iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048484

Ensembl Protein ID

ENSSTOP00000012693.2

UniProt Accession

I3MME2; I3MME2_ICTTR

Genbank Protein ID

ENSSTOP00000012693

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01099234

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014156.2	ENSSTOT00000014168.2	ENSSTOP00000012693.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	79.49	0.00e+00	1834.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MQRKNCVRGQ SSPTMTSTGQ DSNTTRQRRS RHSPQSPLQD SSVTSKRSVK KGAVSRSSPN 60
LAEVKKKGKM KKLSQATEED LVVGLQGLDL NLQSKAQVGT GLVFDEQLNE FHCLWDDSFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTCGGAG GAGCGGGGCT TGTTGAAACG CTATAGGGGC GGGATCTGAT GCAGAGGAAG 60
GTACCCCGAT AAGGGGAGGA GTTAAATGAA TCGTTAAGGG TGGAGTCGAG GCCAGGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.61	1.00e-70	260.00
IUUC-Aml-002087	Ailuropoda melanoleuca	80.43	0.00e+00	1805.00
IUUC-Atr-002745	Amborella trichopoda	40.53	4.00e-86	311.00
IUUC-Aca-004303	Anolis carolinensis	49.17	0.00e+00	1108.00
IUUC-Aly-006432	Arabidopsis lyrata	44.23	1.00e-81	297.00
IUUC-Ath-007355	Arabidopsis thaliana	44.78	3.00e-87	315.00
IUUC-Ago-007972	Ashbya gossypii	43.09	2.00e-85	309.00
IUUC-Acl-008187	Aspergillus clavatus	45.53	3.00e-87	316.00
IUUC-Afl-008399	Aspergillus flavus	47.06	7.00e-49	187.00
IUUC-Afu-008954	Aspergillus fumigatus	40.86	9.00e-76	277.00
IUUC-Ani-009142	Aspergillus nidulans	42.48	8.00e-80	291.00
IUUC-Ang-009522	Aspergillus niger	34.74	2.00e-44	174.00
IUUC-Aor-010069	Aspergillus oryzae	42.53	4.00e-78	285.00
IUUC-Ate-010291	Aspergillus terreus	44.47	3.00e-87	315.00
IUUC-Ame-010780	Astyanax mexicanus	45.70	0.00e+00	912.00
IUUC-Bta-013052	Bos taurus	76.47	0.00e+00	1663.00
IUUC-Bci-013789	Botrytis cinerea	40.35	2.00e-79	290.00
IUUC-Bdi-014007	Brachypodium distachyon	44.00	7.00e-87	314.00
IUUC-Bol-015468	Brassica oleracea	43.72	8.00e-85	307.00
IUUC-Bra-016680	Brassica rapa	45.53	3.00e-85	309.00
IUUC-Cel-018220	Caenorhabditis elegans	37.89	2.00e-146	513.00
IUUC-Cja-019473	Callithrix jacchus	76.65	0.00e+00	1735.00
IUUC-Cfa-020263	Canis familiaris	80.86	0.00e+00	1770.00
IUUC-Cpo-021691	Cavia porcellus	83.23	0.00e+00	1850.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	55.51	4.00e-58	217.00
IUUC-Csa-024223	Chlorocebus sabaeus	79.26	0.00e+00	1800.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.31	2.00e-78	286.00
IUUC-Cne-026978	Cryptococcus neoformans	44.56	9.00e-91	327.00
IUUC-Dre-028820	Danio rerio	57.44	0.00e+00	922.00
IUUC-Dno-029160	Dasypus novemcinctus	71.26	0.00e+00	1561.00
IUUC-Dor-030859	Dipodomys ordii	73.40	0.00e+00	1685.00
IUUC-Dse-031186	Dothistroma septosporum	40.93	3.00e-79	289.00
IUUC-Dme-031963	Drosophila melanogaster	44.49	0.00e+00	675.00
IUUC-Ete-032279	Echinops telfairi	66.03	3.00e-154	538.00
IUUC-Eca-033842	Equus caballus	79.53	0.00e+00	1823.00
IUUC-Eeu-034487	Erinaceus europaeus	76.65	5.00e-152	531.00
IUUC-Fca-036430	Felis catus	79.88	0.00e+00	1759.00
IUUC-Fox-038067	Fusarium oxysporum	41.86	5.00e-81	295.00
IUUC-Fso-038263	Fusarium solani	41.60	9.00e-82	297.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.11	2.00e-74	273.00
IUUC-Gma-043738	Glycine max	46.54	6.00e-88	318.00
IUUC-Ggo-045022	Gorilla gorilla	78.84	0.00e+00	1804.00
IUUC-Hsa-046904	Homo sapiens	78.34	0.00e+00	1790.00
IUUC-Hvu-047285	Hordeum vulgare	46.01	6.00e-85	306.00
IUUC-Kpa-049281	Komagataella pastoris	41.64	4.00e-86	312.00
IUUC-Lch-050330	Latimeria chalumnae	46.60	0.00e+00	946.00
IUUC-Lpe-051214	Leersia perrieri	47.22	2.00e-87	316.00
IUUC-Lma-053263	Leptosphaeria maculans	43.32	8.00e-92	331.00
IUUC-Laf-053386	Loxodonta africana	76.37	0.00e+00	1699.00
IUUC-Mcc-055530	Macaca mulatta	79.51	0.00e+00	1789.00
IUUC-Meu-056442	Macropus eugenii	68.41	0.00e+00	984.00
IUUC-Mor-057095	Magnaporthe oryzae	40.30	4.00e-85	308.00
IUUC-Mpo-057389	Magnaporthe poae	42.52	3.00e-74	273.00
IUUC-Mtr-058463	Medicago truncatula	44.57	1.00e-89	323.00
IUUC-Mla-059143	Melampsora laricipopulina	44.57	2.00e-85	310.00
IUUC-Mmr-060637	Microcebus murinus	80.61	0.00e+00	1877.00
IUUC-Mdo-062198	Monodelphis domestica	68.14	0.00e+00	1080.00
IUUC-Mmu-063346	Mus musculus	78.97	0.00e+00	1785.00
IUUC-Mac-064630	Musa acuminata	46.18	3.00e-84	305.00
IUUC-Mpu-065884	Mustela putorius furo	79.83	0.00e+00	1817.00
IUUC-Mlu-068117	Myotis lucifugus	79.30	0.00e+00	1758.00
IUUC-Nfi-068404	Neosartorya fischeri	44.74	2.00e-86	313.00
IUUC-Ncr-068672	Neurospora crassa	41.27	3.00e-81	296.00
IUUC-Nle-069868	Nomascus leucogenys	92.71	0.00e+00	749.00
IUUC-Opr-071074	Ochotona princeps	67.56	0.00e+00	1070.00
IUUC-Ont-072246	Oreochromis niloticus	46.11	0.00e+00	927.00
IUUC-Oan-072911	Ornithorhynchus anatinus	69.60	7.00e-109	388.00
IUUC-Ocu-074627	Oryctolagus cuniculus	80.36	0.00e+00	1880.00
IUUC-Oba-075489	Oryza barthii	46.63	7.00e-86	311.00
IUUC-Obr-076150	Oryza brachyantha	47.09	7.00e-87	314.00
IUUC-Ogl-077437	Oryza glaberrima	46.63	5.00e-86	311.00
IUUC-Ogu-078370	Oryza glumaepatula	46.93	6.00e-87	315.00
IUUC-Oin-079210	Oryza indica	46.93	7.00e-87	314.00
IUUC-Olo-080971	Oryza longistaminata	47.14	4.00e-74	271.00
IUUC-Oni-082031	Oryza nivara	44.10	1.00e-86	313.00
IUUC-Opu-083471	Oryza punctata	38.50	4.00e-86	312.00
IUUC-Oru-084755	Oryza rufipogon	46.93	6.00e-87	315.00
IUUC-Osa-085447	Oryza sativa	46.93	7.00e-87	314.00
IUUC-Oga-089155	Otolemur garnettii	79.19	0.00e+00	1804.00
IUUC-Oar-089620	Ovis aries	76.72	0.00e+00	1685.00
IUUC-Ptr-090812	Pan troglodytes	89.62	0.00e+00	1283.00
IUUC-Pan-092340	Papio anubis	79.26	0.00e+00	1788.00
IUUC-Pma-094386	Petromyzon marinus	53.11	0.00e+00	806.00
IUUC-Pno-095131	Phaeosphaeria nodorum	46.80	7.00e-79	287.00
IUUC-Ppa-095550	Physcomitrella patens	45.18	1.00e-87	317.00
IUUC-Pfo-096110	Poecilia formosa	48.07	0.00e+00	852.00
IUUC-Pab-098422	Pongo abelii	78.09	0.00e+00	1751.00
IUUC-Pop-099174	Populus trichocarpa	41.62	1.00e-80	294.00
IUUC-Pca-100833	Procavia capensis	74.12	0.00e+00	1546.00
IUUC-Ppe-101644	Prunus persica	44.29	4.00e-89	322.00
IUUC-Pva-102410	Pteropus vampyrus	76.69	0.00e+00	1296.00
IUUC-Ptt-103841	Puccinia triticina	40.05	1.00e-84	307.00
IUUC-Pte-104383	Pyrenophora teres	43.26	3.00e-88	319.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.52	1.00e-88	320.00
IUUC-Rno-105131	Rattus norvegicus	77.53	0.00e+00	1777.00
IUUC-Sce-106274	Saccharomyces cerevisiae	42.29	6.00e-83	301.00
IUUC-Sha-106661	Sarcophilus harrisii	56.07	0.00e+00	820.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	43.09	1.00e-89	323.00
IUUC-Spo-108300	Schizosaccharomyces pombe	47.81	2.00e-92	333.00
IUUC-Smo-109615	Selaginella moellendorffii	48.94	1.00e-86	313.00
IUUC-Sit-110160	Setaria italica	43.17	2.00e-82	300.00
IUUC-Sly-111164	Solanum lycopersicum	39.55	2.00e-82	299.00
IUUC-Stu-112685	Solanum tuberosum	41.47	8.00e-74	271.00
IUUC-Sar-113692	Sorex araneus	67.33	0.00e+00	768.00
IUUC-Sbi-114301	Sorghum bicolor	45.87	8.00e-81	294.00
IUUC-Sre-115013	Sporisorium reilianum	44.47	2.00e-84	306.00
IUUC-Ssc-115724	Sus scrofa	78.26	0.00e+00	1654.00
IUUC-Tgu-116605	Taeniopygia guttata	47.72	0.00e+00	678.00
IUUC-Tru-117614	Takifugu rubripes	46.90	0.00e+00	949.00
IUUC-Tsy-118807	Tarsius syrichta	67.97	0.00e+00	859.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.62	0.00e+00	793.00
IUUC-Tca-121312	Theobroma cacao	46.11	3.00e-85	308.00
IUUC-Tre-121930	Trichoderma reesei	40.93	3.00e-82	299.00
IUUC-Tvi-122373	Trichoderma virens	40.86	9.00e-83	301.00
IUUC-Tae-123064	Triticum aestivum	41.14	8.00e-79	286.00
IUUC-Tme-127027	Tuber melanosporum	42.51	1.00e-72	266.00
IUUC-Tbe-127675	Tupaia belangeri	50.92	2.00e-84	306.00
IUUC-Ttr-128411	Tursiops truncatus	77.56	0.00e+00	1757.00
IUUC-Uma-129408	Ustilago maydis	42.40	2.00e-77	283.00
IUUC-Vda-129994	Verticillium dahliae	37.97	2.00e-76	280.00
IUUC-Vpa-130525	Vicugna pacos	82.45	8.00e-62	231.00
IUUC-Vvi-131038	Vitis vinifera	42.02	2.00e-86	313.00
IUUC-Xtr-132618	Xenopus tropicalis	58.18	0.00e+00	951.00
IUUC-Xma-133730	Xiphophorus maculatus	49.75	0.00e+00	716.00
IUUC-Yli-134680	Yarrowia lipolytica	43.33	2.00e-88	319.00
IUUC-Zma-135110	Zea mays	42.78	2.00e-82	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence