iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007766

Ensembl Protein ID

AAS54658

UniProt Accession

Q74ZN0; HIR1_ASHGO

Genbank Protein ID

AAS54658.2

Protein Name

Protein HIR1

Genbank Nucleotide ID

AE016820

Gene Name

HIR1; AGR168W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AGR168W	AAS54658	AAS54658

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-25	85.4	76	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht+svt+l+f +d ++l+sGsdD+ + +W+ 
   Q: 76   HTGSVTALKFsPDnKYLASGSDDKILLIWEK 106
           9**********998***************95 PP

Organism

Ashbya gossypii

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKILKLPWLT HQEGQRNYEI YTVDVSSDGQ RVATGGLDGK IRIWSVADIL VFAKPKVSWP 60
AREEQLRKPL ANMSRHTGSV TALKFSPDNK YLASGSDDKI LLIWEKEEGA VQPLFDMEND 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGATCC TTAAGTTGCC CTGGCTTACT CACCAGGAGG GGCAGAGGAA TTATGAGATA 60
TATACGGTGG ACGTGAGCTC CGACGGACAA CGAGTAGCGA CCGGAGGGCT AGATGGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR006141--Intein_N
IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0000417--C:HIR complex
GO:0000790--C:nuclear chromatin
GO:0003677--F:DNA binding
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0016539--P:intein-mediated protein splicing
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0031935--P:regulation of chromatin silencing
GO:0006368--P:transcription elongation from RNA polymerase II promoter

KEGG

ago:AGOS_AGR168W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	30.15	1.00e-55	209.00
IUUC-Aml-001723	Ailuropoda melanoleuca	30.32	2.00e-52	199.00
IUUC-Atr-003132	Amborella trichopoda	31.38	3.00e-58	218.00
IUUC-Apl-003197	Anas platyrhynchos	30.32	2.00e-53	202.00
IUUC-Aca-004733	Anolis carolinensis	28.05	9.00e-55	206.00
IUUC-Aly-005446	Arabidopsis lyrata	30.08	3.00e-55	207.00
IUUC-Ath-007627	Arabidopsis thaliana	30.53	1.00e-59	222.00
IUUC-Acl-008104	Aspergillus clavatus	38.46	2.00e-116	411.00
IUUC-Afl-008591	Aspergillus flavus	32.40	3.00e-124	437.00
IUUC-Afu-008781	Aspergillus fumigatus	31.79	4.00e-110	390.00
IUUC-Ani-009272	Aspergillus nidulans	31.62	5.00e-109	386.00
IUUC-Ang-009655	Aspergillus niger	32.56	1.00e-120	425.00
IUUC-Aor-010119	Aspergillus oryzae	32.40	3.00e-124	437.00
IUUC-Ate-010530	Aspergillus terreus	30.35	1.00e-106	379.00
IUUC-Bgr-012237	Blumeria graminis	47.30	4.00e-117	413.00
IUUC-Bta-013320	Bos taurus	30.32	3.00e-52	197.00
IUUC-Bci-013795	Botrytis cinerea	31.79	1.00e-118	419.00
IUUC-Bdi-014075	Brachypodium distachyon	32.49	9.00e-61	226.00
IUUC-Bol-016440	Brassica oleracea	33.57	2.00e-59	222.00
IUUC-Bra-016651	Brassica rapa	33.80	5.00e-60	224.00
IUUC-Cel-018692	Caenorhabditis elegans	26.01	7.00e-31	127.00
IUUC-Cja-018987	Callithrix jacchus	29.95	5.00e-47	180.00
IUUC-Cfa-020132	Canis familiaris	30.32	1.00e-52	199.00
IUUC-Cpo-021484	Cavia porcellus	30.37	8.00e-55	206.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	31.84	1.00e-54	206.00
IUUC-Csa-023081	Chlorocebus sabaeus	30.37	8.00e-55	206.00
IUUC-Cin-025182	Ciona intestinalis	30.84	5.00e-54	204.00
IUUC-Csv-026154	Ciona savignyi	30.23	2.00e-52	198.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	31.51	2.00e-121	428.00
IUUC-Cne-026891	Cryptococcus neoformans	37.31	2.00e-77	281.00
IUUC-Cme-027349	Cyanidioschyzon merolae	23.72	3.00e-31	128.00
IUUC-Dre-027655	Danio rerio	29.23	9.00e-55	206.00
IUUC-Dno-029557	Dasypus novemcinctus	28.54	1.00e-45	176.00
IUUC-Dor-030687	Dipodomys ordii	26.21	7.00e-43	167.00
IUUC-Dse-031334	Dothistroma septosporum	32.35	4.00e-118	417.00
IUUC-Dme-031746	Drosophila melanogaster	32.29	4.00e-57	214.00
IUUC-Ete-032384	Echinops telfairi	25.92	6.00e-35	140.00
IUUC-Eca-033430	Equus caballus	30.07	5.00e-52	197.00
IUUC-Fca-036121	Felis catus	30.32	1.00e-52	199.00
IUUC-Fal-036817	Ficedula albicollis	30.32	2.00e-53	202.00
IUUC-Fox-037906	Fusarium oxysporum	37.19	2.00e-124	437.00
IUUC-Fso-038409	Fusarium solani	32.88	7.00e-126	442.00
IUUC-Gmo-039151	Gadus morhua	31.46	2.00e-57	215.00
IUUC-Ggr-040016	Gaeumannomyces graminis	44.40	8.00e-115	406.00
IUUC-Gga-040936	Gallus gallus	30.37	1.00e-55	209.00
IUUC-Gac-041405	Gasterosteus aculeatus	27.68	6.00e-52	197.00
IUUC-Gma-042800	Glycine max	33.10	2.00e-60	225.00
IUUC-Ggo-045430	Gorilla gorilla	30.37	2.00e-54	205.00
IUUC-Hsa-046442	Homo sapiens	30.37	2.00e-54	205.00
IUUC-Hvu-047587	Hordeum vulgare	33.15	1.00e-52	199.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	33.70	2.00e-41	160.00
IUUC-Kpa-049145	Komagataella pastoris	52.38	7.00e-149	519.00
IUUC-Lch-050474	Latimeria chalumnae	30.71	7.00e-56	210.00
IUUC-Lpe-051209	Leersia perrieri	29.41	1.00e-51	196.00
IUUC-Loc-052119	Lepisosteus oculatus	30.48	1.00e-53	202.00
IUUC-Lma-053237	Leptosphaeria maculans	33.22	4.00e-120	423.00
IUUC-Laf-053718	Loxodonta africana	30.14	1.00e-54	206.00
IUUC-Mcc-055621	Macaca mulatta	29.95	2.00e-47	181.00
IUUC-Meu-055914	Macropus eugenii	30.77	5.00e-36	144.00
IUUC-Mor-057090	Magnaporthe oryzae	44.72	1.00e-111	395.00
IUUC-Mpo-057364	Magnaporthe poae	44.40	1.00e-114	405.00
IUUC-Mtr-058691	Medicago truncatula	29.71	4.00e-61	228.00
IUUC-Mla-058914	Melampsora laricipopulina	27.64	3.00e-75	274.00
IUUC-Mga-060181	Meleagris gallopavo	30.32	2.00e-53	202.00
IUUC-Mvi-060432	Microbotryum violaceum	34.74	1.00e-64	239.00
IUUC-Mmr-060871	Microcebus murinus	30.37	2.00e-54	205.00
IUUC-Mdo-062301	Monodelphis domestica	30.61	5.00e-55	207.00
IUUC-Mmu-063888	Mus musculus	30.37	9.00e-55	206.00
IUUC-Mac-065137	Musa acuminata	31.70	2.00e-56	211.00
IUUC-Mpu-066732	Mustela putorius furo	30.32	2.00e-52	198.00
IUUC-Mlu-067542	Myotis lucifugus	30.32	2.00e-52	198.00
IUUC-Nfi-068396	Neosartorya fischeri	31.58	3.00e-111	394.00
IUUC-Ncr-068842	Neurospora crassa	33.84	1.00e-123	435.00
IUUC-Nle-070156	Nomascus leucogenys	30.37	2.00e-54	205.00
IUUC-Opr-070808	Ochotona princeps	29.58	2.00e-35	142.00
IUUC-Ont-072105	Oreochromis niloticus	29.86	7.00e-53	200.00
IUUC-Ocu-074962	Oryctolagus cuniculus	30.32	1.00e-52	199.00
IUUC-Oba-075178	Oryza barthii	32.71	3.00e-58	218.00
IUUC-Obr-076399	Oryza brachyantha	33.26	5.00e-61	227.00
IUUC-Ogu-078797	Oryza glumaepatula	32.71	3.00e-58	218.00
IUUC-Oin-080085	Oryza indica	32.25	3.00e-50	191.00
IUUC-Olo-081048	Oryza longistaminata	32.24	2.00e-43	169.00
IUUC-Ome-081324	Oryza meridionalis	32.71	2.00e-58	218.00
IUUC-Oni-082548	Oryza nivara	32.71	2.00e-58	218.00
IUUC-Opu-084008	Oryza punctata	32.79	4.00e-60	224.00
IUUC-Oru-084339	Oryza rufipogon	32.71	3.00e-58	218.00
IUUC-Osa-085782	Oryza sativa	32.71	3.00e-58	218.00
IUUC-Ola-087302	Oryzias latipes	30.40	2.00e-48	185.00
IUUC-Olu-087611	Ostreococcus lucimarinus	32.72	1.00e-60	225.00
IUUC-Oga-087935	Otolemur garnettii	28.02	2.00e-52	199.00
IUUC-Oar-089229	Ovis aries	26.63	6.00e-42	164.00
IUUC-Ptr-090715	Pan troglodytes	30.37	2.00e-54	205.00
IUUC-Pan-092318	Papio anubis	30.32	1.00e-52	199.00
IUUC-Psi-094053	Pelodiscus sinensis	29.60	4.00e-53	201.00
IUUC-Pno-094985	Phaeosphaeria nodorum	44.77	4.00e-103	367.00
IUUC-Ppa-095819	Physcomitrella patens	32.57	1.00e-58	219.00
IUUC-Pfo-096857	Poecilia formosa	30.55	6.00e-52	197.00
IUUC-Pab-098047	Pongo abelii	30.37	2.00e-54	205.00
IUUC-Pop-099865	Populus trichocarpa	33.01	3.00e-60	224.00
IUUC-Pca-100558	Procavia capensis	32.86	3.00e-29	121.00
IUUC-Ppe-101261	Prunus persica	31.35	3.00e-63	234.00
IUUC-Pva-102683	Pteropus vampyrus	30.37	3.00e-53	201.00
IUUC-Pgr-103660	Puccinia graminis	35.18	2.00e-70	258.00
IUUC-Ptt-103900	Puccinia triticina	30.55	1.00e-70	259.00
IUUC-Pte-104209	Pyrenophora teres	32.30	1.00e-118	419.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	32.00	1.00e-116	412.00
IUUC-Rno-105566	Rattus norvegicus	30.37	1.00e-54	206.00
IUUC-Sce-106291	Saccharomyces cerevisiae	54.04	0.00e+00	885.00
IUUC-Sha-107514	Sarcophilus harrisii	28.54	1.00e-42	166.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	34.61	3.00e-125	440.00
IUUC-Spo-108162	Schizosaccharomyces pombe	34.00	1.00e-123	435.00
IUUC-Ssl-108629	Sclerotinia sclerotiorum	50.00	1.00e-33	136.00
IUUC-Smo-109533	Selaginella moellendorffii	31.28	2.00e-59	221.00
IUUC-Sit-109980	Setaria italica	30.56	2.00e-63	235.00
IUUC-Sly-111547	Solanum lycopersicum	25.85	1.00e-59	223.00
IUUC-Stu-112705	Solanum tuberosum	30.35	3.00e-58	218.00
IUUC-Sar-113222	Sorex araneus	28.75	5.00e-45	174.00
IUUC-Sbi-114528	Sorghum bicolor	32.24	8.00e-65	239.00
IUUC-Sre-115061	Sporisorium reilianum	33.72	3.00e-78	285.00
IUUC-Ssc-116364	Sus scrofa	30.32	2.00e-52	199.00
IUUC-Tgu-116645	Taeniopygia guttata	30.32	2.00e-53	202.00
IUUC-Tru-117590	Takifugu rubripes	31.50	3.00e-54	204.00
IUUC-Tsy-119212	Tarsius syrichta	31.07	3.00e-44	171.00
IUUC-Tni-119915	Tetraodon nigroviridis	31.13	1.00e-54	206.00
IUUC-Tca-121765	Theobroma cacao	30.53	7.00e-61	226.00
IUUC-Tre-121887	Trichoderma reesei	31.69	9.00e-117	412.00
IUUC-Tvi-122262	Trichoderma virens	32.35	3.00e-117	414.00
IUUC-Tur-126483	Triticum urartu	32.03	6.00e-60	223.00
IUUC-Tme-127202	Tuber melanosporum	33.17	9.00e-110	389.00
IUUC-Tbe-127350	Tupaia belangeri	26.25	2.00e-27	115.00
IUUC-Uma-129465	Ustilago maydis	31.80	7.00e-77	280.00
IUUC-Vda-129844	Verticillium dahliae	37.80	2.00e-115	408.00
IUUC-Vvi-131397	Vitis vinifera	33.80	6.00e-62	230.00
IUUC-Xtr-132057	Xenopus tropicalis	29.33	4.00e-55	207.00
IUUC-Xma-134139	Xiphophorus maculatus	29.94	4.00e-45	173.00
IUUC-Yli-134424	Yarrowia lipolytica	51.74	3.00e-126	444.00
IUUC-Zma-135839	Zea mays	31.10	2.00e-62	232.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence