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Tag Content
UUCD2 ID IUUC-Cja-019144
UUCD1 version UUC-CaJ-01121
Ensembl Protein ID ENSCJAP00000002443.2
UniProt Accession F7I004; F7I004_CALJA
Genbank Protein ID JAB26147.1; JAB46389.1
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ACFV01010508; GAMP01006366
Gene Name USP45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000001356.2 ENSCJAT00000002536.2 ENSCJAP00000002406.2
ENSCJAG00000001356.2 ENSCJAT00000002570.2 ENSCJAP00000002435.2
ENSCJAG00000001356.2 ENSCJAT00000002579.2 ENSCJAP00000002443.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.20e-85 286.9 191 813
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenp..............kepkgellkslqklfeelwkskkkavsprell 74
           Gl+NlgNtC++N+v+Q L+++  l++l++e  +  ++++  +                ++ g+l+++l  +++++ +++k+  sp+ l+
   Q: 191  GLTNLGNTCFFNAVMQNLAQTYILTDLMNEikE--NSTKL-KIfpssdsqldplvveLSRPGPLTSALFLFLHSMKETEKGPLSPKVLF 276
           9*****************************442..33222.223456666666777777777*************************** PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk......slisdlFqgqlksqikcl 157
           ++l+++a++f+ ++qqD+qE+l++lld++++e +k+ + ++ +++++ ++++ d++ +kk k +       ++i+++F g+l+s+++c+
   Q: 277  NQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKIKAYGkegvkmNFIDRIFIGELTSTVMCE 365
           *********************************99888888888888877777775555544444455555****************** PP
   S: 158  ecdnvssreepfldlslpvpgkeetkke............................................................. 185
           ec+n+s  ++pf+d+slp+ +++ +k++                                                             
   Q: 366  ECANISMVKDPFIDISLPIIEERVSKPLlvgrmnkyrslqetdhdrcsgsvaienipqpraakkhsspkdknqlihdrkrikklssget 454
           ***********************99888************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 455  vviyqknenlemnedslmfaslmnsesplnesptddsekeashsesnvdadseasesegaskqpglfrsssgsgvhtdgplyppsagem 543
           ***************************************************************************************** PP
   S: 186  ............................................................................slqdcLesftkee 198
                                                                                       s+q+cL +ft+ e
   Q: 544  lytketdsgdkemseaiselslsstvtgdqdfvrenqplnisnnlcfsegkhlrsqspqnafqtlsqsyitaskecSVQSCLYQFTSME 632
           ***************************************************************************************** PP
   S: 199  elegenkyycekckkkqe...................aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
            l g+nk+ ce+c+++++                   a+k+l ++ +P vLilhLkRf  ++++ s +k+n++v+fpl+Ldl+pfc+ +
   Q: 633  LLIGNNKLLCENCTENKQkyqeetslaekkvegvytnARKQLLISAIPVVLILHLKRF--HQAGLSLRKVNRHVDFPLTLDLAPFCSAT 719
           **************87777888888888888999999*********************..9999************************8 PP
   S: 269  eekqke..kkkYeLiavvvHsGslssGHYvayvkn..........................ekgkWllfdDskVtevkeeevleetgst 329
           +++ +   k+ Y L+++v HsGs+++GHY+ayv+                           + g+W++++D++V++v+e++ l+   ++
   Q: 720  CKNASMgdKVLYGLYGIVEHSGSMRGGHYTAYVRVrtpsrkltehitkkknvpglkeadseSAGQWVHVSDTYVQAVPESRALS---AQ 805
           877655669**************************999999999999999999999888877888*******************...** PP
   S: 330  aYvlfYkr 337
           aY+lfY+r
   Q: 806  AYLLFYER 813
           ******98 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MRVKDPTKAL PEKGKRSKRP TVPHDEDSSD DIAVGLTCQH VSHAISVNHV KRAIAENLWS 60
VCSECLKERR FCDGQPVLPS DTWLCLKCGF QGCGKNSESQ HSLKHFKSSG TEPHCIIISL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-019144|DUB,USP|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCTGTGGT CGCAGCGGCA GTACGATCGC CGCAGTTTCT CGGTCTTCGC TTCAGCGACC 60
TTGGTCCCTG TGGGTGGGCA AAGCTGGGAG AGAGGCTTCC TACCCTCCTT GGCTTCCAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-019144|DUB,USP|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cjc:100394353
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002331 Ailuropoda melanoleuca 72.66 0.00e+00 1100.00
IUUC-Apl-003512 Anas platyrhynchos 68.04 0.00e+00 1082.00
IUUC-Aca-004284 Anolis carolinensis 59.40 0.00e+00 976.00
IUUC-Ame-010735 Astyanax mexicanus 65.11 2.00e-87 315.00
IUUC-Bta-012880 Bos taurus 81.30 0.00e+00 1283.00
IUUC-Cfa-020971 Canis familiaris 81.59 0.00e+00 734.00
IUUC-Cpo-022497 Cavia porcellus 68.57 0.00e+00 1073.00
IUUC-Csa-023910 Chlorocebus sabaeus 91.19 0.00e+00 1408.00
IUUC-Cho-024358 Choloepus hoffmanni 60.92 4.00e-111 395.00
IUUC-Dre-028106 Danio rerio 59.71 2.00e-147 516.00
IUUC-Dno-029456 Dasypus novemcinctus 76.33 0.00e+00 728.00
IUUC-Dor-030438 Dipodomys ordii 63.28 0.00e+00 954.00
IUUC-Dme-031870 Drosophila melanogaster 47.31 4.00e-36 147.00
IUUC-Ete-032736 Echinops telfairi 64.81 0.00e+00 961.00
IUUC-Eca-034211 Equus caballus 82.05 0.00e+00 1338.00
IUUC-Eeu-034797 Erinaceus europaeus 77.39 3.00e-87 316.00
IUUC-Fca-035947 Felis catus 78.14 0.00e+00 1161.00
IUUC-Fal-037199 Ficedula albicollis 67.12 0.00e+00 936.00
IUUC-Gmo-039228 Gadus morhua 60.25 2.00e-140 493.00
IUUC-Gga-040823 Gallus gallus 63.60 2.00e-171 595.00
IUUC-Gac-042406 Gasterosteus aculeatus 59.46 1.00e-135 477.00
IUUC-Ggo-045402 Gorilla gorilla 92.77 0.00e+00 1513.00
IUUC-Hsa-046430 Homo sapiens 92.64 0.00e+00 1514.00
IUUC-Itr-048855 Ictidomys tridecemlineatus 80.87 0.00e+00 773.00
IUUC-Lch-049547 Latimeria chalumnae 58.70 0.00e+00 924.00
IUUC-Loc-052842 Lepisosteus oculatus 55.86 0.00e+00 895.00
IUUC-Laf-053988 Loxodonta africana 82.56 0.00e+00 1355.00
IUUC-Mcc-055491 Macaca mulatta 87.25 0.00e+00 1417.00
IUUC-Meu-056256 Macropus eugenii 63.89 2.00e-179 622.00
IUUC-Mtr-057945 Medicago truncatula 30.96 5.00e-32 133.00
IUUC-Mla-059026 Melampsora laricipopulina 31.22 3.00e-17 83.60
IUUC-Mga-059833 Meleagris gallopavo 60.65 3.00e-174 605.00
IUUC-Mmr-060952 Microcebus murinus 84.70 0.00e+00 1354.00
IUUC-Mdo-062642 Monodelphis domestica 69.37 0.00e+00 1091.00
IUUC-Mmu-063945 Mus musculus 78.24 0.00e+00 1266.00
IUUC-Mpu-065944 Mustela putorius furo 75.67 0.00e+00 1182.00
IUUC-Mlu-067049 Myotis lucifugus 81.22 0.00e+00 1269.00
IUUC-Nle-069828 Nomascus leucogenys 92.28 0.00e+00 1514.00
IUUC-Opr-070672 Ochotona princeps 71.54 1.00e-144 506.00
IUUC-Ont-072121 Oreochromis niloticus 59.12 3.00e-134 472.00
IUUC-Oan-073656 Ornithorhynchus anatinus 64.05 0.00e+00 1040.00
IUUC-Ocu-074323 Oryctolagus cuniculus 80.81 0.00e+00 1271.00
IUUC-Ola-087238 Oryzias latipes 53.20 0.00e+00 801.00
IUUC-Oga-088379 Otolemur garnettii 78.09 0.00e+00 1264.00
IUUC-Oar-089718 Ovis aries 81.17 0.00e+00 1284.00
IUUC-Ptr-091358 Pan troglodytes 92.64 0.00e+00 1515.00
IUUC-Pan-092023 Papio anubis 92.16 0.00e+00 1506.00
IUUC-Psi-093256 Pelodiscus sinensis 66.06 0.00e+00 1000.00
IUUC-Ppa-095584 Physcomitrella patens 27.95 9.00e-36 145.00
IUUC-Pfo-097285 Poecilia formosa 48.67 0.00e+00 703.00
IUUC-Pab-098539 Pongo abelii 92.88 0.00e+00 1518.00
IUUC-Pca-100610 Procavia capensis 66.80 0.00e+00 931.00
IUUC-Pva-102985 Pteropus vampyrus 90.54 0.00e+00 705.00
IUUC-Rno-105538 Rattus norvegicus 76.16 0.00e+00 1259.00
IUUC-Sha-107022 Sarcophilus harrisii 60.65 0.00e+00 966.00
IUUC-Sja-107712 Schizosaccharomyces japonicus 27.92 3.00e-20 94.00
IUUC-Spo-108149 Schizosaccharomyces pombe 30.66 1.00e-20 95.10
IUUC-Sar-113637 Sorex araneus 70.90 0.00e+00 1082.00
IUUC-Ssc-115870 Sus scrofa 80.93 0.00e+00 1324.00
IUUC-Tgu-116907 Taeniopygia guttata 67.68 0.00e+00 1075.00
IUUC-Tru-117835 Takifugu rubripes 51.63 5.00e-107 382.00
IUUC-Tsy-118869 Tarsius syrichta 84.39 0.00e+00 1217.00
IUUC-Tni-119716 Tetraodon nigroviridis 63.41 2.00e-92 333.00
IUUC-Tbe-128041 Tupaia belangeri 65.40 0.00e+00 957.00
IUUC-Ttr-128901 Tursiops truncatus 80.66 0.00e+00 1301.00
IUUC-Vpa-130331 Vicugna pacos 82.41 0.00e+00 1214.00
IUUC-Xtr-131794 Xenopus tropicalis 52.36 0.00e+00 766.00
Created Date 25-Jun-2017

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