iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0004870	FBtr0333270	FBpp0305468
FBgn0004870	FBtr0333268	FBpp0305466
FBgn0004870	FBtr0333269	FBpp0305467
FBgn0004870	FBtr0072642	FBpp0072538

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.30e-10	39.1	128	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l ++g+  +ahk vL+a+S++F+ l+       + ++ v ++dv  + ++a+++F+Y g+++ 
   Q: 128  DVTLACDGRSMKAHKMVLSACSPYFQTLLAETPC--Q-HPIVIMRDVNWSDLKAIVEFMYRGEINV 190
           9****************************44333..3.799*********************9875 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Probably acts as a transcriptional regulator. Required for the specification of the tarsal segment. Also involved in antenna development.

Protein Sequence
(Fasta)

MASAQAETNV GLASEQGPVA QRQRKGTGSG ADSPKSNRSS PTQQEEKRIK SEDRTSPTGG 60
AKDEDKESQG HAVAGGGGSS PVSSPQGRSS SVASPSSSSQ QFCLRWNNYQ TNLTTIFDQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGTGCTGA GAAGACTTTT GGCCCTGTTT GTTGGCCAAT ACAGCCATAG AACACTGAAA 60
CCGAAACAGA AACAGAAACG GAACTGAAAG CACACACTGA ATAACACTGG ACACGACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR000210--BTB/POZ_dom
IPR009057--Homeobox-like
IPR007889--HTH_Psq
IPR011333--SKP1/BTB/POZ
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE

PS50097--BTB
PS50960--HTH_PSQ

Pfam

PF00651--BTB
PF05225--HTH_psq

SMART

SM00225--BTB

Gene Ontology

GO:0005634--C:nucleus
GO:0003680--F:AT DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0048085--P:adult chitin-containing cuticle pigmentation
GO:0007455--P:eye-antennal disc morphogenesis
GO:0046660--P:female sex differentiation
GO:0007478--P:leg disc morphogenesis
GO:0048086--P:negative regulation of developmental pigmentation
GO:0048092--P:negative regulation of male pigmentation
GO:0048070--P:regulation of developmental pigmentation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007548--P:sex differentiation
GO:0048071--P:sex-specific pigmentation
GO:0006351--P:transcription, DNA-templated

KEGG

dme:Dmel_CG9097

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Mla-058979	Melampsora laricipopulina	29.41	6.80e+00	25.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence