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Tag Content
iUUCD ID IUUC-Zma-134964
Ensembl Protein ID Zm00001d021359_T001
UniProt Accession B6SXH2; URM1_MAIZE
Genbank Protein ID ACG29555.1
Protein Name Ubiquitin-related modifier 1 homolog
Genbank Nucleotide ID EU957437
Gene Name URM1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Zm00001d021359 Zm00001d021359_T002 Zm00001d021359_T002
Zm00001d021359 Zm00001d021359_T001 Zm00001d021359_T001
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 40.48 3.00e-12 64.30 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Zea mays
Functional Description
(View)

Functional Description



     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MHLTLEFGGG LELLLENSTK VHKVEVTTPK DGQGKVTMKF LLSWVKENLI KERPEMFLKA 60
DSVRPGVLVL INDCDWELCG GLDAELEEKD VVVFISTLHG G 101
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Protein Fasta Sequence



>IUUC-Zma-134964|ULD,UBQ_Other|Zea mays
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Nucleotide Sequence
(Fasta)
AGCCGGTCAC AGCGCGCAGC GCCGTCTCCT GCGATTCCCG GCTGCCTCCA CCTCTTCTCC 60
CACAGCGCCG GCGTGCTCCT CTCCTTTCAC GCTACGTTCC CTCCGGCCCC GGCGTCGACG 120
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Nucleotide Fasta Sequence



>IUUC-Zma-134964|ULD,UBQ_Other|Zea mays
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway

Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1

Pfam

PF09138--Urm1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0034227--P:tRNA thio-modification

KEGG zma:100275675
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 53.92 1.00e-25 107.00
IUUC-Atr-003089 Amborella trichopoda 69.31 6.00e-37 144.00
IUUC-Apl-003382 Anas platyrhynchos 54.74 6.00e-24 101.00
IUUC-Aca-004981 Anolis carolinensis 57.58 4.00e-27 112.00
IUUC-Aly-005517 Arabidopsis lyrata 67.02 2.00e-31 125.00
IUUC-Ath-006718 Arabidopsis thaliana 68.24 1.00e-29 120.00
IUUC-Ago-007917 Ashbya gossypii 39.81 2.00e-16 76.30
IUUC-Acl-008054 Aspergillus clavatus 58.00 8.00e-13 64.30
IUUC-Afl-008704 Aspergillus flavus 46.67 1.00e-17 80.10
IUUC-Aor-009890 Aspergillus oryzae 48.04 1.00e-21 94.00
IUUC-Bta-012448 Bos taurus 54.90 7.00e-26 107.00
IUUC-Bci-013865 Botrytis cinerea 41.18 2.00e-18 83.20
IUUC-Bdi-014980 Brachypodium distachyon 82.56 1.00e-35 140.00
IUUC-Bol-016055 Brassica oleracea 67.06 3.00e-29 119.00
IUUC-Bra-016845 Brassica rapa 67.06 3.00e-29 119.00
IUUC-Cel-018485 Caenorhabditis elegans 37.86 6.00e-12 61.60
IUUC-Cja-019587 Callithrix jacchus 55.88 5.00e-26 108.00
IUUC-Cfa-020653 Canis familiaris 53.92 9.00e-26 107.00
IUUC-Cpo-021622 Cavia porcellus 55.88 5.00e-26 108.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 52.58 2.00e-25 106.00
IUUC-Csa-023756 Chlorocebus sabaeus 51.28 3.00e-17 80.10
IUUC-Cgl-026518 Colletotrichum gloeosporioides 40.78 3.00e-16 75.90
IUUC-Cne-026953 Cryptococcus neoformans 50.94 2.00e-24 103.00
IUUC-Cme-027314 Cyanidioschyzon merolae 45.00 2.00e-18 83.20
IUUC-Dre-027884 Danio rerio 58.59 2.00e-27 113.00
IUUC-Dno-029262 Dasypus novemcinctus 51.22 3.00e-17 80.50
IUUC-Dor-030601 Dipodomys ordii 59.38 2.00e-15 73.20
IUUC-Dme-031893 Drosophila melanogaster 52.48 3.00e-24 102.00
IUUC-Ete-032773 Echinops telfairi 53.54 2.00e-25 106.00
IUUC-Eca-034187 Equus caballus 54.90 6.00e-26 107.00
IUUC-Eeu-034808 Erinaceus europaeus 51.96 4.00e-25 105.00
IUUC-Fca-036107 Felis catus 52.94 2.00e-25 106.00
IUUC-Fal-036607 Ficedula albicollis 53.68 3.00e-23 99.00
IUUC-Fox-037698 Fusarium oxysporum 36.27 5.00e-16 75.50
IUUC-Gmo-039492 Gadus morhua 58.59 9.00e-27 110.00
IUUC-Ggr-039965 Gaeumannomyces graminis 37.00 1.00e-15 74.70
IUUC-Gga-041268 Gallus gallus 55.56 3.00e-26 108.00
IUUC-Gac-042111 Gasterosteus aculeatus 55.56 1.00e-26 110.00
IUUC-Gma-043240 Glycine max 67.06 4.00e-29 118.00
IUUC-Ggo-045176 Gorilla gorilla 51.28 4.00e-11 59.70
IUUC-Hsa-046077 Homo sapiens 54.90 7.00e-20 87.80
IUUC-Itr-048111 Ictidomys tridecemlineatus 58.51 2.00e-18 82.80
IUUC-Kpa-049157 Komagataella pastoris 41.58 6.00e-15 71.20
IUUC-Lch-049889 Latimeria chalumnae 53.85 2.00e-24 103.00
IUUC-Lpe-050783 Leersia perrieri 85.71 1.00e-35 140.00
IUUC-Loc-052400 Lepisosteus oculatus 57.58 2.00e-26 109.00
IUUC-Lma-053259 Leptosphaeria maculans 41.00 1.00e-16 77.40
IUUC-Laf-053596 Loxodonta africana 55.77 1.00e-24 103.00
IUUC-Mcc-054845 Macaca mulatta 55.32 3.00e-23 99.00
IUUC-Meu-055968 Macropus eugenii 52.48 1.00e-25 107.00
IUUC-Mor-057126 Magnaporthe oryzae 39.42 1.00e-14 71.60
IUUC-Mpo-057311 Magnaporthe poae 36.27 4.00e-16 76.30
IUUC-Mtr-058266 Medicago truncatula 68.60 2.00e-29 119.00
IUUC-Mla-058847 Melampsora laricipopulina 37.38 4.00e-10 56.20
IUUC-Mga-059468 Meleagris gallopavo 54.74 2.00e-24 102.00
IUUC-Mvi-060235 Microbotryum violaceum 45.57 1.00e-14 71.60
IUUC-Mdo-061948 Monodelphis domestica 52.48 7.00e-26 107.00
IUUC-Mmu-063946 Mus musculus 52.53 4.00e-25 105.00
IUUC-Mac-064812 Musa acuminata 76.47 4.00e-33 131.00
IUUC-Mpu-066763 Mustela putorius furo 54.46 4.00e-26 108.00
IUUC-Mlu-066970 Myotis lucifugus 54.43 2.00e-17 79.30
IUUC-Ncr-068824 Neurospora crassa 41.75 3.00e-16 76.30
IUUC-Nle-069849 Nomascus leucogenys 51.28 6.00e-17 79.30
IUUC-Opr-070227 Ochotona princeps 55.88 5.00e-26 108.00
IUUC-Ont-072530 Oreochromis niloticus 59.60 4.00e-27 112.00
IUUC-Oan-073191 Ornithorhynchus anatinus 53.76 3.00e-23 99.00
IUUC-Ocu-074460 Oryctolagus cuniculus 53.92 2.00e-25 106.00
IUUC-Oba-075499 Oryza barthii 86.90 5.00e-37 146.00
IUUC-Obr-076896 Oryza brachyantha 85.71 3.00e-36 144.00
IUUC-Ogl-077834 Oryza glaberrima 86.90 4.00e-37 145.00
IUUC-Ogu-078622 Oryza glumaepatula 86.90 4.00e-37 145.00
IUUC-Oin-079358 Oryza indica 86.90 3.00e-37 147.00
IUUC-Olo-081035 Oryza longistaminata 85.57 6.00e-42 162.00
IUUC-Oni-082425 Oryza nivara 86.90 4.00e-37 145.00
IUUC-Opu-083461 Oryza punctata 85.88 1.00e-36 144.00
IUUC-Oru-084875 Oryza rufipogon 84.51 1.00e-28 116.00
IUUC-Oga-089128 Otolemur garnettii 54.90 5.00e-26 108.00
IUUC-Oar-089896 Ovis aries 54.90 7.00e-26 107.00
IUUC-Ptr-091618 Pan troglodytes 51.28 5.00e-11 59.70
IUUC-Pan-092238 Papio anubis 51.28 4.00e-17 80.10
IUUC-Psi-093879 Pelodiscus sinensis 55.45 2.00e-26 109.00
IUUC-Pma-094484 Petromyzon marinus 56.10 2.00e-22 96.70
IUUC-Ppa-095801 Physcomitrella patens 71.43 1.00e-29 120.00
IUUC-Pfo-097192 Poecilia formosa 56.70 8.00e-26 107.00
IUUC-Pab-098203 Pongo abelii 54.90 6.00e-20 88.20
IUUC-Pop-099614 Populus trichocarpa 71.76 2.00e-30 122.00
IUUC-Pca-100507 Procavia capensis 53.16 3.00e-17 79.00
IUUC-Ppe-101174 Prunus persica 71.29 1.00e-35 139.00
IUUC-Pva-102735 Pteropus vampyrus 53.92 2.00e-23 99.80
IUUC-Pgr-103510 Puccinia graminis 38.10 2.00e-11 60.10
IUUC-Ptt-103918 Puccinia triticina 37.38 7.00e-12 62.00
IUUC-Pte-104173 Pyrenophora teres 41.00 3.00e-18 82.80
IUUC-Pyt-104806 Pyrenophora triticirepentis 41.00 2.00e-18 83.20
IUUC-Rno-105820 Rattus norvegicus 57.14 2.00e-25 105.00
IUUC-Sce-106366 Saccharomyces cerevisiae 37.86 1.00e-14 70.50
IUUC-Sja-107727 Schizosaccharomyces japonicus 41.00 4.00e-12 62.80
IUUC-Spo-108074 Schizosaccharomyces pombe 38.46 6.00e-09 51.60
IUUC-Smo-108944 Selaginella moellendorffii 61.29 3.00e-25 105.00
IUUC-Sit-110277 Setaria italica 87.06 2.00e-37 145.00
IUUC-Sly-111505 Solanum lycopersicum 68.24 3.00e-29 119.00
IUUC-Stu-112076 Solanum tuberosum 68.24 4.00e-29 118.00
IUUC-Sbi-114274 Sorghum bicolor 82.11 9.00e-40 154.00
IUUC-Sre-114953 Sporisorium reilianum 50.00 1.00e-21 94.40
IUUC-Ssc-115418 Sus scrofa 54.90 5.00e-26 108.00
IUUC-Tgu-117311 Taeniopygia guttata 54.74 2.00e-23 99.40
IUUC-Tru-118598 Takifugu rubripes 56.99 1.00e-23 100.00
IUUC-Tni-120109 Tetraodon nigroviridis 58.16 7.00e-24 101.00
IUUC-Tca-120942 Theobroma cacao 72.62 1.00e-31 127.00
IUUC-Tre-122099 Trichoderma reesei 45.26 4.00e-13 65.10
IUUC-Tvi-122285 Trichoderma virens 45.63 4.00e-15 72.40
IUUC-Tae-125193 Triticum aestivum 84.52 7.00e-37 144.00
IUUC-Tur-126677 Triticum urartu 75.00 1.00e-34 137.00
IUUC-Tme-127120 Tuber melanosporum 42.00 9.00e-19 84.70
IUUC-Tbe-128050 Tupaia belangeri 39.60 1.00e-12 63.90
IUUC-Ttr-129019 Tursiops truncatus 54.46 5.00e-27 111.00
IUUC-Uma-129483 Ustilago maydis 48.04 4.00e-21 92.40
IUUC-Vda-129690 Verticillium dahliae 32.74 3.00e-10 56.20
IUUC-Vvi-131174 Vitis vinifera 73.81 1.00e-31 126.00
IUUC-Xma-133862 Xiphophorus maculatus 56.70 8.00e-26 107.00
IUUC-Yli-134398 Yarrowia lipolytica 42.45 3.00e-15 72.40
Created Date 25-Jun-2017

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