iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-20	73.0	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++++++s D+++k WD+r+ 
   Q: 190  HLSKIHGLDWhPDseHIFATSSQDNSVKFWDYRQP 224
           99*********6665778*************9876 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDSQAT AMSVDCVGQH AVLSGRRFLY IVNLDAPFEG HRKISRQSKW 60
DIGAVQWNPH DSFAHYFAAS SNQRVDLYKW KDGSGEVGTT LQGHTRVISD LDWAVFEPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAACAGAA GAGGCGGGAT CTATCATCGG AGTAGCCAAT GCGTTGCGGT CAAGTGAAAG 60
GCAGGGAACG AGGCGTGGCC GGATTTATTA GCTGGCTGTG TGGGGCTTAC TAACCTAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	91.31	0.00e+00	1704.00
IUUC-Apl-004021	Anas platyrhynchos	83.61	0.00e+00	1503.00
IUUC-Aca-004977	Anolis carolinensis	83.39	0.00e+00	1573.00
IUUC-Ago-007961	Ashbya gossypii	25.17	1.00e-60	228.00
IUUC-Acl-008161	Aspergillus clavatus	27.77	1.00e-54	209.00
IUUC-Afl-008686	Aspergillus flavus	28.39	6.00e-57	216.00
IUUC-Afu-008932	Aspergillus fumigatus	28.31	3.00e-56	214.00
IUUC-Ani-009493	Aspergillus nidulans	28.13	1.00e-59	225.00
IUUC-Ang-009876	Aspergillus niger	28.52	2.00e-57	218.00
IUUC-Aor-009926	Aspergillus oryzae	28.39	7.00e-57	216.00
IUUC-Ate-010274	Aspergillus terreus	34.06	2.00e-50	195.00
IUUC-Ame-011297	Astyanax mexicanus	70.10	0.00e+00	1265.00
IUUC-Bgr-012173	Blumeria graminis	31.56	2.00e-43	172.00
IUUC-Bta-013261	Bos taurus	92.27	0.00e+00	1728.00
IUUC-Bci-013971	Botrytis cinerea	32.72	1.00e-46	182.00
IUUC-Cja-019167	Callithrix jacchus	90.99	0.00e+00	1701.00
IUUC-Cfa-020287	Canis familiaris	91.52	0.00e+00	1705.00
IUUC-Cpo-022510	Cavia porcellus	89.55	0.00e+00	1618.00
IUUC-Csa-023474	Chlorocebus sabaeus	94.85	0.00e+00	1795.00
IUUC-Cho-024634	Choloepus hoffmanni	90.12	0.00e+00	768.00
IUUC-Cin-025642	Ciona intestinalis	32.70	4.00e-122	432.00
IUUC-Csv-025848	Ciona savignyi	44.17	6.00e-54	203.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.80	2.00e-44	174.00
IUUC-Cne-027088	Cryptococcus neoformans	32.01	3.00e-43	171.00
IUUC-Dre-028753	Danio rerio	68.65	0.00e+00	1222.00
IUUC-Dno-029733	Dasypus novemcinctus	89.78	0.00e+00	1674.00
IUUC-Dor-030781	Dipodomys ordii	91.34	0.00e+00	805.00
IUUC-Dme-031803	Drosophila melanogaster	33.33	2.00e-127	450.00
IUUC-Ete-032622	Echinops telfairi	82.19	0.00e+00	1496.00
IUUC-Eca-033344	Equus caballus	91.95	0.00e+00	1705.00
IUUC-Eeu-034523	Erinaceus europaeus	81.73	0.00e+00	1465.00
IUUC-Fca-035650	Felis catus	92.38	0.00e+00	1728.00
IUUC-Fal-037404	Ficedula albicollis	83.28	0.00e+00	1521.00
IUUC-Fox-037955	Fusarium oxysporum	34.18	2.00e-42	168.00
IUUC-Fso-038289	Fusarium solani	33.54	8.00e-47	183.00
IUUC-Gmo-038547	Gadus morhua	68.32	0.00e+00	1270.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.50	7.00e-43	170.00
IUUC-Gga-041030	Gallus gallus	83.91	0.00e+00	1537.00
IUUC-Gac-042581	Gasterosteus aculeatus	70.72	0.00e+00	1305.00
IUUC-Ggo-044641	Gorilla gorilla	92.27	0.00e+00	1727.00
IUUC-Hsa-046134	Homo sapiens	92.60	0.00e+00	1730.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	94.41	0.00e+00	739.00
IUUC-Kpa-049091	Komagataella pastoris	33.85	1.00e-45	179.00
IUUC-Lch-050288	Latimeria chalumnae	71.17	0.00e+00	1285.00
IUUC-Loc-052802	Lepisosteus oculatus	73.17	0.00e+00	1364.00
IUUC-Lma-053296	Leptosphaeria maculans	32.92	4.00e-48	187.00
IUUC-Laf-053997	Loxodonta africana	94.53	0.00e+00	1800.00
IUUC-Mcc-055855	Macaca mulatta	92.38	0.00e+00	1715.00
IUUC-Meu-056898	Macropus eugenii	85.01	1.00e-156	547.00
IUUC-Mor-056913	Magnaporthe oryzae	35.36	2.00e-42	169.00
IUUC-Mpo-057612	Magnaporthe poae	36.86	1.00e-43	171.00
IUUC-Mla-059097	Melampsora laricipopulina	31.85	3.00e-47	184.00
IUUC-Mga-059218	Meleagris gallopavo	83.61	0.00e+00	1500.00
IUUC-Mvi-060251	Microbotryum violaceum	30.98	8.00e-46	179.00
IUUC-Mmr-061093	Microcebus murinus	89.16	0.00e+00	1648.00
IUUC-Mdo-062757	Monodelphis domestica	87.35	0.00e+00	1621.00
IUUC-Mmu-063839	Mus musculus	97.21	0.00e+00	1842.00
IUUC-Mpu-065977	Mustela putorius furo	92.06	0.00e+00	1719.00
IUUC-Mlu-067460	Myotis lucifugus	90.34	0.00e+00	1715.00
IUUC-Nfi-068250	Neosartorya fischeri	27.93	2.00e-56	214.00
IUUC-Ncr-068710	Neurospora crassa	32.72	2.00e-45	178.00
IUUC-Nle-070011	Nomascus leucogenys	92.17	0.00e+00	1722.00
IUUC-Opr-070731	Ochotona princeps	90.48	0.00e+00	1086.00
IUUC-Ont-072165	Oreochromis niloticus	67.80	0.00e+00	1254.00
IUUC-Oan-072887	Ornithorhynchus anatinus	90.80	0.00e+00	1714.00
IUUC-Ocu-073926	Oryctolagus cuniculus	95.56	0.00e+00	1795.00
IUUC-Ola-087111	Oryzias latipes	66.77	0.00e+00	1228.00
IUUC-Oga-088850	Otolemur garnettii	92.27	0.00e+00	1719.00
IUUC-Oar-090291	Ovis aries	91.95	0.00e+00	1722.00
IUUC-Ptr-091044	Pan troglodytes	92.27	0.00e+00	1719.00
IUUC-Pan-092374	Papio anubis	94.64	0.00e+00	1790.00
IUUC-Psi-093170	Pelodiscus sinensis	51.78	0.00e+00	814.00
IUUC-Pma-094544	Petromyzon marinus	66.52	1.00e-170	592.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.93	6.00e-44	173.00
IUUC-Pfo-096480	Poecilia formosa	67.26	0.00e+00	1207.00
IUUC-Pab-098134	Pongo abelii	91.06	0.00e+00	1681.00
IUUC-Pca-100763	Procavia capensis	70.75	0.00e+00	963.00
IUUC-Pva-102544	Pteropus vampyrus	91.09	0.00e+00	1716.00
IUUC-Pgr-103257	Puccinia graminis	32.21	7.00e-50	193.00
IUUC-Ptt-103942	Puccinia triticina	31.41	2.00e-45	177.00
IUUC-Pte-104065	Pyrenophora teres	32.20	1.00e-45	179.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.52	1.00e-56	215.00
IUUC-Sha-106662	Sarcophilus harrisii	89.86	0.00e+00	1647.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.29	5.00e-69	256.00
IUUC-Spo-108265	Schizosaccharomyces pombe	26.47	6.00e-68	253.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.43	6.00e-46	180.00
IUUC-Sar-113525	Sorex araneus	87.80	0.00e+00	1055.00
IUUC-Sre-115163	Sporisorium reilianum	36.43	3.00e-40	160.00
IUUC-Ssc-115381	Sus scrofa	90.65	0.00e+00	863.00
IUUC-Tgu-116525	Taeniopygia guttata	79.85	0.00e+00	1457.00
IUUC-Tru-118432	Takifugu rubripes	68.14	0.00e+00	1274.00
IUUC-Tsy-119306	Tarsius syrichta	81.11	0.00e+00	936.00
IUUC-Tni-120757	Tetraodon nigroviridis	68.64	0.00e+00	1251.00
IUUC-Tre-122187	Trichoderma reesei	35.05	2.00e-47	184.00
IUUC-Tvi-122367	Trichoderma virens	35.37	4.00e-47	184.00
IUUC-Tme-126986	Tuber melanosporum	29.44	9.00e-61	229.00
IUUC-Tbe-127800	Tupaia belangeri	78.47	0.00e+00	1346.00
IUUC-Ttr-129154	Tursiops truncatus	88.55	0.00e+00	1011.00
IUUC-Uma-129366	Ustilago maydis	35.97	2.00e-39	158.00
IUUC-Vda-129827	Verticillium dahliae	33.65	8.00e-47	183.00
IUUC-Vpa-130493	Vicugna pacos	91.68	0.00e+00	1667.00
IUUC-Xtr-131941	Xenopus tropicalis	77.81	0.00e+00	1421.00
IUUC-Xma-133903	Xiphophorus maculatus	65.99	0.00e+00	1231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence