iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133646

Ensembl Protein ID

ENSXMAP00000008082.1

UniProt Accession

M4A0T8; M4A0T8_XIPMA

Genbank Protein ID

ENSXMAP00000008082

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01026336

Gene Name

FBXW7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008053.1	ENSXMAT00000008092.1	ENSXMAP00000008082.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-61	200.2	470	503
UBD/Beta-Prp	5.50e-103	344.3	221	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtcl+f+ ++++++sdDgt+k+WDl+tg  
   Q: 470  HQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 503
           9*********449******************976 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           k+lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++ ++  i+++gs+Drt+kvw+ +tg+c+htl 
   Q: 221  KVLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAITGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLY 305
           689*************..*******************************************..************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+++v+++++++  +++vsGs+d t+rvwd+etgqcl+ +l gh ++v+cv++++  + +vsG++D +v++Wd +t+++l+tl+g ht
   Q: 306  GHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLH-VLMGHVAAVRCVQYDG--RRVVSGAYDFMVKVWDPETETCLHTLQG-HT 388
           *************..************************.****************..***************************9.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++vysl+fd    ++vsgsld+++++wd++tg+c++tl+gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq+++++ ++
   Q: 389  NRVYSLQFDG--IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSA 473
           *********9..9**************************************..************************************ PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
           v++l+f++n +++ s+d++v++w+lk+ e+
   Q: 474  VTCLQFNKNFVITSSDDGTVKLWDLKTGEF 503
           *************************98776 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MGFYGTLKMI FYKMKRKLDH GPEVRSFPSG KKPCKGPEYP SPTGIVPCPA TPTTFGHIRA 60
ANGQGQQRRR ITSIQPPTGL QEWLRTFQSW SGPEKLLALD ELIDSCEPTQ VKHMMQVIEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGTTCT ACGGCACTTT AAAGATGATT TTCTACAAAG TGAGTATGGT CGGCTCCGGC 60
CGCTGCAGAG GAAGAGTCGC GGTGTGACGG ACCCCCACCT CTTCCTCTCC TCCCCAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	95.02	0.00e+00	1049.00
IUUC-Apl-003489	Anas platyrhynchos	94.02	0.00e+00	1051.00
IUUC-Aca-005318	Anolis carolinensis	95.49	0.00e+00	1075.00
IUUC-Ago-007794	Ashbya gossypii	30.80	2.00e-60	226.00
IUUC-Acl-008123	Aspergillus clavatus	32.07	6.00e-75	275.00
IUUC-Afl-008730	Aspergillus flavus	31.82	3.00e-73	270.00
IUUC-Afu-009014	Aspergillus fumigatus	32.67	2.00e-74	273.00
IUUC-Ani-009332	Aspergillus nidulans	32.74	3.00e-79	289.00
IUUC-Ang-009529	Aspergillus niger	33.40	6.00e-75	275.00
IUUC-Aor-010215	Aspergillus oryzae	30.84	5.00e-73	268.00
IUUC-Ate-010535	Aspergillus terreus	32.42	1.00e-75	277.00
IUUC-Ame-010898	Astyanax mexicanus	95.76	0.00e+00	1049.00
IUUC-Bgr-012075	Blumeria graminis	33.40	2.00e-79	290.00
IUUC-Bta-012391	Bos taurus	95.49	0.00e+00	1074.00
IUUC-Bci-013725	Botrytis cinerea	33.40	2.00e-77	283.00
IUUC-Cel-018495	Caenorhabditis elegans	48.44	2.00e-129	455.00
IUUC-Cja-018902	Callithrix jacchus	95.39	0.00e+00	1051.00
IUUC-Cfa-020237	Canis familiaris	95.39	0.00e+00	1049.00
IUUC-Cpo-022234	Cavia porcellus	95.49	0.00e+00	1076.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	38.79	2.00e-49	189.00
IUUC-Csa-023532	Chlorocebus sabaeus	95.39	0.00e+00	1052.00
IUUC-Cho-025026	Choloepus hoffmanni	78.00	0.00e+00	691.00
IUUC-Cin-025516	Ciona intestinalis	70.77	5.00e-139	487.00
IUUC-Csv-026312	Ciona savignyi	74.69	0.00e+00	743.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	35.15	4.00e-86	312.00
IUUC-Cne-027018	Cryptococcus neoformans	32.57	4.00e-72	266.00
IUUC-Cme-027168	Cyanidioschyzon merolae	31.10	2.00e-30	127.00
IUUC-Dre-028303	Danio rerio	93.91	0.00e+00	1037.00
IUUC-Dno-029576	Dasypus novemcinctus	92.70	0.00e+00	1033.00
IUUC-Dor-030196	Dipodomys ordii	93.91	0.00e+00	1026.00
IUUC-Dme-031702	Drosophila melanogaster	73.23	0.00e+00	792.00
IUUC-Ete-032791	Echinops telfairi	87.80	0.00e+00	962.00
IUUC-Eca-033424	Equus caballus	95.49	0.00e+00	1075.00
IUUC-Eeu-034996	Erinaceus europaeus	92.44	0.00e+00	1017.00
IUUC-Fca-036422	Felis catus	94.71	0.00e+00	1053.00
IUUC-Fal-037267	Ficedula albicollis	93.98	0.00e+00	1045.00
IUUC-Fox-037800	Fusarium oxysporum	34.54	1.00e-84	307.00
IUUC-Fso-038258	Fusarium solani	34.55	1.00e-84	307.00
IUUC-Gmo-039119	Gadus morhua	87.55	0.00e+00	951.00
IUUC-Ggr-039781	Gaeumannomyces graminis	35.19	2.00e-85	310.00
IUUC-Gga-040667	Gallus gallus	94.70	0.00e+00	1053.00
IUUC-Gac-042423	Gasterosteus aculeatus	75.86	0.00e+00	834.00
IUUC-Ggo-044422	Gorilla gorilla	95.39	0.00e+00	1053.00
IUUC-Hsa-045898	Homo sapiens	95.39	0.00e+00	1053.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	97.86	0.00e+00	942.00
IUUC-Kpa-049097	Komagataella pastoris	31.35	9.00e-77	281.00
IUUC-Lch-050414	Latimeria chalumnae	95.76	0.00e+00	1056.00
IUUC-Loc-052348	Lepisosteus oculatus	97.65	0.00e+00	1099.00
IUUC-Lma-053185	Leptosphaeria maculans	32.87	3.00e-73	270.00
IUUC-Laf-054054	Loxodonta africana	95.20	0.00e+00	1050.00
IUUC-Mcc-055056	Macaca mulatta	95.39	0.00e+00	1052.00
IUUC-Meu-056778	Macropus eugenii	89.94	3.00e-166	578.00
IUUC-Mor-057076	Magnaporthe oryzae	34.65	4.00e-85	308.00
IUUC-Mpo-057423	Magnaporthe poae	39.94	8.00e-72	265.00
IUUC-Mla-059081	Melampsora laricipopulina	34.41	5.00e-80	292.00
IUUC-Mga-059255	Meleagris gallopavo	94.53	0.00e+00	1051.00
IUUC-Mvi-060490	Microbotryum violaceum	38.16	1.00e-66	249.00
IUUC-Mmr-061292	Microcebus murinus	95.39	0.00e+00	1051.00
IUUC-Mdo-062304	Monodelphis domestica	94.71	0.00e+00	1057.00
IUUC-Mmu-063610	Mus musculus	93.84	0.00e+00	1051.00
IUUC-Mpu-065931	Mustela putorius furo	95.39	0.00e+00	1050.00
IUUC-Mlu-066976	Myotis lucifugus	94.02	0.00e+00	1053.00
IUUC-Nfi-068428	Neosartorya fischeri	32.06	1.00e-74	274.00
IUUC-Ncr-068688	Neurospora crassa	36.10	2.00e-87	317.00
IUUC-Nle-070174	Nomascus leucogenys	95.39	0.00e+00	1053.00
IUUC-Opr-070851	Ochotona princeps	80.31	4.00e-174	604.00
IUUC-Ont-071997	Oreochromis niloticus	97.83	0.00e+00	1124.00
IUUC-Oan-072936	Ornithorhynchus anatinus	94.89	0.00e+00	1056.00
IUUC-Ocu-074742	Oryctolagus cuniculus	94.20	0.00e+00	1053.00
IUUC-Obr-076806	Oryza brachyantha	31.52	2.00e-29	125.00
IUUC-Oin-079809	Oryza indica	31.52	1.00e-29	125.00
IUUC-Ola-087098	Oryzias latipes	96.34	0.00e+00	1088.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.85	1.00e-38	153.00
IUUC-Oga-088884	Otolemur garnettii	97.37	0.00e+00	757.00
IUUC-Oar-090220	Ovis aries	94.69	0.00e+00	1047.00
IUUC-Ptr-090492	Pan troglodytes	95.39	0.00e+00	1053.00
IUUC-Pan-091770	Papio anubis	95.39	0.00e+00	1052.00
IUUC-Psi-093207	Pelodiscus sinensis	95.49	0.00e+00	1077.00
IUUC-Pma-094749	Petromyzon marinus	83.33	0.00e+00	959.00
IUUC-Pno-095026	Phaeosphaeria nodorum	38.67	1.00e-71	265.00
IUUC-Pfo-096493	Poecilia formosa	99.82	0.00e+00	1096.00
IUUC-Pab-098141	Pongo abelii	95.49	0.00e+00	1075.00
IUUC-Pca-100571	Procavia capensis	93.47	0.00e+00	731.00
IUUC-Pva-102988	Pteropus vampyrus	94.88	0.00e+00	1052.00
IUUC-Pgr-103612	Puccinia graminis	35.48	5.00e-62	233.00
IUUC-Pte-104275	Pyrenophora teres	32.07	5.00e-74	272.00
IUUC-Pyt-104438	Pyrenophora triticirepentis	31.88	1.00e-73	271.00
IUUC-Rno-105706	Rattus norvegicus	94.16	0.00e+00	1050.00
IUUC-Sce-106314	Saccharomyces cerevisiae	29.78	8.00e-62	232.00
IUUC-Sha-107653	Sarcophilus harrisii	94.71	0.00e+00	1052.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	33.02	7.00e-79	288.00
IUUC-Sar-113600	Sorex araneus	88.75	0.00e+00	957.00
IUUC-Sre-114901	Sporisorium reilianum	48.13	5.00e-67	249.00
IUUC-Ssc-115787	Sus scrofa	92.88	0.00e+00	1023.00
IUUC-Tgu-117510	Taeniopygia guttata	94.52	0.00e+00	1050.00
IUUC-Tru-117819	Takifugu rubripes	98.34	0.00e+00	1107.00
IUUC-Tsy-118828	Tarsius syrichta	95.39	0.00e+00	1051.00
IUUC-Tni-120468	Tetraodon nigroviridis	97.83	0.00e+00	1121.00
IUUC-Tre-122193	Trichoderma reesei	36.54	7.00e-86	311.00
IUUC-Tvi-122615	Trichoderma virens	34.76	2.00e-83	303.00
IUUC-Tme-127021	Tuber melanosporum	35.44	2.00e-85	310.00
IUUC-Tbe-127925	Tupaia belangeri	95.38	0.00e+00	1048.00
IUUC-Ttr-128899	Tursiops truncatus	95.02	0.00e+00	1048.00
IUUC-Uma-129449	Ustilago maydis	46.89	4.00e-66	247.00
IUUC-Vda-129802	Verticillium dahliae	36.94	8.00e-89	321.00
IUUC-Vpa-130082	Vicugna pacos	94.70	0.00e+00	873.00
IUUC-Xtr-132213	Xenopus tropicalis	95.20	0.00e+00	1054.00
IUUC-Yli-134429	Yarrowia lipolytica	34.33	6.00e-87	315.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence