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Tag Content
iUUCD ID IUUC-Fca-035367
Ensembl Protein ID ENSFCAP00000009076.3
UniProt Accession M3WC46; M3WC46_FELCA
Genbank Protein ID ENSFCAP00000009076
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AANG02047428
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000009785.3 ENSFCAT00000009788.3 ENSFCAP00000009076.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 8.30e-22 76.1 951 979
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
    ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 951 AFSQVDPEVFAALPAELQKELKAAYDQRQ 979
    59*************************98 PP
   

Organism Felis catus
Functional Description
(View)

Functional Description



     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
FTDPSAEELR KLMMLHGGQY HVYYSRSKTT HIIATNLPNA KIKELKGEKV IRPEWIVESI 60
KAGRLLSYIP YQLYSKQSNM QKGLNFNPVC KPEDPVPGPS SVSKQLNNRV NHIIKKIETE 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Fca-035367|UBD,UBM|Felis catus
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Nucleotide Sequence
(Fasta)
TTTACAGATC CTTCTGCTGA GGAATTGCGA AAGCTAATGA TGTTGCATGG AGGTCAATAC 60
CATGTGTATT ATTCCAGATC CAAAACAACA CACATTATTG CCACAAATCT TCCAAATGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Fca-035367|UBD,UBM|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 31.14 6.00e-33 136.00
IUUC-Aml-001185 Ailuropoda melanoleuca 92.06 0.00e+00 2132.00
IUUC-Atr-002915 Amborella trichopoda 32.52 6.00e-85 309.00
IUUC-Apl-004054 Anas platyrhynchos 77.22 0.00e+00 1775.00
IUUC-Aca-004304 Anolis carolinensis 69.03 0.00e+00 1564.00
IUUC-Aly-005696 Arabidopsis lyrata 33.97 1.00e-85 311.00
IUUC-Ath-006893 Arabidopsis thaliana 35.61 5.00e-85 309.00
IUUC-Ago-007722 Ashbya gossypii 28.57 2.00e-37 150.00
IUUC-Acl-008347 Aspergillus clavatus 37.10 1.00e-87 318.00
IUUC-Afl-008444 Aspergillus flavus 36.07 2.00e-86 314.00
IUUC-Afu-008837 Aspergillus fumigatus 31.39 7.00e-84 305.00
IUUC-Ani-009188 Aspergillus nidulans 38.31 8.00e-92 332.00
IUUC-Ang-009866 Aspergillus niger 33.43 6.00e-98 352.00
IUUC-Aor-010107 Aspergillus oryzae 36.07 2.00e-86 314.00
IUUC-Ate-010359 Aspergillus terreus 32.58 9.00e-91 328.00
IUUC-Ame-010664 Astyanax mexicanus 54.03 0.00e+00 914.00
IUUC-Bgr-012244 Blumeria graminis 29.27 2.00e-83 304.00
IUUC-Bta-013405 Bos taurus 82.14 0.00e+00 1837.00
IUUC-Bci-013849 Botrytis cinerea 31.04 9.00e-88 318.00
IUUC-Bdi-014066 Brachypodium distachyon 36.73 1.00e-85 311.00
IUUC-Bol-015544 Brassica oleracea 37.01 1.00e-87 317.00
IUUC-Bra-017792 Brassica rapa 34.41 5.00e-83 303.00
IUUC-Cel-018148 Caenorhabditis elegans 35.74 2.00e-81 297.00
IUUC-Cja-019742 Callithrix jacchus 76.11 0.00e+00 1467.00
IUUC-Cfa-020112 Canis familiaris 93.98 0.00e+00 2175.00
IUUC-Cpo-022152 Cavia porcellus 83.95 0.00e+00 2016.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 41.84 3.00e-40 160.00
IUUC-Csa-023504 Chlorocebus sabaeus 88.46 0.00e+00 2081.00
IUUC-Cho-024780 Choloepus hoffmanni 79.45 0.00e+00 697.00
IUUC-Cin-025276 Ciona intestinalis 42.26 5.00e-113 401.00
IUUC-Csv-026283 Ciona savignyi 44.58 8.00e-116 410.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 28.12 5.00e-90 326.00
IUUC-Cne-027079 Cryptococcus neoformans 33.86 2.00e-77 285.00
IUUC-Cme-027346 Cyanidioschyzon merolae 27.46 3.00e-46 181.00
IUUC-Dre-028073 Danio rerio 49.17 0.00e+00 1023.00
IUUC-Dno-030038 Dasypus novemcinctus 83.44 0.00e+00 1937.00
IUUC-Dor-031100 Dipodomys ordii 83.88 0.00e+00 1519.00
IUUC-Dse-031310 Dothistroma septosporum 29.44 4.00e-86 313.00
IUUC-Dme-031991 Drosophila melanogaster 41.62 2.00e-112 400.00
IUUC-Ete-033082 Echinops telfairi 77.33 0.00e+00 1437.00
IUUC-Eca-033471 Equus caballus 89.46 0.00e+00 2078.00
IUUC-Eeu-034993 Erinaceus europaeus 83.77 0.00e+00 1300.00
IUUC-Fal-036973 Ficedula albicollis 77.20 0.00e+00 1689.00
IUUC-Fox-037677 Fusarium oxysporum 30.98 2.00e-89 323.00
IUUC-Fso-038252 Fusarium solani 31.42 2.00e-92 334.00
IUUC-Gmo-039669 Gadus morhua 60.46 4.00e-173 602.00
IUUC-Ggr-039988 Gaeumannomyces graminis 29.97 4.00e-86 313.00
IUUC-Gga-040423 Gallus gallus 77.31 0.00e+00 1760.00
IUUC-Gac-042134 Gasterosteus aculeatus 53.25 0.00e+00 805.00
IUUC-Gma-042929 Glycine max 32.58 2.00e-89 324.00
IUUC-Ggo-044528 Gorilla gorilla 88.46 0.00e+00 2079.00
IUUC-Hsa-046259 Homo sapiens 88.46 0.00e+00 2053.00
IUUC-Hvu-047139 Hordeum vulgare 36.24 8.00e-59 221.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 86.87 0.00e+00 2039.00
IUUC-Kpa-049169 Komagataella pastoris 29.94 3.00e-63 236.00
IUUC-Lch-050471 Latimeria chalumnae 65.88 0.00e+00 1472.00
IUUC-Lpe-050800 Leersia perrieri 33.39 7.00e-89 322.00
IUUC-Loc-052320 Lepisosteus oculatus 47.33 0.00e+00 877.00
IUUC-Lma-053149 Leptosphaeria maculans 30.13 7.00e-86 312.00
IUUC-Laf-053810 Loxodonta africana 83.82 0.00e+00 1886.00
IUUC-Mcc-055574 Macaca mulatta 88.04 0.00e+00 2028.00
IUUC-Meu-055945 Macropus eugenii 68.12 0.00e+00 1071.00
IUUC-Mor-057195 Magnaporthe oryzae 30.63 6.00e-92 332.00
IUUC-Mpo-057488 Magnaporthe poae 31.78 6.00e-86 312.00
IUUC-Mtr-057955 Medicago truncatula 36.52 1.00e-91 331.00
IUUC-Mla-059027 Melampsora laricipopulina 35.79 2.00e-80 293.00
IUUC-Mga-060156 Meleagris gallopavo 77.31 0.00e+00 1780.00
IUUC-Mvi-060398 Microbotryum violaceum 36.48 8.00e-82 299.00
IUUC-Mmr-061113 Microcebus murinus 89.88 0.00e+00 2076.00
IUUC-Mdo-063001 Monodelphis domestica 81.78 0.00e+00 1900.00
IUUC-Mmu-063180 Mus musculus 82.53 0.00e+00 1897.00
IUUC-Mac-065551 Musa acuminata 37.36 2.00e-54 206.00
IUUC-Mpu-066525 Mustela putorius furo 92.56 0.00e+00 2141.00
IUUC-Mlu-067877 Myotis lucifugus 89.21 0.00e+00 2039.00
IUUC-Nfi-068418 Neosartorya fischeri 31.59 3.00e-84 306.00
IUUC-Ncr-068648 Neurospora crassa 31.29 1.00e-87 318.00
IUUC-Nle-069959 Nomascus leucogenys 89.55 0.00e+00 2056.00
IUUC-Opr-070522 Ochotona princeps 79.58 0.00e+00 1056.00
IUUC-Ont-072293 Oreochromis niloticus 49.03 0.00e+00 799.00
IUUC-Oan-073519 Ornithorhynchus anatinus 79.70 0.00e+00 1813.00
IUUC-Ocu-074492 Oryctolagus cuniculus 83.64 0.00e+00 1814.00
IUUC-Oba-075567 Oryza barthii 32.02 1.00e-91 332.00
IUUC-Obr-076332 Oryza brachyantha 36.17 2.00e-86 313.00
IUUC-Ogl-077348 Oryza glaberrima 32.02 2.00e-91 331.00
IUUC-Ogu-078779 Oryza glumaepatula 31.88 2.00e-91 331.00
IUUC-Oin-079738 Oryza indica 29.95 2.00e-80 293.00
IUUC-Olo-080701 Oryza longistaminata 30.00 9.00e-81 295.00
IUUC-Ome-081708 Oryza meridionalis 32.87 9.00e-88 318.00
IUUC-Oni-082251 Oryza nivara 31.72 1.00e-88 321.00
IUUC-Opu-083528 Oryza punctata 30.76 7.00e-83 302.00
IUUC-Oru-084293 Oryza rufipogon 31.34 1.00e-86 314.00
IUUC-Osa-085549 Oryza sativa 32.02 3.00e-91 330.00
IUUC-Ola-086793 Oryzias latipes 50.05 0.00e+00 831.00
IUUC-Olu-087786 Ostreococcus lucimarinus 29.83 1.00e-62 234.00
IUUC-Oga-089006 Otolemur garnettii 88.09 0.00e+00 2038.00
IUUC-Oar-089597 Ovis aries 82.21 0.00e+00 1897.00
IUUC-Ptr-091520 Pan troglodytes 88.29 0.00e+00 2046.00
IUUC-Pan-092333 Papio anubis 88.71 0.00e+00 2016.00
IUUC-Psi-094004 Pelodiscus sinensis 78.64 0.00e+00 1825.00
IUUC-Pma-094128 Petromyzon marinus 54.37 5.00e-94 338.00
IUUC-Pno-094849 Phaeosphaeria nodorum 29.07 3.00e-81 296.00
IUUC-Ppa-095714 Physcomitrella patens 30.75 1.00e-91 331.00
IUUC-Pfo-096569 Poecilia formosa 52.55 0.00e+00 809.00
IUUC-Pab-097960 Pongo abelii 87.88 0.00e+00 2038.00
IUUC-Pop-098921 Populus trichocarpa 36.59 2.00e-84 307.00
IUUC-Pca-100509 Procavia capensis 71.53 0.00e+00 1188.00
IUUC-Ppe-101730 Prunus persica 36.30 9.00e-92 332.00
IUUC-Pva-102142 Pteropus vampyrus 85.95 0.00e+00 1986.00
IUUC-Pgr-103446 Puccinia graminis 31.16 5.00e-69 256.00
IUUC-Ptt-103849 Puccinia triticina 30.18 4.00e-71 263.00
IUUC-Pte-104128 Pyrenophora teres 30.55 1.00e-83 305.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 31.70 7.00e-83 301.00
IUUC-Rno-104871 Rattus norvegicus 79.62 0.00e+00 1835.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.32 4.00e-42 166.00
IUUC-Sha-106962 Sarcophilus harrisii 81.51 0.00e+00 1881.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 32.56 3.00e-66 246.00
IUUC-Spo-108170 Schizosaccharomyces pombe 34.71 2.00e-65 244.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 34.59 3.00e-87 317.00
IUUC-Smo-109554 Selaginella moellendorffii 36.67 1.00e-85 311.00
IUUC-Sit-110479 Setaria italica 34.76 4.00e-71 263.00
IUUC-Sly-111752 Solanum lycopersicum 35.07 2.00e-91 330.00
IUUC-Sar-113304 Sorex araneus 86.84 0.00e+00 1988.00
IUUC-Sbi-114196 Sorghum bicolor 35.67 1.00e-72 268.00
IUUC-Sre-115151 Sporisorium reilianum 31.05 2.00e-85 311.00
IUUC-Ssc-116104 Sus scrofa 87.90 0.00e+00 2016.00
IUUC-Tgu-117438 Taeniopygia guttata 77.64 0.00e+00 1754.00
IUUC-Tru-118553 Takifugu rubripes 46.81 0.00e+00 920.00
IUUC-Tsy-119056 Tarsius syrichta 86.26 0.00e+00 1895.00
IUUC-Tni-119933 Tetraodon nigroviridis 46.06 0.00e+00 719.00
IUUC-Tca-121376 Theobroma cacao 31.31 3.00e-104 373.00
IUUC-Tre-121972 Trichoderma reesei 34.66 7.00e-80 292.00
IUUC-Tvi-122342 Trichoderma virens 30.64 3.00e-80 293.00
IUUC-Tae-123898 Triticum aestivum 33.91 5.00e-91 329.00
IUUC-Tur-126735 Triticum urartu 30.33 1.00e-35 145.00
IUUC-Tme-126999 Tuber melanosporum 33.60 5.00e-82 300.00
IUUC-Tbe-127280 Tupaia belangeri 89.52 1.00e-143 504.00
IUUC-Ttr-129104 Tursiops truncatus 87.29 0.00e+00 1996.00
IUUC-Uma-129562 Ustilago maydis 30.91 3.00e-84 307.00
IUUC-Vda-129862 Verticillium dahliae 30.50 5.00e-90 326.00
IUUC-Vpa-130819 Vicugna pacos 84.32 0.00e+00 981.00
IUUC-Vvi-131111 Vitis vinifera 35.33 1.00e-85 311.00
IUUC-Xtr-132629 Xenopus tropicalis 61.56 0.00e+00 1331.00
IUUC-Xma-134065 Xiphophorus maculatus 52.03 0.00e+00 803.00
IUUC-Yli-134633 Yarrowia lipolytica 32.54 2.00e-63 238.00
IUUC-Zma-135176 Zea mays 36.09 1.00e-86 314.00
Created Date 25-Jun-2017

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