iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027304

Ensembl Protein ID

CMC064CT

UniProt Accession

M1VEQ5; M1VEQ5_CYAM1

Genbank Protein ID

BAM79003.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

AP006485

Gene Name

CYME_CMC064C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMC064C	CMC064CT	CMC064CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-30	101.8	50	86
UBD/Beta-Prp	2.00e-41	140.2	9	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtgvl 35
           gHt+ v++++ f ++t+l++Gs D+t ++WD+ tg+ 
   Q: 50   GHTGAVWSCDvFwDSTRLLTGSADNTARLWDVQTGRE 86
           8********966644*******************986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           h+ ++t +kf p+++ll+t+ +d + +vw ++tg  l ++ gh+++v++++   d+  l+tgs D+t+++wd++tg  +  ++   +sv+s+ + p     
   Q: 9    HERPLTQLKFNPEGDLLFTTAKDTRPTVWWASTGERLGTYDGHTGAVWSCDVFWDSTRLLTGSADNTARLWDVQTGRELFRWS-LRSSVRSVGVAP----- 103
           34455556666666666666666666666666666666666666666666655555566666666666666666666666666.556666655554..... PP
   S: 110  vsGshdrtirvwdletgqclee......................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
                                                                       +l+gh++++++vv+  ++ ++ s s D+tvr Wd++tgk +
   Q: 104  ---------------------GcrlmhlanskllgqescihlfrlksdgnwqeqetepflVLRGHTATITGVVWYNTAEYMLSVSEDGTVRKWDVETGKEV 183
           .....................044444444444444444444444444444448889999***************************************** PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq...tgec......................................................vr 216
           ++ +  h+++++ ++f+++ + +++gs dgt  lwd +   +  +                                                      + 
   Q: 184  DRAKR-HKKAITDIKFSKDHQMFLTGSADGTAVLWDTHamqE--IrsfvldrplnavdlsplmphavvgggqeasqvtttagkagkfaatflhliygeeIF 281
           ***98.*******************************97550..244555556666666666677777777778888888888899999999999999999 PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++gh  +++++ f+p++  ++sg++Dg +r++
   Q: 282  SVKGHFGPINCLSFTPDGRGFASGGEDGYVRLH 314
           99****************************997 PP

Organism

Cyanidioschyzon merolae

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPLLLKGHE RPLTQLKFNP EGDLLFTTAK DTRPTVWWAS TGERLGTYDG HTGAVWSCDV 60
FWDSTRLLTG SADNTARLWD VQTGRELFRW SLRSSVRSVG VAPGCRLMHL ANSKLLGQES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGCCGC TGCTTTTGAA AGGGCATGAG CGCCCGCTGA CCCAGCTCAA GTTCAATCCT 60
GAAGGGGACC TGCTCTTTAC AACCGCGAAA GATACGCGCC CAACGGTATG GTGGGCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

cme:CYME_CMC064C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	29.84	5.00e-35	139.00
IUUC-Aml-001321	Ailuropoda melanoleuca	44.86	4.00e-85	305.00
IUUC-Atr-002468	Amborella trichopoda	52.88	8.00e-54	201.00
IUUC-Apl-003841	Anas platyrhynchos	45.17	9.00e-88	314.00
IUUC-Aca-005123	Anolis carolinensis	45.34	5.00e-88	315.00
IUUC-Aly-005473	Arabidopsis lyrata	51.38	9.00e-92	327.00
IUUC-Ath-007094	Arabidopsis thaliana	51.07	2.00e-91	327.00
IUUC-Ago-008000	Ashbya gossypii	38.96	3.00e-68	249.00
IUUC-Acl-008098	Aspergillus clavatus	41.32	5.00e-76	275.00
IUUC-Afl-008494	Aspergillus flavus	41.82	3.00e-77	279.00
IUUC-Afu-009080	Aspergillus fumigatus	41.14	2.00e-76	276.00
IUUC-Ani-009230	Aspergillus nidulans	41.34	9.00e-78	281.00
IUUC-Aor-010114	Aspergillus oryzae	41.82	3.00e-77	279.00
IUUC-Ate-010285	Aspergillus terreus	41.34	6.00e-79	285.00
IUUC-Ame-011534	Astyanax mexicanus	45.79	3.00e-90	322.00
IUUC-Bgr-012121	Blumeria graminis	38.79	1.00e-66	244.00
IUUC-Bta-013143	Bos taurus	45.03	9.00e-86	307.00
IUUC-Bci-013950	Botrytis cinerea	39.70	8.00e-74	268.00
IUUC-Bdi-015019	Brachypodium distachyon	53.40	5.00e-97	345.00
IUUC-Bol-015709	Brassica oleracea	50.30	7.00e-89	319.00
IUUC-Bra-018077	Brassica rapa	49.42	8.00e-90	321.00
IUUC-Cel-018226	Caenorhabditis elegans	35.60	8.00e-63	231.00
IUUC-Cja-019741	Callithrix jacchus	45.03	4.00e-86	308.00
IUUC-Cfa-021204	Canis familiaris	44.55	7.00e-85	304.00
IUUC-Cpo-021661	Cavia porcellus	44.86	2.00e-85	306.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	44.24	2.00e-83	300.00
IUUC-Csa-024038	Chlorocebus sabaeus	45.03	4.00e-86	308.00
IUUC-Cho-024856	Choloepus hoffmanni	26.67	3.00e-19	86.70
IUUC-Cin-025597	Ciona intestinalis	44.00	3.00e-83	299.00
IUUC-Csv-026287	Ciona savignyi	32.39	6.00e-37	145.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	38.97	4.00e-70	255.00
IUUC-Cne-026838	Cryptococcus neoformans	41.03	3.00e-75	273.00
IUUC-Dre-028567	Danio rerio	44.24	2.00e-88	316.00
IUUC-Dno-029171	Dasypus novemcinctus	45.00	2.00e-84	304.00
IUUC-Dor-030257	Dipodomys ordii	33.15	4.00e-27	112.00
IUUC-Dse-031191	Dothistroma septosporum	39.09	6.00e-72	261.00
IUUC-Dme-031879	Drosophila melanogaster	44.92	5.00e-84	301.00
IUUC-Ete-032336	Echinops telfairi	35.19	1.00e-39	153.00
IUUC-Eca-033259	Equus caballus	44.86	3.00e-85	305.00
IUUC-Eeu-035153	Erinaceus europaeus	37.06	2.00e-24	103.00
IUUC-Fca-036489	Felis catus	44.86	3.00e-85	305.00
IUUC-Fal-037485	Ficedula albicollis	45.17	4.00e-88	315.00
IUUC-Fox-037860	Fusarium oxysporum	40.00	4.00e-73	265.00
IUUC-Fso-038188	Fusarium solani	39.09	4.00e-70	255.00
IUUC-Gmo-039311	Gadus morhua	44.06	1.00e-86	310.00
IUUC-Ggr-040045	Gaeumannomyces graminis	42.60	5.00e-76	275.00
IUUC-Gga-040645	Gallus gallus	44.24	2.00e-86	309.00
IUUC-Gac-042086	Gasterosteus aculeatus	46.42	8.00e-89	317.00
IUUC-Gma-043930	Glycine max	53.09	5.00e-98	348.00
IUUC-Ggo-045578	Gorilla gorilla	45.03	4.00e-86	308.00
IUUC-Hsa-046734	Homo sapiens	45.03	4.00e-86	308.00
IUUC-Hvu-047553	Hordeum vulgare	53.70	3.00e-97	345.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	44.86	4.00e-85	305.00
IUUC-Kpa-049325	Komagataella pastoris	42.11	1.00e-78	283.00
IUUC-Lch-049620	Latimeria chalumnae	44.33	5.00e-79	285.00
IUUC-Lpe-051338	Leersia perrieri	50.16	9.00e-88	314.00
IUUC-Loc-052094	Lepisosteus oculatus	39.39	2.00e-74	270.00
IUUC-Lma-053047	Leptosphaeria maculans	40.92	6.00e-73	265.00
IUUC-Laf-053801	Loxodonta africana	44.76	1.00e-82	296.00
IUUC-Mcc-055498	Macaca mulatta	38.51	2.00e-64	236.00
IUUC-Meu-056729	Macropus eugenii	40.56	6.00e-73	265.00
IUUC-Mor-057025	Magnaporthe oryzae	42.60	4.00e-75	272.00
IUUC-Mpo-057511	Magnaporthe poae	43.20	2.00e-76	276.00
IUUC-Mtr-058051	Medicago truncatula	52.00	2.00e-96	343.00
IUUC-Mla-059061	Melampsora laricipopulina	42.28	3.00e-72	262.00
IUUC-Mga-059229	Meleagris gallopavo	44.58	2.00e-85	306.00
IUUC-Mvi-060399	Microbotryum violaceum	38.55	3.00e-68	249.00
IUUC-Mmr-060764	Microcebus murinus	45.03	3.00e-86	309.00
IUUC-Mdo-062088	Monodelphis domestica	45.03	4.00e-85	305.00
IUUC-Mmu-064304	Mus musculus	45.03	6.00e-86	308.00
IUUC-Mac-065520	Musa acuminata	52.35	1.00e-94	337.00
IUUC-Mpu-066340	Mustela putorius furo	44.86	3.00e-85	305.00
IUUC-Mlu-067111	Myotis lucifugus	44.86	2.00e-85	306.00
IUUC-Nfi-068478	Neosartorya fischeri	41.44	4.00e-76	275.00
IUUC-Ncr-068820	Neurospora crassa	40.79	1.00e-70	257.00
IUUC-Nle-069903	Nomascus leucogenys	44.86	2.00e-85	306.00
IUUC-Opr-070221	Ochotona princeps	44.41	3.00e-83	299.00
IUUC-Ont-071765	Oreochromis niloticus	45.79	1.00e-90	323.00
IUUC-Oan-073660	Ornithorhynchus anatinus	42.21	4.00e-71	258.00
IUUC-Ocu-074039	Oryctolagus cuniculus	44.86	2.00e-85	306.00
IUUC-Oba-075395	Oryza barthii	48.46	3.00e-83	298.00
IUUC-Obr-076334	Oryza brachyantha	50.93	4.00e-90	322.00
IUUC-Ogl-077751	Oryza glaberrima	53.40	3.00e-97	345.00
IUUC-Ogu-078207	Oryza glumaepatula	52.78	2.00e-96	342.00
IUUC-Oin-079878	Oryza indica	53.09	4.00e-97	345.00
IUUC-Olo-080677	Oryza longistaminata	45.77	4.00e-88	315.00
IUUC-Ome-081228	Oryza meridionalis	41.53	2.00e-45	173.00
IUUC-Oni-082411	Oryza nivara	47.53	9.00e-81	290.00
IUUC-Opu-083136	Oryza punctata	53.09	7.00e-97	344.00
IUUC-Oru-084916	Oryza rufipogon	51.95	9.00e-95	337.00
IUUC-Osa-085776	Oryza sativa	53.40	3.00e-97	345.00
IUUC-Ola-087053	Oryzias latipes	44.55	2.00e-88	316.00
IUUC-Olu-087602	Ostreococcus lucimarinus	46.58	6.00e-86	308.00
IUUC-Oga-088154	Otolemur garnettii	44.86	2.00e-85	306.00
IUUC-Oar-089915	Ovis aries	44.86	4.00e-85	305.00
IUUC-Ptr-091124	Pan troglodytes	38.75	2.00e-61	226.00
IUUC-Pan-092035	Papio anubis	45.03	4.00e-86	308.00
IUUC-Psi-094096	Pelodiscus sinensis	40.85	5.00e-49	184.00
IUUC-Pma-094255	Petromyzon marinus	31.53	4.00e-31	125.00
IUUC-Pno-094988	Phaeosphaeria nodorum	40.00	1.00e-66	244.00
IUUC-Ppa-095949	Physcomitrella patens	50.93	4.00e-94	335.00
IUUC-Pfo-096101	Poecilia formosa	45.48	3.00e-90	322.00
IUUC-Pab-097726	Pongo abelii	45.03	4.00e-86	308.00
IUUC-Pop-099617	Populus trichocarpa	51.38	1.00e-92	330.00
IUUC-Pca-101014	Procavia capensis	45.03	5.00e-86	308.00
IUUC-Ppe-101320	Prunus persica	53.09	1.00e-96	343.00
IUUC-Pva-102789	Pteropus vampyrus	42.37	1.00e-75	274.00
IUUC-Pgr-103479	Puccinia graminis	42.28	6.00e-74	268.00
IUUC-Ptt-103981	Puccinia triticina	42.28	1.00e-73	267.00
IUUC-Pte-104278	Pyrenophora teres	41.09	5.00e-72	261.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	41.09	5.00e-72	261.00
IUUC-Rno-105867	Rattus norvegicus	42.59	2.00e-71	259.00
IUUC-Sce-106251	Saccharomyces cerevisiae	40.12	4.00e-72	262.00
IUUC-Sha-107039	Sarcophilus harrisii	44.72	6.00e-85	305.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	43.21	9.00e-79	284.00
IUUC-Spo-108314	Schizosaccharomyces pombe	42.90	7.00e-80	288.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	39.70	9.00e-74	267.00
IUUC-Smo-108728	Selaginella moellendorffii	52.62	3.00e-96	342.00
IUUC-Sit-110801	Setaria italica	51.23	1.00e-92	330.00
IUUC-Sly-111326	Solanum lycopersicum	53.54	1.00e-97	346.00
IUUC-Stu-112458	Solanum tuberosum	53.54	2.00e-97	346.00
IUUC-Sbi-114063	Sorghum bicolor	50.93	1.00e-91	327.00
IUUC-Sre-115096	Sporisorium reilianum	38.97	6.00e-67	245.00
IUUC-Ssc-116080	Sus scrofa	45.03	8.00e-86	307.00
IUUC-Tgu-116988	Taeniopygia guttata	45.17	4.00e-88	315.00
IUUC-Tru-118766	Takifugu rubripes	45.48	6.00e-90	321.00
IUUC-Tsy-119522	Tarsius syrichta	28.75	3.00e-22	97.10
IUUC-Tni-120197	Tetraodon nigroviridis	45.79	2.00e-90	323.00
IUUC-Tca-121316	Theobroma cacao	54.63	1.00e-98	350.00
IUUC-Tre-122097	Trichoderma reesei	41.39	2.00e-74	269.00
IUUC-Tvi-122442	Trichoderma virens	40.79	2.00e-73	266.00
IUUC-Tae-125542	Triticum aestivum	53.40	1.00e-97	346.00
IUUC-Tur-126334	Triticum urartu	45.99	9.00e-76	274.00
IUUC-Tme-127038	Tuber melanosporum	42.55	2.00e-77	279.00
IUUC-Ttr-128659	Tursiops truncatus	42.06	1.00e-66	244.00
IUUC-Uma-129464	Ustilago maydis	38.97	1.00e-66	244.00
IUUC-Vda-129841	Verticillium dahliae	41.82	2.00e-72	263.00
IUUC-Vpa-130382	Vicugna pacos	30.25	4.00e-29	119.00
IUUC-Vvi-131076	Vitis vinifera	51.54	1.00e-94	337.00
IUUC-Xtr-132395	Xenopus tropicalis	44.86	1.00e-86	310.00
IUUC-Xma-133383	Xiphophorus maculatus	45.48	8.00e-90	321.00
IUUC-Yli-134586	Yarrowia lipolytica	40.92	4.00e-67	245.00
IUUC-Zma-135904	Zea mays	51.54	1.00e-92	330.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence