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Tag Content
iUUCD ID IUUC-Mcc-055574
Ensembl Protein ID ENSMMUP00000042986.1
UniProt Accession A0A1D5Q4M2; A0A1D5Q4M2_MACMU
Genbank Protein ID ENSMMUP00000042986
Protein Name DNA repair protein REV1
Genbank Nucleotide ID JSUE03011577
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000015515.3 ENSMMUT00000021764.3 ENSMMUP00000020360.3
ENSMMUG00000015515.3 ENSMMUT00000055894.1 ENSMMUP00000042986.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 2.30e-21 75.8 1010 1038
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1010 AFSQVDPEVFAALPAELQRELKAAYDQRQ 1038
           59*************************98 PP
   
Organism Macaca mulatta
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRKRA ENDGWEKWGG YMAAKVQKLE EQFRSDAALQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055574|UBD,UBM|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTGAAAGAC AGTAATTGGC TGCCCTGTTA ATGTGACTGG ATAAGGAGAG ATTGGCAGGT 60
TATTTTAGGT TGTGAATCAC AGTTTCAGAA ACCGTTATCA CGTTCCTCAA GGTCATCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055574|UBD,UBM|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0016779--F:nucleotidyltransferase activity
GO:0042276--P:error-prone translesion synthesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 30.69 2.00e-31 131.00
IUUC-Aml-001185 Ailuropoda melanoleuca 88.76 0.00e+00 2152.00
IUUC-Atr-002915 Amborella trichopoda 30.41 5.00e-107 382.00
IUUC-Apl-004054 Anas platyrhynchos 75.79 0.00e+00 1781.00
IUUC-Aca-004304 Anolis carolinensis 68.63 0.00e+00 1632.00
IUUC-Aly-005696 Arabidopsis lyrata 36.42 4.00e-86 313.00
IUUC-Ath-006893 Arabidopsis thaliana 36.31 9.00e-87 315.00
IUUC-Ago-007722 Ashbya gossypii 27.72 2.00e-38 154.00
IUUC-Acl-008347 Aspergillus clavatus 34.75 1.00e-88 322.00
IUUC-Afl-008444 Aspergillus flavus 35.92 2.00e-88 320.00
IUUC-Afu-008837 Aspergillus fumigatus 31.68 1.00e-86 315.00
IUUC-Ani-009188 Aspergillus nidulans 38.91 1.00e-92 335.00
IUUC-Ang-009866 Aspergillus niger 33.85 2.00e-98 354.00
IUUC-Aor-010107 Aspergillus oryzae 35.92 3.00e-88 320.00
IUUC-Ate-010359 Aspergillus terreus 32.13 6.00e-93 336.00
IUUC-Ame-010664 Astyanax mexicanus 49.37 0.00e+00 1098.00
IUUC-Bgr-012244 Blumeria graminis 31.63 4.00e-83 303.00
IUUC-Bta-013405 Bos taurus 80.55 0.00e+00 1807.00
IUUC-Bci-013849 Botrytis cinerea 31.54 1.00e-88 321.00
IUUC-Bdi-014066 Brachypodium distachyon 36.52 3.00e-84 306.00
IUUC-Bol-015544 Brassica oleracea 37.08 5.00e-89 322.00
IUUC-Bra-017792 Brassica rapa 35.02 1.00e-84 308.00
IUUC-Cel-018148 Caenorhabditis elegans 36.16 3.00e-82 300.00
IUUC-Cja-019742 Callithrix jacchus 81.87 0.00e+00 1600.00
IUUC-Cfa-020112 Canis familiaris 89.31 0.00e+00 2182.00
IUUC-Cpo-022152 Cavia porcellus 84.84 0.00e+00 2112.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 42.15 2.00e-40 160.00
IUUC-Csa-023504 Chlorocebus sabaeus 98.48 0.00e+00 2419.00
IUUC-Cho-024780 Choloepus hoffmanni 65.95 0.00e+00 725.00
IUUC-Cin-025276 Ciona intestinalis 42.47 5.00e-112 398.00
IUUC-Csv-026283 Ciona savignyi 45.19 1.00e-114 407.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 28.51 1.00e-90 328.00
IUUC-Cne-027079 Cryptococcus neoformans 34.12 2.00e-77 285.00
IUUC-Cme-027346 Cyanidioschyzon merolae 28.76 2.00e-47 184.00
IUUC-Dre-028073 Danio rerio 50.79 0.00e+00 1097.00
IUUC-Dno-030038 Dasypus novemcinctus 81.82 0.00e+00 2006.00
IUUC-Dor-031100 Dipodomys ordii 84.57 0.00e+00 1511.00
IUUC-Dse-031310 Dothistroma septosporum 31.18 8.00e-86 312.00
IUUC-Dme-031991 Drosophila melanogaster 42.94 5.00e-113 402.00
IUUC-Ete-033082 Echinops telfairi 76.92 0.00e+00 1404.00
IUUC-Eca-033471 Equus caballus 88.20 0.00e+00 2147.00
IUUC-Eeu-034993 Erinaceus europaeus 84.98 0.00e+00 1415.00
IUUC-Fca-035367 Felis catus 88.55 0.00e+00 2076.00
IUUC-Fal-036973 Ficedula albicollis 75.30 0.00e+00 1726.00
IUUC-Fox-037677 Fusarium oxysporum 31.06 2.00e-88 320.00
IUUC-Fso-038252 Fusarium solani 30.87 2.00e-90 327.00
IUUC-Gmo-039669 Gadus morhua 52.57 0.00e+00 821.00
IUUC-Ggr-039988 Gaeumannomyces graminis 32.15 1.00e-85 311.00
IUUC-Gga-040423 Gallus gallus 75.63 0.00e+00 1777.00
IUUC-Gac-042134 Gasterosteus aculeatus 47.78 0.00e+00 973.00
IUUC-Gma-042929 Glycine max 32.49 5.00e-114 405.00
IUUC-Ggo-044528 Gorilla gorilla 97.92 0.00e+00 2378.00
IUUC-Hsa-046259 Homo sapiens 97.84 0.00e+00 2346.00
IUUC-Hvu-047139 Hordeum vulgare 37.16 2.00e-58 220.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 89.23 0.00e+00 2174.00
IUUC-Kpa-049169 Komagataella pastoris 28.88 1.00e-60 228.00
IUUC-Lch-050471 Latimeria chalumnae 65.78 0.00e+00 1535.00
IUUC-Lpe-050800 Leersia perrieri 33.54 1.00e-87 318.00
IUUC-Loc-052320 Lepisosteus oculatus 46.85 0.00e+00 933.00
IUUC-Lma-053149 Leptosphaeria maculans 30.14 2.00e-85 311.00
IUUC-Laf-053810 Loxodonta africana 82.70 0.00e+00 1954.00
IUUC-Meu-055945 Macropus eugenii 65.93 0.00e+00 1139.00
IUUC-Mor-057195 Magnaporthe oryzae 29.95 2.00e-91 331.00
IUUC-Mpo-057488 Magnaporthe poae 34.86 5.00e-86 313.00
IUUC-Mtr-057955 Medicago truncatula 36.55 2.00e-88 320.00
IUUC-Mla-059027 Melampsora laricipopulina 36.24 2.00e-81 297.00
IUUC-Mga-060156 Meleagris gallopavo 75.24 0.00e+00 1771.00
IUUC-Mvi-060398 Microbotryum violaceum 36.21 8.00e-82 299.00
IUUC-Mmr-061113 Microcebus murinus 91.47 0.00e+00 2183.00
IUUC-Mdo-063001 Monodelphis domestica 82.92 0.00e+00 1974.00
IUUC-Mmu-063180 Mus musculus 82.46 0.00e+00 2012.00
IUUC-Mac-065551 Musa acuminata 38.75 8.00e-55 208.00
IUUC-Mpu-066525 Mustela putorius furo 89.00 0.00e+00 2139.00
IUUC-Mlu-067877 Myotis lucifugus 86.12 0.00e+00 2074.00
IUUC-Nfi-068418 Neosartorya fischeri 32.29 4.00e-87 316.00
IUUC-Ncr-068648 Neurospora crassa 32.34 4.00e-89 323.00
IUUC-Nle-069959 Nomascus leucogenys 97.84 0.00e+00 2338.00
IUUC-Opr-070522 Ochotona princeps 83.01 0.00e+00 1187.00
IUUC-Ont-072293 Oreochromis niloticus 49.59 0.00e+00 792.00
IUUC-Oan-073519 Ornithorhynchus anatinus 78.94 0.00e+00 1885.00
IUUC-Ocu-074492 Oryctolagus cuniculus 85.38 0.00e+00 1927.00
IUUC-Oba-075567 Oryza barthii 31.99 6.00e-89 322.00
IUUC-Obr-076332 Oryza brachyantha 36.49 6.00e-86 312.00
IUUC-Ogl-077348 Oryza glaberrima 31.99 7.00e-89 322.00
IUUC-Ogu-078779 Oryza glumaepatula 31.83 2.00e-88 320.00
IUUC-Oin-079738 Oryza indica 29.48 1.00e-76 281.00
IUUC-Olo-080701 Oryza longistaminata 29.55 7.00e-77 282.00
IUUC-Ome-081708 Oryza meridionalis 36.53 8.00e-85 309.00
IUUC-Oni-082251 Oryza nivara 31.65 6.00e-86 312.00
IUUC-Opu-083528 Oryza punctata 31.26 5.00e-80 293.00
IUUC-Oru-084293 Oryza rufipogon 31.21 2.00e-83 304.00
IUUC-Osa-085549 Oryza sativa 31.99 2.00e-88 321.00
IUUC-Ola-086793 Oryzias latipes 46.10 0.00e+00 1002.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.68 2.00e-59 223.00
IUUC-Oga-089006 Otolemur garnettii 90.23 0.00e+00 2167.00
IUUC-Oar-089597 Ovis aries 81.82 0.00e+00 1972.00
IUUC-Ptr-091520 Pan troglodytes 97.92 0.00e+00 2347.00
IUUC-Pan-092333 Papio anubis 99.44 0.00e+00 2352.00
IUUC-Psi-094004 Pelodiscus sinensis 77.54 0.00e+00 1842.00
IUUC-Pma-094128 Petromyzon marinus 53.23 8.00e-94 337.00
IUUC-Pno-094849 Phaeosphaeria nodorum 28.77 1.00e-77 285.00
IUUC-Ppa-095714 Physcomitrella patens 27.70 1.00e-95 344.00
IUUC-Pfo-096569 Poecilia formosa 47.68 0.00e+00 986.00
IUUC-Pab-097960 Pongo abelii 97.60 0.00e+00 2341.00
IUUC-Pop-098921 Populus trichocarpa 32.24 2.00e-82 301.00
IUUC-Pca-100509 Procavia capensis 69.01 0.00e+00 1186.00
IUUC-Ppe-101730 Prunus persica 33.82 6.00e-118 419.00
IUUC-Pva-102142 Pteropus vampyrus 85.49 0.00e+00 2045.00
IUUC-Pgr-103446 Puccinia graminis 31.05 2.00e-70 261.00
IUUC-Ptt-103849 Puccinia triticina 30.06 2.00e-73 272.00
IUUC-Pte-104128 Pyrenophora teres 30.03 2.00e-84 307.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 31.67 2.00e-81 297.00
IUUC-Rno-104871 Rattus norvegicus 80.38 0.00e+00 1966.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.38 2.00e-40 161.00
IUUC-Sha-106962 Sarcophilus harrisii 82.52 0.00e+00 1959.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 33.40 5.00e-66 246.00
IUUC-Spo-108170 Schizosaccharomyces pombe 31.26 1.00e-66 248.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 31.44 4.00e-91 330.00
IUUC-Smo-109554 Selaginella moellendorffii 36.46 1.00e-85 311.00
IUUC-Sit-110479 Setaria italica 35.40 2.00e-70 261.00
IUUC-Sly-111752 Solanum lycopersicum 32.59 2.00e-90 327.00
IUUC-Sar-113304 Sorex araneus 85.64 0.00e+00 2014.00
IUUC-Sbi-114196 Sorghum bicolor 41.69 2.00e-70 260.00
IUUC-Sre-115151 Sporisorium reilianum 31.34 4.00e-85 310.00
IUUC-Ssc-116104 Sus scrofa 86.40 0.00e+00 2068.00
IUUC-Tgu-117438 Taeniopygia guttata 75.55 0.00e+00 1753.00
IUUC-Tru-118553 Takifugu rubripes 46.88 0.00e+00 994.00
IUUC-Tsy-119056 Tarsius syrichta 86.62 0.00e+00 2013.00
IUUC-Tni-119933 Tetraodon nigroviridis 47.34 0.00e+00 949.00
IUUC-Tca-121376 Theobroma cacao 30.46 7.00e-114 405.00
IUUC-Tre-121972 Trichoderma reesei 30.81 3.00e-83 303.00
IUUC-Tvi-122342 Trichoderma virens 35.50 1.00e-80 295.00
IUUC-Tae-123898 Triticum aestivum 34.17 2.00e-88 320.00
IUUC-Tur-126735 Triticum urartu 26.56 5.00e-36 146.00
IUUC-Tme-126999 Tuber melanosporum 33.00 1.00e-80 295.00
IUUC-Tbe-127280 Tupaia belangeri 88.25 1.00e-140 494.00
IUUC-Ttr-129104 Tursiops truncatus 86.06 0.00e+00 2066.00
IUUC-Uma-129562 Ustilago maydis 30.99 2.00e-85 311.00
IUUC-Vda-129862 Verticillium dahliae 31.19 2.00e-91 331.00
IUUC-Vpa-130819 Vicugna pacos 83.56 0.00e+00 1094.00
IUUC-Vvi-131111 Vitis vinifera 35.00 1.00e-84 308.00
IUUC-Xtr-132629 Xenopus tropicalis 63.32 0.00e+00 1426.00
IUUC-Xma-134065 Xiphophorus maculatus 51.33 0.00e+00 794.00
IUUC-Yli-134633 Yarrowia lipolytica 32.67 2.00e-62 234.00
IUUC-Zma-135176 Zea mays 36.55 4.00e-86 313.00
Created Date 25-Jun-2017

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