iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009756

Ensembl Protein ID

CAL00470

UniProt Accession

A2R767; A2R767_ASPNC

Genbank Protein ID

CAL00470.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

AM270360

Gene Name

An16g02460

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An16g02460	CAL00470	CAL00470

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-35	117.7	50	85
UBD/Beta-Prp	8.20e-76	254.5	3	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++ +l+vsG+dD +ikvW++ t ++
   Q: 50   HDGPVRGIDFhPTqPLFVSGGDDYKIKVWNYQTRRC 85
           99*********888****************999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ ++f+p+++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++ f+ 
   Q: 3    TKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHPTQPLFVSGGDDYKIKVWNYQTRRCMFTLNGHLDYVRTVFFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllrt 174
           +  +++s s+d+tir+w++++++ +  t +gh++ v+c+++hp+++l++s+slD+ vr+Wd+                               +t+ +++ 
   Q: 104  ELPWILSCSDDQTIRIWNWQNRSLIC-TMTGHNHYVMCAQFHPTEDLIASASLDQSVRIWDIsglrkkhsaptsmsfedqmaranpaqadmfgNTDAVVKF 203
           *************************9.***************************************************************99877777776 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
             +gh++ v+++sf+++ + +vs+++d+ +klw ++ ++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl +++ ++++++  ++++ +a+ 
   Q: 204  VLEGHDRGVNWVSFHPTLPLIVSAGDDRLIKLWRMSDTKAweVDTCRGHFQNASACLFHPHQDLILSVGEDKTIRCWDLNKRTSVQSFKRDLDRFWVIAA- 303
           6777********************************777668**********************************************************. PP
   S: 274  sfgdnvlvlgsedskvniwklkknep 299
           +++ n +++g  d  v+++kl++++p
   Q: 304  HPEINLFAAG-HDTGVMVFKLERERP 328
           5555555444.589*******98775 PP

Organism

Aspergillus niger

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFESKSS RAKGIAFHPK RPWILVSLHS STIQLWDYRM GTLIDRFEEH DGPVRGIDFH 60
PTQPLFVSGG DDYKIKVWNY QTRRCMFTLN GHLDYVRTVF FHHELPWILS CSDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTCACCA AGGTCCGCTA TCCCCTCCCC ATTGCCAGCC CCCCCTATCG CCGCGGAGCT 60
GTTGCTCCTC TCACGAACAG GAACTAATCG TCATCCTCTT TAATAGTTTG AATCCAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	55.57	0.00e+00	986.00
IUUC-Aml-001758	Ailuropoda melanoleuca	49.48	0.00e+00	1232.00
IUUC-Atr-002493	Amborella trichopoda	55.48	0.00e+00	966.00
IUUC-Apl-003385	Anas platyrhynchos	44.72	0.00e+00	926.00
IUUC-Aca-005154	Anolis carolinensis	71.36	1.00e-93	333.00
IUUC-Aly-006020	Arabidopsis lyrata	54.51	0.00e+00	960.00
IUUC-Ath-007360	Arabidopsis thaliana	55.48	0.00e+00	973.00
IUUC-Ago-007992	Ashbya gossypii	53.29	0.00e+00	1274.00
IUUC-Acl-008027	Aspergillus clavatus	92.54	0.00e+00	2241.00
IUUC-Afl-008644	Aspergillus flavus	93.86	0.00e+00	2240.00
IUUC-Afu-008964	Aspergillus fumigatus	93.53	0.00e+00	2294.00
IUUC-Ani-009379	Aspergillus nidulans	90.95	0.00e+00	2219.00
IUUC-Aor-010174	Aspergillus oryzae	93.70	0.00e+00	2237.00
IUUC-Ate-010302	Aspergillus terreus	92.79	0.00e+00	2292.00
IUUC-Ame-011229	Astyanax mexicanus	56.92	0.00e+00	1012.00
IUUC-Bgr-012300	Blumeria graminis	75.86	0.00e+00	1868.00
IUUC-Bta-012524	Bos taurus	49.84	0.00e+00	1226.00
IUUC-Bci-013781	Botrytis cinerea	79.21	0.00e+00	1976.00
IUUC-Bdi-014549	Brachypodium distachyon	47.06	0.00e+00	1149.00
IUUC-Bol-015925	Brassica oleracea	55.60	0.00e+00	969.00
IUUC-Bra-016978	Brassica rapa	55.23	0.00e+00	964.00
IUUC-Cel-018115	Caenorhabditis elegans	52.84	0.00e+00	911.00
IUUC-Cja-019107	Callithrix jacchus	48.35	0.00e+00	1207.00
IUUC-Cfa-020675	Canis familiaris	49.18	0.00e+00	1204.00
IUUC-Cpo-021813	Cavia porcellus	50.00	0.00e+00	1243.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.38	0.00e+00	999.00
IUUC-Csa-023523	Chlorocebus sabaeus	49.84	0.00e+00	1243.00
IUUC-Cho-024704	Choloepus hoffmanni	39.06	8.00e-156	543.00
IUUC-Cin-025572	Ciona intestinalis	48.05	0.00e+00	1190.00
IUUC-Csv-025864	Ciona savignyi	54.76	0.00e+00	950.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	78.29	0.00e+00	1938.00
IUUC-Cne-027053	Cryptococcus neoformans	55.92	0.00e+00	1352.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.92	9.00e-142	496.00
IUUC-Dre-027421	Danio rerio	49.63	0.00e+00	1225.00
IUUC-Dno-029303	Dasypus novemcinctus	49.80	0.00e+00	1243.00
IUUC-Dor-030290	Dipodomys ordii	46.49	3.00e-145	508.00
IUUC-Dse-031543	Dothistroma septosporum	74.47	0.00e+00	1819.00
IUUC-Dme-031945	Drosophila melanogaster	56.62	0.00e+00	972.00
IUUC-Ete-032873	Echinops telfairi	47.89	0.00e+00	1085.00
IUUC-Eca-033773	Equus caballus	48.71	0.00e+00	1196.00
IUUC-Eeu-034874	Erinaceus europaeus	38.58	4.00e-172	597.00
IUUC-Fca-035739	Felis catus	49.19	0.00e+00	1220.00
IUUC-Fal-037263	Ficedula albicollis	46.52	0.00e+00	1101.00
IUUC-Fox-037738	Fusarium oxysporum	76.83	0.00e+00	1966.00
IUUC-Fso-038153	Fusarium solani	77.33	0.00e+00	1959.00
IUUC-Gmo-039602	Gadus morhua	46.68	0.00e+00	1137.00
IUUC-Ggr-039931	Gaeumannomyces graminis	75.54	0.00e+00	1879.00
IUUC-Gga-040590	Gallus gallus	49.40	0.00e+00	1241.00
IUUC-Gac-041318	Gasterosteus aculeatus	48.29	0.00e+00	1217.00
IUUC-Gma-043894	Glycine max	48.29	0.00e+00	1145.00
IUUC-Ggo-045029	Gorilla gorilla	49.48	0.00e+00	1234.00
IUUC-Hsa-046078	Homo sapiens	49.56	0.00e+00	1237.00
IUUC-Hvu-047316	Hordeum vulgare	54.81	0.00e+00	929.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	41.84	0.00e+00	679.00
IUUC-Kpa-049256	Komagataella pastoris	56.53	0.00e+00	1395.00
IUUC-Lch-049706	Latimeria chalumnae	50.00	0.00e+00	1223.00
IUUC-Lpe-051316	Leersia perrieri	55.22	0.00e+00	977.00
IUUC-Loc-051867	Lepisosteus oculatus	39.37	0.00e+00	822.00
IUUC-Lma-053138	Leptosphaeria maculans	84.68	0.00e+00	1543.00
IUUC-Laf-053510	Loxodonta africana	50.12	0.00e+00	1243.00
IUUC-Mcc-055836	Macaca mulatta	49.56	0.00e+00	1239.00
IUUC-Meu-056238	Macropus eugenii	51.62	0.00e+00	703.00
IUUC-Mor-057172	Magnaporthe oryzae	77.08	0.00e+00	1946.00
IUUC-Mpo-057300	Magnaporthe poae	75.02	0.00e+00	1877.00
IUUC-Mtr-058248	Medicago truncatula	47.50	0.00e+00	1147.00
IUUC-Mla-059019	Melampsora laricipopulina	64.20	0.00e+00	1168.00
IUUC-Mga-059499	Meleagris gallopavo	49.40	0.00e+00	1237.00
IUUC-Mvi-060336	Microbotryum violaceum	64.28	0.00e+00	1175.00
IUUC-Mmr-061102	Microcebus murinus	49.48	0.00e+00	1233.00
IUUC-Mdo-062594	Monodelphis domestica	49.92	0.00e+00	1249.00
IUUC-Mmu-063736	Mus musculus	49.56	0.00e+00	1236.00
IUUC-Mac-065272	Musa acuminata	44.35	0.00e+00	1032.00
IUUC-Mpu-066701	Mustela putorius furo	49.08	0.00e+00	1233.00
IUUC-Mlu-067392	Myotis lucifugus	49.32	0.00e+00	1233.00
IUUC-Nfi-068270	Neosartorya fischeri	93.53	0.00e+00	2247.00
IUUC-Ncr-068892	Neurospora crassa	76.12	0.00e+00	1919.00
IUUC-Nle-069634	Nomascus leucogenys	60.15	0.00e+00	870.00
IUUC-Opr-070952	Ochotona princeps	38.50	3.00e-171	594.00
IUUC-Ont-072488	Oreochromis niloticus	48.56	0.00e+00	1209.00
IUUC-Ocu-074211	Oryctolagus cuniculus	49.68	0.00e+00	1237.00
IUUC-Oba-075761	Oryza barthii	54.98	0.00e+00	974.00
IUUC-Obr-076429	Oryza brachyantha	55.10	0.00e+00	978.00
IUUC-Ogl-077364	Oryza glaberrima	54.98	0.00e+00	974.00
IUUC-Ogu-078257	Oryza glumaepatula	54.86	0.00e+00	971.00
IUUC-Oin-080029	Oryza indica	54.98	0.00e+00	976.00
IUUC-Olo-080466	Oryza longistaminata	55.42	0.00e+00	974.00
IUUC-Ome-081993	Oryza meridionalis	57.54	0.00e+00	935.00
IUUC-Oni-082874	Oryza nivara	54.98	0.00e+00	972.00
IUUC-Opu-083885	Oryza punctata	54.98	0.00e+00	974.00
IUUC-Oru-084274	Oryza rufipogon	54.86	0.00e+00	972.00
IUUC-Osa-085565	Oryza sativa	54.86	0.00e+00	972.00
IUUC-Ola-086921	Oryzias latipes	48.87	0.00e+00	1205.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.71	0.00e+00	1181.00
IUUC-Oga-087991	Otolemur garnettii	47.02	0.00e+00	1159.00
IUUC-Oar-089590	Ovis aries	49.84	0.00e+00	1240.00
IUUC-Ptr-090808	Pan troglodytes	49.48	0.00e+00	1235.00
IUUC-Pan-092475	Papio anubis	49.64	0.00e+00	1231.00
IUUC-Psi-093044	Pelodiscus sinensis	51.25	0.00e+00	849.00
IUUC-Pno-094839	Phaeosphaeria nodorum	75.23	0.00e+00	1818.00
IUUC-Ppa-095254	Physcomitrella patens	50.28	0.00e+00	1226.00
IUUC-Pfo-097493	Poecilia formosa	49.19	0.00e+00	1212.00
IUUC-Pab-098497	Pongo abelii	49.76	0.00e+00	1243.00
IUUC-Pop-099992	Populus trichocarpa	55.77	0.00e+00	969.00
IUUC-Pca-100413	Procavia capensis	53.41	4.00e-179	620.00
IUUC-Ppe-101899	Prunus persica	47.73	0.00e+00	1129.00
IUUC-Pva-102126	Pteropus vampyrus	47.86	0.00e+00	1175.00
IUUC-Pgr-103376	Puccinia graminis	56.54	0.00e+00	1434.00
IUUC-Ptt-103978	Puccinia triticina	51.30	0.00e+00	1220.00
IUUC-Pte-104126	Pyrenophora teres	83.68	0.00e+00	1486.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	74.86	0.00e+00	1070.00
IUUC-Rno-105428	Rattus norvegicus	50.16	0.00e+00	1246.00
IUUC-Sce-106464	Saccharomyces cerevisiae	53.39	0.00e+00	1270.00
IUUC-Sha-107301	Sarcophilus harrisii	49.92	0.00e+00	1221.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.21	0.00e+00	1321.00
IUUC-Spo-108217	Schizosaccharomyces pombe	55.16	0.00e+00	1384.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	79.11	0.00e+00	1971.00
IUUC-Smo-109582	Selaginella moellendorffii	56.84	0.00e+00	1014.00
IUUC-Sit-109697	Setaria italica	55.10	0.00e+00	976.00
IUUC-Sly-111447	Solanum lycopersicum	46.35	0.00e+00	1135.00
IUUC-Stu-112564	Solanum tuberosum	46.06	0.00e+00	1137.00
IUUC-Sar-113313	Sorex araneus	41.51	5.00e-167	579.00
IUUC-Sbi-114388	Sorghum bicolor	55.10	0.00e+00	976.00
IUUC-Sre-115209	Sporisorium reilianum	61.85	0.00e+00	1117.00
IUUC-Ssc-115933	Sus scrofa	49.76	0.00e+00	1239.00
IUUC-Tgu-117109	Taeniopygia guttata	43.77	5.00e-92	329.00
IUUC-Tru-117772	Takifugu rubripes	47.82	0.00e+00	1191.00
IUUC-Tsy-119105	Tarsius syrichta	47.51	0.00e+00	934.00
IUUC-Tni-120556	Tetraodon nigroviridis	37.99	0.00e+00	795.00
IUUC-Tca-121046	Theobroma cacao	47.85	0.00e+00	1144.00
IUUC-Tre-121951	Trichoderma reesei	75.53	0.00e+00	1889.00
IUUC-Tvi-122359	Trichoderma virens	75.39	0.00e+00	1915.00
IUUC-Tae-123611	Triticum aestivum	55.57	0.00e+00	985.00
IUUC-Tur-126754	Triticum urartu	48.03	0.00e+00	1145.00
IUUC-Tme-127170	Tuber melanosporum	76.92	0.00e+00	1956.00
IUUC-Tbe-127882	Tupaia belangeri	61.86	8.00e-121	426.00
IUUC-Ttr-128217	Tursiops truncatus	47.86	0.00e+00	1169.00
IUUC-Uma-129337	Ustilago maydis	61.26	0.00e+00	1105.00
IUUC-Vda-129828	Verticillium dahliae	74.50	0.00e+00	1887.00
IUUC-Vpa-130537	Vicugna pacos	49.23	0.00e+00	1222.00
IUUC-Vvi-130958	Vitis vinifera	56.08	0.00e+00	986.00
IUUC-Xtr-132857	Xenopus tropicalis	48.45	0.00e+00	1151.00
IUUC-Xma-133138	Xiphophorus maculatus	49.51	0.00e+00	1214.00
IUUC-Yli-134399	Yarrowia lipolytica	59.95	0.00e+00	1069.00
IUUC-Zma-135612	Zea mays	46.26	0.00e+00	1133.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence