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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063239
UUCD1 version UUC-MuM-00049
Ensembl Protein ID ENSMUSP00000018877.2
UniProt Accession Q8VC48; PEX12_MOUSE
Genbank Protein ID AAH21800.1
Protein Name Peroxisome assembly protein 12; Peroxin-12
Genbank Nucleotide ID BC021800
Gene Name Pex12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000018733.10 ENSMUST00000018877.8 ENSMUSP00000018877.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 19687296
Classification
Family E-value Score Start End
E3 activity/RING/RING 0.98 11.1 304 341
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C+    + +++   g vf+  C+ ++       + ++ CP+
   Q: 304  CPLCRKTRVNDTVLATSGYVFCYRCVFNY------VRSHQACPI 341
           ****9966444888999*********999......899999996 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Interacts with PEX5 and PEX10. Interacts with PEX19 via its cytoplasmic domain (By similarity).
 Interacts with PEX5 and PEX10. Interacts with PEX19 via its cytoplasmic domain (By similarity).
Protein Sequence
(Fasta)
MAEYGAHITT ASVADDQPSI FEVVAQDSLM TAVRPALQHV VKVLAESNPA HYGFLWRWFD 60
EIFTLLDFLL QQHYLSRTSA SFSEHFYGLK RIVAGSSPHL QRPASAGLPK EHLWKSAMFL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063239|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCTGTCTCA GGGATAGGGC AGTTGCCTAT ACACTCAGGA GACCCGCAGT TGCTTTCCCA 60
CCGGATATCT TCAATAAGTG GGTATTTTCG GGATTTATTC CCGTGAACAA GATTTTTGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063239|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0576--Peroxisome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR017375--PEX12
IPR006845--Pex_N
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF04757--Pex2_Pex12
Gene Ontology

GO:0005779--C:integral component of peroxisomal membrane
GO:1990429--C:peroxisomal importomer complex
GO:0005778--C:peroxisomal membrane
GO:0005777--C:peroxisome
GO:0008022--F:protein C-terminus binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007031--P:peroxisome organization
GO:0016558--P:protein import into peroxisome matrix
GO:0006513--P:protein monoubiquitination
KEGG mmu:103737
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001074 Aegilops tauschii 42.06 1.00e-18 87.40
IUUC-Aml-001787 Ailuropoda melanoleuca 88.02 5.00e-156 543.00
IUUC-Atr-002774 Amborella trichopoda 33.25 1.00e-42 167.00
IUUC-Apl-003884 Anas platyrhynchos 67.49 1.00e-100 359.00
IUUC-Aly-005467 Arabidopsis lyrata 29.02 2.00e-32 133.00
IUUC-Ath-007043 Arabidopsis thaliana 29.53 4.00e-32 132.00
IUUC-Ago-007833 Ashbya gossypii 26.89 9.00e-13 67.80
IUUC-Acl-008074 Aspergillus clavatus 25.06 3.00e-25 109.00
IUUC-Afl-008656 Aspergillus flavus 27.72 9.00e-22 98.20
IUUC-Afu-008808 Aspergillus fumigatus 26.05 2.00e-23 103.00
IUUC-Ani-009154 Aspergillus nidulans 25.93 8.00e-26 111.00
IUUC-Ang-009803 Aspergillus niger 24.94 2.00e-20 94.00
IUUC-Aor-009984 Aspergillus oryzae 27.72 8.00e-22 98.20
IUUC-Ate-010567 Aspergillus terreus 29.06 1.00e-05 43.90
IUUC-Ame-010950 Astyanax mexicanus 59.56 7.00e-103 367.00
IUUC-Bgr-011992 Blumeria graminis 25.55 6.00e-23 102.00
IUUC-Bta-012658 Bos taurus 88.30 3.00e-169 587.00
IUUC-Bci-013586 Botrytis cinerea 26.50 8.00e-22 98.20
IUUC-Bdi-014625 Brachypodium distachyon 31.17 2.00e-36 146.00
IUUC-Bol-015713 Brassica oleracea 29.92 3.00e-25 108.00
IUUC-Bra-017037 Brassica rapa 31.25 3.00e-28 119.00
IUUC-Cel-018483 Caenorhabditis elegans 35.90 6.00e-53 201.00
IUUC-Cja-019601 Callithrix jacchus 90.25 3.00e-180 624.00
IUUC-Cfa-020854 Canis familiaris 87.19 2.00e-164 571.00
IUUC-Cpo-021920 Cavia porcellus 91.09 2.00e-180 624.00
IUUC-Cre-022816 Chlamydomonas reinhardtii 31.05 2.00e-17 84.00
IUUC-Csa-023545 Chlorocebus sabaeus 89.42 2.00e-169 588.00
IUUC-Cin-025523 Ciona intestinalis 38.23 3.00e-62 232.00
IUUC-Csv-026141 Ciona savignyi 33.70 4.00e-55 208.00
IUUC-Cgl-026641 Colletotrichum gloeosporioides 30.43 3.00e-21 95.90
IUUC-Cne-026949 Cryptococcus neoformans 25.48 8.00e-07 48.50
IUUC-Cme-027334 Cyanidioschyzon merolae 28.61 3.00e-29 122.00
IUUC-Dre-027602 Danio rerio 59.89 4.00e-110 391.00
IUUC-Dno-029980 Dasypus novemcinctus 86.91 3.00e-167 580.00
IUUC-Dor-030627 Dipodomys ordii 89.14 3.00e-170 590.00
IUUC-Dse-031219 Dothistroma septosporum 23.70 8.00e-26 111.00
IUUC-Dme-031953 Drosophila melanogaster 27.43 3.00e-19 89.00
IUUC-Ete-032811 Echinops telfairi 82.45 7.00e-166 576.00
IUUC-Eca-033635 Equus caballus 89.69 3.00e-180 624.00
IUUC-Eeu-034584 Erinaceus europaeus 86.07 4.00e-180 624.00
IUUC-Fca-035710 Felis catus 88.86 1.00e-171 595.00
IUUC-Fal-037416 Ficedula albicollis 71.79 1.00e-122 432.00
IUUC-Fox-037908 Fusarium oxysporum 26.33 2.00e-25 110.00
IUUC-Fso-038283 Fusarium solani 27.20 6.00e-29 121.00
IUUC-Gmo-039567 Gadus morhua 52.34 7.00e-22 97.80
IUUC-Ggr-040097 Gaeumannomyces graminis 30.90 5.00e-21 95.50
IUUC-Gga-040757 Gallus gallus 73.33 3.00e-147 514.00
IUUC-Gac-042008 Gasterosteus aculeatus 51.38 3.00e-70 258.00
IUUC-Gma-044278 Glycine max 32.15 6.00e-40 158.00
IUUC-Ggo-044888 Gorilla gorilla 89.69 3.00e-179 620.00
IUUC-Hsa-046481 Homo sapiens 89.42 9.00e-179 619.00
IUUC-Hvu-047274 Hordeum vulgare 42.06 1.00e-18 85.90
IUUC-Itr-048925 Ictidomys tridecemlineatus 89.97 6.00e-170 589.00
IUUC-Kpa-049394 Komagataella pastoris 23.90 5.00e-17 82.00
IUUC-Lch-050347 Latimeria chalumnae 68.52 6.00e-138 483.00
IUUC-Lpe-051711 Leersia perrieri 30.37 3.00e-35 142.00
IUUC-Loc-052943 Lepisosteus oculatus 64.64 8.00e-101 360.00
IUUC-Lma-053231 Leptosphaeria maculans 27.67 1.00e-19 92.40
IUUC-Laf-053506 Loxodonta africana 88.02 6.00e-168 583.00
IUUC-Mcc-055863 Macaca mulatta 89.69 8.00e-172 596.00
IUUC-Meu-056343 Macropus eugenii 81.77 7.00e-162 563.00
IUUC-Mor-057266 Magnaporthe oryzae 32.20 1.00e-19 91.30
IUUC-Mtr-058337 Medicago truncatula 29.03 2.00e-31 130.00
IUUC-Mla-058905 Melampsora laricipopulina 29.72 2.00e-37 149.00
IUUC-Mga-059695 Meleagris gallopavo 71.38 3.00e-126 444.00
IUUC-Mvi-060538 Microbotryum violaceum 26.68 8.00e-31 128.00
IUUC-Mmr-061680 Microcebus murinus 89.14 1.00e-177 615.00
IUUC-Mdo-063013 Monodelphis domestica 82.73 7.00e-165 573.00
IUUC-Mac-064765 Musa acuminata 31.59 2.00e-37 150.00
IUUC-Mpu-066866 Mustela putorius furo 88.58 1.00e-152 532.00
IUUC-Mlu-067535 Myotis lucifugus 88.30 1.00e-177 615.00
IUUC-Nfi-068561 Neosartorya fischeri 25.99 1.00e-21 98.20
IUUC-Ncr-068700 Neurospora crassa 32.55 4.00e-25 109.00
IUUC-Nle-069709 Nomascus leucogenys 90.25 2.00e-173 601.00
IUUC-Opr-070983 Ochotona princeps 86.35 1.00e-171 595.00
IUUC-Ont-071734 Oreochromis niloticus 53.76 4.00e-90 324.00
IUUC-Oan-072762 Ornithorhynchus anatinus 68.90 2.00e-51 195.00
IUUC-Ocu-074733 Oryctolagus cuniculus 88.02 2.00e-177 614.00
IUUC-Oba-075943 Oryza barthii 30.65 3.00e-34 139.00
IUUC-Obr-076017 Oryza brachyantha 29.77 2.00e-34 140.00
IUUC-Ogl-077702 Oryza glaberrima 30.65 3.00e-34 139.00
IUUC-Ogu-078692 Oryza glumaepatula 30.49 4.00e-34 138.00
IUUC-Oin-079133 Oryza indica 30.65 3.00e-34 139.00
IUUC-Oni-082667 Oryza nivara 30.65 3.00e-34 139.00
IUUC-Opu-083858 Oryza punctata 29.69 2.00e-34 140.00
IUUC-Oru-084886 Oryza rufipogon 30.65 3.00e-34 139.00
IUUC-Osa-085512 Oryza sativa 30.65 3.00e-34 139.00
IUUC-Ola-087150 Oryzias latipes 50.41 1.00e-91 329.00
IUUC-Olu-087595 Ostreococcus lucimarinus 25.61 9.00e-24 104.00
IUUC-Oga-088647 Otolemur garnettii 88.30 1.00e-173 602.00
IUUC-Oar-089308 Ovis aries 88.30 2.00e-167 581.00
IUUC-Ptr-090543 Pan troglodytes 89.69 6.00e-179 619.00
IUUC-Pan-091907 Papio anubis 89.42 1.00e-170 592.00
IUUC-Psi-093888 Pelodiscus sinensis 76.60 5.00e-152 530.00
IUUC-Pno-094821 Phaeosphaeria nodorum 29.44 2.00e-19 90.50
IUUC-Ppa-095287 Physcomitrella patens 32.65 1.00e-41 163.00
IUUC-Pfo-097238 Poecilia formosa 53.44 3.00e-96 345.00
IUUC-Pab-097938 Pongo abelii 89.69 1.00e-179 622.00
IUUC-Pop-098899 Populus trichocarpa 30.29 1.00e-36 147.00
IUUC-Pca-100488 Procavia capensis 84.82 1.00e-100 359.00
IUUC-Ppe-101914 Prunus persica 31.87 1.00e-39 157.00
IUUC-Pva-102469 Pteropus vampyrus 84.40 1.00e-155 542.00
IUUC-Pgr-103388 Puccinia graminis 25.88 6.00e-27 115.00
IUUC-Ptt-103988 Puccinia triticina 25.13 4.00e-25 108.00
IUUC-Pte-104186 Pyrenophora teres 26.40 6.00e-20 92.00
IUUC-Pyt-104605 Pyrenophora triticirepentis 25.00 2.00e-19 90.50
IUUC-Rno-105071 Rattus norvegicus 95.26 0.00e+00 697.00
IUUC-Sce-106238 Saccharomyces cerevisiae 23.71 4.00e-15 75.90
IUUC-Sha-107200 Sarcophilus harrisii 81.48 7.00e-144 503.00
IUUC-Sja-108008 Schizosaccharomyces japonicus 22.38 7.00e-17 81.30
IUUC-Spo-108077 Schizosaccharomyces pombe 21.29 2.00e-05 43.50
IUUC-Ssl-108559 Sclerotinia sclerotiorum 26.33 4.00e-20 92.40
IUUC-Smo-109083 Selaginella moellendorffii 31.99 6.00e-41 161.00
IUUC-Sit-110306 Setaria italica 30.37 3.00e-36 145.00
IUUC-Sly-111409 Solanum lycopersicum 31.94 7.00e-38 151.00
IUUC-Stu-112852 Solanum tuberosum 31.41 2.00e-36 146.00
IUUC-Sar-112967 Sorex araneus 79.58 4.00e-80 290.00
IUUC-Sbi-114722 Sorghum bicolor 29.77 5.00e-34 138.00
IUUC-Sre-115089 Sporisorium reilianum 28.17 3.00e-26 112.00
IUUC-Ssc-115367 Sus scrofa 88.58 0.00e+00 627.00
IUUC-Tgu-117176 Taeniopygia guttata 70.28 7.00e-138 483.00
IUUC-Tru-118162 Takifugu rubripes 52.34 6.00e-94 337.00
IUUC-Tsy-119231 Tarsius syrichta 89.14 2.00e-178 618.00
IUUC-Tni-119962 Tetraodon nigroviridis 54.87 3.00e-90 325.00
IUUC-Tca-121100 Theobroma cacao 30.39 1.00e-36 147.00
IUUC-Tre-122015 Trichoderma reesei 32.23 6.00e-28 118.00
IUUC-Tvi-122573 Trichoderma virens 27.63 3.00e-29 122.00
IUUC-Tae-123664 Triticum aestivum 29.35 1.00e-33 137.00
IUUC-Tur-126843 Triticum urartu 29.35 2.00e-33 137.00
IUUC-Tme-127060 Tuber melanosporum 27.30 2.00e-34 139.00
IUUC-Ttr-128998 Tursiops truncatus 85.79 4.00e-173 600.00
IUUC-Uma-129524 Ustilago maydis 30.56 6.00e-30 125.00
IUUC-Vvi-130933 Vitis vinifera 31.27 4.00e-35 142.00
IUUC-Xtr-132968 Xenopus tropicalis 64.07 1.00e-124 439.00
IUUC-Xma-133355 Xiphophorus maculatus 52.47 2.00e-98 352.00
IUUC-Yli-134388 Yarrowia lipolytica 27.27 1.00e-28 120.00
IUUC-Zma-135423 Zea mays 29.77 1.00e-34 140.00
Created Date 25-Jun-2017

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