iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-009055

Ensembl Protein ID

CADAFUAP00006709

UniProt Accession

Q4WVM1; RAD5_ASPFU

Genbank Protein ID

EAL91355.1

Protein Name

DNA repair protein rad5

Genbank Nucleotide ID

AAHF01000003

Gene Name

AFUA_5G12600; rad5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00006709	CADAFUAT00006709	CADAFUAP00006709

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	31.17	7.00e-132	469.00	IUUC-Ath-007517
E3 activity/RING/RING	33.59	8.00e-143	503.00	IUUC-Sce-106396
E3 activity/RING/RING	36.17	0.00e+00	667.00	IUUC-Spo-108026

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Aspergillus fumigatus

Functional Description
(View)

Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

Protein Sequence
(Fasta)

MTSARPKCGG SSRRSPSRRV SRPSMIRRIE FDAFCARSLT FPCHKFGHLI SGKTFKMVFG 60
DLNERPLKKR RFFVDEEDTH PPSSEAAPVT TNLDTSTISS AGPEGSDVRQ QQLNGAVPFP 120

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Nucleotide Sequence
(Fasta)

ATGACGTCGG CCCGCCCGAA GTGCGGTGGT TCATCGCGTC GTTCTCCGTC TCGGCGCGTC 60
TCCCGTCCAT CAATGATCAG GCGCATCGAA TTCGATGCCT TTTGTGCTCG TTCTCTAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair

KEGG

afm:AFUA_5G12600

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	32.45	5.00e-132	463.00
IUUC-Atr-003139	Amborella trichopoda	31.92	2.00e-133	468.00
IUUC-Aly-006331	Arabidopsis lyrata	32.66	2.00e-133	468.00
IUUC-Ath-007517	Arabidopsis thaliana	33.03	3.00e-133	468.00
IUUC-Ago-007997	Ashbya gossypii	32.16	8.00e-136	476.00
IUUC-Acl-008022	Aspergillus clavatus	77.96	0.00e+00	1857.00
IUUC-Afl-008514	Aspergillus flavus	70.90	0.00e+00	1705.00
IUUC-Ani-009340	Aspergillus nidulans	66.40	0.00e+00	1477.00
IUUC-Ang-009785	Aspergillus niger	68.74	0.00e+00	1650.00
IUUC-Aor-010158	Aspergillus oryzae	70.98	0.00e+00	1706.00
IUUC-Ate-010536	Aspergillus terreus	69.54	0.00e+00	1570.00
IUUC-Bgr-012147	Blumeria graminis	52.41	0.00e+00	1070.00
IUUC-Bci-013741	Botrytis cinerea	56.88	0.00e+00	1161.00
IUUC-Bdi-014496	Brachypodium distachyon	32.91	4.00e-132	464.00
IUUC-Bol-015995	Brassica oleracea	33.57	3.00e-137	481.00
IUUC-Bra-017004	Brassica rapa	36.95	9.00e-133	466.00
IUUC-Cho-024891	Choloepus hoffmanni	30.47	7.00e-54	204.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	55.14	0.00e+00	1122.00
IUUC-Cne-026886	Cryptococcus neoformans	34.61	2.00e-160	558.00
IUUC-Cme-027110	Cyanidioschyzon merolae	32.10	3.00e-91	328.00
IUUC-Dse-031471	Dothistroma septosporum	54.87	0.00e+00	1169.00
IUUC-Ete-032421	Echinops telfairi	28.34	2.00e-59	222.00
IUUC-Fox-038039	Fusarium oxysporum	54.92	0.00e+00	1130.00
IUUC-Fso-038179	Fusarium solani	55.94	0.00e+00	1130.00
IUUC-Gmo-038544	Gadus morhua	31.62	7.00e-85	306.00
IUUC-Ggr-039735	Gaeumannomyces graminis	55.08	0.00e+00	1125.00
IUUC-Gma-042995	Glycine max	30.99	2.00e-130	458.00
IUUC-Hvu-047747	Hordeum vulgare	32.45	8.00e-133	466.00
IUUC-Kpa-049087	Komagataella pastoris	32.22	2.00e-139	488.00
IUUC-Lpe-051123	Leersia perrieri	32.67	5.00e-135	473.00
IUUC-Lma-052956	Leptosphaeria maculans	54.31	0.00e+00	1140.00
IUUC-Mor-057210	Magnaporthe oryzae	54.36	0.00e+00	1117.00
IUUC-Mpo-057407	Magnaporthe poae	54.80	0.00e+00	1121.00
IUUC-Mtr-058565	Medicago truncatula	32.72	9.00e-131	459.00
IUUC-Mla-058867	Melampsora laricipopulina	30.42	2.00e-90	325.00
IUUC-Mvi-060322	Microbotryum violaceum	36.21	5.00e-131	460.00
IUUC-Mac-064548	Musa acuminata	31.70	1.00e-123	435.00
IUUC-Nfi-068354	Neosartorya fischeri	95.20	0.00e+00	2304.00
IUUC-Ncr-068844	Neurospora crassa	55.54	0.00e+00	1155.00
IUUC-Ont-071782	Oreochromis niloticus	30.16	3.00e-83	301.00
IUUC-Oba-075316	Oryza barthii	32.12	1.00e-127	449.00
IUUC-Obr-076834	Oryza brachyantha	33.30	1.00e-137	482.00
IUUC-Ogl-077508	Oryza glaberrima	32.94	3.00e-132	464.00
IUUC-Ogu-078083	Oryza glumaepatula	32.31	9.00e-134	469.00
IUUC-Oin-079893	Oryza indica	33.14	3.00e-137	481.00
IUUC-Olo-080615	Oryza longistaminata	33.30	4.00e-138	484.00
IUUC-Ome-081448	Oryza meridionalis	31.17	3.00e-112	398.00
IUUC-Oni-082773	Oryza nivara	32.31	4.00e-133	467.00
IUUC-Opu-083675	Oryza punctata	33.10	2.00e-136	478.00
IUUC-Oru-084543	Oryza rufipogon	32.31	3.00e-132	464.00
IUUC-Osa-085686	Oryza sativa	34.87	4.00e-119	420.00
IUUC-Pno-094916	Phaeosphaeria nodorum	54.42	0.00e+00	1130.00
IUUC-Ppa-095877	Physcomitrella patens	36.33	4.00e-132	464.00
IUUC-Pop-099320	Populus trichocarpa	32.15	2.00e-130	458.00
IUUC-Ppe-101820	Prunus persica	31.06	1.00e-134	472.00
IUUC-Pgr-103454	Puccinia graminis	30.96	1.00e-131	462.00
IUUC-Ptt-103829	Puccinia triticina	32.56	2.00e-95	342.00
IUUC-Pte-104242	Pyrenophora teres	53.15	0.00e+00	1140.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	57.74	0.00e+00	1121.00
IUUC-Sce-106396	Saccharomyces cerevisiae	35.78	2.00e-130	459.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	38.02	0.00e+00	684.00
IUUC-Spo-108026	Schizosaccharomyces pombe	36.13	0.00e+00	668.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	57.13	0.00e+00	1170.00
IUUC-Smo-109311	Selaginella moellendorffii	31.41	2.00e-91	328.00
IUUC-Sit-110076	Setaria italica	31.73	6.00e-126	443.00
IUUC-Sly-111908	Solanum lycopersicum	31.68	2.00e-132	465.00
IUUC-Stu-112600	Solanum tuberosum	32.11	4.00e-128	451.00
IUUC-Sbi-113927	Sorghum bicolor	31.18	2.00e-125	442.00
IUUC-Sre-115131	Sporisorium reilianum	37.79	5.00e-151	527.00
IUUC-Tru-117768	Takifugu rubripes	31.60	1.00e-78	286.00
IUUC-Tca-121137	Theobroma cacao	32.32	4.00e-132	464.00
IUUC-Tre-121896	Trichoderma reesei	54.38	0.00e+00	1106.00
IUUC-Tvi-122597	Trichoderma virens	55.37	0.00e+00	1147.00
IUUC-Tae-125036	Triticum aestivum	33.14	4.00e-134	471.00
IUUC-Tur-125999	Triticum urartu	36.39	1.00e-129	456.00
IUUC-Tme-126953	Tuber melanosporum	46.67	0.00e+00	927.00
IUUC-Uma-129629	Ustilago maydis	34.41	4.00e-165	573.00
IUUC-Vda-129849	Verticillium dahliae	53.00	0.00e+00	1065.00
IUUC-Vvi-130943	Vitis vinifera	32.01	8.00e-132	462.00
IUUC-Yli-134588	Yarrowia lipolytica	34.81	2.00e-169	588.00
IUUC-Zma-135801	Zea mays	31.15	2.00e-120	425.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence