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Tag Content
UUCD2 ID IUUC-Pab-097622
UUCD1 version UUC-PoA-00221
Ensembl Protein ID ENSPPYP00000006296.2
UniProt Accession H2NKD8; H2NKD8_PONAB
Genbank Protein ID ENSPPYP00000006296
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01365243
Gene Name CUL4A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000005523.2 ENSPPYT00000006544.2 ENSPPYP00000006296.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 2.50e-220 733.4 65 660
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkif 87
           kl+eav+++++++s+++++eely+av+nlc++kv+ +lYk+l++++e+++ +q+   +e+s d+  +Lk++n++W+++++q+ ++r+if
   Q: 65   KLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVqAQILPFREDSLDSVlFLKKINTCWQDHCRQMIMIRSIF 153
           5899**********************************************99************************************* PP
   S: 88   ayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfle 174
           ++ldrtyv +++++ ++++++l+l+r++i++d  +++++++ +l lie+eR+geavdr+ll+++  +l++L     ++yk+sFE kfle
   Q: 154  LFLDRTYVLQNSTLPSIWDMGLELFRTHIISDkmVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDL-----QVYKDSFELKFLE 237
           *******************************************************************9998.....9************ PP
   S: 175  atqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLl 262
           +t+ +y+ e ++++qe+ev eYl++v +rl+ee +r+ +yl++st+++L+++vek+l+ +hl+++l ++l++ll++++  dl++my+Ll
   Q: 238  ETNCLYASEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILqKGLDHLLDENRVPDLAQMYQLL 326
           ****************************************************************9989********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.E 350
           srv+ g + ll++++++ik+ g+a+++++ek+kd   +V++ll++k+k++++++ +F+++++F++ ++++fetf+nk+     +++p E
   Q: 327  SRVRGGQQVLLQHWSEYIKTFGTAIVINPEKDKD---MVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKR-----PNKPaE 407
           **********************************...*****************************************.....66666* PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           l+A+++D++Lr+++k++t+eele++ldk++++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+
   Q: 408  LIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFK 496
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkk 528
           d+++S+d++ +Fk++++n+++s  ++l+v++L++g+Wpt++ +e v+L++e+ k++e f++fYl khsgRkLqWq+tlg+a lkae+k+
   Q: 497  DMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPME-VHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKE 584
           ****************************************9999.******************************************** PP
   S: 529  gkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           gk+e+qVs fQ++vLL+fn+ + +s+ee+k+at+++++eLrrtlqsL+++k++vl k+p++ke+e++d+f++N ef
   Q: 585  GKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEF 660
           *************************************************************************998 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MADEAPRKGS FSALVGRTNG LTKPAALAAA PAKPGGAGGS KKLVIKNFRD RPRLPDNYTQ 60
DTWRKLHEAV RAVQSSTSIR YNLEELYQAV ENLCSHKVSP MLYKQLRQAC EDHVQAQILP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-097622|E3,Cullin|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCACGCGGGC GGGGCGGGGC GCGCGAGGAG GACGGGCAAA AGCCGCGCGG ACCGGGGCGG 60
GCGGAGCGGA GCTGGGCGGG CGGCGGCGCT CGGGGCGGGG CGCGGCCCTT TTAGGCCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-097622|E3,Cullin|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0030097--P:hemopoiesis
GO:0001701--P:in utero embryonic development
GO:0030853--P:negative regulation of granulocyte differentiation
GO:0008284--P:positive regulation of cell proliferation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:2000001--P:regulation of DNA damage checkpoint
GO:2000819--P:regulation of nucleotide-excision repair
GO:0051246--P:regulation of protein metabolic process
GO:0035019--P:somatic stem cell population maintenance
KEGG pon:100453992
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000285 Aegilops tauschii 56.20 0.00e+00 821.00
IUUC-Aml-001592 Ailuropoda melanoleuca 92.93 0.00e+00 1362.00
IUUC-Atr-002727 Amborella trichopoda 58.78 0.00e+00 806.00
IUUC-Apl-003269 Anas platyrhynchos 91.55 0.00e+00 1324.00
IUUC-Aly-006547 Arabidopsis lyrata 58.31 0.00e+00 808.00
IUUC-Ath-006748 Arabidopsis thaliana 58.03 0.00e+00 799.00
IUUC-Acl-008359 Aspergillus clavatus 36.88 4.00e-125 442.00
IUUC-Afl-008567 Aspergillus flavus 39.42 5.00e-139 488.00
IUUC-Afu-008833 Aspergillus fumigatus 38.85 2.00e-133 469.00
IUUC-Ani-009373 Aspergillus nidulans 40.05 3.00e-139 489.00
IUUC-Ang-009622 Aspergillus niger 39.31 1.00e-138 487.00
IUUC-Aor-010241 Aspergillus oryzae 39.17 8.00e-136 477.00
IUUC-Ate-010251 Aspergillus terreus 40.34 1.00e-143 503.00
IUUC-Ame-011580 Astyanax mexicanus 84.87 0.00e+00 1247.00
IUUC-Bgr-012219 Blumeria graminis 37.05 4.00e-117 415.00
IUUC-Bta-012355 Bos taurus 93.61 0.00e+00 1372.00
IUUC-Bci-013744 Botrytis cinerea 39.87 2.00e-131 462.00
IUUC-Bdi-014223 Brachypodium distachyon 56.20 0.00e+00 818.00
IUUC-Bol-016544 Brassica oleracea 58.17 0.00e+00 824.00
IUUC-Bra-017794 Brassica rapa 58.45 0.00e+00 828.00
IUUC-Cja-019861 Callithrix jacchus 98.74 0.00e+00 1436.00
IUUC-Cfa-021009 Canis familiaris 93.17 0.00e+00 1422.00
IUUC-Cpo-021867 Cavia porcellus 94.33 0.00e+00 1430.00
IUUC-Cre-022739 Chlamydomonas reinhardtii 47.30 3.00e-175 608.00
IUUC-Csa-024139 Chlorocebus sabaeus 99.21 0.00e+00 1472.00
IUUC-Cho-024899 Choloepus hoffmanni 96.63 0.00e+00 1013.00
IUUC-Cin-025727 Ciona intestinalis 62.38 0.00e+00 763.00
IUUC-Csv-026117 Ciona savignyi 54.02 0.00e+00 867.00
IUUC-Cgl-026761 Colletotrichum gloeosporioides 38.87 3.00e-125 442.00
IUUC-Cme-027355 Cyanidioschyzon merolae 34.14 8.00e-118 417.00
IUUC-Dno-028879 Dasypus novemcinctus 86.70 0.00e+00 1329.00
IUUC-Dor-030698 Dipodomys ordii 94.60 0.00e+00 1410.00
IUUC-Dse-031159 Dothistroma septosporum 36.11 1.00e-120 427.00
IUUC-Dme-031652 Drosophila melanogaster 66.76 0.00e+00 951.00
IUUC-Ete-033101 Echinops telfairi 88.90 0.00e+00 1268.00
IUUC-Eca-033696 Equus caballus 93.36 0.00e+00 1369.00
IUUC-Fca-036333 Felis catus 94.09 0.00e+00 1365.00
IUUC-Fal-036995 Ficedula albicollis 91.52 0.00e+00 1342.00
IUUC-Fox-037854 Fusarium oxysporum 39.43 2.00e-126 446.00
IUUC-Fso-038138 Fusarium solani 39.33 2.00e-130 459.00
IUUC-Gmo-038754 Gadus morhua 84.05 0.00e+00 1233.00
IUUC-Ggr-040003 Gaeumannomyces graminis 36.32 1.00e-104 374.00
IUUC-Gga-040358 Gallus gallus 88.79 0.00e+00 1365.00
IUUC-Gac-041555 Gasterosteus aculeatus 85.46 0.00e+00 1246.00
IUUC-Gma-043960 Glycine max 59.15 0.00e+00 844.00
IUUC-Ggo-045110 Gorilla gorilla 85.38 0.00e+00 1196.00
IUUC-Hsa-045679 Homo sapiens 99.47 0.00e+00 1473.00
IUUC-Itr-048182 Ictidomys tridecemlineatus 94.51 0.00e+00 1296.00
IUUC-Lch-050417 Latimeria chalumnae 86.56 0.00e+00 1329.00
IUUC-Lpe-051446 Leersia perrieri 56.82 0.00e+00 822.00
IUUC-Loc-051804 Lepisosteus oculatus 83.38 0.00e+00 1254.00
IUUC-Lma-053080 Leptosphaeria maculans 36.29 6.00e-128 451.00
IUUC-Laf-054100 Loxodonta africana 93.61 0.00e+00 1366.00
IUUC-Mcc-055168 Macaca mulatta 98.94 0.00e+00 1315.00
IUUC-Meu-056492 Macropus eugenii 73.48 4.00e-171 594.00
IUUC-Mor-057102 Magnaporthe oryzae 35.39 1.00e-117 417.00
IUUC-Mpo-057342 Magnaporthe poae 36.97 1.00e-102 367.00
IUUC-Mtr-058660 Medicago truncatula 57.76 0.00e+00 819.00
IUUC-Mla-058936 Melampsora laricipopulina 39.58 3.00e-113 402.00
IUUC-Mga-059866 Meleagris gallopavo 91.85 0.00e+00 1332.00
IUUC-Mvi-060455 Microbotryum violaceum 41.78 1.00e-141 497.00
IUUC-Mmr-061551 Microcebus murinus 94.73 0.00e+00 1417.00
IUUC-Mdo-062215 Monodelphis domestica 90.98 0.00e+00 1400.00
IUUC-Mmu-063402 Mus musculus 94.60 0.00e+00 1427.00
IUUC-Mac-064443 Musa acuminata 56.53 0.00e+00 828.00
IUUC-Mpu-066383 Mustela putorius furo 93.83 0.00e+00 1362.00
IUUC-Mlu-067450 Myotis lucifugus 89.27 0.00e+00 1338.00
IUUC-Nfi-068363 Neosartorya fischeri 38.95 2.00e-134 473.00
IUUC-Ncr-068950 Neurospora crassa 36.46 2.00e-120 427.00
IUUC-Nle-069606 Nomascus leucogenys 99.34 0.00e+00 1473.00
IUUC-Opr-070671 Ochotona princeps 84.05 2.00e-116 412.00
IUUC-Ont-071562 Oreochromis niloticus 79.81 0.00e+00 1214.00
IUUC-Oan-073299 Ornithorhynchus anatinus 88.41 0.00e+00 1352.00
IUUC-Ocu-074731 Oryctolagus cuniculus 94.47 0.00e+00 1436.00
IUUC-Oba-075198 Oryza barthii 56.82 0.00e+00 822.00
IUUC-Obr-076095 Oryza brachyantha 56.62 0.00e+00 822.00
IUUC-Ogl-077032 Oryza glaberrima 56.82 0.00e+00 823.00
IUUC-Ogu-078051 Oryza glumaepatula 56.82 0.00e+00 822.00
IUUC-Oin-079399 Oryza indica 60.30 0.00e+00 724.00
IUUC-Olo-080988 Oryza longistaminata 55.97 0.00e+00 812.00
IUUC-Ome-081600 Oryza meridionalis 55.97 0.00e+00 812.00
IUUC-Oni-082623 Oryza nivara 56.11 0.00e+00 813.00
IUUC-Opu-083762 Oryza punctata 55.98 0.00e+00 814.00
IUUC-Oru-084499 Oryza rufipogon 56.82 0.00e+00 822.00
IUUC-Ola-087157 Oryzias latipes 84.92 0.00e+00 1236.00
IUUC-Olu-087650 Ostreococcus lucimarinus 48.43 0.00e+00 627.00
IUUC-Oar-089346 Ovis aries 92.76 0.00e+00 1359.00
IUUC-Ptr-091177 Pan troglodytes 99.47 0.00e+00 1473.00
IUUC-Pan-092191 Papio anubis 98.56 0.00e+00 1462.00
IUUC-Pma-094678 Petromyzon marinus 78.63 0.00e+00 969.00
IUUC-Pno-094946 Phaeosphaeria nodorum 36.46 2.00e-110 393.00
IUUC-Ppa-095688 Physcomitrella patens 60.22 0.00e+00 880.00
IUUC-Pca-100391 Procavia capensis 84.46 0.00e+00 999.00
IUUC-Ppe-101142 Prunus persica 57.89 0.00e+00 821.00
IUUC-Pgr-103334 Puccinia graminis 36.86 9.00e-107 381.00
IUUC-Ptt-103903 Puccinia triticina 40.27 2.00e-96 347.00
IUUC-Pte-104167 Pyrenophora teres 36.08 2.00e-128 452.00
IUUC-Pyt-104736 Pyrenophora triticirepentis 35.90 2.00e-127 449.00
IUUC-Rno-105829 Rattus norvegicus 94.47 0.00e+00 1431.00
IUUC-Sha-106762 Sarcophilus harrisii 93.19 0.00e+00 1325.00
IUUC-Sja-107940 Schizosaccharomyces japonicus 33.93 7.00e-110 391.00
IUUC-Spo-108109 Schizosaccharomyces pombe 32.39 5.00e-106 378.00
IUUC-Ssl-108537 Sclerotinia sclerotiorum 39.22 2.00e-129 456.00
IUUC-Smo-109313 Selaginella moellendorffii 59.92 0.00e+00 884.00
IUUC-Sit-110626 Setaria italica 56.54 0.00e+00 819.00
IUUC-Sly-111497 Solanum lycopersicum 58.82 0.00e+00 845.00
IUUC-Sbi-113931 Sorghum bicolor 56.26 0.00e+00 818.00
IUUC-Sre-114943 Sporisorium reilianum 38.75 3.00e-132 465.00
IUUC-Ssc-116133 Sus scrofa 91.98 0.00e+00 1375.00
IUUC-Tgu-116961 Taeniopygia guttata 91.12 0.00e+00 1337.00
IUUC-Tsy-119517 Tarsius syrichta 88.83 0.00e+00 648.00
IUUC-Tca-121626 Theobroma cacao 58.47 0.00e+00 833.00
IUUC-Tre-121907 Trichoderma reesei 39.66 1.00e-132 466.00
IUUC-Tvi-122568 Trichoderma virens 39.12 9.00e-132 464.00
IUUC-Tae-123442 Triticum aestivum 56.20 0.00e+00 820.00
IUUC-Tur-126032 Triticum urartu 56.20 0.00e+00 820.00
IUUC-Tme-127162 Tuber melanosporum 41.12 5.00e-141 495.00
IUUC-Ttr-128326 Tursiops truncatus 88.79 0.00e+00 1182.00
IUUC-Uma-129531 Ustilago maydis 39.58 1.00e-113 404.00
IUUC-Vda-129701 Verticillium dahliae 39.35 6.00e-135 474.00
IUUC-Vvi-131133 Vitis vinifera 58.64 0.00e+00 849.00
IUUC-Xtr-132761 Xenopus tropicalis 81.54 0.00e+00 1253.00
IUUC-Zma-135529 Zea mays 56.40 0.00e+00 819.00
Created Date 25-Jun-2017

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