iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092762

Ensembl Protein ID

ENSPANP00000011178.1

UniProt Accession

A0A096NE69; A0A096NE69_PAPAN

Genbank Protein ID

ENSPANP00000011178

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01061674

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000011197.1	ENSPANT00000015247.1	ENSPANP00000011178.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-19	69.5	33	96
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.90e-14	50.6	132	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+++ f+ah+ivLaa+S++F a+f++el+e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 33   CDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKG-KPYVDIQGLTASTMEILLDFVYTETV 96
           9***********************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 132  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 163
           89*****************************6 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MGGIMAPKDI MTNTHAKSIL NSMNSLRKSN TLCDVTLRVE QKDFPAHRIV LAACSDYFCA 60
MFTSELSEKG KPYVDIQGLT ASTMEILLDF VYTETVHVTV ENVQELLPAA CLLQLKGVKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTCCAGCT GCATTGCGTC ATCACGTCGC GCGGCCGCAG GGACCAGACC TGGACGGCTC 60
CAGAGCCTCC AGAGCCTCCG GGTGGGGGCG GCGGCGGCGG CTCTTCGGCT CTTCCTGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	98.22	0.00e+00	1107.00
IUUC-Apl-003339	Anas platyrhynchos	95.77	0.00e+00	1009.00
IUUC-Aca-004418	Anolis carolinensis	95.22	0.00e+00	1094.00
IUUC-Ame-011906	Astyanax mexicanus	74.69	0.00e+00	859.00
IUUC-Bta-012979	Bos taurus	96.31	0.00e+00	1106.00
IUUC-Cja-019582	Callithrix jacchus	98.07	0.00e+00	1127.00
IUUC-Cfa-020716	Canis familiaris	98.77	0.00e+00	1134.00
IUUC-Cpo-022013	Cavia porcellus	98.59	0.00e+00	1133.00
IUUC-Csa-023424	Chlorocebus sabaeus	98.86	0.00e+00	1052.00
IUUC-Cho-024586	Choloepus hoffmanni	80.49	0.00e+00	881.00
IUUC-Dre-028344	Danio rerio	88.67	8.00e-168	582.00
IUUC-Dno-028854	Dasypus novemcinctus	98.77	0.00e+00	1135.00
IUUC-Dor-030403	Dipodomys ordii	98.59	0.00e+00	1132.00
IUUC-Ete-032963	Echinops telfairi	96.63	0.00e+00	972.00
IUUC-Eca-033282	Equus caballus	98.59	0.00e+00	1134.00
IUUC-Eeu-034933	Erinaceus europaeus	96.48	1.00e-136	479.00
IUUC-Fca-035487	Felis catus	98.77	0.00e+00	1135.00
IUUC-Fal-037059	Ficedula albicollis	94.71	0.00e+00	1088.00
IUUC-Gmo-039564	Gadus morhua	88.69	0.00e+00	1066.00
IUUC-Gga-040629	Gallus gallus	95.38	0.00e+00	1094.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.24	0.00e+00	1067.00
IUUC-Ggo-044839	Gorilla gorilla	98.95	0.00e+00	1138.00
IUUC-Hsa-046742	Homo sapiens	98.95	0.00e+00	1138.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	98.59	0.00e+00	1133.00
IUUC-Lch-049540	Latimeria chalumnae	92.74	0.00e+00	1102.00
IUUC-Loc-051923	Lepisosteus oculatus	91.86	0.00e+00	1067.00
IUUC-Laf-054370	Loxodonta africana	98.24	0.00e+00	1131.00
IUUC-Mcc-054852	Macaca mulatta	98.95	0.00e+00	1138.00
IUUC-Mor-057181	Magnaporthe oryzae	25.11	6.00e-12	65.10
IUUC-Mga-059486	Meleagris gallopavo	94.14	0.00e+00	998.00
IUUC-Mmr-061777	Microcebus murinus	98.59	0.00e+00	1131.00
IUUC-Mdo-061990	Monodelphis domestica	96.83	0.00e+00	1114.00
IUUC-Mmu-064053	Mus musculus	98.24	0.00e+00	1132.00
IUUC-Mpu-066623	Mustela putorius furo	85.86	0.00e+00	813.00
IUUC-Mlu-067648	Myotis lucifugus	97.89	0.00e+00	1154.00
IUUC-Nle-069714	Nomascus leucogenys	98.77	0.00e+00	1137.00
IUUC-Opr-071143	Ochotona princeps	91.92	0.00e+00	1036.00
IUUC-Ont-071848	Oreochromis niloticus	89.91	0.00e+00	1074.00
IUUC-Oan-073041	Ornithorhynchus anatinus	97.51	2.00e-165	574.00
IUUC-Ocu-074379	Oryctolagus cuniculus	98.07	0.00e+00	1128.00
IUUC-Oin-079973	Oryza indica	32.63	8.00e-33	135.00
IUUC-Ola-087469	Oryzias latipes	89.91	0.00e+00	1074.00
IUUC-Oga-088004	Otolemur garnettii	99.16	6.00e-142	496.00
IUUC-Oar-090144	Ovis aries	97.36	0.00e+00	1118.00
IUUC-Ptr-091406	Pan troglodytes	98.95	0.00e+00	1138.00
IUUC-Psi-093391	Pelodiscus sinensis	94.87	0.00e+00	1095.00
IUUC-Pma-094134	Petromyzon marinus	73.19	0.00e+00	814.00
IUUC-Pfo-096404	Poecilia formosa	89.96	0.00e+00	1077.00
IUUC-Pab-098425	Pongo abelii	98.06	0.00e+00	1122.00
IUUC-Pca-101093	Procavia capensis	99.66	2.00e-173	602.00
IUUC-Pva-102239	Pteropus vampyrus	88.05	0.00e+00	1013.00
IUUC-Rno-104921	Rattus norvegicus	98.42	0.00e+00	1135.00
IUUC-Sha-106625	Sarcophilus harrisii	97.71	0.00e+00	1124.00
IUUC-Sar-113468	Sorex araneus	86.35	0.00e+00	699.00
IUUC-Ssc-116106	Sus scrofa	98.42	0.00e+00	1130.00
IUUC-Tgu-117402	Taeniopygia guttata	74.44	0.00e+00	740.00
IUUC-Tru-117546	Takifugu rubripes	89.38	0.00e+00	1068.00
IUUC-Tsy-118802	Tarsius syrichta	88.71	0.00e+00	981.00
IUUC-Tni-119999	Tetraodon nigroviridis	89.05	0.00e+00	1062.00
IUUC-Tca-121074	Theobroma cacao	31.56	1.00e-36	148.00
IUUC-Tbe-127987	Tupaia belangeri	98.28	0.00e+00	947.00
IUUC-Ttr-128613	Tursiops truncatus	91.37	0.00e+00	1027.00
IUUC-Xtr-132401	Xenopus tropicalis	92.23	7.00e-175	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence