iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004575

Ensembl Protein ID

ENSACAP00000006803.3

UniProt Accession

H9GC46; H9GC46_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006894.3	ENSACAT00000006953.3	ENSACAP00000006803.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-14	51.8	522	571

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy++  dde ++  G++++ i  e+ degW++g    +gk+GlfP+n+ve
   Q: 522  VALYDYQGDGDDEISFLPGETITDI--EQIDEGWWRG--RCNGKEGLFPANYVE 571
           58**********************9..99********..8************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MCFLLLLCSI HALRSKVSEE HEVLKKKELE TAPKASYGYG GKFGTEKDRM DKSALGHEYV 60
AEVGMHSSQT DAAKGFGGKF GVQKDRADKS ALGFDYKGEV DKHTSQKDYA VGFGGKYGVQ 120

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Nucleotide Sequence
(Fasta)

GCAGAAGTCT CAGAATAGCA AATAAGAGGG AGGTCAAAGG GCAAAGAAAT GCCTTCATGT 60
CATGCTATTA AAAGAGTCTG CTGAGAGGGA AATCTTTGTC AAAGCAATTC CCTCACTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cgl-026571	Colletotrichum gloeosporioides	56.25	2.00e-10	60.80
IUUC-Dse-031182	Dothistroma septosporum	38.24	2.00e-12	68.20
IUUC-Ete-033160	Echinops telfairi	37.06	3.00e-56	212.00
IUUC-Gmo-039044	Gadus morhua	43.48	5.00e-16	78.60
IUUC-Mpo-057325	Magnaporthe poae	54.90	7.00e-11	59.70
IUUC-Pno-095096	Phaeosphaeria nodorum	58.62	6.00e-14	72.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence