iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004714

UUCD1 version

UUC-AnC-00910

Ensembl Protein ID

ENSACAP00000020635.1

UniProt Accession

H9GUD0; H9GUD0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000027391.1	ENSACAT00000022829.1	ENSACAP00000020635.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.30e-52	175.5	2	128

Active Site

Position(s)	Description	Evidence
74	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 9    lekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspals 97
           l++dpp+g+s  p+++ +++ w+++i+Gpe+tp+e+g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  ++Wsp+++
   Q: 2    LQEDPPAGVSGAPSEN-NIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ--NRWSPTYD 87
           89*************9.9************************************************************9..******** PP
   S: 98   vesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 88   VSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 128
           **************************************996 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

RLQEDPPAGV SGAPSENNIM VWNAVIFGPE GTPFEDGTFK LTIEFTEEYP NKPPTVRFVS 60
KMFHPNVYAD GSICLDILQN RWSPTYDVSS ILTSIQSLLD EPNPNSPANS QAAQLYQENK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTGCAGG AAGACCCTCC AGCTGGAGTT AGCGGCGCCC CTTCGGAGAA TAACATCATG 60
GTCTGGAATG CCGTCATTTT CGGGTGAGGA AAAGGCCTAC ATTAGGCAAA CACTGGTCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0016574--P:histone ubiquitination
GO:0008284--P:positive regulation of cell proliferation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bgr-012039	Blumeria graminis	66.91	2.00e-56	210.00
IUUC-Cho-025061	Choloepus hoffmanni	98.18	7.00e-60	221.00
IUUC-Fal-037474	Ficedula albicollis	100.00	1.00e-68	250.00
IUUC-Mor-057087	Magnaporthe oryzae	67.16	2.00e-54	204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence