Latimeria chalumnae	73.11	2.00e-156	545.00
IUUC-Loc-051850	Lepisosteus oculatus	73.51	0.00e+00	917.00
IUUC-Lma-053252	Leptosphaeria maculans	30.43	3.00e-29	124.00
IUUC-Laf-053346	Loxodonta africana	78.72	0.00e+00	934.00
IUUC-Mcc-055789	Macaca mulatta	93.37	0.00e+00	1122.00
IUUC-Meu-056329	Macropus eugenii	72.69	2.00e-159	556.00
IUUC-Mor-057205	Magnaporthe oryzae	29.11	5.00e-27	116.00
IUUC-Mpo-057295	Magnaporthe poae	27.65	2.00e-27	117.00
IUUC-Mla-058849	Melampsora laricipopulina	30.45	3.00e-26	113.00
IUUC-Mga-059361	Meleagris gallopavo	75.84	0.00e+00	926.00
IUUC-Mvi-060561	Microbotryum violaceum	29.93	1.00e-29	124.00
IUUC-Mmr-061122	Microcebus murinus	89.00	0.00e+00	937.00
IUUC-Mdo-062171	Monodelphis domestica	83.65	0.00e+00	1081.00
IUUC-Mmu-063952	Mus musculus	88.16	0.00e+00	1174.00
IUUC-Mpu-065852	Mustela putorius furo	85.92	0.00e+00	996.00
IUUC-Mlu-066996	Myotis lucifugus	84.60	5.00e-149	520.00
IUUC-Nfi-068539	Neosartorya fischeri	28.62	9.00e-29	122.00
IUUC-Ncr-068726	Neurospora crassa	34.23	3.00e-28	120.00
IUUC-Nle-070148	Nomascus leucogenys	87.64	0.00e+00	1031.00
IUUC-Opr-070833	Ochotona princeps	70.39	0.00e+00	713.00
IUUC-Ont-071261	Oreochromis niloticus	71.39	0.00e+00	865.00
IUUC-Oan-073684	Ornithorhynchus anatinus	61.76	1.00e-122	432.00
IUUC-Ola-087570	Oryzias latipes	68.47	0.00e+00	872.00
IUUC-Oga-089087	Otolemur garnettii	83.40	0.00e+00	987.00
IUUC-Oar-089534	Ovis aries	86.50	0.00e+00	1066.00
IUUC-Pan-092652	Papio anubis	93.69	0.00e+00	1128.00
IUUC-Pno-095125	Phaeosphaeria nodorum	31.74	1.00e-30	127.00
IUUC-Pfo-096757	Poecilia formosa	70.72	0.00e+00	835.00
IUUC-Pab-097788	Pongo abelii	91.01	0.00e+00	776.00
IUUC-Pca-100145	Procavia capensis	83.67	0.00e+00	934.00
IUUC-Pva-102965	Pteropus vampyrus	81.00	0.00e+00	1004.00
IUUC-Pgr-103609	Puccinia graminis	31.63	2.00e-27	117.00
IUUC-Ptt-103865	Puccinia triticina	33.16	4.00e-28	120.00
IUUC-Pte-104095	Pyrenophora teres	29.96	1.00e-29	124.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	30.49	4.00e-29	123.00
IUUC-Rno-105125	Rattus norvegicus	87.85	0.00e+00	1097.00
IUUC-Sce-106192	Saccharomyces cerevisiae	27.03	2.00e-21	97.40
IUUC-Sha-107066	Sarcophilus harrisii	84.15	0.00e+00	1046.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	29.32	1.00e-29	124.00
IUUC-Spo-108220	Schizosaccharomyces pombe	31.48	3.00e-29	123.00
IUUC-Smo-109256	Selaginella moellendorffii	43.53	1.00e-18	84.00
IUUC-Stu-112464	Solanum tuberosum	45.90	3.00e-13	70.90
IUUC-Sar-113393	Sorex araneus	70.53	4.00e-75	275.00
IUUC-Sre-114986	Sporisorium reilianum	31.84	1.00e-31	131.00
IUUC-Tgu-117505	Taeniopygia guttata	77.22	0.00e+00	942.00
IUUC-Tru-118494	Takifugu rubripes	72.13	0.00e+00	892.00
IUUC-Tsy-119626	Tarsius syrichta	100.00	2.00e-54	207.00
IUUC-Tni-120174	Tetraodon nigroviridis	68.42	0.00e+00	898.00
IUUC-Tre-122191	Trichoderma reesei	29.45	8.00e-29	122.00
IUUC-Tvi-122318	Trichoderma virens	29.12	1.00e-29	124.00
IUUC-Tme-126914	Tuber melanosporum	28.72	5.00e-31	129.00
IUUC-Ttr-129095	Tursiops truncatus	87.18	0.00e+00	1114.00
IUUC-Uma-129475	Ustilago maydis	29.91	7.00e-29	122.00
IUUC-Vda-129908	Verticillium dahliae	29.39	1.00e-23	104.00
IUUC-Xtr-131900	Xenopus tropicalis	70.96	0.00e+00	920.00
IUUC-Xma-133124	Xiphophorus maculatus	70.68	0.00e+00	875.00
IUUC-Yli-134682	Yarrowia lipolytica	28.70	1.00e-25	111.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence