iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001698.4	ENSCAFT00000002660.4	ENSCAFP00000002468.3
ENSCAFG00000001698.4	ENSCAFT00000049288.1	ENSCAFP00000039332.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-25	87.9	150	180
UBD/Beta-Prp	3.00e-64	217.3	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 150  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 180
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwd 80
           ++l gh+ +v   v+   p +  +++ srd+t+++w  ++        ++++sgh+++v++v+++p+++     +++tg++D++i++++
   Q: 12   CSLPGHELDVRGLVCSlYPPGA-FVSVSRDRTTRLWVPDSRPNrgfteMHCMSGHSNFVSCVCIIPSSDmyphgLIATGGNDHNICIFS 99
           6677888888888888566665.888899*******988765578999***************************************** PP
   S: 81   lstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           l+++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g
   Q: 100  LESPAPLYILKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAG 182
           ***********************9.9***************..9******.*********************************..88* PP
   S: 170  kllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
           ++ rt++g h+d v+ l++ s+  e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn   +v++++D+s+riW  ++g++ +
   Q: 183  RCERTFSG-HEDCVRGLAILSE-AEFLSCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW--KHGECAQ 266
           *******9.*********9997.7****************.***************************************..9****** PP
   S: 259  tlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           t+ l+++s+++++v  +++  +v g++d++++++  +++
   Q: 267  TIRLPAQSIWCCCV--LDNGDIVVGASDGIIRVFTESED 303
           **************..9999*************987665 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MASSAARYRL SCSLPGHELD VRGLVCSLYP PGAFVSVSRD RTTRLWVPDS RPNRGFTEMH 60
CMSGHSNFVS CVCIIPSSDM YPHGLIATGG NDHNICIFSL ESPAPLYILK GHKNTVCSLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAGCA GCGCTGCCAG GTACCGGCTG AGCTGCTCGC TCCCGGGCCA CGAGCTGGAC 60
GTGCGGGGCC TAGTGTGCAG CCTCTATCCG CCGGGGGCCT TTGTGTCCGT GTCCCGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR016024--ARM-type_fold
IPR003143--Cyt_cd1_C
IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	31.30	8.00e-91	328.00
IUUC-Aml-002125	Ailuropoda melanoleuca	98.62	0.00e+00	1635.00
IUUC-Atr-002554	Amborella trichopoda	30.73	7.00e-96	345.00
IUUC-Apl-004094	Anas platyrhynchos	81.73	0.00e+00	1263.00
IUUC-Aca-004726	Anolis carolinensis	80.50	0.00e+00	1317.00
IUUC-Aly-005961	Arabidopsis lyrata	33.38	6.00e-108	385.00
IUUC-Ath-006639	Arabidopsis thaliana	32.90	6.00e-103	368.00
IUUC-Ago-007772	Ashbya gossypii	29.59	3.00e-79	289.00
IUUC-Acl-008316	Aspergillus clavatus	31.94	9.00e-88	318.00
IUUC-Afl-008532	Aspergillus flavus	33.33	3.00e-90	326.00
IUUC-Afu-008950	Aspergillus fumigatus	32.58	4.00e-91	329.00
IUUC-Ani-009186	Aspergillus nidulans	33.42	5.00e-94	338.00
IUUC-Ang-009575	Aspergillus niger	31.50	3.00e-87	316.00
IUUC-Aor-010086	Aspergillus oryzae	33.33	3.00e-90	326.00
IUUC-Ate-010541	Aspergillus terreus	31.09	3.00e-86	313.00
IUUC-Ame-011633	Astyanax mexicanus	66.87	0.00e+00	1122.00
IUUC-Bgr-012292	Blumeria graminis	30.63	9.00e-93	334.00
IUUC-Bta-013218	Bos taurus	95.25	0.00e+00	1585.00
IUUC-Bci-013876	Botrytis cinerea	32.03	5.00e-94	338.00
IUUC-Bdi-014810	Brachypodium distachyon	33.63	4.00e-105	375.00
IUUC-Bol-016006	Brassica oleracea	32.47	2.00e-105	377.00
IUUC-Bra-017593	Brassica rapa	32.86	2.00e-106	380.00
IUUC-Cel-018703	Caenorhabditis elegans	27.57	6.00e-72	265.00
IUUC-Cja-019270	Callithrix jacchus	94.62	0.00e+00	1565.00
IUUC-Cpo-021449	Cavia porcellus	88.04	0.00e+00	1431.00
IUUC-Csa-024140	Chlorocebus sabaeus	95.25	0.00e+00	1574.00
IUUC-Cho-024923	Choloepus hoffmanni	94.51	0.00e+00	762.00
IUUC-Cin-025373	Ciona intestinalis	39.80	6.00e-170	591.00
IUUC-Csv-026324	Ciona savignyi	41.76	0.00e+00	634.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	31.83	2.00e-87	316.00
IUUC-Cne-026998	Cryptococcus neoformans	30.91	2.00e-85	310.00
IUUC-Cme-027154	Cyanidioschyzon merolae	30.16	3.00e-55	209.00
IUUC-Dre-028674	Danio rerio	65.13	0.00e+00	1099.00
IUUC-Dno-028966	Dasypus novemcinctus	94.62	0.00e+00	1570.00
IUUC-Dor-030343	Dipodomys ordii	88.21	0.00e+00	903.00
IUUC-Dse-031385	Dothistroma septosporum	31.08	7.00e-83	301.00
IUUC-Dme-032044	Drosophila melanogaster	36.61	8.00e-125	441.00
IUUC-Ete-032506	Echinops telfairi	83.89	0.00e+00	825.00
IUUC-Eca-033547	Equus caballus	96.88	0.00e+00	1598.00
IUUC-Eeu-034462	Erinaceus europaeus	93.47	3.00e-141	495.00
IUUC-Fca-035893	Felis catus	97.12	0.00e+00	1603.00
IUUC-Fal-037235	Ficedula albicollis	82.02	0.00e+00	1369.00
IUUC-Fox-037836	Fusarium oxysporum	31.03	8.00e-94	338.00
IUUC-Fso-038251	Fusarium solani	31.30	2.00e-93	337.00
IUUC-Gmo-038648	Gadus morhua	65.98	0.00e+00	967.00
IUUC-Ggr-039867	Gaeumannomyces graminis	36.31	2.00e-74	273.00
IUUC-Gga-040989	Gallus gallus	80.15	0.00e+00	1320.00
IUUC-Gac-041344	Gasterosteus aculeatus	66.87	0.00e+00	1080.00
IUUC-Gma-043067	Glycine max	32.09	9.00e-105	374.00
IUUC-Ggo-045009	Gorilla gorilla	95.25	0.00e+00	1214.00
IUUC-Hsa-046807	Homo sapiens	95.50	0.00e+00	1574.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	96.00	0.00e+00	1587.00
IUUC-Kpa-049134	Komagataella pastoris	42.73	4.00e-89	322.00
IUUC-Lch-049597	Latimeria chalumnae	73.68	0.00e+00	744.00
IUUC-Lpe-050821	Leersia perrieri	31.66	3.00e-99	356.00
IUUC-Loc-051849	Lepisosteus oculatus	72.51	0.00e+00	1215.00
IUUC-Lma-053297	Leptosphaeria maculans	33.85	7.00e-103	368.00
IUUC-Laf-053495	Loxodonta africana	94.75	0.00e+00	1578.00
IUUC-Meu-055983	Macropus eugenii	82.25	0.00e+00	650.00
IUUC-Mor-057006	Magnaporthe oryzae	36.12	5.00e-74	272.00
IUUC-Mpo-057465	Magnaporthe poae	36.11	2.00e-73	270.00
IUUC-Mtr-058374	Medicago truncatula	33.13	7.00e-113	401.00
IUUC-Mla-058895	Melampsora laricipopulina	36.03	9.00e-78	284.00
IUUC-Mvi-060297	Microbotryum violaceum	35.64	9.00e-109	387.00
IUUC-Mmr-060810	Microcebus murinus	90.55	0.00e+00	1463.00
IUUC-Mdo-062671	Monodelphis domestica	87.27	0.00e+00	1430.00
IUUC-Mmu-063536	Mus musculus	93.38	0.00e+00	1523.00
IUUC-Mac-064902	Musa acuminata	31.65	3.00e-100	359.00
IUUC-Mpu-066085	Mustela putorius furo	98.38	0.00e+00	1627.00
IUUC-Mlu-067907	Myotis lucifugus	93.88	0.00e+00	1002.00
IUUC-Nfi-068457	Neosartorya fischeri	32.12	7.00e-74	271.00
IUUC-Ncr-068622	Neurospora crassa	30.31	4.00e-93	336.00
IUUC-Nle-069049	Nomascus leucogenys	94.50	0.00e+00	1544.00
IUUC-Opr-071013	Ochotona princeps	92.59	2.00e-104	373.00
IUUC-Ont-071339	Oreochromis niloticus	69.65	0.00e+00	1163.00
IUUC-Oan-073353	Ornithorhynchus anatinus	83.40	9.00e-113	399.00
IUUC-Ocu-074625	Oryctolagus cuniculus	95.00	0.00e+00	1576.00
IUUC-Oba-075226	Oryza barthii	28.89	6.00e-84	305.00
IUUC-Obr-076875	Oryza brachyantha	33.29	1.00e-109	390.00
IUUC-Ogl-077057	Oryza glaberrima	32.38	6.00e-109	388.00
IUUC-Ogu-078156	Oryza glumaepatula	32.34	4.00e-109	389.00
IUUC-Oin-079373	Oryza indica	32.01	3.00e-107	382.00
IUUC-Olo-080849	Oryza longistaminata	29.35	3.00e-73	270.00
IUUC-Ome-081654	Oryza meridionalis	28.62	2.00e-84	306.00
IUUC-Oni-082221	Oryza nivara	29.24	1.00e-87	317.00
IUUC-Opu-084103	Oryza punctata	29.54	2.00e-84	306.00
IUUC-Oru-084751	Oryza rufipogon	28.40	2.00e-83	303.00
IUUC-Osa-085584	Oryza sativa	32.10	1.00e-108	387.00
IUUC-Ola-086974	Oryzias latipes	68.58	0.00e+00	1165.00
IUUC-Oga-088052	Otolemur garnettii	90.76	0.00e+00	1480.00
IUUC-Oar-089509	Ovis aries	95.28	0.00e+00	1584.00
IUUC-Ptr-090911	Pan troglodytes	95.62	0.00e+00	1576.00
IUUC-Pan-092141	Papio anubis	95.38	0.00e+00	1587.00
IUUC-Psi-093543	Pelodiscus sinensis	83.04	0.00e+00	1286.00
IUUC-Pno-094952	Phaeosphaeria nodorum	33.51	6.00e-96	345.00
IUUC-Ppa-095881	Physcomitrella patens	32.31	3.00e-109	389.00
IUUC-Pfo-096739	Poecilia formosa	68.11	0.00e+00	1155.00
IUUC-Pab-098641	Pongo abelii	95.50	0.00e+00	1573.00
IUUC-Pop-099621	Populus trichocarpa	32.05	8.00e-104	371.00
IUUC-Pca-100599	Procavia capensis	85.31	0.00e+00	1310.00
IUUC-Ppe-101874	Prunus persica	31.97	7.00e-109	388.00
IUUC-Pva-103009	Pteropus vampyrus	92.69	0.00e+00	1291.00
IUUC-Pgr-103260	Puccinia graminis	32.57	3.00e-93	336.00
IUUC-Ptt-103711	Puccinia triticina	32.28	4.00e-91	328.00
IUUC-Pte-104337	Pyrenophora teres	32.78	2.00e-93	337.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	33.16	6.00e-95	342.00
IUUC-Rno-105273	Rattus norvegicus	94.12	0.00e+00	1563.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.44	8.00e-81	295.00
IUUC-Sha-106758	Sarcophilus harrisii	87.80	0.00e+00	1444.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.69	3.00e-96	346.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.34	1.00e-101	363.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	40.28	2.00e-91	330.00
IUUC-Smo-109368	Selaginella moellendorffii	30.66	1.00e-96	347.00
IUUC-Sit-109699	Setaria italica	33.94	3.00e-110	392.00
IUUC-Sly-111063	Solanum lycopersicum	32.64	4.00e-104	372.00
IUUC-Sar-113199	Sorex araneus	96.25	0.00e+00	818.00
IUUC-Sbi-114745	Sorghum bicolor	33.03	2.00e-101	363.00
IUUC-Sre-115080	Sporisorium reilianum	33.25	7.00e-105	375.00
IUUC-Ssc-115666	Sus scrofa	95.26	0.00e+00	1587.00
IUUC-Tgu-116877	Taeniopygia guttata	81.27	0.00e+00	1352.00
IUUC-Tru-117580	Takifugu rubripes	67.12	0.00e+00	1138.00
IUUC-Tsy-118946	Tarsius syrichta	95.46	0.00e+00	1457.00
IUUC-Tni-119755	Tetraodon nigroviridis	64.62	0.00e+00	1061.00
IUUC-Tca-120977	Theobroma cacao	31.42	5.00e-100	358.00
IUUC-Tre-122217	Trichoderma reesei	32.74	3.00e-97	349.00
IUUC-Tvi-122671	Trichoderma virens	31.80	2.00e-95	343.00
IUUC-Tae-125581	Triticum aestivum	33.63	5.00e-107	382.00
IUUC-Tur-126404	Triticum urartu	24.17	4.00e-23	103.00
IUUC-Tme-126971	Tuber melanosporum	34.31	2.00e-112	399.00
IUUC-Tbe-127858	Tupaia belangeri	77.28	0.00e+00	652.00
IUUC-Ttr-128173	Tursiops truncatus	93.75	0.00e+00	1532.00
IUUC-Uma-129322	Ustilago maydis	33.25	3.00e-105	376.00
IUUC-Vda-129682	Verticillium dahliae	32.21	7.00e-92	332.00
IUUC-Vpa-130607	Vicugna pacos	93.06	0.00e+00	1420.00
IUUC-Vvi-131153	Vitis vinifera	33.33	5.00e-112	398.00
IUUC-Xtr-132208	Xenopus tropicalis	75.22	0.00e+00	1239.00
IUUC-Xma-133098	Xiphophorus maculatus	68.74	0.00e+00	1138.00
IUUC-Yli-134646	Yarrowia lipolytica	38.93	2.00e-95	343.00
IUUC-Zma-135920	Zea mays	30.93	5.00e-92	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence