iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121630

Ensembl Protein ID

EOY33217

UniProt Accession

A0A061GVP2; A0A061GVP2_THECC

Genbank Protein ID

EOY33217.1

Protein Name

Ubiquitin-specific protease 12 isoform 1

Genbank Nucleotide ID

CM001887

Gene Name

TCM_041172

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_041172	EOY33218	EOY33218
TCM_041172	EOY33217	EOY33217

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.80e-71	239.8	198	521

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflld 101
           +GlkN+g+tCYmNS+LQ+L++ip +r+++ +     ++ ++++ p+g++  +lq+lf +l ++++++v+++el+k++++    +++++q+D+qE+ ++l +
   Q: 198  VGLKNQGATCYMNSLLQTLYHIPYFRKAVYH-----MPTTENDMPSGSIPLALQSLFYKL-QYSDSSVATKELTKSFGWDT--YDSFMQHDVQELNRVLCE 290
           6******************************.....555556789***************.88999************877..67**************** PP
   S: 102  qleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
           +le+++                          k +  + +i++lF+g+  + i c + d +s+r+e+f+dl+l+v+g +     ++  +++++++ e+leg
   Q: 291  KLEDKM--------------------------KGTVVEGTIQQLFEGHHMNYIECINVDYKSTRKESFYDLQLDVKGCR-----DVYASFDKYVEVERLEG 360
           ******..........................7899*******************************************.....9**************** PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls....pfctspeekqkekkkYeLiavvvHsGslssGHYvayv 299
           +nky+ e+  ++q+a+k + +  +P+vL l+LkRf+++  ++   kin+++efpl+Ldl+    ++++  e + ++++ Y L++v+vHsG++++GHY+a++
   Q: 361  DNKYQAEQY-GLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLQLDLDrdegKYLSP-EADRSVRNLYTLHSVLVHSGGVHGGHYYAFI 459
           *******97.69***********************************************9877666666.666678************************* PP
   S: 300  kn.ekgkWllfdDskVtevkeeevleetg.......................staYvlfYkr 337
           +   +++W++fdD++Vt+ ++++ lee+                        s+aY+l+Y r
   Q: 460  RPtLSDQWYKFDDERVTKEDMKRALEEQYggeeelpqtnpgfnntpfkftkySNAYMLVYIR 521
           *945677*****************997779******************************87 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MTVMTPAPVD QQEDEEMLVP HSDLTDNHQP MEVAAQPETA STVENQPVED PPSSRFTWKI 60
ENFSRLNTKK HYSEVFPVGG FKWRILIFPK GNNVDHLSMY LDVADSASLP YGWSRYAQFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGAAAGAAT AAAATGGAGA TAAACGAAAA CAGAAAATTT GATATTTAAG GACAAAAATG 60
TTACATACTT TTTAAAATAA ATAAATTTAT ATTAGAATCT CATTTTGATT AATTGGAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	79.17	0.00e+00	1758.00
IUUC-Atr-003067	Amborella trichopoda	90.48	0.00e+00	1579.00
IUUC-Ago-007849	Ashbya gossypii	33.76	1.00e-141	497.00
IUUC-Acl-008327	Aspergillus clavatus	39.13	1.00e-179	623.00
IUUC-Afl-008491	Aspergillus flavus	39.26	0.00e+00	632.00
IUUC-Afu-008804	Aspergillus fumigatus	39.37	1.00e-172	600.00
IUUC-Ang-009776	Aspergillus niger	37.29	3.00e-176	612.00
IUUC-Aor-009998	Aspergillus oryzae	38.60	3.00e-176	611.00
IUUC-Ate-010428	Aspergillus terreus	39.16	0.00e+00	632.00
IUUC-Bgr-012132	Blumeria graminis	34.72	5.00e-165	574.00
IUUC-Bdi-015069	Brachypodium distachyon	85.31	0.00e+00	1878.00
IUUC-Cel-018219	Caenorhabditis elegans	28.79	5.00e-102	365.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	55.62	1.00e-144	505.00
IUUC-Csv-025963	Ciona savignyi	34.21	3.00e-151	528.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	37.10	3.00e-177	615.00
IUUC-Cme-027103	Cyanidioschyzon merolae	39.02	5.00e-126	445.00
IUUC-Dor-030611	Dipodomys ordii	50.45	5.00e-83	302.00
IUUC-Dse-031433	Dothistroma septosporum	35.93	1.00e-164	573.00
IUUC-Dme-031583	Drosophila melanogaster	34.89	9.00e-157	546.00
IUUC-Fox-037695	Fusarium oxysporum	36.85	0.00e+00	639.00
IUUC-Gma-043081	Glycine max	91.15	0.00e+00	2041.00
IUUC-Hvu-047749	Hordeum vulgare	84.23	0.00e+00	1575.00
IUUC-Lpe-051543	Leersia perrieri	84.31	0.00e+00	1830.00
IUUC-Lma-053169	Leptosphaeria maculans	36.58	2.00e-173	602.00
IUUC-Mor-057149	Magnaporthe oryzae	34.80	2.00e-167	582.00
IUUC-Mtr-058583	Medicago truncatula	89.45	0.00e+00	2014.00
IUUC-Mla-058899	Melampsora laricipopulina	39.50	0.00e+00	680.00
IUUC-Mvi-060207	Microbotryum violaceum	38.89	0.00e+00	670.00
IUUC-Nfi-068342	Neosartorya fischeri	39.78	4.00e-174	604.00
IUUC-Oba-075811	Oryza barthii	82.69	0.00e+00	1788.00
IUUC-Obr-076226	Oryza brachyantha	86.19	0.00e+00	1907.00
IUUC-Ogl-077912	Oryza glaberrima	85.98	0.00e+00	1879.00
IUUC-Ogu-078038	Oryza glumaepatula	80.16	0.00e+00	1814.00
IUUC-Oin-079513	Oryza indica	84.85	0.00e+00	1794.00
IUUC-Olo-081067	Oryza longistaminata	83.33	0.00e+00	1751.00
IUUC-Ome-081879	Oryza meridionalis	85.52	0.00e+00	1861.00
IUUC-Oni-082461	Oryza nivara	82.39	0.00e+00	1830.00
IUUC-Opu-083199	Oryza punctata	85.84	0.00e+00	1842.00
IUUC-Oru-085109	Oryza rufipogon	83.64	0.00e+00	1798.00
IUUC-Osa-085418	Oryza sativa	71.88	0.00e+00	1340.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.81	4.00e-157	548.00
IUUC-Pva-102472	Pteropus vampyrus	35.58	2.00e-160	559.00
IUUC-Pgr-103463	Puccinia graminis	39.16	0.00e+00	668.00
IUUC-Ptt-103716	Puccinia triticina	38.85	2.00e-179	622.00
IUUC-Pte-104360	Pyrenophora teres	37.67	6.00e-171	594.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	37.58	4.00e-170	591.00
IUUC-Sce-106230	Saccharomyces cerevisiae	33.50	7.00e-126	444.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	35.15	3.00e-149	521.00
IUUC-Smo-109308	Selaginella moellendorffii	78.65	0.00e+00	1774.00
IUUC-Sit-110268	Setaria italica	85.99	0.00e+00	1870.00
IUUC-Sly-111476	Solanum lycopersicum	86.01	0.00e+00	1909.00
IUUC-Stu-112333	Solanum tuberosum	86.46	0.00e+00	1926.00
IUUC-Sbi-114424	Sorghum bicolor	85.22	0.00e+00	1878.00
IUUC-Sre-115156	Sporisorium reilianum	38.33	0.00e+00	668.00
IUUC-Tvi-122600	Trichoderma virens	37.53	3.00e-179	622.00
IUUC-Tae-125233	Triticum aestivum	85.37	0.00e+00	1894.00
IUUC-Tur-126501	Triticum urartu	75.65	0.00e+00	1645.00
IUUC-Tbe-127696	Tupaia belangeri	43.27	2.00e-68	253.00
IUUC-Vvi-131048	Vitis vinifera	90.24	0.00e+00	2000.00
IUUC-Zma-135855	Zea mays	81.57	0.00e+00	1791.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence