iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054192

UUCD1 version

UUC-LoA-00113

Ensembl Protein ID

ENSLAFP00000002753.3

UniProt Accession

G3SS50; G3SS50_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SPOP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003311.3	ENSLAFT00000003311.3	ENSLAFP00000002753.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.70e-33	113.0	201	267
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.80e-09	35.1	300	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++l+v+g+ef+ahk++Laa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 201  TDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNL 267
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eN+++il +Adl+++++Lk +a+dfi++h 
   Q: 300  VENAAEILILADLHSADQLKTQAVDFINYHA 330
           79***************************95 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSRVPSPPPP AEMSSGPVAE SWCYTQQIKV VKFSYMWTIN NFSFCREEMG EVIKSSTFSS 60
GANDKLKWCL RVNPKGLDEE SKDYLSLYLL LVSCPKSEVR AKFKFSILNA KGEETKAMES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGGG TTCCAAGTCC TCCACCTCCG GCAGAAATGT CGAGTGGCCC TGTAGCTGAG 60
AGCTGGTGCT ACACACAGGT AAGTTCATGT TTTCTCTCTG TAAATCTTGA TCTTGGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016607--C:nuclear speck
GO:0042593--P:glucose homeostasis
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676--P:positive regulation of type B pancreatic cell apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000920	Aegilops tauschii	31.44	2.00e-40	159.00
IUUC-Aml-002307	Ailuropoda melanoleuca	95.42	0.00e+00	707.00
IUUC-Apl-003488	Anas platyrhynchos	99.47	0.00e+00	711.00
IUUC-Aca-005010	Anolis carolinensis	99.20	0.00e+00	709.00
IUUC-Aly-005426	Arabidopsis lyrata	29.86	4.00e-41	162.00
IUUC-Afl-008594	Aspergillus flavus	38.46	1.00e-03	36.20
IUUC-Aor-009945	Aspergillus oryzae	38.46	3.00e-04	36.60
IUUC-Bgr-012157	Blumeria graminis	35.00	1.00e-04	40.00
IUUC-Bta-012931	Bos taurus	99.73	0.00e+00	712.00
IUUC-Bdi-014743	Brachypodium distachyon	32.55	2.00e-43	169.00
IUUC-Bol-015794	Brassica oleracea	30.34	2.00e-41	163.00
IUUC-Cel-018671	Caenorhabditis elegans	65.71	3.00e-134	471.00
IUUC-Cja-019981	Callithrix jacchus	100.00	0.00e+00	719.00
IUUC-Cfa-020115	Canis familiaris	99.73	0.00e+00	712.00
IUUC-Cpo-021366	Cavia porcellus	99.73	0.00e+00	717.00
IUUC-Cre-022954	Chlamydomonas reinhardtii	30.99	2.00e-06	48.50
IUUC-Cin-025636	Ciona intestinalis	76.34	7.00e-158	549.00
IUUC-Cgl-026729	Colletotrichum gloeosporioides	30.30	7.00e-06	45.10
IUUC-Dre-027603	Danio rerio	97.07	0.00e+00	693.00
IUUC-Dno-029006	Dasypus novemcinctus	94.20	0.00e+00	652.00
IUUC-Dor-030503	Dipodomys ordii	99.73	0.00e+00	704.00
IUUC-Dme-032218	Drosophila melanogaster	79.47	9.00e-159	553.00
IUUC-Ete-032328	Echinops telfairi	99.43	0.00e+00	655.00
IUUC-Eca-033238	Equus caballus	99.73	0.00e+00	712.00
IUUC-Eeu-034739	Erinaceus europaeus	83.73	9.00e-175	605.00
IUUC-Fca-035435	Felis catus	99.73	0.00e+00	712.00
IUUC-Gmo-038600	Gadus morhua	95.73	0.00e+00	688.00
IUUC-Gga-040441	Gallus gallus	99.47	0.00e+00	711.00
IUUC-Gac-041911	Gasterosteus aculeatus	96.53	0.00e+00	692.00
IUUC-Gma-044158	Glycine max	31.22	2.00e-42	166.00
IUUC-Hsa-045835	Homo sapiens	99.73	0.00e+00	712.00
IUUC-Hvu-047439	Hordeum vulgare	32.10	2.00e-36	145.00
IUUC-Itr-048058	Ictidomys tridecemlineatus	97.57	0.00e+00	677.00
IUUC-Lch-050241	Latimeria chalumnae	98.40	0.00e+00	705.00
IUUC-Loc-052374	Lepisosteus oculatus	98.67	0.00e+00	706.00
IUUC-Lma-053106	Leptosphaeria maculans	23.53	2.00e-08	51.60
IUUC-Mcc-055322	Macaca mulatta	99.73	0.00e+00	712.00
IUUC-Meu-056330	Macropus eugenii	92.53	0.00e+00	656.00
IUUC-Mor-057237	Magnaporthe oryzae	29.41	8.00e-08	50.80
IUUC-Mpo-057466	Magnaporthe poae	28.36	6.00e-08	50.80
IUUC-Mtr-058679	Medicago truncatula	30.14	8.00e-41	160.00
IUUC-Mga-059579	Meleagris gallopavo	94.91	0.00e+00	697.00
IUUC-Mmr-061309	Microcebus murinus	99.73	0.00e+00	712.00
IUUC-Mmu-064227	Mus musculus	99.73	0.00e+00	712.00
IUUC-Mac-065306	Musa acuminata	31.27	3.00e-43	169.00
IUUC-Mpu-065693	Mustela putorius furo	99.73	0.00e+00	712.00
IUUC-Mlu-067827	Myotis lucifugus	99.73	0.00e+00	716.00
IUUC-Nle-069393	Nomascus leucogenys	99.73	0.00e+00	712.00
IUUC-Opr-070490	Ochotona princeps	97.87	0.00e+00	696.00
IUUC-Ont-071726	Oreochromis niloticus	96.80	0.00e+00	694.00
IUUC-Ocu-074932	Oryctolagus cuniculus	99.73	0.00e+00	712.00
IUUC-Obr-076031	Oryza brachyantha	28.65	1.00e-32	134.00
IUUC-Ogu-078752	Oryza glumaepatula	34.62	1.00e-38	154.00
IUUC-Olo-080833	Oryza longistaminata	32.56	2.00e-37	149.00
IUUC-Ome-081184	Oryza meridionalis	33.07	5.00e-39	155.00
IUUC-Opu-083303	Oryza punctata	32.20	6.00e-29	122.00
IUUC-Oru-085193	Oryza rufipogon	30.68	3.00e-41	164.00
IUUC-Ola-086989	Oryzias latipes	96.54	0.00e+00	689.00
IUUC-Olu-087691	Ostreococcus lucimarinus	31.73	2.00e-35	142.00
IUUC-Oga-089107	Otolemur garnettii	99.73	0.00e+00	712.00
IUUC-Oar-089943	Ovis aries	100.00	0.00e+00	719.00
IUUC-Ptr-091201	Pan troglodytes	99.73	0.00e+00	712.00
IUUC-Pan-092504	Papio anubis	99.73	0.00e+00	712.00
IUUC-Psi-093063	Pelodiscus sinensis	99.47	0.00e+00	711.00
IUUC-Pma-094310	Petromyzon marinus	85.00	2.00e-167	581.00
IUUC-Ppa-095322	Physcomitrella patens	31.48	2.00e-41	162.00
IUUC-Pfo-096411	Poecilia formosa	96.80	0.00e+00	694.00
IUUC-Pab-098640	Pongo abelii	99.73	0.00e+00	712.00
IUUC-Pop-099525	Populus trichocarpa	31.27	4.00e-30	125.00
IUUC-Pca-100243	Procavia capensis	84.04	3.00e-131	460.00
IUUC-Pva-102296	Pteropus vampyrus	92.80	0.00e+00	644.00
IUUC-Pyt-104526	Pyrenophora triticirepentis	23.53	9.00e-07	47.40
IUUC-Rno-105399	Rattus norvegicus	99.73	0.00e+00	712.00
IUUC-Sha-106700	Sarcophilus harrisii	99.20	0.00e+00	709.00
IUUC-Spo-108262	Schizosaccharomyces pombe	36.84	1.00e-01	32.30
IUUC-Ssl-108548	Sclerotinia sclerotiorum	28.77	1.00e-06	47.00
IUUC-Smo-108684	Selaginella moellendorffii	31.35	7.00e-31	127.00
IUUC-Sit-109872	Setaria italica	33.43	9.00e-42	164.00
IUUC-Sly-110931	Solanum lycopersicum	29.46	2.00e-43	169.00
IUUC-Stu-112216	Solanum tuberosum	29.97	6.00e-43	168.00
IUUC-Sar-113489	Sorex araneus	99.73	0.00e+00	712.00
IUUC-Sbi-114704	Sorghum bicolor	34.35	1.00e-41	164.00
IUUC-Tru-117832	Takifugu rubripes	96.00	0.00e+00	688.00
IUUC-Tsy-118969	Tarsius syrichta	94.67	0.00e+00	666.00
IUUC-Tni-120221	Tetraodon nigroviridis	96.00	0.00e+00	688.00
IUUC-Tca-121715	Theobroma cacao	30.67	4.00e-45	175.00
IUUC-Tae-122976	Triticum aestivum	31.73	6.00e-41	161.00
IUUC-Tbe-127298	Tupaia belangeri	99.20	0.00e+00	698.00
IUUC-Ttr-128952	Tursiops truncatus	99.47	0.00e+00	711.00
IUUC-Vda-129835	Verticillium dahliae	42.00	7.00e-07	49.30
IUUC-Vpa-130735	Vicugna pacos	93.87	0.00e+00	640.00
IUUC-Vvi-130854	Vitis vinifera	31.65	5.00e-32	131.00
IUUC-Xtr-132806	Xenopus tropicalis	97.88	0.00e+00	697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence