iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074824

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02009869

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002549.2	ENSOCUT00000002551.2	ENSOCUP00000002202.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-35	120.1	231	261
UBD/Beta-Prp	7.70e-59	199.3	55	274

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 231  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 261
           99*********999****************7 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkgh 93
           ++h +++ + k++p++ ++a+g ++++ ++ d +   l  +++   +++++v + +d+k ++ ++e   ++  v+  ++g+ v  ++gh
   Q: 55   TEHAHQVVVAKYAPSGFYIASGAYSSRFQLSDQKXHLLKYEYQPFAGKIKDVAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITGH 143
           4566667778*************************9998888999999***********99999999887777777789********** PP
   S: 94   edsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tggh 179
           ++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   ++h
   Q: 144  NKVINSVDIRQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALgeGKAH 231
           ***********999*****************9999998.99******************************************99556* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           ++ +y +s+++++++l+s+s d+t k+wd+  +++v t+   +
   Q: 232  DGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGS 274
           **********************************999997554 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MPYEIEKVFA SLPQVERGVS KILGGDPKGD NFLYTNGKCV ILRNIDNPAI ADIYTEHAHQ 60
VVVAKYAPSG FYIASGAYSS RFQLSDQKXH LLKYEYQPFA GKIKDVAWTE DSKRIAVVGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGTACG AAATCGTAAG TGGAGGAGGG CCCCGGGATC CTCAGGGTAG GGGGTCTTGA 60
AGAACATGAG GGTTTTTTGG CATCCTGGGA TGTTGGCTGG AGCCTGACCT GGGGTTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.07	2.00e-82	299.00
IUUC-Aml-002368	Ailuropoda melanoleuca	94.68	0.00e+00	1151.00
IUUC-Atr-003160	Amborella trichopoda	35.67	1.00e-107	384.00
IUUC-Apl-004012	Anas platyrhynchos	85.81	0.00e+00	1052.00
IUUC-Aca-004707	Anolis carolinensis	80.86	0.00e+00	1018.00
IUUC-Aly-006465	Arabidopsis lyrata	36.48	1.00e-105	377.00
IUUC-Ath-006740	Arabidopsis thaliana	35.67	3.00e-104	372.00
IUUC-Ago-007920	Ashbya gossypii	28.12	4.00e-72	265.00
IUUC-Acl-008262	Aspergillus clavatus	36.81	1.00e-106	380.00
IUUC-Afl-008471	Aspergillus flavus	30.39	5.00e-64	238.00
IUUC-Afu-008989	Aspergillus fumigatus	38.67	6.00e-96	344.00
IUUC-Ani-009167	Aspergillus nidulans	37.91	1.00e-114	407.00
IUUC-Ang-009595	Aspergillus niger	39.11	3.00e-103	369.00
IUUC-Aor-009908	Aspergillus oryzae	36.69	1.00e-100	360.00
IUUC-Ate-010580	Aspergillus terreus	37.66	3.00e-108	387.00
IUUC-Ame-011269	Astyanax mexicanus	58.00	5.00e-126	444.00
IUUC-Bgr-011996	Blumeria graminis	34.69	2.00e-105	375.00
IUUC-Bta-013278	Bos taurus	92.90	0.00e+00	1169.00
IUUC-Bci-013925	Botrytis cinerea	35.56	4.00e-106	378.00
IUUC-Bdi-014659	Brachypodium distachyon	35.14	2.00e-101	362.00
IUUC-Bol-016043	Brassica oleracea	34.53	1.00e-101	363.00
IUUC-Bra-017139	Brassica rapa	35.07	3.00e-103	369.00
IUUC-Cel-018417	Caenorhabditis elegans	39.97	8.00e-119	420.00
IUUC-Cja-019952	Callithrix jacchus	93.56	0.00e+00	1132.00
IUUC-Cfa-020225	Canis familiaris	94.06	0.00e+00	1157.00
IUUC-Cpo-021900	Cavia porcellus	92.01	0.00e+00	1137.00
IUUC-Csa-023028	Chlorocebus sabaeus	94.22	0.00e+00	1136.00
IUUC-Cho-025030	Choloepus hoffmanni	65.83	0.00e+00	717.00
IUUC-Cin-025152	Ciona intestinalis	52.92	1.00e-74	272.00
IUUC-Csv-025986	Ciona savignyi	37.42	4.00e-92	331.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.01	3.00e-109	389.00
IUUC-Cne-026814	Cryptococcus neoformans	32.63	8.00e-90	324.00
IUUC-Dre-027498	Danio rerio	74.36	7.00e-87	312.00
IUUC-Dno-029383	Dasypus novemcinctus	91.91	0.00e+00	1110.00
IUUC-Dor-030633	Dipodomys ordii	92.69	0.00e+00	1065.00
IUUC-Dse-031526	Dothistroma septosporum	37.54	8.00e-113	400.00
IUUC-Dme-031597	Drosophila melanogaster	47.11	2.00e-162	565.00
IUUC-Ete-032780	Echinops telfairi	81.61	0.00e+00	1008.00
IUUC-Eca-034306	Equus caballus	93.01	0.00e+00	1120.00
IUUC-Eeu-034531	Erinaceus europaeus	72.47	2.00e-130	459.00
IUUC-Fca-036301	Felis catus	94.34	0.00e+00	1175.00
IUUC-Fal-037361	Ficedula albicollis	85.79	0.00e+00	1097.00
IUUC-Fox-037924	Fusarium oxysporum	34.91	6.00e-101	361.00
IUUC-Fso-038199	Fusarium solani	34.81	2.00e-97	349.00
IUUC-Gmo-039238	Gadus morhua	70.68	0.00e+00	869.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.88	3.00e-94	339.00
IUUC-Gga-040235	Gallus gallus	86.80	0.00e+00	1079.00
IUUC-Gac-042363	Gasterosteus aculeatus	70.02	0.00e+00	898.00
IUUC-Gma-044189	Glycine max	35.90	2.00e-106	379.00
IUUC-Ggo-044632	Gorilla gorilla	92.09	0.00e+00	1105.00
IUUC-Hsa-045792	Homo sapiens	93.89	0.00e+00	1157.00
IUUC-Hvu-047517	Hordeum vulgare	34.59	7.00e-105	374.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	95.34	0.00e+00	1160.00
IUUC-Kpa-049183	Komagataella pastoris	32.89	7.00e-82	297.00
IUUC-Lch-050428	Latimeria chalumnae	73.81	0.00e+00	963.00
IUUC-Lpe-051306	Leersia perrieri	35.35	2.00e-106	379.00
IUUC-Loc-052096	Lepisosteus oculatus	70.29	0.00e+00	870.00
IUUC-Lma-053313	Leptosphaeria maculans	39.05	2.00e-115	411.00
IUUC-Laf-054060	Loxodonta africana	90.26	0.00e+00	1109.00
IUUC-Mcc-055619	Macaca mulatta	92.14	0.00e+00	1107.00
IUUC-Meu-056689	Macropus eugenii	78.14	0.00e+00	628.00
IUUC-Mor-056940	Magnaporthe oryzae	35.55	5.00e-96	345.00
IUUC-Mpo-057557	Magnaporthe poae	30.45	2.00e-66	246.00
IUUC-Mtr-058478	Medicago truncatula	34.59	2.00e-103	369.00
IUUC-Mla-059103	Melampsora laricipopulina	32.92	5.00e-72	265.00
IUUC-Mga-060150	Meleagris gallopavo	86.75	0.00e+00	1071.00
IUUC-Mvi-060448	Microbotryum violaceum	30.51	3.00e-69	256.00
IUUC-Mmr-061226	Microcebus murinus	92.08	0.00e+00	1128.00
IUUC-Mdo-062674	Monodelphis domestica	89.60	0.00e+00	1114.00
IUUC-Mmu-064170	Mus musculus	94.06	0.00e+00	1164.00
IUUC-Mac-065124	Musa acuminata	36.89	2.00e-109	389.00
IUUC-Mpu-066001	Mustela putorius furo	90.78	0.00e+00	1140.00
IUUC-Mlu-067253	Myotis lucifugus	92.51	0.00e+00	1142.00
IUUC-Nfi-068550	Neosartorya fischeri	38.83	5.00e-111	394.00
IUUC-Ncr-068948	Neurospora crassa	36.55	4.00e-113	402.00
IUUC-Nle-070115	Nomascus leucogenys	91.39	0.00e+00	1043.00
IUUC-Opr-070254	Ochotona princeps	94.00	0.00e+00	1103.00
IUUC-Ont-071666	Oreochromis niloticus	73.76	0.00e+00	931.00
IUUC-Oan-073594	Ornithorhynchus anatinus	92.19	1.00e-167	582.00
IUUC-Oba-075010	Oryza barthii	35.74	2.00e-107	383.00
IUUC-Obr-076364	Oryza brachyantha	36.27	3.00e-108	385.00
IUUC-Ogl-077019	Oryza glaberrima	35.74	2.00e-107	383.00
IUUC-Ogu-078496	Oryza glumaepatula	35.74	2.00e-107	383.00
IUUC-Oin-080116	Oryza indica	35.90	5.00e-108	384.00
IUUC-Olo-080290	Oryza longistaminata	35.74	3.00e-107	382.00
IUUC-Ome-081969	Oryza meridionalis	35.74	2.00e-107	382.00
IUUC-Oni-082075	Oryza nivara	35.74	2.00e-107	383.00
IUUC-Opu-083959	Oryza punctata	35.78	2.00e-107	382.00
IUUC-Oru-084711	Oryza rufipogon	35.74	2.00e-107	383.00
IUUC-Osa-085958	Oryza sativa	35.90	5.00e-108	384.00
IUUC-Ola-086968	Oryzias latipes	75.08	0.00e+00	942.00
IUUC-Oga-089108	Otolemur garnettii	93.13	0.00e+00	1178.00
IUUC-Oar-089986	Ovis aries	87.38	0.00e+00	1080.00
IUUC-Ptr-091281	Pan troglodytes	94.33	0.00e+00	1150.00
IUUC-Pan-092585	Papio anubis	94.39	0.00e+00	1138.00
IUUC-Psi-093811	Pelodiscus sinensis	84.72	0.00e+00	1084.00
IUUC-Pma-094542	Petromyzon marinus	67.71	0.00e+00	853.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.88	8.00e-108	384.00
IUUC-Ppa-095876	Physcomitrella patens	35.74	1.00e-107	383.00
IUUC-Pfo-096973	Poecilia formosa	73.43	0.00e+00	959.00
IUUC-Pab-098391	Pongo abelii	94.06	0.00e+00	1140.00
IUUC-Pop-098850	Populus trichocarpa	35.19	4.00e-106	378.00
IUUC-Pca-100257	Procavia capensis	60.26	3.00e-91	329.00
IUUC-Ppe-101578	Prunus persica	37.15	6.00e-110	391.00
IUUC-Pva-102872	Pteropus vampyrus	87.97	0.00e+00	1098.00
IUUC-Pgr-103593	Puccinia graminis	32.72	3.00e-75	276.00
IUUC-Pte-104365	Pyrenophora teres	39.06	1.00e-109	390.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.74	3.00e-112	399.00
IUUC-Rno-105737	Rattus norvegicus	94.22	0.00e+00	1187.00
IUUC-Sce-106383	Saccharomyces cerevisiae	27.80	3.00e-63	236.00
IUUC-Sha-107084	Sarcophilus harrisii	87.17	0.00e+00	972.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	34.48	9.00e-105	374.00
IUUC-Spo-108309	Schizosaccharomyces pombe	32.68	2.00e-91	330.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.56	1.00e-106	380.00
IUUC-Smo-109255	Selaginella moellendorffii	33.44	1.00e-94	340.00
IUUC-Sit-109962	Setaria italica	36.99	7.00e-110	390.00
IUUC-Sly-110897	Solanum lycopersicum	36.33	4.00e-109	388.00
IUUC-Stu-111971	Solanum tuberosum	36.33	2.00e-108	386.00
IUUC-Sar-113415	Sorex araneus	67.16	3.00e-99	355.00
IUUC-Sbi-114857	Sorghum bicolor	36.50	2.00e-107	383.00
IUUC-Sre-114900	Sporisorium reilianum	32.52	5.00e-86	311.00
IUUC-Tgu-117256	Taeniopygia guttata	86.21	0.00e+00	1097.00
IUUC-Tru-117871	Takifugu rubripes	68.93	0.00e+00	864.00
IUUC-Tsy-119172	Tarsius syrichta	93.62	2.00e-131	462.00
IUUC-Tni-120339	Tetraodon nigroviridis	68.32	0.00e+00	895.00
IUUC-Tca-121609	Theobroma cacao	35.49	1.00e-106	380.00
IUUC-Tre-122076	Trichoderma reesei	35.56	4.00e-94	338.00
IUUC-Tvi-122528	Trichoderma virens	34.53	5.00e-97	348.00
IUUC-Tae-124549	Triticum aestivum	34.92	8.00e-106	377.00
IUUC-Tur-126845	Triticum urartu	35.04	1.00e-81	296.00
IUUC-Tme-127217	Tuber melanosporum	34.76	2.00e-100	359.00
IUUC-Tbe-127526	Tupaia belangeri	91.75	0.00e+00	1136.00
IUUC-Ttr-128898	Tursiops truncatus	85.34	0.00e+00	1061.00
IUUC-Uma-129631	Ustilago maydis	31.16	6.00e-88	318.00
IUUC-Vda-129732	Verticillium dahliae	35.24	3.00e-91	328.00
IUUC-Vvi-131217	Vitis vinifera	36.64	6.00e-107	381.00
IUUC-Xtr-132860	Xenopus tropicalis	72.10	0.00e+00	918.00
IUUC-Xma-133830	Xiphophorus maculatus	73.43	0.00e+00	959.00
IUUC-Yli-134335	Yarrowia lipolytica	32.89	9.00e-75	274.00
IUUC-Zma-135907	Zea mays	36.66	2.00e-108	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence