iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097835

Ensembl Protein ID

ENSPPYP00000003469.2

UniProt Accession

H2NCN3; H2NCN3_PONAB

Genbank Protein ID

ENSPPYP00000003469

Protein Name

Coronin

Genbank Nucleotide ID

ABGA01403639

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000002992.2	ENSPPYT00000003592.2	ENSPPYP00000003469.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.10e-17	60.8	101	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 101  GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 133
           8***********977799*************75 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

GRDPEPPEAG AAAPCAPGAL DMSFRKVVRQ SKFRHVFGQP VKNDQCYEDI RVSRVTWDST 60
FCAVNPKFLA VIVEASGGGA FLVLPLSKTG RIDKAYPMVC GHTGPVLDID WCPHNDEVIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCCGGGAT CCGGAGCCGC CCGAAGCCGG TGCCGCAGCC CCCTGCGCCC CCGGTGCTCT 60
CGGTGAGCGC GGCAGGGCCG GGGCTAGGGG CGCGGGCTGG GGGCTGGGCG GGGCTGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	93.87	0.00e+00	939.00
IUUC-Aca-005056	Anolis carolinensis	81.02	0.00e+00	811.00
IUUC-Ago-007901	Ashbya gossypii	40.29	8.00e-88	318.00
IUUC-Acl-008280	Aspergillus clavatus	41.48	8.00e-92	331.00
IUUC-Afl-008393	Aspergillus flavus	41.44	9.00e-91	327.00
IUUC-Afu-008865	Aspergillus fumigatus	40.24	1.00e-88	320.00
IUUC-Ani-009155	Aspergillus nidulans	41.44	2.00e-91	330.00
IUUC-Ang-009523	Aspergillus niger	39.90	2.00e-83	303.00
IUUC-Aor-010049	Aspergillus oryzae	40.91	1.00e-87	317.00
IUUC-Ate-010368	Aspergillus terreus	41.90	5.00e-88	318.00
IUUC-Ame-011256	Astyanax mexicanus	81.82	0.00e+00	723.00
IUUC-Bgr-011990	Blumeria graminis	41.90	4.00e-94	338.00
IUUC-Bta-012984	Bos taurus	92.40	0.00e+00	931.00
IUUC-Bci-013935	Botrytis cinerea	41.40	2.00e-93	336.00
IUUC-Cel-018669	Caenorhabditis elegans	52.11	1.00e-114	407.00
IUUC-Cja-019498	Callithrix jacchus	98.37	0.00e+00	956.00
IUUC-Cfa-020937	Canis familiaris	97.19	0.00e+00	870.00
IUUC-Cpo-021866	Cavia porcellus	89.57	0.00e+00	894.00
IUUC-Csa-023561	Chlorocebus sabaeus	98.16	0.00e+00	964.00
IUUC-Csv-026184	Ciona savignyi	40.74	2.00e-85	309.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	40.80	2.00e-91	330.00
IUUC-Cne-026773	Cryptococcus neoformans	36.21	4.00e-80	292.00
IUUC-Dre-028124	Danio rerio	72.05	0.00e+00	763.00
IUUC-Dno-029770	Dasypus novemcinctus	87.37	0.00e+00	871.00
IUUC-Dor-030989	Dipodomys ordii	91.82	0.00e+00	907.00
IUUC-Dme-032091	Drosophila melanogaster	53.85	2.00e-151	528.00
IUUC-Ete-032839	Echinops telfairi	66.80	0.00e+00	691.00
IUUC-Eca-033901	Equus caballus	94.48	0.00e+00	928.00
IUUC-Fca-036494	Felis catus	94.27	0.00e+00	912.00
IUUC-Fal-036737	Ficedula albicollis	82.65	0.00e+00	836.00
IUUC-Fox-037737	Fusarium oxysporum	41.15	1.00e-86	313.00
IUUC-Fso-038184	Fusarium solani	41.50	4.00e-92	332.00
IUUC-Gmo-038678	Gadus morhua	69.92	0.00e+00	724.00
IUUC-Ggr-039956	Gaeumannomyces graminis	41.50	2.00e-92	333.00
IUUC-Gac-041543	Gasterosteus aculeatus	70.95	0.00e+00	712.00
IUUC-Ggo-045035	Gorilla gorilla	99.39	0.00e+00	971.00
IUUC-Hsa-046154	Homo sapiens	99.18	0.00e+00	969.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	93.46	0.00e+00	908.00
IUUC-Lch-050453	Latimeria chalumnae	69.03	0.00e+00	738.00
IUUC-Loc-052911	Lepisosteus oculatus	69.92	0.00e+00	741.00
IUUC-Lma-053160	Leptosphaeria maculans	40.40	2.00e-90	327.00
IUUC-Laf-054566	Loxodonta africana	92.43	0.00e+00	895.00
IUUC-Mcc-054879	Macaca mulatta	98.36	0.00e+00	964.00
IUUC-Mor-056978	Magnaporthe oryzae	41.65	8.00e-93	334.00
IUUC-Mpo-057410	Magnaporthe poae	41.75	8.00e-87	314.00
IUUC-Mmr-060910	Microcebus murinus	92.84	0.00e+00	925.00
IUUC-Mmu-063455	Mus musculus	94.27	0.00e+00	932.00
IUUC-Mpu-066350	Mustela putorius furo	93.87	0.00e+00	924.00
IUUC-Mlu-067353	Myotis lucifugus	93.63	0.00e+00	927.00
IUUC-Nfi-068476	Neosartorya fischeri	40.94	4.00e-91	328.00
IUUC-Ncr-068781	Neurospora crassa	40.05	1.00e-94	340.00
IUUC-Nle-069161	Nomascus leucogenys	99.18	0.00e+00	964.00
IUUC-Opr-071106	Ochotona princeps	91.62	0.00e+00	900.00
IUUC-Ont-072629	Oreochromis niloticus	70.75	0.00e+00	748.00
IUUC-Ola-086558	Oryzias latipes	72.20	0.00e+00	761.00
IUUC-Oga-088805	Otolemur garnettii	93.87	0.00e+00	937.00
IUUC-Ptr-091484	Pan troglodytes	98.77	0.00e+00	964.00
IUUC-Pan-091843	Papio anubis	97.96	0.00e+00	958.00
IUUC-Pno-094994	Phaeosphaeria nodorum	41.40	1.00e-89	323.00
IUUC-Pfo-097309	Poecilia formosa	70.54	0.00e+00	755.00
IUUC-Pca-100411	Procavia capensis	82.00	0.00e+00	793.00
IUUC-Pva-102659	Pteropus vampyrus	94.68	0.00e+00	938.00
IUUC-Pte-104194	Pyrenophora teres	40.69	5.00e-90	325.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	40.69	6.00e-90	325.00
IUUC-Rno-106070	Rattus norvegicus	93.25	0.00e+00	927.00
IUUC-Sha-106609	Sarcophilus harrisii	94.08	0.00e+00	715.00
IUUC-Sja-107992	Schizosaccharomyces japonicus	40.45	2.00e-92	333.00
IUUC-Sre-114911	Sporisorium reilianum	35.70	7.00e-74	271.00
IUUC-Ssc-115980	Sus scrofa	90.74	0.00e+00	902.00
IUUC-Tru-118425	Takifugu rubripes	70.75	0.00e+00	744.00
IUUC-Tni-120610	Tetraodon nigroviridis	70.33	0.00e+00	743.00
IUUC-Tme-126924	Tuber melanosporum	39.95	2.00e-89	323.00
IUUC-Vda-129792	Verticillium dahliae	40.00	2.00e-90	326.00
IUUC-Vpa-130339	Vicugna pacos	81.98	5.00e-177	613.00
IUUC-Xtr-132873	Xenopus tropicalis	63.80	0.00e+00	671.00
IUUC-Xma-134047	Xiphophorus maculatus	71.16	0.00e+00	757.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence