• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Tni-120109
Ensembl Protein ID ENSTNIP00000016187.1
UniProt Accession H3D6P6; H3D6P6_TETNG
Protein Name Ubiquitin-related modifier 1
Gene Name urm1; URM1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTNIG00000013204.1 ENSTNIT00000016398.1 ENSTNIP00000016187.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 37.00 5.00e-12 63.50 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Tetraodon nigroviridis
Functional Description
(View)

Functional Description


     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
 Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MAAPVAVHLE FGGGAELLFN GVKEHHVTLP GQSGPWDMKQ LLVWIQQNLL KERPELFVQG 60
QSVRDHGILV LINDADWELM GELEYQLQDQ DNVVFISTLH GG 102
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tni-120109|ULD,UBQ_Other|Tetraodon nigroviridis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGGCGC CCGTTGCGGT TCATCTGGAA TTCGGGTGAG TGAATTAAGC GCTTTAGTTC 60
TTTTTAACCC GTCCTTATAA TGCCATTTCA TCAACAGTTA AACGTCAGTA AAATGGCGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tni-120109|ULD,UBQ_Other|Tetraodon nigroviridis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway
Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1
Pfam

PF09138--Urm1
Gene Ontology

GO:0005829--C:cytosol
GO:0032447--P:protein urmylation
GO:0034227--P:tRNA thio-modification
GO:0002098--P:tRNA wobble uridine modification
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 76.47 5.00e-43 164.00
IUUC-Atr-003089 Amborella trichopoda 57.14 4.00e-28 115.00
IUUC-Apl-003382 Anas platyrhynchos 78.26 1.00e-37 147.00
IUUC-Aca-004981 Anolis carolinensis 78.43 1.00e-43 166.00
IUUC-Aly-005517 Arabidopsis lyrata 53.76 2.00e-24 103.00
IUUC-Ath-006718 Arabidopsis thaliana 52.94 5.00e-21 92.00
IUUC-Ago-007917 Ashbya gossypii 42.00 2.00e-17 80.10
IUUC-Acl-008054 Aspergillus clavatus 64.71 2.00e-13 66.20
IUUC-Afl-008704 Aspergillus flavus 52.22 1.00e-18 84.00
IUUC-Aor-009890 Aspergillus oryzae 51.96 3.00e-22 96.30
IUUC-Bta-012448 Bos taurus 77.45 3.00e-43 165.00
IUUC-Bci-013865 Botrytis cinerea 42.16 4.00e-18 82.40
IUUC-Bdi-014980 Brachypodium distachyon 61.97 2.00e-21 93.60
IUUC-Bol-016055 Brassica oleracea 54.55 6.00e-21 91.70
IUUC-Bra-016845 Brassica rapa 54.55 6.00e-21 91.70
IUUC-Cel-018485 Caenorhabditis elegans 31.07 2.00e-10 57.00
IUUC-Cja-019587 Callithrix jacchus 78.43 3.00e-43 166.00
IUUC-Cfa-020653 Canis familiaris 76.47 4.00e-43 165.00
IUUC-Cpo-021622 Cavia porcellus 78.43 3.00e-43 166.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 55.56 3.00e-24 102.00
IUUC-Csa-023756 Chlorocebus sabaeus 75.00 3.00e-31 127.00
IUUC-Cgl-026518 Colletotrichum gloeosporioides 42.16 3.00e-18 82.80
IUUC-Cne-026953 Cryptococcus neoformans 53.92 3.00e-24 103.00
IUUC-Cme-027314 Cyanidioschyzon merolae 40.40 2.00e-17 79.30
IUUC-Dre-027884 Danio rerio 82.35 4.00e-45 171.00
IUUC-Dno-029262 Dasypus novemcinctus 74.07 3.00e-31 127.00
IUUC-Dor-030601 Dipodomys ordii 52.94 2.00e-22 96.30
IUUC-Dme-031893 Drosophila melanogaster 57.28 1.00e-27 114.00
IUUC-Ete-032773 Echinops telfairi 74.51 2.00e-40 156.00
IUUC-Eca-034187 Equus caballus 77.45 4.00e-43 165.00
IUUC-Eeu-034808 Erinaceus europaeus 73.53 1.00e-41 160.00
IUUC-Fca-036107 Felis catus 76.47 3.00e-43 166.00
IUUC-Fal-036607 Ficedula albicollis 78.26 1.00e-37 146.00
IUUC-Fox-037698 Fusarium oxysporum 46.67 6.00e-20 88.60
IUUC-Gmo-039492 Gadus morhua 83.33 4.00e-45 171.00
IUUC-Ggr-039965 Gaeumannomyces graminis 44.76 6.00e-17 79.30
IUUC-Gga-041268 Gallus gallus 78.43 4.00e-43 165.00
IUUC-Gac-042111 Gasterosteus aculeatus 87.25 1.00e-47 180.00
IUUC-Gma-043240 Glycine max 56.10 2.00e-20 90.10
IUUC-Ggo-045176 Gorilla gorilla 73.75 2.00e-24 103.00
IUUC-Hsa-046077 Homo sapiens 76.47 2.00e-36 142.00
IUUC-Itr-048111 Ictidomys tridecemlineatus 78.89 1.00e-30 124.00
IUUC-Kpa-049157 Komagataella pastoris 47.00 7.00e-18 81.30
IUUC-Lch-049889 Latimeria chalumnae 78.43 2.00e-44 169.00
IUUC-Lpe-050783 Leersia perrieri 64.06 3.00e-19 85.90
IUUC-Loc-052400 Lepisosteus oculatus 80.39 2.00e-44 169.00
IUUC-Lma-053259 Leptosphaeria maculans 44.12 1.00e-17 80.90
IUUC-Laf-053596 Loxodonta africana 77.88 3.00e-42 162.00
IUUC-Mcc-054845 Macaca mulatta 72.73 7.00e-38 147.00
IUUC-Meu-055968 Macropus eugenii 77.45 4.00e-43 165.00
IUUC-Mor-057126 Magnaporthe oryzae 42.86 1.00e-15 74.70
IUUC-Mpo-057311 Magnaporthe poae 45.10 5.00e-18 83.20
IUUC-Mtr-058266 Medicago truncatula 61.54 3.00e-19 86.30
IUUC-Mla-058847 Melampsora laricipopulina 37.86 6.00e-10 55.80
IUUC-Mga-059468 Meleagris gallopavo 79.35 3.00e-38 148.00
IUUC-Mvi-060235 Microbotryum violaceum 35.53 5.00e-17 79.70
IUUC-Mdo-061948 Monodelphis domestica 76.47 1.00e-42 163.00
IUUC-Mmu-063946 Mus musculus 76.47 1.00e-42 163.00
IUUC-Mac-064812 Musa acuminata 66.15 4.00e-22 95.50
IUUC-Mpu-066763 Mustela putorius furo 76.47 4.00e-42 161.00
IUUC-Mlu-066970 Myotis lucifugus 76.25 9.00e-32 127.00
IUUC-Ncr-068824 Neurospora crassa 44.12 1.00e-17 80.90
IUUC-Nle-069849 Nomascus leucogenys 75.00 2.00e-31 127.00
IUUC-Opr-070227 Ochotona princeps 78.43 3.00e-43 166.00
IUUC-Ont-072530 Oreochromis niloticus 88.24 2.00e-47 179.00
IUUC-Oan-073191 Ornithorhynchus anatinus 77.78 3.00e-37 145.00
IUUC-Ocu-074460 Oryctolagus cuniculus 76.77 1.00e-41 160.00
IUUC-Oba-075499 Oryza barthii 64.62 7.00e-20 89.70
IUUC-Obr-076896 Oryza brachyantha 59.72 1.00e-19 89.70
IUUC-Ogl-077834 Oryza glaberrima 64.62 4.00e-20 89.00
IUUC-Ogu-078622 Oryza glumaepatula 64.62 4.00e-20 89.00
IUUC-Oin-079358 Oryza indica 64.62 7.00e-20 90.10
IUUC-Olo-081035 Oryza longistaminata 53.00 2.00e-21 94.40
IUUC-Oni-082425 Oryza nivara 64.62 4.00e-20 89.00
IUUC-Opu-083461 Oryza punctata 64.06 2.00e-19 87.80
IUUC-Oru-084875 Oryza rufipogon 57.75 9.00e-19 84.00
IUUC-Oga-089128 Otolemur garnettii 77.45 4.00e-43 165.00
IUUC-Oar-089896 Ovis aries 77.45 3.00e-43 165.00
IUUC-Ptr-091618 Pan troglodytes 73.75 3.00e-24 103.00
IUUC-Pan-092238 Papio anubis 75.00 2.00e-31 127.00
IUUC-Psi-093879 Pelodiscus sinensis 75.49 1.00e-41 160.00
IUUC-Pma-094484 Petromyzon marinus 72.55 7.00e-31 124.00
IUUC-Ppa-095801 Physcomitrella patens 58.23 1.00e-20 90.90
IUUC-Pfo-097192 Poecilia formosa 89.22 4.00e-48 181.00
IUUC-Pab-098203 Pongo abelii 76.47 3.00e-36 142.00
IUUC-Pop-099614 Populus trichocarpa 52.94 2.00e-20 90.10
IUUC-Pca-100507 Procavia capensis 75.00 1.00e-31 126.00
IUUC-Ppe-101174 Prunus persica 56.00 2.00e-26 110.00
IUUC-Pva-102735 Pteropus vampyrus 76.47 3.00e-40 155.00
IUUC-Pgr-103510 Puccinia graminis 35.92 6.00e-09 52.40
IUUC-Ptt-103918 Puccinia triticina 35.92 2.00e-08 50.80
IUUC-Pte-104173 Pyrenophora teres 46.15 3.00e-19 86.30
IUUC-Pyt-104806 Pyrenophora triticirepentis 46.15 2.00e-19 86.70
IUUC-Rno-105820 Rattus norvegicus 77.45 6.00e-43 164.00
IUUC-Sce-106366 Saccharomyces cerevisiae 37.00 2.00e-12 63.50
IUUC-Sja-107727 Schizosaccharomyces japonicus 41.24 4.00e-14 69.70
IUUC-Spo-108074 Schizosaccharomyces pombe 41.58 6.00e-09 51.60
IUUC-Smo-108944 Selaginella moellendorffii 62.22 6.00e-25 104.00
IUUC-Sit-110277 Setaria italica 57.65 1.00e-21 94.00
IUUC-Sly-111505 Solanum lycopersicum 55.29 3.00e-22 96.30
IUUC-Stu-112076 Solanum tuberosum 55.29 3.00e-22 95.90
IUUC-Sbi-114274 Sorghum bicolor 64.62 1.00e-20 90.90
IUUC-Sre-114953 Sporisorium reilianum 56.31 1.00e-23 100.00
IUUC-Ssc-115418 Sus scrofa 77.45 4.00e-43 165.00
IUUC-Tgu-117311 Taeniopygia guttata 78.26 1.00e-37 146.00
IUUC-Tru-118598 Takifugu rubripes 93.33 1.00e-42 163.00
IUUC-Tca-120942 Theobroma cacao 53.57 7.00e-21 91.30
IUUC-Tre-122099 Trichoderma reesei 46.32 3.00e-12 62.80
IUUC-Tvi-122285 Trichoderma virens 47.62 5.00e-16 75.90
IUUC-Tae-125193 Triticum aestivum 64.62 4.00e-20 89.00
IUUC-Tur-126677 Triticum urartu 55.26 9.00e-19 84.70
IUUC-Tme-127120 Tuber melanosporum 46.67 2.00e-21 94.00
IUUC-Tbe-128050 Tupaia belangeri 57.84 6.00e-26 108.00
IUUC-Ttr-129019 Tursiops truncatus 74.51 7.00e-40 154.00
IUUC-Uma-129483 Ustilago maydis 53.40 8.00e-21 91.30
IUUC-Vda-129690 Verticillium dahliae 37.50 3.00e-13 66.20
IUUC-Vvi-131174 Vitis vinifera 54.76 1.00e-20 90.90
IUUC-Xma-133862 Xiphophorus maculatus 89.22 4.00e-48 181.00
IUUC-Yli-134398 Yarrowia lipolytica 43.88 9.00e-16 74.30
IUUC-Zma-134964 Zea mays 55.81 3.00e-20 89.70
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved