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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-104890
UUCD1 version UUC-RaN-00842
Ensembl Protein ID ENSRNOP00000074435.1
UniProt Accession Q5M9G8; DCA11_RAT
Genbank Protein ID AAH87110.1; AAH91364.1
Protein Name DDB1- and CUL4-associated factor 11; WD repeat-containing protein 23
Genbank Nucleotide ID BC087110; BC091364
Gene Name Dcaf11; Wdr23
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000018825.6 ENSRNOT00000077584.1 ENSRNOP00000074435.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.50e-25 88.5 482 514
UBD/Beta-Prp 5.60e-47 160.7 270 516
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           H++ v+++++   +  +vs+s+Dg++++W +r+
   Q: 482  HKACVRDVSWhpFEEKIVSSSWDGSLRLWQYRQ 514
           9999******965599*************9775 PP
   

   UBD/Beta-Prp
   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.....tgkcvhtlkghedsv 97
           ++++s d++ ++ g  dg++ v+d ++     ++++he+ v+av f + ++ il +g++D++ kvwd +     ++k+v +l gh+d +
   Q: 270  SIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSqILFSGGDDAICKVWDRRtmredDPKPVGALAGHQDGI 358
           47788899999999999999999999999999999999999999997755449999999999999977777777999999999999999 PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.....................................tlsghdgvvncvv..... 144
           + +++  +  +l+s s+d+ti++wd++  +  e                                      t +gh  + + ++     
   Q: 359  TFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGmeasrlaatqqnwdyrwqqvpkkawkklklpgdsslmTYRGHGVLHTLIRcrfsp 447
           99999999999999999999999999988888778889999999999999999999999999999999999777776555554422233 PP
   S: 145  vhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
            h++g + + sG+  ++v ++dl +g ++++lt  h+  v+ +s+++  + +vs s dg+++lw++++ e
   Q: 448  AHSTGqQFIYSGCSTGKVVVYDLLSGHIVKKLTN-HKACVRDVSWHPFEEKIVSSSWDGSLRLWQYRQAE 516
           5788888999999999999999999999999987.99999999999999999999999999999998655 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
 May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Sequence
(Fasta)
MGSRNSSSAG SGSLEPSEGL SRRGAGLRRS EEEEEEDEDV DLAQVLAYLL RRGQVRLVQG 60
GGAANLQLIQ ALSDSEEEHD SAWDGRLGDR YNPPVDATPD TRELEYNEIK TRVELATGRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-104890|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCAGCCAAT TCCAGTCCGC TACGACTTAA CGCCCCCCCT TGGGTTAAGA AATTTCTCCA 60
GCCCACCCAT CAATCACCGG TCTCAGCTGT CCAATCAGCG GACCAAGGGG GCGGAACATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-104890|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR017399--DCAF11/LEC14B
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0016567--P:protein ubiquitination
KEGG rno:305895
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000659 Aegilops tauschii 41.64 9.00e-65 240.00
IUUC-Aml-001732 Ailuropoda melanoleuca 92.71 0.00e+00 985.00
IUUC-Atr-002856 Amborella trichopoda 40.58 7.00e-80 290.00
IUUC-Aca-005081 Anolis carolinensis 82.19 0.00e+00 839.00
IUUC-Aly-006571 Arabidopsis lyrata 43.42 7.00e-90 324.00
IUUC-Ath-007313 Arabidopsis thaliana 43.92 1.00e-90 327.00
IUUC-Acl-008126 Aspergillus clavatus 35.83 7.00e-59 221.00
IUUC-Afl-008513 Aspergillus flavus 34.88 1.00e-60 228.00
IUUC-Afu-008765 Aspergillus fumigatus 34.76 2.00e-57 217.00
IUUC-Ani-009456 Aspergillus nidulans 36.80 1.00e-63 237.00
IUUC-Ang-009781 Aspergillus niger 33.16 1.00e-52 201.00
IUUC-Aor-010093 Aspergillus oryzae 34.88 1.00e-60 228.00
IUUC-Ate-010456 Aspergillus terreus 35.45 4.00e-61 229.00
IUUC-Ame-011825 Astyanax mexicanus 70.62 1.00e-176 612.00
IUUC-Bgr-012310 Blumeria graminis 32.65 2.00e-57 216.00
IUUC-Bta-013043 Bos taurus 93.44 0.00e+00 974.00
IUUC-Bci-013758 Botrytis cinerea 35.84 5.00e-59 222.00
IUUC-Bdi-014294 Brachypodium distachyon 43.61 5.00e-87 314.00
IUUC-Bol-016065 Brassica oleracea 41.72 6.00e-88 318.00
IUUC-Bra-018035 Brassica rapa 44.05 9.00e-85 307.00
IUUC-Cel-018145 Caenorhabditis elegans 42.59 9.00e-87 314.00
IUUC-Cja-018940 Callithrix jacchus 93.49 0.00e+00 956.00
IUUC-Cfa-020064 Canis familiaris 96.17 0.00e+00 986.00
IUUC-Cpo-022220 Cavia porcellus 92.64 0.00e+00 967.00
IUUC-Cre-022728 Chlamydomonas reinhardtii 50.00 9.00e-65 239.00
IUUC-Csa-023158 Chlorocebus sabaeus 93.89 0.00e+00 954.00
IUUC-Cho-024797 Choloepus hoffmanni 75.83 1.00e-94 340.00
IUUC-Cgl-026444 Colletotrichum gloeosporioides 36.54 2.00e-62 233.00
IUUC-Cne-026917 Cryptococcus neoformans 36.44 1.00e-49 191.00
IUUC-Cme-027273 Cyanidioschyzon merolae 29.19 2.00e-44 174.00
IUUC-Dre-028711 Danio rerio 67.50 0.00e+00 729.00
IUUC-Dno-029851 Dasypus novemcinctus 93.40 0.00e+00 948.00
IUUC-Dor-030952 Dipodomys ordii 86.16 0.00e+00 823.00
IUUC-Dse-031288 Dothistroma septosporum 32.17 7.00e-57 215.00
IUUC-Dme-031925 Drosophila melanogaster 36.64 2.00e-80 293.00
IUUC-Ete-032983 Echinops telfairi 87.66 0.00e+00 849.00
IUUC-Eca-033499 Equus caballus 94.72 0.00e+00 1017.00
IUUC-Eeu-035179 Erinaceus europaeus 90.34 0.00e+00 770.00
IUUC-Fca-035615 Felis catus 96.36 0.00e+00 972.00
IUUC-Fox-037867 Fusarium oxysporum 37.64 3.00e-57 216.00
IUUC-Fso-038274 Fusarium solani 36.39 9.00e-58 218.00
IUUC-Gmo-038731 Gadus morhua 69.02 0.00e+00 721.00
IUUC-Ggr-039861 Gaeumannomyces graminis 33.69 8.00e-58 218.00
IUUC-Gac-041615 Gasterosteus aculeatus 70.19 0.00e+00 725.00
IUUC-Gma-043167 Glycine max 40.94 2.00e-89 323.00
IUUC-Hsa-046061 Homo sapiens 93.96 0.00e+00 979.00
IUUC-Hvu-047177 Hordeum vulgare 56.16 8.00e-62 229.00
IUUC-Itr-048985 Ictidomys tridecemlineatus 93.49 0.00e+00 951.00
IUUC-Lch-050257 Latimeria chalumnae 55.33 2.00e-156 546.00
IUUC-Lpe-051521 Leersia perrieri 44.23 1.00e-84 306.00
IUUC-Lma-053067 Leptosphaeria maculans 35.73 3.00e-53 203.00
IUUC-Laf-054259 Loxodonta africana 96.06 0.00e+00 957.00
IUUC-Mcc-054958 Macaca mulatta 94.11 0.00e+00 932.00
IUUC-Meu-056889 Macropus eugenii 85.62 0.00e+00 870.00
IUUC-Mor-057196 Magnaporthe oryzae 35.75 4.00e-57 216.00
IUUC-Mpo-057340 Magnaporthe poae 31.16 1.00e-54 207.00
IUUC-Mtr-058464 Medicago truncatula 42.72 1.00e-89 323.00
IUUC-Mla-058873 Melampsora laricipopulina 29.75 8.00e-50 191.00
IUUC-Mvi-060439 Microbotryum violaceum 34.38 1.00e-63 238.00
IUUC-Mmr-061329 Microcebus murinus 91.44 0.00e+00 953.00
IUUC-Mdo-062123 Monodelphis domestica 81.96 0.00e+00 854.00
IUUC-Mmu-063616 Mus musculus 97.24 0.00e+00 997.00
IUUC-Mac-064473 Musa acuminata 42.04 2.00e-81 296.00
IUUC-Mpu-066351 Mustela putorius furo 95.52 0.00e+00 870.00
IUUC-Mlu-067043 Myotis lucifugus 96.07 0.00e+00 941.00
IUUC-Nfi-068552 Neosartorya fischeri 34.76 3.00e-57 216.00
IUUC-Ncr-068715 Neurospora crassa 36.68 5.00e-57 216.00
IUUC-Nle-070052 Nomascus leucogenys 93.95 0.00e+00 973.00
IUUC-Opr-070605 Ochotona princeps 82.80 0.00e+00 879.00
IUUC-Ont-072411 Oreochromis niloticus 70.80 0.00e+00 712.00
IUUC-Ocu-074078 Oryctolagus cuniculus 95.50 0.00e+00 939.00
IUUC-Oba-075609 Oryza barthii 39.86 2.00e-86 313.00
IUUC-Obr-076556 Oryza brachyantha 43.54 3.00e-83 302.00
IUUC-Ogl-077467 Oryza glaberrima 39.86 1.00e-85 310.00
IUUC-Ogu-078264 Oryza glumaepatula 40.68 6.00e-80 291.00
IUUC-Oin-079588 Oryza indica 39.86 2.00e-86 312.00
IUUC-Olo-080362 Oryza longistaminata 39.47 5.00e-73 268.00
IUUC-Ome-081874 Oryza meridionalis 40.66 2.00e-86 313.00
IUUC-Oni-082655 Oryza nivara 39.86 2.00e-86 313.00
IUUC-Opu-084069 Oryza punctata 41.48 2.00e-85 309.00
IUUC-Oru-085209 Oryza rufipogon 39.86 2.00e-86 313.00
IUUC-Osa-086287 Oryza sativa 39.64 2.00e-85 309.00
IUUC-Ola-086329 Oryzias latipes 69.77 0.00e+00 724.00
IUUC-Oga-088779 Otolemur garnettii 94.08 0.00e+00 960.00
IUUC-Oar-089262 Ovis aries 93.44 0.00e+00 974.00
IUUC-Ptr-091346 Pan troglodytes 89.25 0.00e+00 947.00
IUUC-Pan-092716 Papio anubis 94.28 0.00e+00 959.00
IUUC-Pma-094148 Petromyzon marinus 72.32 9.00e-127 446.00
IUUC-Pno-095116 Phaeosphaeria nodorum 35.22 1.00e-52 201.00
IUUC-Ppa-095260 Physcomitrella patens 44.30 2.00e-91 330.00
IUUC-Pfo-096424 Poecilia formosa 68.65 0.00e+00 720.00
IUUC-Pab-098091 Pongo abelii 89.43 0.00e+00 916.00
IUUC-Pop-099095 Populus trichocarpa 42.60 4.00e-87 315.00
IUUC-Pca-100153 Procavia capensis 95.26 0.00e+00 940.00
IUUC-Ppe-102075 Prunus persica 42.61 4.00e-88 318.00
IUUC-Pva-102598 Pteropus vampyrus 91.26 0.00e+00 969.00
IUUC-Pgr-103327 Puccinia graminis 33.60 1.00e-52 201.00
IUUC-Ptt-103861 Puccinia triticina 26.35 2.00e-27 116.00
IUUC-Pte-104286 Pyrenophora teres 35.39 9.00e-62 231.00
IUUC-Pyt-104745 Pyrenophora triticirepentis 38.31 2.00e-52 200.00
IUUC-Sha-106540 Sarcophilus harrisii 84.84 0.00e+00 867.00
IUUC-Ssl-108528 Sclerotinia sclerotiorum 32.59 2.00e-48 187.00
IUUC-Smo-109019 Selaginella moellendorffii 40.39 4.00e-83 301.00
IUUC-Sit-110726 Setaria italica 43.40 1.00e-88 320.00
IUUC-Sly-110856 Solanum lycopersicum 41.57 5.00e-92 331.00
IUUC-Stu-112589 Solanum tuberosum 41.09 8.00e-82 297.00
IUUC-Sar-113742 Sorex araneus 94.50 0.00e+00 948.00
IUUC-Sbi-114505 Sorghum bicolor 44.05 3.00e-70 258.00
IUUC-Sre-115073 Sporisorium reilianum 37.64 9.00e-55 208.00
IUUC-Ssc-116019 Sus scrofa 91.26 0.00e+00 967.00
IUUC-Tru-118536 Takifugu rubripes 67.75 0.00e+00 723.00
IUUC-Tsy-119518 Tarsius syrichta 93.56 0.00e+00 968.00
IUUC-Tni-120264 Tetraodon nigroviridis 69.56 0.00e+00 711.00
IUUC-Tca-121212 Theobroma cacao 41.44 7.00e-84 304.00
IUUC-Tre-122144 Trichoderma reesei 35.90 4.00e-57 215.00
IUUC-Tvi-122472 Trichoderma virens 36.07 5.00e-59 222.00
IUUC-Tae-124083 Triticum aestivum 45.82 2.00e-83 303.00
IUUC-Tur-126714 Triticum urartu 39.25 3.00e-73 269.00
IUUC-Tme-127050 Tuber melanosporum 34.73 2.00e-68 253.00
IUUC-Tbe-127495 Tupaia belangeri 95.46 0.00e+00 968.00
IUUC-Ttr-128553 Tursiops truncatus 93.99 0.00e+00 994.00
IUUC-Uma-129557 Ustilago maydis 37.92 5.00e-55 209.00
IUUC-Vda-129951 Verticillium dahliae 34.84 3.00e-60 226.00
IUUC-Vpa-130542 Vicugna pacos 84.45 2.00e-103 369.00
IUUC-Vvi-131266 Vitis vinifera 43.37 6.00e-89 321.00
IUUC-Xtr-132525 Xenopus tropicalis 71.26 0.00e+00 719.00
IUUC-Xma-133165 Xiphophorus maculatus 69.03 0.00e+00 726.00
IUUC-Yli-134635 Yarrowia lipolytica 25.88 2.00e-20 94.40
IUUC-Zma-135874 Zea mays 41.01 4.00e-86 311.00
Created Date 25-Jun-2017

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