iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125385

Ensembl Protein ID

TRIAE_CS42_6AS_TGACv1_486272_AA1559050.3

UniProt Accession

A0A1D6AGW5; A0A1D6AGW5_WHEAT

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_6AS_TGACv1_486272_AA1559050	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.1	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.1
TRIAE_CS42_6AS_TGACv1_486272_AA1559050	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.2	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.2
TRIAE_CS42_6AS_TGACv1_486272_AA1559050	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.3	TRIAE_CS42_6AS_TGACv1_486272_AA1559050.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-31	108.3	185	226
UBD/Beta-Prp	1.00e-64	221.3	16	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 185  GHSKGVNCVDYftgGDrPFLITGSDDQTAKVWDYQTKSCVQT 226
           8********966997789******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtik 77
           +++++++ + +p +++++++ ++g++ +w+++t+++++s++  e +v++ kf+ ++++ v g++D++i+
   Q: 16   RSERVKSADLHPTEPWILSSLYSGSVCIWNYQTQTMVKSFEVTELPVRSAKFIARKQWVVAGADDMFIR 84
           5678899999*********************************************************** PP
   S: 78   vwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvh 146
           v++++t + v ++++h+d++++++++p++ +++s s+d  i++wd+++g+   ++++gh++ v+ v+++
   Q: 85   VYNYNTMDKVKVFEAHTDYIRCVAVHPTQPFVLSSSDDMLIKLWDWDKGWACTHIFEGHSHYVMQVTFN 153
           **************************************************9989*************** PP
   S: 147  pdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtg 212
           p++ n ++s+slDrt+++W++ + +   tl g h + v++++     ++++l++gs+d+t k+wd+qt+
   Q: 154  PKDtNTFASASLDRTIKIWSIGSPDPNFTLDG-HSKGVNCVDyfTGGDRPFLITGSDDQTAKVWDYQTK 221
           *******************************9.*********7445566******************** PP
   S: 213  ecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlv 281
           +cv+tl+gh  nv+ v f+p+  ++++gs+Dg++r+W +++  l +tl++  ++v++  +++ ++++++
   Q: 222  SCVQTLEGHAHNVSAVCFHPELPIIITGSEDGTVRLWHSTTYRLENTLNYGLERVWALGYMKGSRRIVI 290
           ********************************************************9998665555553 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MWQPLRLDIK RKLAQRSERV KSADLHPTEP WILSSLYSGS VCIWNYQTQT MVKSFEVTEL 60
PVRSAKFIAR KQWVVAGADD MFIRVYNYNT MDKVKVFEAH TDYIRCVAVH PTQPFVLSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTAGCTAC TACGTCAGCA GGAGAAGTCA ACATCGGAAA GGCAACAGTG CAACACACGC 60
GCACACACAC ACAACCTTCA GATCCAATCG ACCATACTAC TGCCTCCGAG CGACCGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000222	Aegilops tauschii	95.27	0.00e+00	1113.00
IUUC-Bdi-015046	Brachypodium distachyon	95.66	0.00e+00	1773.00
IUUC-Hvu-047669	Hordeum vulgare	100.00	0.00e+00	756.00
IUUC-Lpe-051579	Leersia perrieri	89.88	0.00e+00	1641.00
IUUC-Mla-058937	Melampsora laricipopulina	51.93	0.00e+00	882.00
IUUC-Nfi-068277	Neosartorya fischeri	52.00	0.00e+00	880.00
IUUC-Oba-075751	Oryza barthii	85.20	0.00e+00	1580.00
IUUC-Obr-076163	Oryza brachyantha	90.95	0.00e+00	1680.00
IUUC-Oin-079856	Oryza indica	89.80	0.00e+00	1644.00
IUUC-Ome-081554	Oryza meridionalis	85.57	0.00e+00	1552.00
IUUC-Opu-083400	Oryza punctata	88.09	0.00e+00	1650.00
IUUC-Oru-085196	Oryza rufipogon	87.72	0.00e+00	1598.00
IUUC-Sit-110692	Setaria italica	90.68	0.00e+00	1639.00
IUUC-Sbi-113801	Sorghum bicolor	88.91	0.00e+00	1641.00
IUUC-Tni-120142	Tetraodon nigroviridis	59.88	0.00e+00	1083.00
IUUC-Yli-134455	Yarrowia lipolytica	49.62	0.00e+00	800.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence