iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115500

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

FP017286

Gene Name

USP51

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012349.2	ENSSSCT00000013504.1	ENSSSCP00000013143.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-88	297.7	363	705

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L++ip l++++l+ +k+k+  +   +p+ +l++++ +lf+++++++++   p +ll+ ++  ae++ gy+qq
   Q: 363  GLINLGNTCFMNCIVQALTHIPLLKDFFLS-DKHKCIMT---SPSLCLVCEMSSLFHAMYSGNRTPHIPYKLLHLIWIHAEHLAGYRQQ 447
           9*****************************.99999875...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl  +ld l+++ k+       +         s  +e ++++  +++i+++F g l+s+++c+ c++vs++ +p +d+sl++pg+
   Q: 448  DAHEFLIAILDVLHRHSKE-------D---------SVGQEASNPNCCNCIIDHIFTGGLQSDVTCQVCHTVSTTIDPCWDISLDLPGS 520
           *****************33.......2.........233457899******************************************99 PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
             t                       sl+dcL+ ft++e+l ++ k++c++c+++qe++k+l++kklP v ++h+kRf  ++ +k+r+k
   Q: 521  CATFSCqnperadgtvsrderipgnpSLTDCLQWFTRREHLGSSAKIKCSSCQSYQESTKQLTMKKLPIVACFHIKRF--EHVGKQRRK 607
           9764448999********************************************************************..88889**** PP
   S: 249  inkkvefpleLdlspfctspeekqke...........kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleet 326
           in+ ++fpleLd++pf++s++e++ +           ++kY+L+av++H+G+l+sGHY+++++++k++W+ +dD  +t+ + e+ l   
   Q: 608  INTFISFPLELDMTPFLSSTKESKMKerqpqtdyapiENKYSLFAVINHHGTLESGHYTSFIRQQKDQWFSCDDAVITKATIEDLLY-- 694
           *****************9977766668999*********************************************************.. PP
   S: 327  gstaYvlfYkrr 338
            s++Y+lfY+++
   Q: 695  -SEGYLLFYHKQ 705
           .********985 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAQVREASLP LGSLVRCSSG DGRGASPEEG AEKAGEMEEE ELGAAKAYSG PGAVEMKLEP 60
SQEHKPAPEE NFTWSGSCSD EKVLPSNPLR CYSSSLTLCP RRKPRPRPQP GTHFLGPPRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCGCCTA GATAGCAGCA GCTGCTGACG TTTTGTATCT TGCGTCTGGG GGCTAAGGTT 60
ACTCAGACCT TTTAACAAAC CACGGGGCTG GGATCCTTGC AGACATGCGG ATGAGAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033383--USP51
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:2001020--P:regulation of response to DNA damage stimulus
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100519179

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001480	Ailuropoda melanoleuca	90.33	0.00e+00	964.00
IUUC-Ang-009694	Aspergillus niger	28.33	9.00e-55	207.00
IUUC-Aor-010035	Aspergillus oryzae	34.59	1.00e-36	146.00
IUUC-Ate-010382	Aspergillus terreus	31.70	3.00e-50	192.00
IUUC-Bol-016509	Brassica oleracea	38.56	3.00e-74	272.00
IUUC-Bra-016962	Brassica rapa	36.73	1.00e-72	267.00
IUUC-Cja-019402	Callithrix jacchus	89.26	0.00e+00	696.00
IUUC-Csa-023824	Chlorocebus sabaeus	91.67	0.00e+00	967.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	29.49	1.00e-54	207.00
IUUC-Dse-031415	Dothistroma septosporum	29.14	2.00e-58	219.00
IUUC-Eca-033872	Equus caballus	91.49	0.00e+00	970.00
IUUC-Fca-035534	Felis catus	90.94	0.00e+00	983.00
IUUC-Ggo-045109	Gorilla gorilla	90.23	0.00e+00	941.00
IUUC-Hsa-045765	Homo sapiens	91.49	0.00e+00	980.00
IUUC-Itr-048281	Ictidomys tridecemlineatus	92.25	0.00e+00	926.00
IUUC-Mcc-055420	Macaca mulatta	91.22	0.00e+00	998.00
IUUC-Mla-059185	Melampsora laricipopulina	33.15	3.00e-42	165.00
IUUC-Mmr-061690	Microcebus murinus	90.64	0.00e+00	983.00
IUUC-Mmu-063435	Mus musculus	80.08	0.00e+00	818.00
IUUC-Mac-065419	Musa acuminata	34.41	1.00e-75	276.00
IUUC-Mpu-065679	Mustela putorius furo	90.79	0.00e+00	951.00
IUUC-Mlu-067084	Myotis lucifugus	90.22	0.00e+00	977.00
IUUC-Nle-069859	Nomascus leucogenys	91.86	0.00e+00	975.00
IUUC-Ocu-074365	Oryctolagus cuniculus	90.96	0.00e+00	943.00
IUUC-Ptr-091479	Pan troglodytes	91.30	0.00e+00	982.00
IUUC-Pan-091707	Papio anubis	91.67	0.00e+00	966.00
IUUC-Pab-097894	Pongo abelii	92.28	0.00e+00	986.00
IUUC-Pop-099893	Populus trichocarpa	37.99	6.00e-85	308.00
IUUC-Pgr-103657	Puccinia graminis	29.90	4.00e-39	155.00
IUUC-Pte-104340	Pyrenophora teres	31.78	9.00e-56	210.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	34.74	1.00e-63	236.00
IUUC-Rno-105644	Rattus norvegicus	79.64	0.00e+00	833.00
IUUC-Sce-106247	Saccharomyces cerevisiae	30.11	5.00e-50	191.00
IUUC-Sar-113426	Sorex araneus	78.93	0.00e+00	809.00
IUUC-Tsy-119413	Tarsius syrichta	89.49	0.00e+00	962.00
IUUC-Tca-121154	Theobroma cacao	40.66	2.00e-92	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence