iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000013330.1	ENSONIT00000016777.1	ENSONIP00000016762.1
ENSONIG00000013330.1	ENSONIT00000016778.1	ENSONIP00000016763.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-46	158.0	160	489

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaee.fsg 86
           +Gl+N+ +  Y N vLQ+ sn+p+lr+++le+++ +  ++ p +    l++ + +l+++lw   + k +vsp+e+l+a+  ++++ f+ 
   Q: 160  VGLNNIKANDYANVVLQAFSNVPPLRNYFLEEENYRGIRRPPGDIMFLLVQRFGELMRKLWnpRNFKAHVSPHEMLQAVVLCSKKnFQI 248
           6******************************99999999999*******************999999**************99999*** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk................sqikclec 159
           ++q Da +f++++l++l+ +l                           +kk++s+i++ Fqg ++                + +   + 
   Q: 249  TKQGDAVDFMTWFLNALHGAL-------------------------GGTKKKPSIITKAFQGYMRifskklphpdlppeekEALLTTDE 312
           *********************.........................5678899999999999999999999999999997777777778 PP
   S: 160  dnvssreepfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsf 239
            +++ +e++fl l+l++p     k e          l ++L++f    e e    y++ k     +  k+++l+klP++Li+ +kRf  
   Q: 313  YQEQMSESSFLFLTLDLPTAPLYKDEkeqliipqvPLFNILAKFNGSTEKE----YKTYK----ENFLKRFQLTKLPPYLIFCIKRF-- 391
           888899************777666555566777778888888888887777....44444....34899******************.. PP
   S: 240  seeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleet 326
           ++++ + ek+ + v+fp++ +dl++++t++ ++ +++++Y+Lia vvH G++ +G Y  +v +  +gkW+++ D +Vt +  + +    
   Q: 392  TKNNFFVEKNPTIVNFPITnVDLREYLTEEAQATEKNTTYDLIANVVHDGKPTEGAYRIHVLHhGTGKWYEMQDLQVTDILPQMITL-- 478
           88889********************************************************9935666******************9.. PP
   S: 327  gstaYvlfYkrr 338
            s+aY+ ++kr+
   Q: 479  -SEAYIQIWKRQ 489
           .********986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MVSLKREREV DLDDDDDNED GVAAKVGRGH AVEDRRSRHC PYLDTINRSV LDFDFEKLCS 60
ISLSHINVYA CLICGKYFQG RGLKSHAYTH SVQFTHHVFL NLHTLKFYCL PDNYEIIDSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCAAATAAC GTAAAGGTTT AGCTTCTAAA TTGTTTTGAC GCCGTCTATC TGCTGCTATG 60
GTTTCTTTGA AGCGAGAAAG AGAGGTGGAT TTAGATGATG ATGATGACAA TGAAGACGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0048855--P:adenohypophysis morphogenesis
GO:0016579--P:protein deubiquitination
GO:0043484--P:regulation of RNA splicing
GO:0000245--P:spliceosomal complex assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000483	Aegilops tauschii	53.36	2.00e-130	459.00
IUUC-Aml-001846	Ailuropoda melanoleuca	85.80	0.00e+00	869.00
IUUC-Atr-002758	Amborella trichopoda	51.67	6.00e-131	461.00
IUUC-Apl-003336	Anas platyrhynchos	81.10	2.00e-155	542.00
IUUC-Aca-004846	Anolis carolinensis	88.69	0.00e+00	835.00
IUUC-Aly-005683	Arabidopsis lyrata	51.16	2.00e-122	432.00
IUUC-Ath-007661	Arabidopsis thaliana	51.07	2.00e-121	429.00
IUUC-Ago-007802	Ashbya gossypii	30.80	2.00e-58	220.00
IUUC-Acl-008304	Aspergillus clavatus	42.36	2.00e-93	336.00
IUUC-Afl-008735	Aspergillus flavus	58.82	6.00e-40	158.00
IUUC-Afu-009100	Aspergillus fumigatus	41.59	6.00e-92	332.00
IUUC-Ani-009138	Aspergillus nidulans	49.14	2.00e-95	343.00
IUUC-Ang-009661	Aspergillus niger	45.63	9.00e-98	351.00
IUUC-Aor-010235	Aspergillus oryzae	38.76	3.00e-80	293.00
IUUC-Ate-010346	Aspergillus terreus	37.94	2.00e-74	273.00
IUUC-Ame-011688	Astyanax mexicanus	93.60	0.00e+00	897.00
IUUC-Bgr-011998	Blumeria graminis	46.71	4.00e-114	405.00
IUUC-Bta-013407	Bos taurus	87.74	0.00e+00	865.00
IUUC-Bci-013977	Botrytis cinerea	47.39	8.00e-115	407.00
IUUC-Bdi-014361	Brachypodium distachyon	53.13	1.00e-134	473.00
IUUC-Bol-016317	Brassica oleracea	50.00	4.00e-120	425.00
IUUC-Bra-017952	Brassica rapa	51.06	6.00e-122	431.00
IUUC-Cel-018491	Caenorhabditis elegans	63.68	0.00e+00	635.00
IUUC-Cja-019134	Callithrix jacchus	86.21	0.00e+00	871.00
IUUC-Cfa-020098	Canis familiaris	86.21	0.00e+00	870.00
IUUC-Cpo-021595	Cavia porcellus	87.95	0.00e+00	866.00
IUUC-Cre-022886	Chlamydomonas reinhardtii	49.19	6.00e-31	125.00
IUUC-Csa-024121	Chlorocebus sabaeus	86.21	0.00e+00	871.00
IUUC-Cho-025057	Choloepus hoffmanni	70.94	1.00e-79	290.00
IUUC-Cin-025473	Ciona intestinalis	62.74	2.00e-62	232.00
IUUC-Csv-025815	Ciona savignyi	61.31	6.00e-176	610.00
IUUC-Cgl-026416	Colletotrichum gloeosporioides	43.40	3.00e-110	392.00
IUUC-Cne-026802	Cryptococcus neoformans	43.00	8.00e-102	364.00
IUUC-Dre-027870	Danio rerio	93.25	0.00e+00	895.00
IUUC-Dno-029655	Dasypus novemcinctus	87.71	0.00e+00	864.00
IUUC-Dor-030762	Dipodomys ordii	87.74	0.00e+00	864.00
IUUC-Dse-031441	Dothistroma septosporum	44.33	3.00e-109	389.00
IUUC-Dme-032101	Drosophila melanogaster	64.21	5.00e-180	624.00
IUUC-Ete-032841	Echinops telfairi	82.35	0.00e+00	827.00
IUUC-Eca-033463	Equus caballus	86.00	0.00e+00	868.00
IUUC-Eeu-034438	Erinaceus europaeus	62.73	1.00e-168	586.00
IUUC-Fca-035774	Felis catus	86.00	0.00e+00	870.00
IUUC-Fal-036988	Ficedula albicollis	88.15	0.00e+00	867.00
IUUC-Fox-037895	Fusarium oxysporum	44.99	7.00e-108	384.00
IUUC-Fso-038450	Fusarium solani	45.63	6.00e-109	387.00
IUUC-Gmo-038874	Gadus morhua	90.95	0.00e+00	889.00
IUUC-Ggr-040115	Gaeumannomyces graminis	44.19	6.00e-104	371.00
IUUC-Gac-041650	Gasterosteus aculeatus	94.57	0.00e+00	938.00
IUUC-Gma-043697	Glycine max	52.08	3.00e-133	469.00
IUUC-Ggo-044707	Gorilla gorilla	80.53	0.00e+00	795.00
IUUC-Hsa-046041	Homo sapiens	86.21	0.00e+00	870.00
IUUC-Hvu-047816	Hordeum vulgare	51.29	1.00e-122	433.00
IUUC-Itr-048945	Ictidomys tridecemlineatus	86.76	3.00e-175	607.00
IUUC-Lch-050419	Latimeria chalumnae	89.68	0.00e+00	879.00
IUUC-Lpe-051593	Leersia perrieri	53.73	4.00e-136	478.00
IUUC-Loc-052930	Lepisosteus oculatus	90.42	0.00e+00	905.00
IUUC-Lma-053256	Leptosphaeria maculans	46.75	1.00e-113	403.00
IUUC-Laf-053555	Loxodonta africana	85.63	0.00e+00	864.00
IUUC-Mcc-055630	Macaca mulatta	86.21	0.00e+00	871.00
IUUC-Meu-056579	Macropus eugenii	84.59	1.00e-158	553.00
IUUC-Mor-057078	Magnaporthe oryzae	44.97	7.00e-107	381.00
IUUC-Mpo-057607	Magnaporthe poae	38.57	8.00e-84	304.00
IUUC-Mtr-058644	Medicago truncatula	53.07	9.00e-131	460.00
IUUC-Mla-059120	Melampsora laricipopulina	41.86	6.00e-100	358.00
IUUC-Mvi-060429	Microbotryum violaceum	46.18	5.00e-71	261.00
IUUC-Mmr-061313	Microcebus murinus	86.33	0.00e+00	868.00
IUUC-Mdo-062801	Monodelphis domestica	86.15	0.00e+00	869.00
IUUC-Mmu-064424	Mus musculus	87.95	0.00e+00	879.00
IUUC-Mac-064694	Musa acuminata	53.12	3.00e-131	462.00
IUUC-Mpu-065980	Mustela putorius furo	88.43	0.00e+00	760.00
IUUC-Mlu-067007	Myotis lucifugus	87.08	0.00e+00	865.00
IUUC-Nfi-068274	Neosartorya fischeri	41.59	4.00e-92	332.00
IUUC-Ncr-068829	Neurospora crassa	47.20	3.00e-107	382.00
IUUC-Nle-069171	Nomascus leucogenys	87.71	0.00e+00	862.00
IUUC-Opr-070494	Ochotona princeps	80.55	0.00e+00	769.00
IUUC-Oan-073099	Ornithorhynchus anatinus	87.53	0.00e+00	860.00
IUUC-Ocu-074642	Oryctolagus cuniculus	85.95	0.00e+00	866.00
IUUC-Oba-075886	Oryza barthii	53.52	4.00e-136	478.00
IUUC-Obr-076220	Oryza brachyantha	53.30	4.00e-136	478.00
IUUC-Ogl-077682	Oryza glaberrima	53.52	3.00e-136	478.00
IUUC-Ogu-078492	Oryza glumaepatula	53.30	4.00e-136	478.00
IUUC-Oin-079956	Oryza indica	53.52	3.00e-136	478.00
IUUC-Olo-080239	Oryza longistaminata	47.99	5.00e-109	389.00
IUUC-Ome-081573	Oryza meridionalis	53.52	1.00e-136	480.00
IUUC-Oni-082975	Oryza nivara	53.52	3.00e-136	478.00
IUUC-Opu-083724	Oryza punctata	53.73	2.00e-136	479.00
IUUC-Oru-084566	Oryza rufipogon	53.52	3.00e-136	478.00
IUUC-Osa-086008	Oryza sativa	53.52	3.00e-136	478.00
IUUC-Ola-086967	Oryzias latipes	96.46	0.00e+00	919.00
IUUC-Olu-087614	Ostreococcus lucimarinus	42.92	3.00e-97	348.00
IUUC-Oga-088047	Otolemur garnettii	70.94	2.00e-161	562.00
IUUC-Oar-089393	Ovis aries	86.00	0.00e+00	868.00
IUUC-Ptr-090561	Pan troglodytes	86.21	0.00e+00	870.00
IUUC-Pan-091812	Papio anubis	86.21	0.00e+00	871.00
IUUC-Psi-093507	Pelodiscus sinensis	86.53	2.00e-149	521.00
IUUC-Pno-095104	Phaeosphaeria nodorum	45.61	9.00e-111	394.00
IUUC-Ppa-095995	Physcomitrella patens	53.12	1.00e-137	483.00
IUUC-Pfo-096754	Poecilia formosa	93.82	0.00e+00	926.00
IUUC-Pab-098053	Pongo abelii	86.21	0.00e+00	870.00
IUUC-Pop-099230	Populus trichocarpa	52.07	1.00e-137	483.00
IUUC-Pca-100407	Procavia capensis	78.70	0.00e+00	772.00
IUUC-Ppe-101699	Prunus persica	51.49	4.00e-131	461.00
IUUC-Pva-103159	Pteropus vampyrus	83.77	0.00e+00	822.00
IUUC-Pgr-103433	Puccinia graminis	42.83	6.00e-106	378.00
IUUC-Ptt-103701	Puccinia triticina	40.08	2.00e-94	340.00
IUUC-Pte-104281	Pyrenophora teres	46.96	2.00e-113	402.00
IUUC-Pyt-104714	Pyrenophora triticirepentis	46.96	3.00e-113	402.00
IUUC-Rno-105531	Rattus norvegicus	85.83	0.00e+00	883.00
IUUC-Sce-106368	Saccharomyces cerevisiae	30.34	3.00e-46	179.00
IUUC-Sha-107093	Sarcophilus harrisii	86.15	0.00e+00	864.00
IUUC-Sja-108004	Schizosaccharomyces japonicus	44.37	1.00e-114	407.00
IUUC-Spo-108018	Schizosaccharomyces pombe	46.17	1.00e-113	403.00
IUUC-Ssl-108460	Sclerotinia sclerotiorum	44.21	1.00e-106	380.00
IUUC-Smo-108892	Selaginella moellendorffii	53.73	5.00e-136	477.00
IUUC-Sit-110782	Setaria italica	54.62	5.00e-138	484.00
IUUC-Sly-111308	Solanum lycopersicum	53.21	9.00e-141	493.00
IUUC-Stu-112447	Solanum tuberosum	53.42	2.00e-141	495.00
IUUC-Sar-113352	Sorex araneus	81.16	0.00e+00	689.00
IUUC-Sbi-114806	Sorghum bicolor	55.17	5.00e-137	481.00
IUUC-Sre-115059	Sporisorium reilianum	40.55	1.00e-92	334.00
IUUC-Ssc-115677	Sus scrofa	83.70	2.00e-175	608.00
IUUC-Tru-118478	Takifugu rubripes	92.40	0.00e+00	946.00
IUUC-Tsy-119082	Tarsius syrichta	76.81	0.00e+00	647.00
IUUC-Tni-120419	Tetraodon nigroviridis	92.00	0.00e+00	924.00
IUUC-Tca-121294	Theobroma cacao	53.32	8.00e-140	490.00
IUUC-Tre-121962	Trichoderma reesei	45.49	1.00e-103	370.00
IUUC-Tvi-122280	Trichoderma virens	45.14	2.00e-111	396.00
IUUC-Tae-124442	Triticum aestivum	54.43	1.00e-136	480.00
IUUC-Tur-126551	Triticum urartu	54.43	2.00e-136	479.00
IUUC-Tme-126959	Tuber melanosporum	46.17	7.00e-117	414.00
IUUC-Tbe-127737	Tupaia belangeri	88.34	0.00e+00	826.00
IUUC-Ttr-129211	Tursiops truncatus	86.72	1.00e-138	486.00
IUUC-Uma-129591	Ustilago maydis	39.58	9.00e-97	347.00
IUUC-Vda-129674	Verticillium dahliae	43.76	1.00e-96	347.00
IUUC-Vpa-130793	Vicugna pacos	82.74	0.00e+00	760.00
IUUC-Xtr-132430	Xenopus tropicalis	86.05	0.00e+00	847.00
IUUC-Xma-133515	Xiphophorus maculatus	93.95	0.00e+00	917.00
IUUC-Yli-134488	Yarrowia lipolytica	37.97	2.00e-76	279.00
IUUC-Zma-134748	Zea mays	55.36	3.00e-138	485.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence